Publications by authors named "Adam T Waickman"

26Publications

The Cytokine Receptor IL-7Rα Impairs IL-2 Receptor Signaling and Constrains the In Vitro Differentiation of Foxp3 Treg Cells.

iScience 2020 Aug 29;23(8):101421. Epub 2020 Jul 29.

Experimental Immunology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, NIH, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2020.101421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424196PMC
August 2020

IL7 receptor signaling in T cells: A mathematical modeling perspective.

Wiley Interdiscip Rev Syst Biol Med 2019 09 28;11(5):e1447. Epub 2019 May 28.

Department of Applied Mathematics, School of Mathematics, University of Leeds, Leeds, UK.

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http://dx.doi.org/10.1002/wsbm.1447DOI Listing
September 2019

RORγt limits the amount of the cytokine receptor γc through the prosurvival factor Bcl-x in developing thymocytes.

Sci Signal 2018 08 28;11(545). Epub 2018 Aug 28.

Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1126/scisignal.aam8939DOI Listing
August 2018

CD4 effector T cell differentiation is controlled by IL-15 that is expressed and presented in trans.

Cytokine 2017 11 12;99:266-274. Epub 2017 Aug 12.

Experimental Immunology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2017.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675755PMC
November 2017

Distinct IL-7 signaling in recent thymic emigrants versus mature naïve T cells controls T-cell homeostasis.

Eur J Immunol 2016 07 17;46(7):1669-80. Epub 2016 May 17.

Experimental Transplantation and Immunology Branch, Bethesda, MD, USA.

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http://dx.doi.org/10.1002/eji.201546214DOI Listing
July 2016

Asymmetric inheritance of mTORC1 kinase activity during division dictates CD8(+) T cell differentiation.

Nat Immunol 2016 06 11;17(6):704-11. Epub 2016 Apr 11.

Sidney-Kimmel Comprehensive Cancer Research Center, Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1038/ni.3438DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873361PMC
June 2016

The common γ-chain cytokine receptor: tricks-and-treats for T cells.

Cell Mol Life Sci 2016 Jan 14;73(2):253-69. Epub 2015 Oct 14.

Experimental Immunology Branch, National Cancer Institute, National Institutes of Health (NIH), Bldg. 10, Room 5B17, 10 Center Dr, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1007/s00018-015-2062-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315299PMC
January 2016

Cellular size as a means of tracking mTOR activity and cell fate of CD4+ T cells upon antigen recognition.

PLoS One 2015 7;10(4):e0121710. Epub 2015 Apr 7.

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0121710PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388710PMC
March 2016

The transcription factor ThPOK suppresses Runx3 and imposes CD4(+) lineage fate by inducing the SOCS suppressors of cytokine signaling.

Nat Immunol 2014 Jul 1;15(7):638-45. Epub 2014 Jun 1.

Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.

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http://www.nature.com/articles/ni.2917
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http://dx.doi.org/10.1038/ni.2917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693509PMC
July 2014

A modified model of T-cell differentiation based on mTOR activity and metabolism.

Cold Spring Harb Symp Quant Biol 2013 7;78:125-30. Epub 2013 Oct 7.

Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231.

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http://dx.doi.org/10.1101/sqb.2013.78.020214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979500PMC
March 2015

Macrophage A2A adenosinergic receptor modulates oxygen-induced augmentation of murine lung injury.

Am J Respir Cell Mol Biol 2013 May;48(5):635-46

Division of Pulmonary and Critical Care Medicine, Johns Hopkins Asthma and Allergy Center, School of Medicine, Johns Hopkins University, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1165/rcmb.2012-0351OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707379PMC
May 2013

CD73 is critical for the resolution of murine colonic inflammation.

J Biomed Biotechnol 2012 14;2012:260983. Epub 2012 Oct 14.

Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.

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http://dx.doi.org/10.1155/2012/260983DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477584PMC
April 2013

mTOR, metabolism, and the regulation of T-cell differentiation and function.

Immunol Rev 2012 Sep;249(1):43-58

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1111/j.1600-065X.2012.01152.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419491PMC
September 2012

Mammalian target of rapamycin integrates diverse inputs to guide the outcome of antigen recognition in T cells.

J Immunol 2012 May;188(10):4721-9

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.4049/jimmunol.1103143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347776PMC
May 2012

Enhancement of tumor immunotherapy by deletion of the A2A adenosine receptor.

Cancer Immunol Immunother 2012 Jun 25;61(6):917-26. Epub 2011 Nov 25.

Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1007/s00262-011-1155-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589752PMC
June 2012

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.

Nat Immunol 2011 Apr 27;12(4):295-303. Epub 2011 Feb 27.

Sidney-Kimmel Comprehensive Cancer Research Center, Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://www.nature.com/articles/ni.2005
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http://dx.doi.org/10.1038/ni.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077821PMC
April 2011

CD73 is required for efficient entry of lymphocytes into the central nervous system during experimental autoimmune encephalomyelitis.

Proc Natl Acad Sci U S A 2008 Jul 30;105(27):9325-30. Epub 2008 Jun 30.

Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.

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http://dx.doi.org/10.1073/pnas.0711175105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453691PMC
July 2008