Adrian P Gee

Adrian P Gee

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Adrian P Gee

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Regulation of Regenerative Medicine Products.

Authors:
Adrian P Gee

Adv Exp Med Biol 2018 ;1098:189-198

cGMP Facilities, Center for Cell & Gene Therapy, Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.1007/978-3-319-97421-7_10DOI Listing
February 2019

In Vivo Fate and Activity of Second- versus Third-Generation CD19-Specific CAR-T Cells in B Cell Non-Hodgkin's Lymphomas.

Mol Ther 2018 12 13;26(12):2727-2737. Epub 2018 Sep 13.

Center for Cell and Gene Therapy, Baylor College of Medicine, Houston Methodist Hospital and Texas Children's Hospital, Houston, TX 77030, USA; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2018.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277484PMC
December 2018

GMP CAR-T cell production.

Authors:
Adrian P Gee

Best Pract Res Clin Haematol 2018 06 2;31(2):126-134. Epub 2018 Feb 2.

cGMP Facilities, Center for Cell & Gene Therapy, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.beha.2018.01.002DOI Listing
June 2018

Tumor-Specific T-Cells Engineered to Overcome Tumor Immune Evasion Induce Clinical Responses in Patients With Relapsed Hodgkin Lymphoma.

J Clin Oncol 2018 04 9;36(11):1128-1139. Epub 2018 Jan 9.

Catherine M. Bollard, Tamara Tripic, Gianpietro Dotti, Stephen Gottschalk, Vicky Torrano, Olga Dakhova, George Carrum, Carlos A. Ramos, Adrian P. Gee, Malcolm K. Brenner, Helen E. Heslop, and Cliona M. Rooney, Houston Methodist Hospital, and Texas Children's Hospital; Catherine M. Bollard, Gianpietro Dotti, Stephen Gottschalk, George Carrum, Carlos A. Ramos, Hao Liu, Meng-Fen Wu, Andrea N. Marcogliese, Adrian P. Gee, Malcolm K. Brenner, Helen E. Heslop, and Cliona M. Rooney, Baylor College of Medicine, Houston, TX; Catherine M. Bollard, Conrad Russell Cruz, and Cecilia Barese, Children's National Health System, Washington, DC; Youli Zu and Daniel Y. Lee, Weill Medical College of Cornell University; and Owen O'Connor, Columbia University College of Physicians and Surgeons, The New York Presbyterian Hospital, New York, NY.

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http://ascopubs.org/doi/10.1200/JCO.2017.74.3179
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http://dx.doi.org/10.1200/JCO.2017.74.3179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891126PMC
April 2018

TIME Trial: Effect of Timing of Stem Cell Delivery Following ST-Elevation Myocardial Infarction on the Recovery of Global and Regional Left Ventricular Function: Final 2-Year Analysis.

Circ Res 2018 02 5;122(3):479-488. Epub 2017 Dec 5.

From the Department of Cardiology, Minneapolis Heart Institute Foundation, Abbott Northwestern Hospital, MN (J.H.T., T.D.H.); Department of Medicine, University of Minnesota School of Medicine, Minneapolis (J.H.T., G.R.); Department of Medicine, Cedars Sinai Medical Center, Los Angeles, CA (T.D.H.); Department of Medicine, College of Medicine, University of Florida, Gainesville (C.J.P., J.R.F.); Stem Cell Center (J.T.W., E.C.P.), and Regenerative Medicine Research (D.A.T.), Texas Heart Institute, CHI St. Luke's Health Baylor College of Medicine Medical Center, Houston; Franciscan Saint Francis Health, Indianapolis, IN (A.C.); Department of Cardiovascular Medicine, Stanford University School of Medicine, CA (P.C.Y.); Department of Cardiology, Wake Forest University School of Medicine, Winston-Salem, NC (D.X.M.Z.); Department of Cardiovascular Medicine, Cleveland Clinic Foundation, OH (S.G.E.); Summa Health Heart and Vascular Institute, Akron, OH (M.S.P.); Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN (A.K.H.); Metropolitan Heart and Vascular Institute, Mercy Hospital, Coon Rapids, MN (J.C.C.); United Heart and Vascular Clinic (K.W.B.); Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX (A.P.G.); Coordinating Center for Clinical Trials, UTHealth School of Public Health, Houston, TX (L.M.); National Heart Lung, and Blood Institute, Bethesda, MD (R.F.E.); and University of Kansas School of Medicine (R.D.S.).

