Adam Savitz

Adam Savitz

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Adam Savitz

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Pharmacokinetic-Pharmacodynamic Characterization of Relapse Risk for Paliperidone Palmitate 1-Month and 3-Month Formulations.

J Clin Psychopharmacol 2019 Nov/Dec;39(6):567-574

Janssen Research and Development, LLC, Titusville, NJ.

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http://dx.doi.org/10.1097/JCP.0000000000001137DOI Listing
November 2019

Low Incidence of Neuroleptic Malignant Syndrome Associated With Paliperidone Palmitate Long-Acting Injectable: A Database Report and Case Study.

J Clin Psychopharmacol 2019 Mar/Apr;39(2):180-182

The Zucker Hillside Hospital Glen Oaks, NY. and The Donald and Barbara Zucker School of Medicine at Hofstra/Northwell Glen Oaks, NY The Zucker Hillside Hospital Glen Oaks, NY. The Donald and Barbara Zucker School of Medicine at Hofstra/Northwell Glen Oaks, NY and Department of Child and Adolescent Psychiatry Charité Universitätsmedizin Berlin, Germany. Providence Care Hospital Kingston, Ontario, Canada. Janssen Research & Development LLC, Raritan, NJ.

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http://dx.doi.org/10.1097/JCP.0000000000001019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392211PMC
September 2019

Clinical relevance of paliperidone palmitate 3-monthly in treating schizophrenia.

Neuropsychiatr Dis Treat 2019 21;15:1365-1379. Epub 2019 May 21.

The Zucker Hillside Hospital, Psychiatry Research, Glen Oaks, NY, USA.

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http://dx.doi.org/10.2147/NDT.S197225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535080PMC
May 2019

Predictors of achieving remission in schizophrenia patients treated with paliperidone palmitate 3-month formulation.

Neuropsychiatr Dis Treat 2019 22;15:731-737. Epub 2019 Mar 22.

Janssen Scientific Affairs, LLC, Titusville, NJ 08560, USA,

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http://dx.doi.org/10.2147/NDT.S194264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435125PMC
March 2019

Relationship between antipsychotic blood levels and treatment failure during the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) study.

Schizophr Res 2018 11 24;201:324-328. Epub 2018 May 24.

Neurosciences, Janssen Research & Development, 1800 American Boulevard, Pennington, NJ, 08534, United States.

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http://dx.doi.org/10.1016/j.schres.2018.05.028DOI Listing
November 2018

An assessment of injection site reaction and injection site pain of 1-month and 3-month long-acting injectable formulations of paliperidone palmitate.

Perspect Psychiatr Care 2018 Oct 14;54(4):530-538. Epub 2018 Feb 14.

Janssen Scientific Affairs, LLC, Titusville, New Jersey, USA.

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http://dx.doi.org/10.1111/ppc.12267DOI Listing
October 2018

Use of antipsychotic blood levels in clinician decision making: A cross-over study using clinical vignettes of patients with schizophrenia.

Psychiatry Res 2018 09 19;267:25-29. Epub 2018 May 19.

Clinical Research, Neurosciences, Janssen Research & Development, LLC, 1125 Trenton-Harbourton Road, Titusville, NJ 08560, United States.

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http://dx.doi.org/10.1016/j.psychres.2018.05.014DOI Listing
September 2018

The Open Translational Science in Schizophrenia (OPTICS) project: an open-science project bringing together Janssen clinical trial and NIMH data.

NPJ Schizophr 2018 Jun 27;4(1):14. Epub 2018 Jun 27.

Section of General Internal Medicine and the National Clinician Scholars Program, Department of Medicine, Yale University School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1038/s41537-018-0055-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021398PMC
June 2018

Measuring pathology using the PANSS across diagnoses: Inconsistency of the positive symptom domain across schizophrenia, schizoaffective, and bipolar disorder.

Psychiatry Res 2017 12 16;258:207-216. Epub 2017 Aug 16.

