Adam Eyre-Walker

Adam Eyre-Walker

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Adam Eyre-Walker

Adam Eyre-Walker

Publications by authors named "Adam Eyre-Walker"

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Impact of mutation rate and selection at linked sites on DNA variation across the genomes of humans and other homininae.

Genome Biol Evol 2019 Oct 9. Epub 2019 Oct 9.

Bioinformatics Research Centre Aarhus University, C.F. Møllers Allé 8 DK-8000 Aarhus C, Denmark.

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http://dx.doi.org/10.1093/gbe/evz215DOI Listing
October 2019

Investigating Evolutionary Rate Variation in Bacteria.

J Mol Evol 2019 Sep 30. Epub 2019 Sep 30.

School of Life Sciences, University of Sussex, Brighton, BN1 9QG, UK.

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http://dx.doi.org/10.1007/s00239-019-09912-5DOI Listing
September 2019

Editorial.

Genome Biol Evol 2019 07;11(7):1959

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http://dx.doi.org/10.1093/gbe/evz152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640294PMC
July 2019

The comparative population genetics of and .

PeerJ 2019 27;7:e7216. Epub 2019 Jun 27.

School of Life Sciences, University of Sussex, Brighton, UK.

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http://dx.doi.org/10.7717/peerj.7216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599670PMC
June 2019

Mitochondrial replacement and its effects on human health.

Authors:
Adam Eyre-Walker

Hum Reprod Update 2019 May;25(3):392-394

School of Life Sciences, University of Sussex, Brighton, UK.

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http://dx.doi.org/10.1093/humupd/dmz009DOI Listing
May 2019

Does Adaptive Protein Evolution Proceed by Large or Small Steps at the Amino Acid Level?

Mol Biol Evol 2019 05;36(5):990-998

School of Life Sciences, University of Sussex, Brighton, United Kingdom.

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http://dx.doi.org/10.1093/molbev/msz033DOI Listing
May 2019

Nearly Neutral Evolution across the Drosophila melanogaster Genome.

Mol Biol Evol 2018 11;35(11):2685-2694

School of Life Sciences, University of Sussex, Brighton, United Kingdom.

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http://dx.doi.org/10.1093/molbev/msy164DOI Listing
November 2018

The distribution of bacterial doubling times in the wild.

Proc Biol Sci 2018 06;285(1880)

School of Life Sciences, University of Sussex, Brighton BN1 9QG, UK

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http://dx.doi.org/10.1098/rspb.2018.0789DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015860PMC
June 2018

Large scale variation in the rate of germ-line de novo mutation, base composition, divergence and diversity in humans.

PLoS Genet 2018 03 28;14(3):e1007254. Epub 2018 Mar 28.

School of Life Sciences, University of Sussex, Brighton, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1007254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891062PMC
March 2018

Are pangenomes adaptive or not?

Nat Microbiol 2017 12;2(12):1576

School of Life Sciences, University of Sussex, Falmer, UK.

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http://dx.doi.org/10.1038/s41564-017-0067-5DOI Listing
December 2017

Spontaneous Mutation Rate in the Smallest Photosynthetic Eukaryotes.

Mol Biol Evol 2017 07;34(7):1770-1779

Sorbonne Universités, UPMC Univ Paris 06, CNRS, Biologie Intégrative des Organismes Marins (BIOM), Observatoire Océanologique, Banyuls/Mer, France.

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http://dx.doi.org/10.1093/molbev/msx119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455958PMC
July 2017

Mitochondrial Replacement Therapy: Are Mito-nuclear Interactions Likely To Be a Problem?

Authors:
Adam Eyre-Walker

Genetics 2017 04;205(4):1365-1372

School of Life Sciences, University of Sussex, Brighton BN1 9QG, United Kingdom

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http://dx.doi.org/10.1534/genetics.116.196436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378100PMC
April 2017

Are sites with multiple single nucleotide variants in cancer genomes a consequence of drivers, hypermutable sites or sequencing errors?

PeerJ 2016 20;4:e2391. Epub 2016 Sep 20.

School of Life Sciences, University of Sussex , Brighton , East Sussex , United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036107PMC
http://dx.doi.org/10.7717/peerj.2391DOI Listing
October 2016

Fitness Effects of Spontaneous Mutations in Picoeukaryotic Marine Green Algae.

