Publications by authors named "Adrian G Sacher"

24Publications

Cytotoxic CD4 T Cells in Bladder Cancer-A New License to Kill.

Cancer Cell 2020 Jul;38(1):28-30

Princess Margaret Cancer Centre, University Health Network, 610 University Ave., Toronto, ON M5G 2M9, Canada; Department of Immunology, Faculty of Medicine, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2020.06.013DOI Listing
July 2020

EGFR-mutated lung adenocarcinomas from patients who progressed on EGFR-inhibitors show high engraftment rates in xenograft models.

Lung Cancer 2020 07 11;145:144-151. Epub 2020 May 11.

University Health Network, Ontario Cancer Institute/Princess Margaret Cancer Centre, Toronto, Ontario, Canada; Departments of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; Division of Medical Oncology and Hematology, Department of Medicine, Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada; Dalla Lana School of Public Health and Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2020.03.022DOI Listing
July 2020

Next-generation sequencing informs diagnosis and identifies unexpected therapeutic targets in lung squamous cell carcinomas.

Lung Cancer 2020 02 16;140:35-41. Epub 2019 Dec 16.

Department of Pathology, Brigham and Women's Hospital, 75 Francis St, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.lungcan.2019.12.005DOI Listing
February 2020

Monitoring of Response and Resistance in Plasma of EGFR-Mutant Lung Cancer Using Droplet Digital PCR.

Methods Mol Biol 2018 ;1768:193-207

Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, MA, USA.

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http://dx.doi.org/10.1007/978-1-4939-7778-9_12DOI Listing
February 2019

PD-L1 expression in non-small cell lung carcinoma: Comparison among cytology, small biopsy, and surgical resection specimens.

Cancer Cytopathol 2017 Dec 12;125(12):896-907. Epub 2017 Oct 12.

Department of Pathology and Cell Biology, New York-Presbyterian Hospital/Columbia University Irving Medical Center, New York, New York.

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http://dx.doi.org/10.1002/cncy.21937DOI Listing
December 2017

Circulating Tumor DNA as a Liquid Biopsy: Current Clinical Applications and Future Directions.

Oncology (Williston Park) 2017 08;31(8):618-27

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August 2017

Application of Plasma Genotyping Technologies in Non-Small Cell Lung Cancer: A Practical Review.

J Thorac Oncol 2017 09 10;12(9):1344-1356. Epub 2017 Jun 10.

Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts; Brigham and Women's Hospital, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts.

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https://linkinghub.elsevier.com/retrieve/pii/S15560864173044
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http://dx.doi.org/10.1016/j.jtho.2017.05.022DOI Listing
September 2017

Co-clinical quantitative tumor volume imaging in ALK-rearranged NSCLC treated with crizotinib.

Eur J Radiol 2017 Mar 26;88:15-20. Epub 2016 Dec 26.

Department of Medical Oncology and Department of Medicine Dana-Farber Cancer Institute and Brigham and Women's Hospital 450 Brookline Ave., Boston MA, 02215, USA.

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http://dx.doi.org/10.1016/j.ejrad.2016.12.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560072PMC
March 2017

The promise and pitfalls of the many methods of plasma genotyping.

Expert Opin Biol Ther 2016 Nov 12;16(11):1313-1316. Epub 2016 Sep 12.

a Division of Hematology/Oncology , Columbia University Medical Center/New York-Presbyterian Hospital , New York , NY , USA.

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http://dx.doi.org/10.1080/14712598.2016.1229769DOI Listing
November 2016

Early Intervention in Lung Cancers With Rapid Plasma Genotyping for EGFR and KRAS Mutations-Reply.

JAMA Oncol 2016 08;2(8):1096-7

Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts2Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamaoncol.2016.1963DOI Listing
August 2016

Biomarkers for the Clinical Use of PD-1/PD-L1 Inhibitors in Non-Small-Cell Lung Cancer: A Review.

JAMA Oncol 2016 Sep;2(9):1217-22

Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts3Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamaoncol.2016.0639DOI Listing
September 2016

Prospective Validation of Rapid Plasma Genotyping for the Detection of EGFR and KRAS Mutations in Advanced Lung Cancer.

JAMA Oncol 2016 Aug;2(8):1014-22

Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts2Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamaoncol.2016.0173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982795PMC
August 2016

Association Between Younger Age and Targetable Genomic Alterations and Prognosis in Non-Small-Cell Lung Cancer.

JAMA Oncol 2016 Mar;2(3):313-20

Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts2Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamaoncol.2015.4482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819418PMC
March 2016

Real-world chemotherapy treatment patterns in metastatic non-small cell lung cancer: Are patients undertreated?

Cancer 2015 Aug 17;121(15):2562-9. Epub 2015 Apr 17.

Division of Medical Oncology, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.

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http://doi.wiley.com/10.1002/cncr.29386
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http://dx.doi.org/10.1002/cncr.29386DOI Listing
August 2015

Management of acquired resistance to epidermal growth factor receptor kinase inhibitors in patients with advanced non-small cell lung cancer.

Cancer 2014 Aug 17;120(15):2289-98. Epub 2014 Apr 17.

Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts; Princess Margaret Cancer Center, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/cncr.28723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117471PMC
August 2014

Shifting patterns in the interpretation of phase III clinical trial outcomes in advanced non-small-cell lung cancer: the bar is dropping.

J Clin Oncol 2014 May 3;32(14):1407-11. Epub 2014 Mar 3.

All authors: Princess Margaret Cancer Centre/University Health Network, University of Toronto, Toronto, Ontario, Canada.

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http://ascopubs.org/doi/10.1200/JCO.2013.52.7804
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http://dx.doi.org/10.1200/JCO.2013.52.7804DOI Listing
May 2014

Fulvestrant for advanced breast cancer: a meta-analysis.

Cancer Treat Rev 2013 Nov 10;39(7):753-8. Epub 2013 Jun 10.

Division of Medical Oncology and Hematology, Princess Margaret Hospital, Toronto, Canada.

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http://dx.doi.org/10.1016/j.ctrv.2013.03.004DOI Listing
November 2013

Elderly patients with advanced NSCLC in phase III clinical trials: are the elderly excluded from practice-changing trials in advanced NSCLC?

J Thorac Oncol 2013 Mar;8(3):366-8

Division of Medical Oncology & Hematology, Princess Margaret Hospital & University Health Network, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/JTO.0b013e31827e2145DOI Listing
March 2013

Taking the stress out of morning report: an analytic approach to the differential diagnosis.

J Gen Intern Med 2009 Jun 31;24(6):747-51. Epub 2009 Mar 31.

Department of Medicine, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1007/s11606-009-0953-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686763PMC
June 2009

New drugs for brain tumors? Insights from chemical probing of neural stem cells.

Med Hypotheses 2009 Jun 3;72(6):683-7. Epub 2009 Mar 3.

The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children and University of Toronto, 555 University Avenue, Toronto, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S03069877090006
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http://dx.doi.org/10.1016/j.mehy.2008.10.034DOI Listing
June 2009

Chemical genetics reveals a complex functional ground state of neural stem cells.

Nat Chem Biol 2007 May 8;3(5):268-73. Epub 2007 Apr 8.

The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children and University of Toronto, 555 University Avenue, Toronto M5G 1X8, Canada.

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http://dx.doi.org/10.1038/nchembio873DOI Listing
May 2007