University of California, Los Angeles, Department of Psychiatry and Biobehavioral Sciences, Los Angeles, CA, USA; University of California, Los Angeles, Department of Psychology, Los Angeles, CA, USA.

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http://dx.doi.org/10.1016/j.psychres.2017.08.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681392PMC
December 2017

Genome-wide association study of paliperidone efficacy.

Pharmacogenet Genomics 2017 01;27(1):7-18

aNeuroscience, Janssen Research & Development, LLC bJanssen Scientific Affairs, LLC, Titusville cJanssen Research & Development, LLC, Raritan dBlue Note Biosciences, LLC, Princeton, New Jersey eBiostatistics and Bioinformatics, The Scripps Translational Science Institute fDepartment of Molecular and Experimental Medicine, The Scripps Research Institute gScripps Health hHuman Biology, J. Craig Venter Institute, La Jolla iMD Revolution, San Diego, California, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5152628PMC
January 2017

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects.

Authors:
Christian R Marshall Daniel P Howrigan Daniele Merico Bhooma Thiruvahindrapuram Wenting Wu Douglas S Greer Danny Antaki Aniket Shetty Peter A Holmans Dalila Pinto Madhusudan Gujral William M Brandler Dheeraj Malhotra Zhouzhi Wang Karin V Fuentes Fajarado Michelle S Maile Stephan Ripke Ingrid Agartz Margot Albus Madeline Alexander Farooq Amin Joshua Atkins Silviu A Bacanu Richard A Belliveau Sarah E Bergen Marcelo Bertalan Elizabeth Bevilacqua Tim B Bigdeli Donald W Black Richard Bruggeman Nancy G Buccola Randy L Buckner Brendan Bulik-Sullivan William Byerley Wiepke Cahn Guiqing Cai Murray J Cairns Dominique Campion Rita M Cantor Vaughan J Carr Noa Carrera Stanley V Catts Kimberley D Chambert Wei Cheng C Robert Cloninger David Cohen Paul Cormican Nick Craddock Benedicto Crespo-Facorro James J Crowley David Curtis Michael Davidson Kenneth L Davis Franziska Degenhardt Jurgen Del Favero Lynn E DeLisi Dimitris Dikeos Timothy Dinan Srdjan Djurovic Gary Donohoe Elodie Drapeau Jubao Duan Frank Dudbridge Peter Eichhammer Johan Eriksson Valentina Escott-Price Laurent Essioux Ayman H Fanous Kai-How Farh Martilias S Farrell Josef Frank Lude Franke Robert Freedman Nelson B Freimer Joseph I Friedman Andreas J Forstner Menachem Fromer Giulio Genovese Lyudmila Georgieva Elliot S Gershon Ina Giegling Paola Giusti-Rodríguez Stephanie Godard Jacqueline I Goldstein Jacob Gratten Lieuwe de Haan Marian L Hamshere Mark Hansen Thomas Hansen Vahram Haroutunian Annette M Hartmann Frans A Henskens Stefan Herms Joel N Hirschhorn Per Hoffmann