Adrian M Jubb

Adrian M Jubb

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Adrian M Jubb

Adrian M Jubb

Publications by authors named "Adrian M Jubb"

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A death receptor 6-amyloid precursor protein pathway regulates synapse density in the mature CNS but does not contribute to Alzheimer's disease-related pathophysiology in murine models.

J Neurosci 2014 May;34(19):6425-37

Departments of Biomedical Imaging, Neuroscience, and Pathology, Genentech Inc., South San Francisco, California 94080, Stanford Behavioral and Functional Neuroscience Laboratory, Stanford University, Stanford, California 94305, and Laboratory of Brain Development and Repair, The Rockefeller University, New York, New York 10065.

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http://dx.doi.org/10.1523/JNEUROSCI.4963-13.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608138PMC
May 2014

DUOX2 and DUOXA2 form the predominant enzyme system capable of producing the reactive oxygen species H2O2 in active ulcerative colitis and are modulated by 5-aminosalicylic acid.

Inflamm Bowel Dis 2014 Mar;20(3):514-24

*Centre for Digestive Diseases, Blizard Institute, Barts and The London School of Medicine and Dentistry, Whitechapel, London, United Kingdom; †National Centre for Bowel Research and Surgical Innovation, Barts and The London School of Medicine and Dentistry, Whitechapel, London, United Kingdom; ‡Flow Cytometry Core Facility, Blizard Institute, Barts and The London School of Medicine and Dentistry, Whitechapel, London, United Kingdom; §Department of Pathology, Medical Faculty, Otto-von-Guericke University Magdeburg, Magdeburg, Germany; ‖Department of Cellular Pathology, Royal London Hospital, London, United Kingdom; ¶Division of Pulmonary and Critical Care Medicine, Genome and Biomedical Sciences Facility, University of California at Davis, Davis, California; and **Department of Pathology, Genentech, Inc., South San Francisco, California.

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http://pdfs.journals.lww.com/ibdjournal/2014/03000/DUOX2_and
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/01.MIB.0000442012.45038.0eDOI Listing
March 2014

Lymph node-independent liver metastasis in a model of metastatic colorectal cancer.

Nat Commun 2014 Mar 26;5:3530. Epub 2014 Mar 26.

Department of Discovery Oncology, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.

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http://dx.doi.org/10.1038/ncomms4530DOI Listing
March 2014

Pathology in drug discovery and development.

J Pathol 2014 Jan;232(2):99-102

Department of Product Development - Oncology, Genentech Inc., South San Francisco, CA, USA.

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http://dx.doi.org/10.1002/path.4290DOI Listing
January 2014

Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration.

J Exp Med 2013 Nov 28;210(12):2553-67. Epub 2013 Oct 28.

Department of Neuroscience, 2 Department of Biomedical Imaging, 3 Department of Bioinformatics and Computational Biology, 4 Department of Protein Chemistry, 5 Department of Pathology, Genentech, Inc., South San Francisco, CA 94080.

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http://dx.doi.org/10.1084/jem.20122832DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832926PMC
November 2013

Impact of MET expression on outcome in BRAF(V600E/K) advanced melanoma.

Histopathology 2013 Sep 26;63(3):351-61. Epub 2013 Jun 26.

Product Development-Oncology, Genentech Inc., South San Francisco, CA, USA.

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http://dx.doi.org/10.1111/his.12169DOI Listing
September 2013

Predictive impact of circulating vascular endothelial growth factor in four phase III trials evaluating bevacizumab.

Clin Cancer Res 2013 Feb 20;19(4):929-37. Epub 2012 Nov 20.

Department of Oncology Biomarkers, Genentech, Inc., South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-2535DOI Listing
February 2013

Prognostic and predictive significance of proliferation in 867 colorectal cancers.

J Clin Pathol 2012 Nov 2;65(11):989-95. Epub 2012 Aug 2.

Department of Biostatistics, Genentech Inc., South San Francisco, California 94080, USA.

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http://dx.doi.org/10.1136/jclinpath-2012-200911DOI Listing
November 2012

Neuropilin-2 expression in cancer.

Histopathology 2012 Sep 2;61(3):340-9. Epub 2012 Mar 2.

Department of Pathology, Genentech Inc., South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.1111/j.1365-2559.2012.04224.xDOI Listing
September 2012

Expression of vascular Notch ligands Delta-like 4 and Jagged-1 in glioblastoma.

Histopathology 2012 Apr 1;60(5):740-7. Epub 2012 Feb 1.

