Dr Adnan Khurshid, PhD - National Institute of Health - Virologist

Dr Adnan Khurshid

PhD

National Institute of Health

Virologist

Islamabad, Pakistan | Pakistan

Main Specialties: Biology, Epidemiology, Infectious Disease

Additional Specialties: Molecular epidemiology

ORCID logohttps://orcid.org/0000-0002-8780-6992

Dr Adnan Khurshid, PhD - National Institute of Health - Virologist

Dr Adnan Khurshid

PhD

Introduction

Primary Affiliation: National Institute of Health - Islamabad, Pakistan , Pakistan

Specialties:

Additional Specialties:

Research Interests:


View Dr Adnan Khurshid’s Resume / CV

Education

Aug 2018
Hazara University Mansehra KP Pakistan
PhD

Experience

Jan 2009
Virologist WHO RRL for PEI NIH Islamabad
Laboratory Scientist

Publications

29Publications

461Reads

412Profile Views

84PubMed Central Citations

Surveillance of Crimean-Congo haemorrhagic fever in Pakistan.

2017 Aug;17(8):806.

Lancet Infect Dis.

Crimean-Congo haemorrhagic fever (CCHF) is a tick-borne viral disease that has been reported across Asia, Africa, eastern Europe, the Balkans, and the Middle East. In Pakistan, the first case of CCHF was documented in 1976 and its prevalence has been vigorously debated since.1 Findings from some studies have associated the incidence of CCHF in Pakistan with the coinciding event of Eidul-Adha, when tens of millions of animals are sacrificed every year.1,2 Although epidemiological evidence3 suggests that animal movement during Eid-ul-Adha might facilitate the transmission of CCHF virus, the extent of the facilitation is not well known. We plotted the time of Eidul-Adha against the onset date of cases of CCHF confirmed by real-time PCR assay at the National Institute of Health (NIH), Islamabad, Pakistan (appendix). Our analysis, based on 1339 suspected cases, 302 (23%) of which were laboratory confirmed, during January 2011 to March 2017, did not show a direct association between the occurrence of CCHF cases and the time of Eid-ul-Adha, thus rebuking the earlier notions. In fact, the exceedingly abundant prevalence of hyalomma ticks in Pakistan, largely during the summer months, is well documented,4 thus substantiating our findings that the CCHF cases in Pakistan might appear independently of Eid-ul-Adha, and their occurrence has coincided with the peak season of tick proliferation during the preceding 8–10 years. Previous reports1,2 have attributed the enhanced CCHF spread to the movement of animals from Balochistan, but no concrete evidence is available ratifying this explanation as the sole contributor to sporadic CCHF cases outside Balochistan. In support, we refer to our findings5–7 that the CCHFV virus strains are endemic and strictly restricted within Balochistan where cases continue to be reported throughout the year with incidental spillovers elsewhere in the country. These findings are further reinforced by our data showing 99–100% genetic relatedness among the CCHF viral strains detected in Balochistan over decades,6 thus signifying that Balochistan might have an isolated and dispersed population of CCHF-virus hosts and a vector that might sustain and amplify the disease primarily within the province. NIH-Pakistan is the focal point for International Health Regulations and the country’s only reference public health laboratory, providing freeof-cost diagnostic services for many high-priority diseases including CCHF. Nevertheless, there is a dire need to enhance coordination between animal and human sectors through integrated disease surveillance to foster preparedness and effective prevention and control. We declare no competing interests. *Muhammad Masroor Alam, Adnan Khurshid, Muhammad Suleman Rana, Uzma Bashir Aamir, Muhammad Salman, Mukhtar Ahmad ursmasroor@yahoo.com Department of Virology, National Institute of Health, Chak Shahzad, Islamabad, Pakistan (MMA, AK, MSR, UBA, MS, MA) 1 Karim AM, Hussain I, Lee JH, Park KS, Lee SH. Surveillance of Crimean-Congo haemorrhagic fever in Pakistan. Lancet Infect Dis 2017; 17: 367–68. 2 Mallhi TH, Khan YH, Sarriff A, Khan AH. Crimean-Congo haemorrhagic fever virus and Eid-Ul-Adha festival in Pakistan. Lancet Infect Dis 2016; 16: 1332–33. 3 Al-Abri SS, Abaidani IA, Fazlalipour M, et al. Current status of Crimean-Congo haemorrhagic fever in the World Health Organization Eastern Mediterranean Region: issues, challenges, and future directions. Int J Infect Dis 2017; 58: 82–89. 4 Sajid MS, Iqbal Z, Khan MN, Muhammad G. Point prevalence of hard ticks (Ixodids) infesting domestic ruminants of lower Punjab, Pakistan. Int J Agri Biol 2008; 10: 349–51. 5 Alam MM, Kurshid A, Sharif S, et al. Crimean-Congo hemorrhagic fever Asia-2 genotype, Pakistan. Emerg Infect Dis 2013; 19: 1017–19. 6 Alam MM, Khurshid A, Sharif S, et al. Genetic analysis and epidemiology of Crimean Congo hemorrhagic fever viruses in Baluchistan province of Pakistan. BMC Infect Dis 2013; 13: 201. 7 Khurshid A, Hassan M, Alam MM, et al. CCHF virus variants in Pakistan and Afghanistan: Emerging diversity and epidemiology. J Clin Virol 2015; 67: 25–30.

