Adele K Fielding

Adele K Fielding

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Adele K Fielding

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ARF way to Ph ALL stratification?

Authors:
Adele K Fielding

Blood 2018 03;131(13):1394-1395

UCL Cancer Institute.

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http://dx.doi.org/10.1182/blood-2018-02-829085DOI Listing
March 2018

Complete Hematologic and Molecular Response in Adult Patients With Relapsed/Refractory Philadelphia Chromosome-Positive B-Precursor Acute Lymphoblastic Leukemia Following Treatment With Blinatumomab: Results From a Phase II, Single-Arm, Multicenter Study.

J Clin Oncol 2017 Jun 29;35(16):1795-1802. Epub 2017 Mar 29.

Giovanni Martinelli and Cristina Papayannidis, Institute of Hematology and Medical Oncology "L. and A. Seràgnoli", Bologna; Alessandro Rambaldi, University of Milan Hematology and Bone Marrow Transplant Unit, Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy; Nicolas Boissel, University Paris Diderot, Hôpital Saint-Louis, Paris; Patrice Chevallier, Centre Hospitalier Universitaire Nantes, Nantes, France; Oliver Ottmann, Cardiff University, Cardiff; Adele K. Fielding, University College London Cancer Institute, London, United Kingdom; Nicola Gökbuget, University Hospital, Goethe University, Frankfurt; Max S. Topp, Universitätsklinikum Würzburg, Würzburg, Germany; Ellen K. Ritchie, Weill Cornell Medical College and New York Presbyterian Hospital, New York, NY; Lulu Ren Sterling, Amgen, San Francisco; Jonathan Benjamin, Amgen, Thousand Oaks; and Anthony Stein, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA.

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http://dx.doi.org/10.1200/JCO.2016.69.3531DOI Listing
June 2017

Characterisation of the genomic landscape of CRLF2-rearranged acute lymphoblastic leukemia.

Genes Chromosomes Cancer 2017 05 18;56(5):363-372. Epub 2017 Jan 18.

Leukaemia Research Cytogenetics Group, Northern Institute for Cancer Research, Newcastle University, Newcastle-upon-Tyne, UK.

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http://dx.doi.org/10.1002/gcc.22439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5396319PMC
May 2017

Blinatumomab versus Chemotherapy for Advanced Acute Lymphoblastic Leukemia.

N Engl J Med 2017 03;376(9):836-847

From the Department of Leukemia, University of Texas M.D. Anderson Cancer Center, Houston (H.K.); City of Hope National Medical Center, Duarte (A.S.), and Amgen, Thousand Oaks (A.F., D.N., Z.Z.) - both in California; Goethe University, University Hospital, Department of Medicine II, Frankfurt am Main (N.G.), Medical Department II (H.-A.H., M.B.) and Hematopathology Section and Lymph Node Registry (W.K.), University Hospital Schleswig Holstein, Campus Kiel, Kiel, and Medizinische Klinik und Poliklinik II, Universitätsklinikums Würzburg, Würzburg (M.S.T.) - all in Germany; Royal Free Hospital and University College London Cancer Institute, London (A.K.F.); Princess Margaret Cancer Centre, Toronto (A.C.S.), and Centre Intégré Universitaire de Santé et de Services Sociaux de l'est de l'île de Montréal, Hôpital Maisonneuve-Rosemont, Montreal (J.B.) - all in Canada; ICO-Hospital Universitari Germans Trias i Pujol, Jose Carreras Research Institute, Universitat Autonoma de Barcelona, Barcelona (J.-M.R.), the Department of Medicine, Hospital Universitari i Politecnic La Fe, University of Valencia, Valencia, and Centro de Investigación Biomédica en Red de Cáncer, Instituto Carlos III, Madrid (M.A.S.) - all in Spain; Alfred Hospital and Monash University, Melbourne, VIC, Australia (A.W.); Institut Universitaire d'Hématologie, Hôpital Saint-Louis (Assistance Publique - Hôpitaux de Paris), Paris (H.D.), and Centre Hospitalier Lyon Sud, Pierre-Benite (X.T.) - both in France; Ematologia, Dipartimento di Biotecnologie Cellulari ed Ematologia, Azienda Ospedaliera Policlinico Umberto I, Università Sapienza di Roma, Rome (R.F.), Azienda Unità Locale Socio Sanitaria 12 Veneziana Ospedale Dell Angelo, Venice (R.B.), and Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, Università Statale di Milano, Milan (A.R.) - all in Italy; Ankara Universitesi, Tip Fakültesi, Cebeci Arastirma ve Uygulama Hastanesi, Ankara (Ö.A.), and Dokuz Eylül Üniversitesi Tıp Fakültesi, İzmir (F.D.) - both in Turkey; Instytut Hematologii i Transfuzjologii and Centrum Medyczne Kształcenia Podyplomowego, Warsaw, Poland (E.L.-M.); University of Washington Medical Center, Seattle (B.L.W.); and Amgen, Washington, DC (C.H.).

