Adrian Bot

Adrian Bot

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Adrian Bot

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Safety and feasibility of anti-CD19 CAR T cells with fully human binding domains in patients with B-cell lymphoma.

Nat Med 2020 Feb 20;26(2):270-280. Epub 2020 Jan 20.

Experimental Transplantation and Immunotherapy Branch, Center for Cancer Research, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA.

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http://dx.doi.org/10.1038/s41591-019-0737-3DOI Listing
February 2020

Melanoma-associated antigen-A and programmed death-ligand 1 expression are associated with advanced urothelial carcinoma.

Cancer Immunol Immunother 2019 May 21;68(5):743-751. Epub 2019 Feb 21.

Department of Urology, Institute of Urologic Oncology, David Geffen School of Medicine at University of California, 300 Stein Plaza, Suite 348, Los Angeles, CA, 90095, USA.

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http://link.springer.com/10.1007/s00262-019-02316-w
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http://dx.doi.org/10.1007/s00262-019-02316-wDOI Listing
May 2019

In this issue: Antibodies and T Cell subtypes in diseases and therapy.

Int Rev Immunol 2018 ;37(4):175-176

b International Reviews of Immunology, Translational Sciences , Kite Pharma Inc. , Santa Monica , CA , USA.

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https://www.tandfonline.com/doi/full/10.1080/08830185.2018.1
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http://dx.doi.org/10.1080/08830185.2018.1499488DOI Listing
April 2019

Axicabtagene ciloleucel, a first-in-class CAR T cell therapy for aggressive NHL.

Leuk Lymphoma 2018 08 23;59(8):1785-1796. Epub 2017 Oct 23.

b Department of Medicine , University of California at Los Angeles Jonsson Comprehensive Cancer Center , Los Angeles , CA , USA.

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http://dx.doi.org/10.1080/10428194.2017.1387905DOI Listing
August 2018

In this issue: Role of immune cells and molecules in rheumatoid arthritis pathogenesis and cancer immunotherapy.

Int Rev Immunol 2018 05;37(3):127-128

b International Reviews of Immunology and Vice President, Translational Sciences , Kite Pharma Inc. , Santa Monica , CA , USA.

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http://dx.doi.org/10.1080/08830185.2018.1469353DOI Listing
May 2018

In this issue: Effect of gut microbiome on mucosal immunity and enteric diseases.

Int Rev Immunol 2018 03;37(2):77-78

b Editor in Chief, International Reviews of Immunology and Vice President , Translational Sciences, Kite Pharma Inc. , Santa Monica , CA , USA.

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http://dx.doi.org/10.1080/08830185.2018.1450947DOI Listing
March 2018

In this issue: Role of specific and non-specific immunity in disease.

Int Rev Immunol 2018 01;37(1):1-2

b Editor in Chief, International Reviews of Immunology and Vice President, Translational Sciences, Kite Pharma Inc. , Santa Monica , CA , USA.

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http://dx.doi.org/10.1080/08830185.2018.1432192DOI Listing
January 2018

Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma.

N Engl J Med 2017 12 10;377(26):2531-2544. Epub 2017 Dec 10.

From the University of Texas M.D. Anderson Cancer Center, Houston (S.S.N., J.R.W.); H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL (F.L.L., J.C.C.); Washington University and Siteman Cancer Center, St. Louis (N.L.B., A. Ghobadi); University of Miami, Miami (L.J.L., K.V.K.); Stanford University, Stanford (D.B.M., R.L.), City of Hope National Medical Center, Duarte (T.S.), University of California at Los Angeles, Los Angeles (J.M.T.), University of California at San Diego, San Diego (J.E.C.), and Kite Pharma, Santa Monica (A.B., J.R., L.N., Y.J., J.A., M.E., D.C., J.W., W.Y.G.) - all in California; Dana-Farber Cancer Institute, Boston (C.A.J., E.D.J.); Montefiore Medical Center, Bronx (I.B.), and the University of Rochester School of Medicine, Rochester (J.W.F., P.R.) - both in New York; Vanderbilt University Medical Center (O.O.O.) and the Sarah Cannon Research Institute and Tennessee Oncology (I.W.F.), Nashville; Mayo Clinic, Rochester, MN (Y.L., T.E.W.); Loyola University Medical Center, Maywood, IL (P.J.S.); John Theurer Cancer Center, Hackensack University Medical Center, Hackensack, NJ (A. Goy); Cleveland Clinic, Cleveland (B.T.H., M.R.S.); Karmanos Cancer Center, Wayne State University, Detroit (A.D.); University of Iowa Carver College of Medicine, Iowa City (U.F.); Colorado Blood Cancer Institute, Denver (P.M.S.); Banner M.D. Anderson Cancer Center, Gilbert, AZ (J.M.); and Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (I.A.).