View Article
August 2017
1 Read

Molecular characterization of echovirus 13 uncovering high genetic diversity and identification of new genotypes in Pakistan.

Infect Genet Evol 2017 03 20;48:102-108. Epub 2016 Dec 20.

Department of Virology, National Institute of Health, Chak Shahzad, Park Road, Islamabad 45500, Pakistan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.meegid.2016.12.017DOI Listing
March 2017
8 Reads
3.020 Impact Factor

Dengue Virus Serotypes Circulating in Khyber Pakhtunkhwa Province, Pakistan, 2013-2015.

Ann Lab Med 2017 Mar;37(2):151-154

Department of Virology, National Institute of Health, Park Road, Chak Shahzad, Islamabad, Pakistan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3343/alm.2017.37.2.151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5203993PMC
March 2017
10 Reads
2 Citations
1.481 Impact Factor

NS1 antigen: A new beam of light in the early diagnosis of dengue infection.

Asian Pac J Trop Med 2016 12 9;9(12):1212-1214. Epub 2016 Nov 9.

Department of Virology, National Institute of Health, Park Road, Chak Shahzad, Islamabad, Pakistan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.apjtm.2016.10.007DOI Listing
December 2016
15 Reads
0.930 Impact Factor

Dengue outbreak in Swat and Mansehra, Pakistan 2013: An epidemiological and diagnostic perspective.

Asian Pac J Trop Med 2016 Apr 9;9(4):380-384. Epub 2016 Mar 9.

Department of Virology, National Institute of Health, Park Road, Chak Shahzad, Islamabad, Pakistan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.apjtm.2016.03.010DOI Listing
April 2016
13 Reads
4 Citations
0.930 Impact Factor

Genomic Surveillance Elucidates Persistent Wild Poliovirus Transmission During 2013-2015 in Major Reservoir Areas of Pakistan.

Clin Infect Dis 2016 Jan 28;62(2):190-198. Epub 2015 Sep 28.

Department of Virology, National Institute of Health, Chak Shahzad, Islamabad, Pakistan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/cid/civ831DOI Listing
January 2016
8 Reads
4 Citations
8.890 Impact Factor

Identification of new genotype of Echovirus 19 from children with Acute Flaccid Paralysis in Pakistan.

Sci Rep 2015 Dec 8;5:17456. Epub 2015 Dec 8.

Department of Virology, National Institute of Health, Chak Shahzad, Park Road, Islamabad-45500, Pakistan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep17456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672337PMC
December 2015
9 Reads
1 Citation
5.080 Impact Factor

CCHF virus variants in Pakistan and Afghanistan: Emerging diversity and epidemiology.

J Clin Virol 2015 Jun 28;67:25-30. Epub 2015 Mar 28.

Department of Virology, National Institute of Health, Islamabad, Pakistan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jcv.2015.03.021DOI Listing
June 2015
16 Reads
2 Citations
3.020 Impact Factor

'Human bocavirus in Pakistani children with gastroenteritis'.

J Med Virol 2015 Apr 21;87(4):656-63. Epub 2015 Jan 21.

Department of Virology, National Institute of Health, Islamabad, Pakistan; Department of Biotechnology, Quaid-i-Azam University, Islamabad, Pakistan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jmv.24090DOI Listing
April 2015
20 Reads
5 Citations
2.350 Impact Factor

Viral etiologies of acute dehydrating gastroenteritis in pakistani children: confounding role of parechoviruses.

Viruses 2015 Jan 20;7(1):378-93. Epub 2015 Jan 20.