Nuffield Department of Clinical Laboratory Sciences, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1111/j.1365-2559.2011.04138.xDOI Listing
April 2012

Neuropilin-1 expression in cancer and development.

J Pathol 2012 Jan 25;226(1):50-60. Epub 2011 Oct 25.

Department of Pathology, Genentech Inc, South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.1002/path.2989DOI Listing
January 2012

Ascl2 and 11p15.5 amplification in colorectal cancer.

Gut 2011 Nov 23;60(11):1606-7; author reply 1607. Epub 2010 Nov 23.

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http://dx.doi.org/10.1136/gut.2010.231746DOI Listing
November 2011

p21-activated kinase 1: PAK'ed with potential.

Oncotarget 2011 Jun;2(6):491-6

Department of Translational Oncology, Genentech, Inc., South San Francisco, CA 94080, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248206PMC
http://dx.doi.org/10.18632/oncotarget.271DOI Listing
June 2011

Biomarkers to predict the clinical efficacy of bevacizumab in cancer.

Lancet Oncol 2010 Dec;11(12):1172-83

Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1016/S1470-2045(10)70232-1DOI Listing
December 2010

The histone demethylase JMJD2B is regulated by estrogen receptor alpha and hypoxia, and is a key mediator of estrogen induced growth.

Cancer Res 2010 Aug 3;70(16):6456-66. Epub 2010 Aug 3.

Growth Factor Group, Cancer Research UK, Molecular Oncology Laboratories, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Headington, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-0413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261152PMC
August 2010

Targeting DLL4 in tumors shows preclinical activity but potentially significant toxicity.

Future Oncol 2010 Jul;6(7):1099-103

Cancer Research UK Molecular Oncology Laboratories, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK.

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http://dx.doi.org/10.2217/fon.10.62DOI Listing
July 2010

Phase I dose-escalation study of recombinant human Apo2L/TRAIL, a dual proapoptotic receptor agonist, in patients with advanced cancer.

J Clin Oncol 2010 Jun 10;28(17):2839-46. Epub 2010 May 10.

University of Texas M D Anderson Cancer Center, Thoracic Head and Neck Medicine Clinic, 1515 Holcombe Blvd, Unit 432, Houston, TX 77030, USA.

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http://dx.doi.org/10.1200/JCO.2009.25.1991DOI Listing
June 2010

Expression of vascular notch ligand delta-like 4 and inflammatory markers in breast cancer.

Am J Pathol 2010 Apr 18;176(4):2019-28. Epub 2010 Feb 18.

Nuffield Department of Clinical Laboratory Sciences,Weatherall Institute ofMolecular Medicine, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.2353/ajpath.2010.090908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843489PMC
April 2010

Assessment of tumour hypoxia for prediction of response to therapy and cancer prognosis.

J Cell Mol Med 2010 Jan 16;14(1-2):18-29. Epub 2009 Oct 16.

Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.

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http://doi.wiley.com/10.1111/j.1582-4934.2009.00944.x
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http://dx.doi.org/10.1111/j.1582-4934.2009.00944.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837600PMC
January 2010

Biomarkers and response to therapy in breast cancer.

Authors:
Adrian M Jubb

Clin Cancer Res 2009 Jan;15(1):414; author reply 414-5

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http://dx.doi.org/10.1158/1078-0432.CCR-08-2404DOI Listing
January 2009

Predicting benefit from anti-angiogenic agents in malignancy.

Nat Rev Cancer 2006 Aug 13;6(8):626-35. Epub 2006 Jul 13.

Academic Unit of Pathology, Leeds Institute for Molecular Medicine, University of Leeds, UK.

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http://www.nature.com/articles/nrc1946
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http://dx.doi.org/10.1038/nrc1946DOI Listing
August 2006

Quantitative in situ hybridization of tissue microarrays.

Methods Mol Biol 2006 ;326:255-64

Academic Unit of Pathology, University of Leeds, UK.

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http://link.springer.com/10.1385/1-59745-007-3:255
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http://dx.doi.org/10.1385/1-59745-007-3:255DOI Listing
July 2006

EphB2 is a prognostic factor in colorectal cancer.

Clin Cancer Res 2005 Jul;11(14):5181-7

Department of Pathology, Genentech, Inc., South San Francisco, California 94080, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-05-0143DOI Listing
July 2005

DNA methylation, a biomarker for colorectal cancer: implications for screening and pathological utility.

Ann N Y Acad Sci 2003 Mar;983:251-67

Academic Unit of Pathology, Leeds University, Leeds, UK.

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http://dx.doi.org/10.1111/j.1749-6632.2003.tb05980.xDOI Listing
March 2003