Publications by authors named "Adnan M Nagrial"

23Publications

The Evolving Understanding of the Molecular and Therapeutic Landscape of Pancreatic Ductal Adenocarcinoma.

Diseases 2018 Nov 13;6(4). Epub 2018 Nov 13.

The Kinghorn Cancer Centre, The Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, Sydney, NSW 2010, Australia.

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http://dx.doi.org/10.3390/diseases6040103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313363PMC
November 2018

Metastatic pancreatic ductal adenocarcinoma: diagnosis and treatment with a view to the future.

Intern Med J 2018 06;48(6):637-644

Department of Medical Oncology, The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.

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http://dx.doi.org/10.1111/imj.13810DOI Listing
June 2018

Corrigendum: Whole-genome landscape of pancreatic neuroendocrine tumours.

Authors:
Aldo Scarpa David K Chang Katia Nones Vincenzo Corbo Ann-Marie Patch Peter Bailey Rita T Lawlor Amber L Johns David K Miller Andrea Mafficini Borislav Rusev Maria Scardoni Davide Antonello Stefano Barbi Katarzyna O Sikora Sara Cingarlini Caterina Vicentini Skye McKay Michael C J Quinn Timothy J C Bruxner Angelika N Christ Ivon Harliwong Senel Idrisoglu Suzanne McLean Craig Nourse Ehsan Nourbakhsh Peter J Wilson Matthew J Anderson J Lynn Fink Felicity Newell Nick Waddell Oliver Holmes Stephen H Kazakoff Conrad Leonard Scott Wood Qinying Xu Shivashankar Hiriyur Nagaraj Eliana Amato Irene Dalai Samantha Bersani Ivana Cataldo Angelo P Dei Tos Paola Capelli Maria Vittoria Davì Luca Landoni Anna Malpaga Marco Miotto Vicki L J Whitehall Barbara A Leggett Janelle L Harris Jonathan Harris Marc D Jones Jeremy Humphris Lorraine A Chantrill Venessa Chin Adnan M Nagrial Marina Pajic Christopher J Scarlett Andreia Pinho Ilse Rooman Christopher Toon Jianmin Wu Mark Pinese Mark Cowley Andrew Barbour Amanda Mawson Emily S Humphrey Emily K Colvin Angela Chou Jessica A Lovell Nigel B Jamieson Fraser Duthie Marie-Claude Gingras William E Fisher Rebecca A Dagg Loretta M S Lau Michael Lee Hilda A Pickett Roger R Reddel Jaswinder S Samra James G Kench Neil D Merrett Krishna Epari Nam Q Nguyen Nikolajs Zeps Massimo Falconi Michele Simbolo Giovanni Butturini George Van Buren Stefano Partelli Matteo Fassan Kum Kum Khanna Anthony J Gill David A Wheeler Richard A Gibbs Elizabeth A Musgrove Claudio Bassi Giampaolo Tortora Paolo Pederzoli John V Pearson Nicola Waddell Andrew V Biankin Sean M Grimmond

Nature 2017 10 27;550(7677):548. Epub 2017 Sep 27.

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http://dx.doi.org/10.1038/nature24026DOI Listing
October 2017

Whole-genome landscape of pancreatic neuroendocrine tumours.

Authors:
Aldo Scarpa David K Chang Katia Nones Vincenzo Corbo Ann-Marie Patch Peter Bailey Rita T Lawlor Amber L Johns David K Miller Andrea Mafficini Borislav Rusev Maria Scardoni Davide Antonello Stefano Barbi Katarzyna O Sikora Sara Cingarlini Caterina Vicentini Skye McKay Michael C J Quinn Timothy J C Bruxner Angelika N Christ Ivon Harliwong Senel Idrisoglu Suzanne McLean Craig Nourse Ehsan Nourbakhsh Peter J Wilson Matthew J Anderson J Lynn Fink Felicity Newell Nick Waddell Oliver Holmes Stephen H Kazakoff Conrad Leonard Scott Wood Qinying Xu Shivashankar Hiriyur Nagaraj Eliana Amato Irene Dalai Samantha Bersani Ivana Cataldo Angelo P Dei Tos Paola Capelli Maria Vittoria Davì Luca Landoni Anna Malpaga Marco Miotto Vicki L J Whitehall Barbara A Leggett Janelle L Harris Jonathan Harris Marc D Jones Jeremy Humphris Lorraine A Chantrill Venessa Chin Adnan M Nagrial Marina Pajic Christopher J Scarlett Andreia Pinho Ilse Rooman Christopher Toon Jianmin Wu Mark Pinese Mark Cowley Andrew Barbour Amanda Mawson Emily S Humphrey Emily K Colvin Angela Chou Jessica A Lovell Nigel B Jamieson Fraser Duthie Marie-Claude Gingras William E Fisher Rebecca A Dagg Loretta M S Lau Michael Lee Hilda A Pickett Roger R Reddel Jaswinder S Samra James G Kench Neil D Merrett Krishna Epari Nam Q Nguyen Nikolajs Zeps Massimo Falconi Michele Simbolo Giovanni Butturini George Van Buren Stefano Partelli Matteo Fassan Kum Kum Khanna Anthony J Gill David A Wheeler Richard A Gibbs Elizabeth A Musgrove Claudio Bassi Giampaolo Tortora Paolo Pederzoli John V Pearson Nicola Waddell Andrew V Biankin Sean M Grimmond