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http://dx.doi.org/10.1056/NEJMoa1707447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882485PMC
December 2017

In this issue: Cancer immunity and immunotherapy.

Int Rev Immunol 2017 11;36(6):313-314

b Editor in Chief, International Reviews of Immunology and Vice President , Translational Sciences, Kite Pharma Inc. , Santa Monica , CA , USA.

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http://dx.doi.org/10.1080/08830185.2017.1398539DOI Listing
November 2017

In this issue: Fine tuners of immunity and their role in infectious and non-infectious diseases.

Int Rev Immunol 2017 09;36(5):257-258

b Editor in Chief, International Reviews of Immunology and Vice President, Translational Sciences , Kite Pharma Inc. , Santa Monica , CA , USA.

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http://dx.doi.org/10.1080/08830185.2017.1399712DOI Listing
September 2017

In this issue: Role of immune cells, immune modulating factors and immunotoxins in cancer immunotherapy.

Int Rev Immunol 2017 07 24;36(4):205-206. Epub 2017 May 24.

b Editor in Chief, International Reviews of Immunology and Vice President, Translational Sciences , Kite Pharma Inc. , Santa Monica , California , USA.

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http://dx.doi.org/10.1080/08830185.2017.1326784DOI Listing
July 2017

Lymphoma Remissions Caused by Anti-CD19 Chimeric Antigen Receptor T Cells Are Associated With High Serum Interleukin-15 Levels.

J Clin Oncol 2017 Jun 14;35(16):1803-1813. Epub 2017 Mar 14.

James N. Kochenderfer, Robert P.T. Somerville, Tangying Lu, Victoria Shi, Stephanie L. Goff, James C. Yang, Richard M. Sherry, Christopher A. Klebanoff, Udai S. Kammula, Constance M. Yuan, Mark J. Roschewski, Steven A. Feldman, Lori McIntyre, Mary Ann Toomey, and Steven A. Rosenberg, National Cancer Institute, National Institutes of Health, Bethesda, MD; Adrian Bot, John Rossi, Allen Xue, Marika Sherman, and Arianne Perez, Kite Pharma, Santa Monica, CA; Tatyana Feldman, John Theurer Cancer Center, Hackensack University Medical Center, Hackensack, NJ; and Jonathan W. Friedberg, University of Rochester School of Medicine, Rochester, NY.

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http://ascopubs.org/doi/10.1200/JCO.2016.71.3024
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http://dx.doi.org/10.1200/JCO.2016.71.3024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455597PMC
June 2017

Role of MicroRNAs in shaping innate immunity and as therapeutic targets for autoimmune diseases.

Int Rev Immunol 2017 05 10;36(3):123-124. Epub 2017 Jul 10.

b International Reviews of Immunology and Vice President, Translational Sciences , Kite Pharma Inc. , Editor in Chief, Santa Monica , California , USA.

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http://dx.doi.org/10.1080/08830185.2017.1340043DOI Listing
May 2017

In this issue: Innate immunity and infectious diseases-An update.

Int Rev Immunol 2017 03 23;36(2):55-56. Epub 2017 Mar 23.

b Editor in Chief, International Reviews of Immunology and Vice President , Translational Sciences, Kite Pharma Inc. , Santa Monica , California , USA.

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http://dx.doi.org/10.1080/08830185.2017.1307021DOI Listing
March 2017

In this issue: Antibodies in pathogenesis and management of diseases.

Int Rev Immunol 2017 01;36(1):1-2

b Editor in Chief, International Reviews of Immunology and Vice President, Translational Sciences , Kite Pharma Inc. , Santa Monica , California , USA.

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http://dx.doi.org/10.1080/08830185.2017.1290936DOI Listing
January 2017

Constantin A. Bona, M.D., Ph.D.

Int Rev Immunol 2016 ;35(1):1-3

f MolecularMicrobiology and Immunology , University of Missouri , Columbia , MO , USA.