G3 (Bethesda) 2016 07 7;6(7):2063-71. Epub 2016 Jul 7.

Sorbonne Universités, UPMC Univ Paris 06, CNRS, Biologie Intégrative des Organismes Marins (BIOM), Observatoire Océanologique, F-66650 Banyuls/Mer, France.

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http://dx.doi.org/10.1534/g3.116.029769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938659PMC
July 2016

Molecular Evolutionary Consequences of Island Colonization.

Genome Biol Evol 2016 07 2;8(6):1876-88. Epub 2016 Jul 2.

School of Life Sciences, University of Sussex, Brighton, United Kingdom

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http://sro.sussex.ac.uk/62013/1/JamesGBE16.pdf
Web Search
http://gbe.oxfordjournals.org/lookup/doi/10.1093/gbe/evw120
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http://dx.doi.org/10.1093/gbe/evw120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943191PMC
July 2016

Adaptive Evolution Is Substantially Impeded by Hill-Robertson Interference in Drosophila.

Mol Biol Evol 2016 Feb 22;33(2):442-55. Epub 2015 Oct 22.

Centre for the Study of Evolution, School of Life Sciences, University of Sussex, Brighton, United Kingdom

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http://dx.doi.org/10.1093/molbev/msv236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794616PMC
February 2016

The rate of adaptive evolution in animal mitochondria.

Mol Ecol 2016 Jan 17;25(1):67-78. Epub 2015 Dec 17.

School of Life Sciences, University of Sussex, Brighton, BN1 9QG, UK.

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http://dx.doi.org/10.1111/mec.13475DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737298PMC
January 2016

Rates of Lateral Gene Transfer in Prokaryotes: High but Why?

Trends Microbiol 2015 Oct;23(10):598-605

School of Life Sciences, University of Sussex, Brighton, UK.

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http://dx.doi.org/10.1016/j.tim.2015.07.006DOI Listing
October 2015

Research groups: How big should they be?

PeerJ 2015 9;3:e989. Epub 2015 Jun 9.

School of Life Sciences, University of Sussex , Brighton , United Kingdom.

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http://dx.doi.org/10.7717/peerj.989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465944PMC
June 2015

The role of mutation rate variation and genetic diversity in the architecture of human disease.

PLoS One 2014 27;9(2):e90166. Epub 2014 Feb 27.

School of Life Sciences, University of Sussex, Brighton, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0090166PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937440PMC
October 2014

Fluctuating selection models and McDonald-Kreitman type analyses.

PLoS One 2014 7;9(1):e84540. Epub 2014 Jan 7.

School of Life Sciences, University of Sussex, Brighton, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0084540PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883665PMC
September 2014

How much of the variation in the mutation rate along the human genome can be explained?

G3 (Bethesda) 2014 Jul 3;4(9):1667-70. Epub 2014 Jul 3.

School of Life Sciences, University of Sussex, Brighton, BN1 9QG, United Kingdom.

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http://dx.doi.org/10.1534/g3.114.012849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169158PMC
July 2014

Population size and the rate of evolution.

Trends Ecol Evol 2014 Jan 20;29(1):33-41. Epub 2013 Oct 20.

School of Life Sciences, University of Sussex, Brighton, UK.

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http://dx.doi.org/10.1016/j.tree.2013.09.009DOI Listing
January 2014

ODoSE: a webserver for genome-wide calculation of adaptive divergence in prokaryotes.

PLoS One 2013 6;8(5):e62447. Epub 2013 May 6.

European Centre for Environment and Human Health, The University of Exeter Medical School, University of Exeter, Truro, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0062447PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646019PMC
December 2013

Organellar inheritance in the green lineage: insights from Ostreococcus tauri.

Genome Biol Evol 2013 ;5(8):1503-11

UPMC Univ Paris 06, UMR7232, Observatoire Océanologique, Banyuls-sur-Mer, France.

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http://dx.doi.org/10.1093/gbe/evt106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762196PMC
December 2013

The assessment of science: the relative merits of post-publication review, the impact factor, and the number of citations.

PLoS Biol 2013 Oct 8;11(10):e1001675. Epub 2013 Oct 8.

School of Life Sciences, University of Sussex, Brighton, United Kingdom.

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http://dx.doi.org/10.1371/journal.pbio.1001675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792863PMC
October 2013

A resolution of the mutation load paradox in humans.