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http://dx.doi.org/10.1161/CIRCRESAHA.117.311466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805626PMC
February 2018

Absence of Replication-Competent Retrovirus in Vectors, T Cell Products, and Patient Follow-Up Samples.

Mol Ther 2018 01 9;26(1):6-7. Epub 2017 Dec 9.

Center for Cell and Gene Therapy, Baylor College of Medicine, Houston Methodist Hospital and Texas Children's Hospital, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2017.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763145PMC
January 2018

Large-Scale Culture and Genetic Modification of Human Natural Killer Cells for Cellular Therapy.

Methods Mol Biol 2016 ;1441:195-202

Center for Cell and Gene Therapy, Baylor College of Medicine, Texas Children's Hospital, Houston Methodist Hospital, 1102 Bates St, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1007/978-1-4939-3684-7_16DOI Listing
December 2017

Off-the-Shelf Virus-Specific T Cells to Treat BK Virus, Human Herpesvirus 6, Cytomegalovirus, Epstein-Barr Virus, and Adenovirus Infections After Allogeneic Hematopoietic Stem-Cell Transplantation.

J Clin Oncol 2017 Nov 7;35(31):3547-3557. Epub 2017 Aug 7.

Ifigeneia Tzannou, Anastasia Papadopoulou, Swati Naik, Kathryn Leung, Caridad A. Martinez, Carlos A. Ramos, George Carrum, Ghadir Sasa, Premal Lulla, Ayumi Watanabe, Manik Kuvalekar, Adrian P. Gee, Bambi J. Grilley, Robert A. Krance, Stephen Gottschalk, Malcolm K. Brenner, Cliona M. Rooney, Helen E. Heslop, Ann M. Leen, and Bilal Omer, Center for Cell and Gene Therapy, Baylor College of Medicine, Texas Children's Hospital, and Houston Methodist Hospital; Meng-Fen Wu and Hao Liu, Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX.

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http://dx.doi.org/10.1200/JCO.2017.73.0655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662844PMC
November 2017

Clinical and immunological responses after CD30-specific chimeric antigen receptor-redirected lymphocytes.

J Clin Invest 2017 Sep 14;127(9):3462-3471. Epub 2017 Aug 14.

Center for Cell and Gene Therapy, Baylor College of Medicine, Houston Methodist Hospital and Texas Children's Hospital, Houston, Texas, USA.

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http://dx.doi.org/10.1172/JCI94306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669573PMC
September 2017

Evaluation of Cell Therapy on Exercise Performance and Limb Perfusion in Peripheral Artery Disease: The CCTRN PACE Trial (Patients With Intermittent Claudication Injected With ALDH Bright Cells).

Circulation 2017 Apr 16;135(15):1417-1428. Epub 2017 Feb 16.

From Texas Heart Institute (E.C.P., J.T.W., A.G., D.A.T., M.R., B.C., N.P.), CHI St. Luke's Health (R.M.), Houston; Indiana University School of Medicine, Indianapolis (M.P.M., K.L.M., P.G.); University of Louisville, KY (R.B., J.L., S.W.); Stanford University School of Medicine, CA (P.C.Y., N.J.L., R.L.D., F.K., E.G.R., M.R.S.); Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital, MN (J.A., J.H.T., J.G.); Cedars-Sinai Heart Institute, Los Angeles, CA (T.D.H.); University of Florida School of Medicine, Gainesville (C.J.P., R.D.A., S.B., D.L., E.H.); University of Minnesota Medical School, Minneapolis (G.R., B.B.-D., E.C., A.T.H.); University of Miami Miller School of Medicine, FL (O.V., J.M.H., I.H.S., D.D.); Orlando Health, FL (V.S.K.); University of Colorado School of Medicine and CPC Clinical Research, Aurora (W.R.H.); Johns Hopkins University, Baltimore, MD (B.A.- V., J.A.L.); Baylor College of Medicine, Houston, TX (A.P.G., A.G.D., J. Bloom, S.R.); University of Texas School of Public Health, Houston (J. Bettencourt, D.L., L.P., L.S., M.C., S.L.S., R.W.V., L.M.); National Institutes of Health, National Heart, Lung, and Blood Institute, Bethesda, MD (R.F.E.); and University of Kansas School of Medicine, Kansas City (R.D.S.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.025707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388585PMC
April 2017

A reproducible immunopotency assay to measure mesenchymal stromal cell-mediated T-cell suppression.