Andrea Hofman Hailiang Huang Masashi Ikeda Inge Joa Anna K Kähler René S Kahn Luba Kalaydjieva Juha Karjalainen David Kavanagh Matthew C Keller Brian J Kelly James L Kennedy Yunjung Kim James A Knowles Bettina Konte Claudine Laurent Phil Lee S Hong Lee Sophie E Legge Bernard Lerer Deborah L Levy Kung-Yee Liang Jeffrey Lieberman Jouko Lönnqvist Carmel M Loughland Patrik K E Magnusson Brion S Maher Wolfgang Maier Jacques Mallet Manuel Mattheisen Morten Mattingsdal Robert W McCarley Colm McDonald Andrew M McIntosh Sandra Meier Carin J Meijer Ingrid Melle Raquelle I Mesholam-Gately Andres Metspalu Patricia T Michie Lili Milani Vihra Milanova Younes Mokrab Derek W Morris Bertram Müller-Myhsok Kieran C Murphy Robin M Murray Inez Myin-Germeys Igor Nenadic Deborah A Nertney Gerald Nestadt Kristin K Nicodemus Laura Nisenbaum Annelie Nordin Eadbhard O'Callaghan Colm O'Dushlaine Sang-Yun Oh Ann Olincy Line Olsen F Anthony O'Neill Jim Van Os Christos Pantelis George N Papadimitriou Elena Parkhomenko Michele T Pato Tiina Paunio Diana O Perkins Tune H Pers Olli Pietiläinen Jonathan Pimm Andrew J Pocklington John Powell Alkes Price Ann E Pulver Shaun M Purcell Digby Quested Henrik B Rasmussen Abraham Reichenberg Mark A Reimers Alexander L Richards Joshua L Roffman Panos Roussos Douglas M Ruderfer Veikko Salomaa Alan R Sanders Adam Savitz Ulrich Schall Thomas G Schulze Sibylle G Schwab Edward M Scolnick Rodney J Scott Larry J Seidman Jianxin Shi Jeremy M Silverman Jordan W Smoller Erik Söderman Chris C A Spencer Eli A Stahl Eric Strengman Jana Strohmaier T Scott Stroup Jaana Suvisaari Dragan M Svrakic Jin P Szatkiewicz Srinivas Thirumalai Paul A Tooney Juha Veijola Peter M Visscher John Waddington Dermot Walsh Bradley T Webb Mark Weiser Dieter B Wildenauer Nigel M Williams Stephanie Williams Stephanie H Witt Aaron R Wolen Brandon K Wormley Naomi R Wray Jing Qin Wu Clement C Zai Rolf Adolfsson Ole A Andreassen Douglas H R Blackwood Elvira Bramon Joseph D Buxbaum Sven Cichon David A Collier Aiden Corvin Mark J Daly Ariel Darvasi Enrico Domenici Tõnu Esko Pablo V Gejman Michael Gill Hugh Gurling Christina M Hultman Nakao Iwata Assen V Jablensky Erik G Jönsson Kenneth S Kendler George Kirov Jo Knight Douglas F Levinson Qingqin S Li Steven A McCarroll Andrew McQuillin Jennifer L Moran Bryan J Mowry Markus M Nöthen Roel A Ophoff Michael J Owen Aarno Palotie Carlos N Pato Tracey L Petryshen Danielle Posthuma Marcella Rietschel Brien P Riley Dan Rujescu Pamela Sklar David St Clair James T R Walters Thomas Werge Patrick F Sullivan Michael C O'Donovan Stephen W Scherer Benjamin M Neale Jonathan Sebat