Genetics 2012 Aug 1;191(4):1321-30. Epub 2012 Jun 1.

School of Life Sciences, University of Sussex, Brighton BN1 9QG, United Kingdom.

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http://dx.doi.org/10.1534/genetics.112.140343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416010PMC
August 2012

Estimating the rate of adaptive molecular evolution when the evolutionary divergence between species is small.

J Mol Evol 2012 Feb 12;74(1-2):61-8. Epub 2012 Feb 12.

Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, West Mains Road, Edinburgh, EH9 3JT, UK.

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http://dx.doi.org/10.1007/s00239-012-9488-1DOI Listing
February 2012

The large-scale distribution of somatic mutations in cancer genomes.

Hum Mutat 2012 Jan 20;33(1):136-43. Epub 2011 Oct 20.

School of Life Sciences, University of Sussex, Brighton, United Kingdom.

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http://dx.doi.org/10.1002/humu.21616DOI Listing
January 2012

The accumulation of gene regulation through time.

Genome Biol Evol 2011 11;3:667-73. Epub 2011 Mar 11.

School of Life Sciences, University of Sussex, Brighton, United Kingdom.

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http://dx.doi.org/10.1093/gbe/evr019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157833PMC
December 2011

A method for inferring the rate of occurrence and fitness effects of advantageous mutations.

Genetics 2011 Dec 27;189(4):1427-37. Epub 2011 Sep 27.

Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JT, UK.

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http://dx.doi.org/10.1534/genetics.111.131730DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241409PMC
December 2011

Quantifying the variation in the effective population size within a genome.

Genetics 2011 Dec 27;189(4):1389-402. Epub 2011 Sep 27.

School of Life Sciences, University of Sussex, Brighton, BN1 9QG, UK.

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http://dx.doi.org/10.1534/genetics.111.132654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241429PMC
December 2011

Hundreds of putatively functional small open reading frames in Drosophila.

Genome Biol 2011 Nov 25;12(11):R118. Epub 2011 Nov 25.

School of Life Sciences, University of Sussex, Falmer, Brighton, UK.

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http://dx.doi.org/10.1186/gb-2011-12-11-r118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334604PMC
November 2011

Variation in the mutation rate across mammalian genomes.

Nat Rev Genet 2011 Oct 4;12(11):756-66. Epub 2011 Oct 4.

School of Life Sciences, University of Sussex, Brighton BN1 9QG, UK. com

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http://dx.doi.org/10.1038/nrg3098DOI Listing
October 2011

The positive correlation between dN/dS and dS in mammals is due to runs of adjacent substitutions.

Mol Biol Evol 2011 Apr 29;28(4):1371-80. Epub 2010 Nov 29.

Centre for Study of Evolution, School of Life Sciences, University of Sussex, Brighton, United Kingdom.

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http://dx.doi.org/10.1093/molbev/msq320DOI Listing
April 2011

How and why DNA barcodes underestimate the diversity of microbial eukaryotes.

PLoS One 2011 Feb 10;6(2):e16342. Epub 2011 Feb 10.

UPMC Univ Paris 06, UMR 7232, Observatoire Océanologique, Banyuls-sur-Mer, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0016342PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037371PMC
February 2011

Estimation of the neutrality index.

Mol Biol Evol 2011 Jan 13;28(1):63-70. Epub 2010 Sep 13.

Centre for the Study of Evolution, School of Life Sciences, University of Sussex, Brighton, United Kingdom.

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http://dx.doi.org/10.1093/molbev/msq249DOI Listing
January 2011

The genomic distribution and local context of coincident SNPs in human and chimpanzee.

Genome Biol Evol 2010 8;2:547-57. Epub 2010 Jul 8.

Centre for the Study of Evolution, School of Life Sciences, University of Sussex, Brighton, United Kingdom.

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http://dx.doi.org/10.1093/gbe/evq039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997558PMC
December 2010

Evidence of selection upon genomic GC-content in bacteria.

PLoS Genet 2010 Sep 9;6(9):e1001107. Epub 2010 Sep 9.

Centre for the Study of Evolution and School of Life Sciences, University of Sussex, Brighton, United Kingdom.