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http://dx.doi.org/10.1056/NEJMoa1609783DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881572PMC
March 2017

Impact of Pretransplantation (18)F-Fluorodeoxyglucose-Positron Emission Tomography on Survival Outcomes after T Cell-Depleted Allogeneic Transplantation for Hodgkin Lymphoma.

Biol Blood Marrow Transplant 2016 07 14;22(7):1234-1241. Epub 2016 Apr 14.

Department of Haematology, University College London Hospitals NHS Trust, London, United Kingdom; Department of Haematology, University College London Cancer Institute, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2016.03.034DOI Listing
July 2016

Treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia in adults: a broader range of options, improved outcomes, and more therapeutic dilemmas.

Authors:
Adele K Fielding

Am Soc Clin Oncol Educ Book 2015 :e352-9

From the UCL Cancer Institute, London, United Kingdom.

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http://dx.doi.org/10.14694/EdBook_AM.2015.35.e352DOI Listing
February 2016

IGH@ translocations are prevalent in teenagers and young adults with acute lymphoblastic leukemia and are associated with a poor outcome.

J Clin Oncol 2014 May 7;32(14):1453-62. Epub 2014 Apr 7.

Lisa J. Russell, Amir Enshaei, Lisa Jones, Amy Erhorn, Dino Masic, Helen Bentley, Anthony V. Moorman, and Christine J. Harrison, Leukaemia Research Cytogenetics Group, Northern Institute for Cancer Research, Newcastle University, Newcastle-upon-Tyne; Karl S. Laczko, Leica Microsystems, Gateshead; Adele K. Fielding, Royal Free and University College London Medical School; Anthony H. Goldstone, University College London Hospital; Nicholas Goulden, Great Ormond St Hospital, London; Christopher D. Mitchell, John Radcliffe Hospital; Rachel Wade, Clinical Trial Service Unit, University of Oxford, Oxford; and Ajay Vora, Sheffield Children's Hospital, Sheffield, United Kingdom.

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http://dx.doi.org/10.1200/JCO.2013.51.3242DOI Listing
May 2014

IGH@ translocations, CRLF2 deregulation, and microdeletions in adolescents and adults with acute lymphoblastic leukemia.

J Clin Oncol 2012 Sep 30;30(25):3100-8. Epub 2012 Jul 30.

Leukaemia Research Cytogenetics Group, Northern Institute for Cancer Research, Level 5, Sir James Spence Institute, Royal Victoria Infirmary, Queen Victoria Rd, Newcastle-upon-Tyne, NE1 4LP, United Kingdom.

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http://dx.doi.org/10.1200/JCO.2011.40.3907DOI Listing
September 2012

Emerging pharmacotherapies for adult patients with acute lymphoblastic leukemia.

Clin Med Insights Oncol 2012 22;6:85-100. Epub 2012 Jan 22.

Department of Hematology, Hillingdon Hospital, Pield Heath Road, Uxbridge, Middlesex, UB8 3NN.

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http://dx.doi.org/10.4137/CMO.S7262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273927PMC
August 2012

Recent developments in the management of T-cell precursor acute lymphoblastic leukemia/lymphoma.

Curr Hematol Malig Rep 2012 Jun;7(2):160-9

Department of Hematology, University College London, Royal Free Campus, London, UK.