Cytotherapy 2015 Feb 21;17(2):140-51. Epub 2014 Nov 21.

Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA; University of Wisconsin Carbone Cancer Center, Madison, Wisconsin, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jcyt.2014.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297551PMC
February 2015

CD34 measurement: setting standards.

Authors:
Adrian P Gee

Cytotherapy 2014 Nov;16(11):1451-1452

Center for Cell & Gene Therapy, Baylor College of Medicine, Houston, Texas, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jcyt.2014.09.001DOI Listing
November 2014

Closely related T-memory stem cells correlate with in vivo expansion of CAR.CD19-T cells and are preserved by IL-7 and IL-15.

Blood 2014 Jun 29;123(24):3750-9. Epub 2014 Apr 29.

Center for Cell and Gene Therapy, Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX; Department of Medicine, Baylor College of Medicine, Houston, TX; Texas Children's Hospital, Houston, TX.

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http://www.bloodjournal.org/content/bloodjournal/123/24/3750
Web Search
http://www.bloodjournal.org/cgi/doi/10.1182/blood-2014-01-55
Publisher Site
http://dx.doi.org/10.1182/blood-2014-01-552174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055922PMC
June 2014

HLA-restricted NY-ESO-1 peptide immunotherapy for metastatic castration resistant prostate cancer.

Invest New Drugs 2014 Apr 23;32(2):235-242. Epub 2013 Apr 23.

Department of Medicine, Section of Medical Oncology, Baylor College of Medicine, Houston, TX, USA; Michael E. DeBakey Veterans Affairs Medical Center, VA 111H, 2002 Holcombe Blvd, Houston, TX 77030, USA.

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http://dx.doi.org/10.1007/s10637-013-9960-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100683PMC
April 2014

Sustained complete responses in patients with lymphoma receiving autologous cytotoxic T lymphocytes targeting Epstein-Barr virus latent membrane proteins.

J Clin Oncol 2014 Mar 16;32(8):798-808. Epub 2013 Dec 16.

Catherine M. Bollard, Stephen Gottschalk, Vicky Torrano, Oumar Diouf, Stephanie Ku, Yasmin Hazrat, George Carrum, Carlos Ramos, Hao Liu, Meng-Fen Wu, Andrea M. Sheehan, Adrian P. Gee, Malcolm K. Brenner, Helen E. Heslop, and Cliona M. Rooney, Baylor College of Medicine and Texas Children's Hospital; Catherine M. Bollard, Stephen Gottschalk, Vicky Torrano, Oumar Diouf, Stephanie Ku, Yasmin Hazrat, George Carrum, Carlos Ramos, Hao Liu, Meng-Fen Wu, Daniel Lee, Andrea M. Sheehan, Youli Zu, Adrian P. Gee, Malcolm K. Brenner, Helen E. Heslop, and Cliona M. Rooney, Methodist Hospital; Luis Fayad, Elizabeth J. Shpall, and Barbara Pro, MD Anderson Cancer Center, Houston, TX; and Daniel Lee and Youli Zu, Weill Medical College of Cornell University, New York, NY.

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http://dx.doi.org/10.1200/JCO.2013.51.5304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940538PMC
March 2014

Manufacturing mesenchymal stromal cells for phase I clinical trials.

Cytotherapy 2013 Apr;15(4):416-22

Center for Cell and Gene Therapy, Baylor College of Medicine, Texas Children's Hospital and The Methodist Hospital, Houston, TX, USA.

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http://dx.doi.org/10.1016/j.jcyt.2012.09.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3611961PMC
April 2013

Good manufacturing practice-grade cytotoxic T lymphocytes specific for latent membrane proteins (LMP)-1 and LMP2 for patients with Epstein-Barr virus-associated lymphoma.

Cytotherapy 2011 May 1;13(5):518-22. Epub 2011 Mar 1.

Center for Cell and Gene Therapy, Department of Pediatrics, Baylor College of Medicine, The Methodist Hospital and Texas Children's Hospital, Houston, Texas 77030, USA.

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http://dx.doi.org/10.3109/14653249.2011.561983DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186062PMC
May 2011

Cytotoxic T lymphocyte therapy with donor T cells prevents and treats adenovirus and Epstein-Barr virus infections after haploidentical and matched unrelated stem cell transplantation.