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http://dx.doi.org/10.3109/08830185.2016.1139991DOI Listing
December 2016

In This Issue: Molecular, Genetic and Cellular Aspects Related to Primary and Acquired Immunodeficiencies.

Authors:
Adrian Bot

Int Rev Immunol 2016 ;35(1):4-6

a Editor in Chief, International Reviews of Immunology and Vice President, Translational Sciences , Kite Pharma Inc.

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http://dx.doi.org/10.3109/08830185.2016.1139993DOI Listing
December 2016

In This Issue: On Biology of Dendritic Cells and B Cells.

Authors:
Adrian Bot

Int Rev Immunol 2016 ;35(2):83-4

a Editor in Chief, International Reviews of Immunology and Vice President, Translational Sciences, Kite Pharma Inc.

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http://dx.doi.org/10.3109/08830185.2016.1156390DOI Listing
December 2016

In This Issue: Protein Structure, Cellular Metabolism, and Genetics in Immunity.

Int Rev Immunol 2016 11;35(6):455-456

b Editor in Chief, International Reviews of Immunology and Vice President, Translational Sciences, Kite Pharma Inc. , Santa Monica , California , USA.

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http://dx.doi.org/10.1080/08830185.2016.1258904DOI Listing
November 2016

In This Issue: Cellular and Molecular Mechanisms Orchestrating the Innate Immunity During Infectious and Non-infectious Disease.

Int Rev Immunol 2016 09;35(5):369-371

b Editor in Chief, International Reviews of Immunology and Vice President, Translational Sciences, Kite Pharma Inc., Santa Monica , California , USA.

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http://dx.doi.org/10.1080/08830185.2016.1258903DOI Listing
September 2016

In this issue: advances in molecular pathology of inflammatory disorders.

Authors:
Adrian Bot

Int Rev Immunol 2015 ;34(6):i-ii

a International Reviews of Immunology and Vice President , Translational Sciences, Kite Pharma Inc.

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http://dx.doi.org/10.3109/08830185.2015.1104119DOI Listing
August 2016

In This Issue: Translational Opportunities for Antibodies: Therapeutics, Biomarkers, and Novel Targets.

Int Rev Immunol 2016 07;35(4):291-293

b Associate Editor-in-Chief, International Reviews of Immunology, Associate Professor, Laboratory of Immunology and Infectious Disease Biology, Indian Institute of Science Education and Research (IISER) , Bhopal , India.

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http://dx.doi.org/10.1080/08830185.2016.1236584DOI Listing
July 2016

In This Issue: The Multiple Facets of IL-17.

Int Rev Immunol 2015 ;34(4):293-4

Editor in Chief, International Reviews of Immunology; and Kite Pharma Inc , Santa Monica , CA.

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http://dx.doi.org/10.3109/08830185.2015.1052289DOI Listing
June 2016

In This Issue: At the Interaction between the Immune System and Microbes.

Authors:
Adrian Bot

Int Rev Immunol 2016 05;35(3):177-8

a International Reviews of Immunology Vice President, Translational Sciences , Kite Pharma Inc.

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http://dx.doi.org/10.1080/08830185.2016.1185868DOI Listing
May 2016

Editorial--in this issue: innate immunity in normal and pathologic circumstances.

Authors:
Adrian Bot

Int Rev Immunol 2014 Nov-Dec;33(6):441-2

Editor in Chief, International Reviews of Immunology.

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http://dx.doi.org/10.3109/08830185.2014.978699DOI Listing
July 2015

Editorial: in this issue.

Authors:
Adrian Bot

Int Rev Immunol 2015 May;34(3):201

International Reviews of Immunology, and Kite Pharma, Inc , Santa Monica, CA , USA.

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http://dx.doi.org/10.3109/08830185.2015.1041855DOI Listing
May 2015

A new era in cancer immunotherapy: discovering novel targets and reprogramming the immune system.

Int Rev Immunol 2015 Mar;34(2):101-3

Section Editor, International Reviews of Immunology and Kiromic LLC , Lubbock, TX , USA.

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http://dx.doi.org/10.3109/08830185.2015.1015888DOI Listing
March 2015

Low-complexity PDE-based approach for automatic microarray image processing.

Med Biol Eng Comput 2015 Feb 29;53(2):99-110. Epub 2014 Oct 29.