Nature 2017 03 15;543(7643):65-71. Epub 2017 Feb 15.

University of Melbourne Centre for Cancer Research, University of Melbourne, Melbourne, 3010, Victoria, Australia.

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http://dx.doi.org/10.1038/nature21063DOI Listing
March 2017

Hypermutation In Pancreatic Cancer.

Gastroenterology 2017 01 15;152(1):68-74.e2. Epub 2016 Nov 15.

Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom; Department of Surgery, Bankstown Hospital, Bankstown, Sydney, New South Wales, Australia; South Western Sydney Clinical School, Faculty of Medicine, University of New South Wales Australia, Liverpool, New South Wales, Australia; West of Scotland Pancreatic Unit, Glasgow Royal Infirmary, Glasgow, United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00165085163518
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http://dx.doi.org/10.1053/j.gastro.2016.09.060DOI Listing
January 2017

Resolution of Novel Pancreatic Ductal Adenocarcinoma Subtypes by Global Phosphotyrosine Profiling.

Mol Cell Proteomics 2016 08 3;15(8):2671-85. Epub 2016 Jun 3.

¶Cancer Program, Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Level 1, Building 77, Monash University, VIC 3800, Australia;

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http://dx.doi.org/10.1074/mcp.M116.058313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974343PMC
August 2016

Genomic analyses identify molecular subtypes of pancreatic cancer.

Authors:
Peter Bailey David K Chang Katia Nones Amber L Johns Ann-Marie Patch Marie-Claude Gingras David K Miller Angelika N Christ Tim J C Bruxner Michael C Quinn Craig Nourse L Charles Murtaugh Ivon Harliwong Senel Idrisoglu Suzanne Manning Ehsan Nourbakhsh Shivangi Wani Lynn Fink Oliver Holmes Venessa Chin Matthew J Anderson Stephen Kazakoff Conrad Leonard Felicity Newell Nick Waddell Scott Wood Qinying Xu Peter J Wilson Nicole Cloonan Karin S Kassahn Darrin Taylor Kelly Quek Alan Robertson Lorena Pantano Laura Mincarelli Luis N Sanchez Lisa Evers Jianmin Wu Mark Pinese Mark J Cowley Marc D Jones Emily K Colvin Adnan M Nagrial Emily S Humphrey Lorraine A Chantrill Amanda Mawson Jeremy Humphris Angela Chou Marina Pajic Christopher J Scarlett Andreia V Pinho Marc Giry-Laterriere Ilse Rooman Jaswinder S Samra James G Kench Jessica A Lovell Neil D Merrett Christopher W Toon Krishna Epari Nam Q Nguyen Andrew Barbour Nikolajs Zeps Kim Moran-Jones Nigel B Jamieson Janet S Graham Fraser Duthie Karin Oien Jane Hair Robert Grützmann Anirban Maitra Christine A Iacobuzio-Donahue Christopher L Wolfgang Richard A Morgan Rita T Lawlor Vincenzo Corbo Claudio Bassi Borislav Rusev Paola Capelli Roberto Salvia Giampaolo Tortora Debabrata Mukhopadhyay Gloria M Petersen Donna M Munzy William E Fisher Saadia A Karim James R Eshleman Ralph H Hruban Christian Pilarsky Jennifer P Morton Owen J Sansom Aldo Scarpa Elizabeth A Musgrove Ulla-Maja Hagbo Bailey Oliver Hofmann Robert L Sutherland David A Wheeler Anthony J Gill Richard A Gibbs John V Pearson Nicola Waddell Andrew V Biankin Sean M Grimmond

Nature 2016 Mar 24;531(7592):47-52. Epub 2016 Feb 24.

Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia.

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http://dx.doi.org/10.1038/nature16965DOI Listing
March 2016

Rho-associated kinase signalling and the cancer microenvironment: novel biological implications and therapeutic opportunities.

Expert Rev Mol Med 2015 Oct 28;17:e17. Epub 2015 Oct 28.

The Kinghorn Cancer Centre,Cancer Division,Garvan Institute of Medical Research,384 Victoria St,Darlinghurst,Sydney,NSW 2010,Australia.

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http://dx.doi.org/10.1017/erm.2015.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836205PMC
October 2015

Second-line treatment in inoperable pancreatic adenocarcinoma: A systematic review and synthesis of all clinical trials.

Crit Rev Oncol Hematol 2015 Dec 26;96(3):483-97. Epub 2015 Jul 26.

Department of Medical Oncology, The Canberra Hospital, Garran, ACT, Australia; ANU Medical School, Australian National University, Acton, ACT, Australia.

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http://dx.doi.org/10.1016/j.critrevonc.2015.07.007DOI Listing
December 2015

Precision Medicine for Advanced Pancreas Cancer: The Individualized Molecular Pancreatic Cancer Therapy (IMPaCT) Trial.

Clin Cancer Res 2015 May;21(9):2029-37

The Kinghorn Cancer Centre, Cancer Division, Garvan Institute of Medical Research, Sydney, New South Wales, Australia. Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, Scotland. Department of Surgery, Bankstown Hospital, Sydney, New South Wales, Australia. South Western Sydney Clinical School, Faculty of Medicine, University of NSW, Liverpool, New South Wales, Australia. West of Scotland Pancreatic Unit, Glasgow Royal Infirmary, Glasgow, United Kingdom.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-0426DOI Listing
May 2015

Whole genomes redefine the mutational landscape of pancreatic cancer.

Nature 2015 Feb;518(7540):495-501

1] Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia [2] Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK.

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http://dx.doi.org/10.1038/nature14169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523082PMC
February 2015

Preexisting MEK1P124 mutations diminish response to BRAF inhibitors in metastatic melanoma patients.

Clin Cancer Res 2015 Jan 4;21(1):98-105. Epub 2014 Nov 4.

Westmead Institute for Cancer Research, University of Sydney at Westmead Millennium Institute, Westmead, New South Wales, Australia. Australian School of Advanced Medicine, Macquarie University, New South Wales, Australia. Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-0759DOI Listing
January 2015

Clinical and pathologic features of familial pancreatic cancer.

Cancer 2014 Dec 14;120(23):3669-75. Epub 2014 Oct 14.

The Kinghorn Cancer Center, Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia.

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http://dx.doi.org/10.1002/cncr.28863DOI Listing
December 2014

Gemcitabine and CHK1 inhibition potentiate EGFR-directed radioimmunotherapy against pancreatic ductal adenocarcinoma.

Clin Cancer Res 2014 Jun 16;20(12):3187-97. Epub 2014 May 16.

Authors' Affiliations: Signal Transduction Laboratory, QIMR Berghofer Medical Research Institute, Herston; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland; The Kinghorn Cancer Centre, Cancer Division, Garvan Institute of Medical Research; St Vincent's Clinical School, Faculty of Medicine, University of NSW; Department of Anatomical Pathology, SYDPATH, St Vincent's Hospital, Darlinghurst, New South Wales; Australian Pancreatic Cancer Genome Initiative, for the full list of contributors see http://www.pancreaticcancer.net.au/apgi/collaborators; Cancer Clinical Trials Unit, Royal Adelaide Hospital Cancer Centre, and Centre for Cancer Biology, SA Pathology; School of Medicine, University of Adelaide, Adelaide, Australia; and Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, Scotland, United KingdomAuthors' Affiliations: Signal Transduction Laboratory, QIMR Berghofer Medical Research Institute, Herston; Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland; The Kinghorn Cancer Centre, Cancer Division, Garvan Institute of Medical Research; St Vincent's Clinical School, Faculty of Medicine, University of NSW; Department of Anatomical Pathology, SYDPATH, St Vincent's Hospital, Darlinghurst, New South Wales; Australian Pancreatic Cancer Genome Initiative, for the full list of contributors see http://www.pancreaticcancer.net.au/apgi/collaborators; Cancer Clinical Trials Unit, Royal Adelaide Hospital Cancer Centre, and Centre for Cancer Biology, SA Pathology; School of Medicine, University of Adelaide, Adelaide, Australia; and Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom.