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http://link.springer.com/10.1007/s11899-012-0123-4
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http://dx.doi.org/10.1007/s11899-012-0123-4DOI Listing
June 2012

Current treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia.

Authors:
Adele K Fielding

Hematology Am Soc Hematol Educ Program 2011 ;2011:231-7

University College London, London, United Kingdom.

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http://www.asheducationbook.org/cgi/doi/10.1182/asheducation
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http://dx.doi.org/10.1182/asheducation-2011.1.231DOI Listing
April 2012

Attenuated, oncolytic, but not wild-type measles virus infection has pleiotropic effects on human neutrophil function.

J Immunol 2012 Feb 16;188(3):1002-10. Epub 2011 Dec 16.

Department of Haematology, University College London, London, United Kingdom.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1102262
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http://dx.doi.org/10.4049/jimmunol.1102262DOI Listing
February 2012

Current therapeutic strategies in adult acute lymphoblastic leukemia.

Authors:
Adele K Fielding

Hematol Oncol Clin North Am 2011 Dec;25(6):1255-79, viii

UK National Cancer Research Institute (NCRI) Adult ALL Subgroup, University College London, Royal Free Campus, Rowland Hill Street, London NW3 2PF, UK.

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http://dx.doi.org/10.1016/j.hoc.2011.09.008DOI Listing
December 2011

Philadelphia-positive acute lymphoblastic leukemia--is bone marrow transplant still necessary?

Authors:
Adele K Fielding

Biol Blood Marrow Transplant 2011 Jan;17(1 Suppl):S84-8

Department of Haematology, University College London, Royal Free Campus, London, United Kingdom.

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http://dx.doi.org/10.1016/j.bbmt.2010.11.023DOI Listing
January 2011

How I treat Philadelphia chromosome-positive acute lymphoblastic leukemia.

Authors:
Adele K Fielding

Blood 2010 Nov 23;116(18):3409-17. Epub 2010 Jul 23.

University College London, Royal Free Campus, Rowland Hill Street, London, United Kingdom.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2010-01-24
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http://dx.doi.org/10.1182/blood-2010-01-242750DOI Listing
November 2010

The treatment of adults with acute lymphoblastic leukemia.

Hematology Am Soc Hematol Educ Program 2008 :381-9

Royal Free and University College Medical School, London, UK.

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http://www.asheducationbook.org/cgi/doi/10.1182/asheducation
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http://dx.doi.org/10.1182/asheducation-2008.1.381DOI Listing
July 2009

Outcome of 609 adults after relapse of acute lymphoblastic leukemia (ALL); an MRC UKALL12/ECOG 2993 study.

Blood 2007 Feb 10;109(3):944-50. Epub 2006 Oct 10.

Royal Free and University College London Medical School, and Christie Hospital National Health Service Trust, Manchester, UK.

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http://dx.doi.org/10.1182/blood-2006-05-018192DOI Listing
February 2007

Measles as a potential oncolytic virus.

Authors:
Adele K Fielding

Rev Med Virol 2005 Mar-Apr;15(2):135-42

Department of Haematology, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, UK.

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http://dx.doi.org/10.1002/rmv.455DOI Listing
April 2005

Neutrophils contribute to the measles virus-induced antitumor effect: enhancement by granulocyte macrophage colony-stimulating factor expression.

Cancer Res 2003 Oct;63(19):6463-8

Molecular Medicine Program, Mayo Clinic, Rochester, MN 55905, USA.

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October 2003

Lack of specificity of cell-surface protease targeting of a cytotoxic hyperfusogenic gibbon ape leukaemia virus envelope glycoprotein.

J Gene Med 2002 Nov-Dec;4(6):592-600

Molecular Medicine Program, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

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http://doi.wiley.com/10.1002/jgm.306
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http://dx.doi.org/10.1002/jgm.306DOI Listing
May 2003

An oncolytic measles virus engineered to enter cells through the CD20 antigen.

Mol Ther 2003 Jan;7(1):62-72

Mayo Clinic Molecular Medicine Program, 200 First Street SW, Rochester, Minnesota 55902, USA.

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http://dx.doi.org/10.1016/s1525-0016(02)00033-3DOI Listing
January 2003