Department of Mass Spectrometry, Chromatography and Applied Physics, National Institute for Research and Development of Isotopic and Molecular Technologies, Cluj-Napoca, Romania,

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http://dx.doi.org/10.1007/s11517-014-1214-2DOI Listing
February 2015

Metabolism of immune cells.

Int Rev Immunol 2015 Jan;34(1):1-2

1Guest and Section Editor, International Reviews of Immunology, and Pfizer Inc.

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http://dx.doi.org/10.3109/08830185.2015.1003462DOI Listing
January 2015

Editorial: international reviews of immunology.

Int Rev Immunol 2014 Oct;33(5):365-6

1Kiromic LLC, 6104 45th St., Lubbock, TX.

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http://dx.doi.org/10.3109/08830185.2014.941239DOI Listing
October 2014

The Th17 cell population and the immune homeostasis of the gastrointestinal tract.

Int Rev Immunol 2013 Oct-Dec;32(5-6):471-4

Section Editor, International Reviews of Immunology, Senior Researcher Institute of Food Sciences , CNR, Avellino , Italy.

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http://dx.doi.org/10.3109/08830185.2013.843983DOI Listing
June 2014

In this issue: autoimmunity and innate immunity.

Authors:
Adrian Bot

Int Rev Immunol 2014 Jan;33(1):1-2

Editor-in-Chief, International Reviews of Immunology, Vice President, Scientific Affairs, Kite Pharma, Inc., Santa Monica, CA, USA.

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http://dx.doi.org/10.3109/08830185.2014.877705DOI Listing
January 2014

Repositioning therapeutic cancer vaccines in the dawning era of potent immune interventions.

Expert Rev Vaccines 2013 Oct 8;12(10):1219-34. Epub 2013 Oct 8.

Kite Pharma Inc., Santa Monica, CA, USA.

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http://dx.doi.org/10.1586/14760584.2013.836908DOI Listing
October 2013

In this issue: from basic immunology to oncogenesis and inflammation.

Authors:
Adrian Bot

Int Rev Immunol 2013 Jun 24;32(3):221-2. Epub 2013 May 24.

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http://dx.doi.org/10.3109/08830185.2013.802135DOI Listing
June 2013

Innate immune recognition mechanisms and translational opportunities.

Int Rev Immunol 2013 Apr;32(2):113-5

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http://dx.doi.org/10.3109/08830185.2013.775803DOI Listing
April 2013

In this issue of the International Reviews of Immunology.

Authors:
Adrian Bot

Int Rev Immunol 2012 Jun;31(3):175-6

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http://dx.doi.org/10.3109/08830185.2012.688718DOI Listing
June 2012

In this issue: Tec kinases in the crosshairs.

Int Rev Immunol 2012 Apr;31(2):85-6

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http://dx.doi.org/10.3109/08830185.2012.671692DOI Listing
April 2012

The 2011 Nobel Prize--honoring the memory of Dr. Ralph Steinman.

Int Rev Immunol 2011 Oct-Dec;30(5-6):233-4

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http://dx.doi.org/10.3109/08830185.2011.630972DOI Listing
March 2012

In this issue--engineering the immune system to fight cancer and infections.

Authors:
Adrian Bot

Int Rev Immunol 2011 Oct-Dec;30(5-6):235-7

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http://dx.doi.org/10.3109/08830185.2011.626714DOI Listing
March 2012

Cancer vaccines at an inflexion point: what next?

J Transl Med 2011 Sep 9;9:148. Epub 2011 Sep 9.

Kite Pharma, Inc., Los Angeles CA 90024, USA.

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http://dx.doi.org/10.1186/1479-5876-9-148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175186PMC
September 2011

International Reviews of Immunology. Editorial: in this issue.

Authors:
Adrian Bot

Int Rev Immunol 2010 ;29(1):1-3

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http://dx.doi.org/10.3109/08830180903519688DOI Listing
April 2010

TLR-9 signaling and TCR stimulation co-regulate CD8(+) T cell-associated PD-1 expression.

Immunol Lett 2009 Dec 12;127(1):60-7. Epub 2009 Sep 12.

MannKind Corporation, 28903 Avenue Paine, Valencia, CA, USA.

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http://dx.doi.org/10.1016/j.imlet.2009.09.002DOI Listing
December 2009

In this issue: new topics in miRNA and transplantation immunology.

Int Rev Immunol 2009 ;28(3-4):109-11

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http://dx.doi.org/10.1080/08830180902990620DOI Listing
December 2009

In this issue: shifting the focus to modern vaccinology.