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http://clincancerres.aacrjournals.org/content/early/2014/05/
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http://clincancerres.aacrjournals.org/content/early/2014/05/
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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-14-0048DOI Listing
June 2014

New RAS-mutant pancreatic adenocarcinoma with combined BRAF and MEK inhibition for metastatic melanoma.

J Clin Oncol 2015 Apr 12;33(11):e52-6. Epub 2014 May 12.

Melanoma Institute Australia; The University of Sydney and Westmead Institute for Cancer Research, Sydney, Australia

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http://dx.doi.org/10.1200/JCO.2013.51.5783DOI Listing
April 2015

Clinical and molecular characterization of HER2 amplified-pancreatic cancer.

Genome Med 2013 31;5(8):78. Epub 2013 Aug 31.

Kinghorn Cancer Centre and Garvan Institute of Medical Research, Darlinghurst, Sydney, Australia ; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK ; West of Scotland Pancreatic Unit, Glasgow Royal Infirmary, Glasgow, UK.

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http://dx.doi.org/10.1186/gm482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978667PMC
May 2014

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes.

Authors:
Andrew V Biankin Nicola Waddell Karin S Kassahn Marie-Claude Gingras Lakshmi B Muthuswamy Amber L Johns David K Miller Peter J Wilson Ann-Marie Patch Jianmin Wu David K Chang Mark J Cowley Brooke B Gardiner Sarah Song Ivon Harliwong Senel Idrisoglu Craig Nourse Ehsan Nourbakhsh Suzanne Manning Shivangi Wani Milena Gongora Marina Pajic Christopher J Scarlett Anthony J Gill Andreia V Pinho Ilse Rooman Matthew Anderson Oliver Holmes Conrad Leonard Darrin Taylor Scott Wood Qinying Xu Katia Nones J Lynn Fink Angelika Christ Tim Bruxner Nicole Cloonan Gabriel Kolle Felicity Newell Mark Pinese R Scott Mead Jeremy L Humphris Warren Kaplan Marc D Jones Emily K Colvin Adnan M Nagrial Emily S Humphrey Angela Chou Venessa T Chin Lorraine A Chantrill Amanda Mawson Jaswinder S Samra James G Kench Jessica A Lovell Roger J Daly Neil D Merrett Christopher Toon Krishna Epari Nam Q Nguyen Andrew Barbour Nikolajs Zeps Nipun Kakkar Fengmei Zhao Yuan Qing Wu Min Wang Donna M Muzny William E Fisher F Charles Brunicardi Sally E Hodges Jeffrey G Reid Jennifer Drummond Kyle Chang Yi Han Lora R Lewis Huyen Dinh Christian J Buhay Timothy Beck Lee Timms Michelle Sam Kimberly Begley Andrew Brown Deepa Pai Ami Panchal Nicholas Buchner Richard De Borja Robert E Denroche Christina K Yung Stefano Serra Nicole Onetto Debabrata Mukhopadhyay Ming-Sound Tsao Patricia A Shaw Gloria M Petersen Steven Gallinger Ralph H Hruban Anirban Maitra Christine A Iacobuzio-Donahue Richard D Schulick Christopher L Wolfgang Richard A Morgan Rita T Lawlor Paola Capelli Vincenzo Corbo Maria Scardoni Giampaolo Tortora Margaret A Tempero Karen M Mann Nancy A Jenkins Pedro A Perez-Mancera David J Adams David A Largaespada Lodewyk F A Wessels Alistair G Rust Lincoln D Stein David A Tuveson Neal G Copeland Elizabeth A Musgrove Aldo Scarpa James R Eshleman Thomas J Hudson Robert L Sutherland David A Wheeler John V Pearson John D McPherson Richard A Gibbs Sean M Grimmond

Nature 2012 Nov 24;491(7424):399-405. Epub 2012 Oct 24.

The Kinghorn Cancer Centre, 370 Victoria Street, Darlinghurst, Sydney, New South Wales 2010, Australia.

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http://dx.doi.org/10.1038/nature11547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530898PMC
November 2012

Prognostic and clinicopathologic associations of oncogenic BRAF in metastatic melanoma.

J Clin Oncol 2011 Apr 22;29(10):1239-46. Epub 2011 Feb 22.

Melanoma Institute Australia, 40 Rocklands Rd, North Sydney, New South Wales, 2060, Australia.

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http://dx.doi.org/10.1200/JCO.2010.32.4327DOI Listing
April 2011