Department of Virology, National Institute of Health, Chak Shahzad, Park Road, Islamabad 44000, Pakistan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/v7010378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306844PMC
January 2015
17 Reads
3.280 Impact Factor

Molecular epidemiology of enterovirus B77 isolated from non polio acute flaccid paralytic patients in Pakistan during 2013.

Infect Genet Evol 2015 Jan 26;29:189-95. Epub 2014 Nov 26.

Department of Virology, National Institute of Health, Chak Shahzad, Park Road, Islamabad 45500, Pakistan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.meegid.2014.11.021DOI Listing
January 2015
17 Reads
3 Citations
3.020 Impact Factor

Detection of multiple cocirculating wild poliovirus type 1 lineages through environmental surveillance: impact and progress during 2011-2013 in Pakistan.

J Infect Dis 2014 Nov;210 Suppl 1:S324-32

WHO Regional Reference Laboratory for Polio Eradication Initiative, Department of Virology, National Institute of Health, Chak Shahzad, Islamabad, Pakistan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/infdis/jiu160DOI Listing
November 2014
19 Reads
6 Citations
6.000 Impact Factor

Characterization of a novel enterovirus serotype and an enterovirus EV-B93 isolated from acute flaccid paralysis patients.

PLoS One 2013 7;8(11):e80040. Epub 2013 Nov 7.

Department of Virology, National Institute of Health, Chak Shahzad, Islamabad, Pakistan ; Department of Biotechnology, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0080040PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820551PMC
August 2014
21 Reads
3 Citations
3.234 Impact Factor

Serotype diversity of astroviruses in Rawalpindi, Pakistan during 2009-2010.

PLoS One 2013 18;8(4):e61667. Epub 2013 Apr 18.

Department of Biotechnology, Quaid-i-Azam University, Islamabad, Pakistan.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0061667PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630178PMC
December 2013
17 Reads
2 Citations
3.234 Impact Factor

Genetic analysis and epidemiology of Crimean Congo Hemorrhagic fever viruses in Baluchistan province of Pakistan.

BMC Infect Dis 2013 May 4;13:201. Epub 2013 May 4.

Department of Virology, National Institute of Health, Chak Shahzad, Park Road, Islamabad, 44000, Pakistan.

View Article

Download full-text PDF

Source
http://bmcinfectdis.biomedcentral.com/articles/10.1186/1471-
Publisher Site
http://dx.doi.org/10.1186/1471-2334-13-201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652740PMC
May 2013
15 Reads
3 Citations
2.613 Impact Factor

Characterization of non-polio enterovirus isolates from acute flaccid paralysis children in Pakistan reflects a new genotype of EV-107.

Virus Res 2012 Dec 2;170(1-2):164-8. Epub 2012 Oct 2.

Department of Virology, National Institute of Health, Islamabad, Pakistan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.virusres.2012.09.010DOI Listing
December 2012
8 Reads
3 Citations
2.324 Impact Factor

Identification of human parechovirus genotype, HPeV-12, in a paralytic child with diarrhea.

J Clin Virol 2012 Dec 11;55(4):339-42. Epub 2012 Sep 11.

Department of Biotechnology, Quaid-i-Azam University, Islamabad, Pakistan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jcv.2012.08.008DOI Listing
December 2012
5 Reads
6 Citations
3.020 Impact Factor

Molecular identification and characterization of a new type of bovine enterovirus.

Appl Environ Microbiol 2012 Jun 6;78(12):4497-500. Epub 2012 Apr 6.

Department of Virology, National Institute of Health, Islamabad, Pakistan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AEM.00109-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370518PMC
June 2012
6 Reads
5 Citations
3.670 Impact Factor

Genetic relationships and epidemiological links between wild type 1 poliovirus isolates in Pakistan and Afghanistan.

Virol J 2012 Feb 22;9:51. Epub 2012 Feb 22.

Virology Department, National Institute of Health Park Road, Chak Shahzad, Islamabad 45500, Pakistan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1743-422X-9-51DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307474PMC
February 2012
58 Reads
4 Citations
2.181 Impact Factor

Genetic characterization of rotavirus subtypes in Pakistan-first report of G12 genotype from Pakistan under WHO-Eastern Mediterranean region.

Virus Res 2009 Sep 5;144(1-2):280-4. Epub 2009 Apr 5.

Department of Virology, National Institute of Health, Chak Shahzad, Park Road, Islamabad 54400, Pakistan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.virusres.2009.03.015DOI Listing
September 2009
23 Reads
3 Citations
2.324 Impact Factor