Authors:
Adrian Bot

Int Rev Immunol 2009 ;28(1):1-3

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http://dx.doi.org/10.1080/08830180902721033DOI Listing
April 2009

In this issue: shifting the focus to modern vaccinology.

Authors:
Adrian Bot

Int Rev Immunol 2008 ;27(6):389-91

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http://dx.doi.org/10.1080/08830180802550870DOI Listing
March 2009

In this issue: basic immunology and translational research on NF-kappaB.

Authors:
Adrian Bot

Int Rev Immunol 2008 ;27(5):283-5

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http://dx.doi.org/10.1080/08830180802319797DOI Listing
January 2009

International reviews of immunology: expanding the scope and content.

Int Rev Immunol 2008 ;27(4):177-82

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http://dx.doi.org/10.1080/08830180802148378DOI Listing
August 2008

Antigen kinetics determines immune reactivity.

Proc Natl Acad Sci U S A 2008 Apr 24;105(13):5189-94. Epub 2008 Mar 24.

Unit Experimental Immunotherapy, Department of Dermatology, University Hospital Zurich, Gloriastrasse 31, CH-8091 Zurich, Switzerland.

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http://dx.doi.org/10.1073/pnas.0706296105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2278203PMC
April 2008

Editorial.

Authors:
Adrian Bot

Int Rev Immunol 2005 Sep-Dec;24(5-6):285-6

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http://dx.doi.org/10.1080/08830180500369847DOI Listing
February 2006

Recombinant immunoglobulin-based epitope delivery: a novel class of autoimmune regulators.

Int Rev Immunol 2005 Sep-Dec;24(5-6):501-17

MultiCell Immunotherapeutics, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1080/08830180500379648DOI Listing
February 2006

Heat denaturation, a simple method to improve the immunotherapeutic potential of allergens.

Eur J Immunol 2005 Dec;35(12):3591-8

Unit for Experimental Immunotherapy, University Hospital of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1002/eji.200535076DOI Listing
December 2005

Molecular and cellular control of T1/T2 immunity at the interface between antimicrobial defense and immune pathology.

DNA Cell Biol 2004 Jun;23(6):341-50

Department of Immunology and Cancer Research, MannKind Corporation, Valencia, California, USA.

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http://dx.doi.org/10.1089/104454904323145227DOI Listing
June 2004

Rational design of solid aerosols for immunoglobulin delivery by modulation of aerodynamic and release characteristics.

J Control Release 2004 Mar;95(3):489-500

Department of Immunology, Alliance Pharmaceutical Corp. San Diego, CA 92121, USA.

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http://dx.doi.org/10.1016/j.jconrel.2003.12.013DOI Listing
March 2004

Evaluation of novel aerosol formulations designed for mucosal vaccination against influenza virus.

Vaccine 2003 Jun;21(21-22):2805-12

Department of Immunology, Alliance Pharmaceutical Corp., San Diego, CA, USA.

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http://dx.doi.org/10.1016/s0264-410x(03)00224-xDOI Listing
June 2003

Immune responsiveness, tolerance and dsRNA: implications for traditional paradigms.

Trends Immunol 2003 Jun;24(6):289-93

Division of Developmental Immunology, La Jolla Institute for Allergy and Immunology, 10355 Science Center Drive, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1016/s1471-4906(03)00121-2DOI Listing
June 2003

Antigen-based immune modulation: DNA vectors and beyond.

Expert Opin Biol Ther 2002 Dec;2(8):929-42

AlleCure Corporation, 28903 North Avenue Paine, Valencia, CA 91355, USA.

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http://dx.doi.org/10.1517/14712598.2.8.929DOI Listing
December 2002

Noncoding RNA danger motifs bridge innate and adaptive immunity and are potent adjuvants for vaccination.

J Clin Invest 2002 Oct;110(8):1175-84

Department of Immunology, Astral Inc. of Alliance Pharmaceutical Corporation, 3040 Science Park Road, San Diego, California 92121, USA.

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http://dx.doi.org/10.1172/JCI15536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC150792PMC
October 2002

Genetic immunization of neonates.

Microbes Infect 2002 Apr;4(4):511-20

Department of Immunology, Alliance Pharmaceutical Corp., 6175 Lusk Blvd, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1016/s1286-4579(02)01566-6DOI Listing
April 2002