Blood 2009 Nov 21;114(19):4283-92. Epub 2009 Aug 21.

Center for Cell and Gene Therapy and Departments of Pediatrics, Immunology, Medicine, and Virology, Baylor College of Medicine, Texas Children's Hospital and the Methodist Hospital, Houston, TX 77030, USA.

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http://dx.doi.org/10.1182/blood-2009-07-232454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774556PMC
November 2009

Cell therapies for traumatic brain injury.

Neurosurg Focus 2008 ;24(3-4):E18

Department of Pediatric Surgery, University of Texas Medical School at Houston, Texas 77030, USA.

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http://dx.doi.org/10.3171/FOC/2008/24/3-4/E17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721356PMC
April 2008

Identification of hexon-specific CD4 and CD8 T-cell epitopes for vaccine and immunotherapy.

J Virol 2008 Jan 17;82(1):546-54. Epub 2007 Oct 17.

Center for Cell and Gene Therapy, Baylor College of Medicine, 6621 Fannin Street, MC 3-3320, Houston, TX 77030, USA.

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http://dx.doi.org/10.1128/JVI.01689-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2224388PMC
January 2008

Treatment of solid organ transplant recipients with autologous Epstein Barr virus-specific cytotoxic T lymphocytes (CTLs).

Blood 2006 Nov 11;108(9):2942-9. Epub 2006 Jul 11.

Center for Cell and Gene Therapy, Department of Pediatrics, Baylor College of Medicine, The Methodist Hospital and Texas Children's Hospital, 6621 Fannin St, MC 3-3320, Houston, TX 77030, USA.

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http://dx.doi.org/10.1182/blood-2006-05-021782DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895521PMC
November 2006

Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals.

Nat Med 2006 Oct 24;12(10):1160-6. Epub 2006 Sep 24.

Center for Cell and Gene Therapy, Baylor College of Medicine, The Methodist Hospital and Texas Children's Hospital, Houston, Texas 77030, USA.

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http://www.nature.com/articles/nm1475
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http://dx.doi.org/10.1038/nm1475DOI Listing
October 2006

Treatment of nasopharyngeal carcinoma with Epstein-Barr virus--specific T lymphocytes.

Blood 2005 Mar 12;105(5):1898-904. Epub 2004 Nov 12.

Center for Cell and Gene Therapy, Department of Pediatrics, Baylor College of Medicine, 1102 Bates St, Suite 1120, Houston, TX 77030, USA.

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http://dx.doi.org/10.1182/blood-2004-07-2975DOI Listing
March 2005

Prompt versus preemptive intervention for EBV lymphoproliferative disease.

Blood 2004 May 29;103(10):3979-81. Epub 2004 Jan 29.

Departments of Pediatrics and Medicine, Baylor College of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1182/blood-2003-12-4287DOI Listing
May 2004

[Impact of regulations on translational research in cell and gene therapy: the American experience].

Bull Cancer 2004 Mar;91(3):239-47

Center for Cell and Gene Therapy, Baylor College of Medicine, 6621 Fannin, MC 3-3320, Houston, Texas 77030, USA.

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March 2004

Regulatory issues in cellular therapies.

Authors:
Adrian P Gee

Expert Opin Biol Ther 2003 Jul;3(4):537-40

Center for Cell & Gene Therapy, Baylor College of Medicine, 6621 Fannin Street, MC 3-3320, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1517/14712598.3.4.537 DOI Listing
July 2003

Regulatory issues in cellular therapies.

Authors:
Adrian P Gee

J Cell Biochem Suppl 2002 ;38:104-12

Center for Cell and Gene Therapy, Baylor College of Medicine Houston, Texas 77030, USA.

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November 2002

The impact of regulatory policy on the development of somatic cell therapies in the United States.

Authors:
Adrian P Gee

Transpl Immunol 2002 May;9(2-4):295-300

Center For Cell and Gene Therapy, Baylor College of Medicine, Feigin Center, Houston, TX 77030, USA.

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May 2002

Generation of EBV-specific CD4+ cytotoxic T cells from virus naive individuals.

J Immunol 2002 Jan;168(2):909-18

Center for Cell and Gene Therapy and Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.4049/jimmunol.168.2.909DOI Listing
January 2002