Nat Genet 2017 01 21;49(1):27-35. Epub 2016 Nov 21.

Beyster Center for Psychiatric Genomics, University of California, San Diego, La Jolla, California, USA.

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http://dx.doi.org/10.1038/ng.3725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737772PMC
January 2017

Efficacy and Safety of Paliperidone Palmitate 3-Month Formulation for Patients with Schizophrenia: A Randomized, Multicenter, Double-Blind, Noninferiority Study.

Int J Neuropsychopharmacol 2016 07 5;19(7). Epub 2016 Jul 5.

Janssen Research & Development, LLC, Raritan, New Jersey (Drs Savitz, Xu, Gopal, Nuamah, Ravenstijn, Janik, Schotte, and Hough); Medical University, Innsbruck, Austria (Dr Fleischhacker).

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http://dx.doi.org/10.1093/ijnp/pyw018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966278PMC
July 2016

An examination of neurocognition and symptoms as predictors of post-hospital community tenure in treatment resistant schizophrenia.

Psychiatry Res 2016 Feb 5;236:47-52. Epub 2016 Jan 5.

Department of Psychiatry, Weill Cornell Medical College, 21 Bloomingdale Road, White Plains, NY 10605, USA.

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http://dx.doi.org/10.1016/j.psychres.2016.01.001DOI Listing
February 2016

Altered threat and safety neural processing linked to persecutory delusions in schizophrenia: a two-task fMRI study.

Psychiatry Res 2015 Sep 23;233(3):352-66. Epub 2015 Jun 23.

Functional Neuroimaging Laboratory, Brigham and Women's Hospital, Harvard Medical School, Department of Psychiatry, 824 Boylston Street, Chestnut Hill, MA 02467, USA; Brigham and Women's Hospital, Department of Radiology, Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.pscychresns.2015.06.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003172PMC
September 2015

Long-Term Safety of Paliperidone Extended Release in Adolescents with Schizophrenia: An Open-Label, Flexible Dose Study.

J Child Adolesc Psychopharmacol 2015 Sep 28;25(7):548-57. Epub 2015 Jul 28.

Janssen Research & Development, LLC , Titusville, New Jersey.

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http://dx.doi.org/10.1089/cap.2014.0130DOI Listing
September 2015

SULT4A1 haplotype: conflicting results on its role as a biomarker of antipsychotic response.

Pharmacogenomics 2014 ;15(12):1557-64

Neuroscience Therapeutic Area, Janssen Research & Development, LLC, 1125 Trenton Harbourton Rd, Titusville, NJ, USA.

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http://dx.doi.org/10.2217/pgs.14.105DOI Listing
June 2015

Large-scale candidate gene study to identify genetic risk factors predictive of paliperidone treatment response in patients with schizophrenia.

Pharmacogenet Genomics 2015 Apr;25(4):173-85

aJanssen Research & Development, LLC, Raritan bJanssen Scientific Affairs, LLC, Titusville, New Jersey cJanssen Research & Development, LLC, Titusville, New Jersey, USA.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/FPC.0000000000000122DOI Listing
April 2015

Sparse factors for the positive and negative syndrome scale: which symptoms and stage of illness?

Psychiatry Res 2015 Feb 6;225(3):283-90. Epub 2015 Jan 6.

Department of Psychiatry and Biobehavioral Sciences, University of California, 760 Westwood Plaza, C8-739 Semel Institute, Los Angeles, CA, USA.

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http://dx.doi.org/10.1016/j.psychres.2014.12.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346367PMC
February 2015

Efficacy and safety of paliperidone extended release in adolescents with schizophrenia: a randomized, double-blind study.

J Am Acad Child Adolesc Psychiatry 2015 Feb 25;54(2):126-137.e1. Epub 2014 Nov 25.

Janssen Research and Development, LLC, Titusville, NJ.

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http://dx.doi.org/10.1016/j.jaac.2014.11.009DOI Listing
February 2015

Effect of parental age on treatment response in adolescents with schizophrenia.

Schizophr Res 2013 Dec 18;151(1-3):185-90. Epub 2013 Oct 18.

NYU School of Medicine, Dept. of Psychiatry, InSPIRES, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2013.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208878PMC
December 2013

A novel use of dignity therapy.

Am J Psychiatry 2011 Dec;168(12):1340

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http://dx.doi.org/10.1176/appi.ajp.2011.11030444DOI Listing
December 2011

Carbon dioxide induction of panic anxiety in schizophrenia with auditory hallucinations.

Psychiatry Res 2011 Aug 29;189(1):38-42. Epub 2011 Jun 29.

Department of Psychiarty, Weill Cornell Medical College, White Plains, NY 10605, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S01651781110045
Publisher Site
http://dx.doi.org/10.1016/j.psychres.2011.06.008DOI Listing
August 2011

A comparative study of the MATRICS and IntegNeuro cognitive assessment batteries.

J Clin Exp Neuropsychol 2010 Nov 7;32(9):937-52. Epub 2010 May 7.

University of Medicine and Dentistry of New Jersey-University Behavioral HealthCare, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1080/13803391003596496DOI Listing
November 2010