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https://dx.plos.org/10.1371/journal.pgen.1001107
Publisher Site
http://dx.doi.org/10.1371/journal.pgen.1001107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936529PMC
September 2010

Genome wide analyses reveal little evidence for adaptive evolution in many plant species.

Mol Biol Evol 2010 Aug 18;27(8):1822-32. Epub 2010 Mar 18.

Centre for the Study of Evolution, School of Life Sciences, University of Sussex, Brighton, United Kingdom.

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http://dx.doi.org/10.1093/molbev/msq079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915642PMC
August 2010

Transposable elements: insertion pattern and impact on gene expression evolution in hominids.

Mol Biol Evol 2010 Aug 23;27(8):1955-62. Epub 2010 Mar 23.

Centre for the Study of Evolution, School of Life Sciences, University of Sussex, Brighton, United Kingdom.

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https://academic.oup.com/mbe/article-lookup/doi/10.1093/molb
Publisher Site
http://dx.doi.org/10.1093/molbev/msq084DOI Listing
August 2010

What can we learn about the distribution of fitness effects of new mutations from DNA sequence data?

Philos Trans R Soc Lond B Biol Sci 2010 Apr;365(1544):1187-93

Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, , West Mains Road, Edinburgh EH9 3JT, UK.

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http://dx.doi.org/10.1098/rstb.2009.0266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871813PMC
April 2010

Human triallelic sites: evidence for a new mutational mechanism?

Genetics 2010 Jan 2;184(1):233-41. Epub 2009 Nov 2.

Centre for the Study of Evolution, School of Life Sciences, University of Sussex, Brighton, BN1 9QG, United Kingdom.

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http://dx.doi.org/10.1534/genetics.109.110510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815919PMC
January 2010

Evidence for pervasive adaptive protein evolution in wild mice.

PLoS Genet 2010 Jan 22;6(1):e1000825. Epub 2010 Jan 22.

Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1000825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809770PMC
January 2010

Evolution in health and medicine Sackler colloquium: Genetic architecture of a complex trait and its implications for fitness and genome-wide association studies.

Authors:
Adam Eyre-Walker

Proc Natl Acad Sci U S A 2010 Jan 19;107 Suppl 1:1752-6. Epub 2010 Jan 19.

School of Life Sciences, University of Sussex, Brighton BN1 7FR, United Kingdom.

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http://dx.doi.org/10.1073/pnas.0906182107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868283PMC
January 2010

A problem with the correlation coefficient as a measure of gene expression divergence.

Genetics 2009 Dec 12;183(4):1597-600. Epub 2009 Oct 12.

Centre for the Study of Evolution, School of Life Sciences, University of Sussex, Brighton BN1 9QG, UK.

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http://dx.doi.org/10.1534/genetics.109.110247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787443PMC
December 2009

Estimating the rate of adaptive molecular evolution in the presence of slightly deleterious mutations and population size change.

Mol Biol Evol 2009 Sep 17;26(9):2097-108. Epub 2009 Jun 17.

Centre for the Study of Evolution and School of Life Sciences, University of Sussex, Brighton, United Kingdom.

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http://dx.doi.org/10.1093/molbev/msp119DOI Listing
September 2009

The effect of transposable element insertions on gene expression evolution in rodents.

PLoS One 2009 2;4(2):e4321. Epub 2009 Feb 2.

Centre for the Study of Evolution, School of Life Sciences, University of Sussex, Brighton, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0004321PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2629548PMC
April 2009

Evidence for variation in the effective population size of animal mitochondrial DNA.

PLoS One 2009 9;4(2):e4396. Epub 2009 Feb 9.

UPMC Univ Paris 06, UMR 7628, MBCE, Observatoire Océanologique, Banyuls/mer, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0004396PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635931PMC
April 2009

Cryptic variation in the human mutation rate.

PLoS Biol 2009 Feb;7(2):e1000027

Centre for the Study of Evolution, School of Life Sciences, University of Sussex, Brighton, United Kingdom.

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http://dx.doi.org/10.1371/journal.pbio.1000027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634788PMC
February 2009

Divergence and polymorphism under the nearly neutral theory of molecular evolution.

J Mol Evol 2008 Oct 26;67(4):418-26. Epub 2008 Sep 26.

Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, West Mains Road, Edinburgh, EH9 3JT, UK.

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http://dx.doi.org/10.1007/s00239-008-9146-9DOI Listing
October 2008

The excess of small inverted repeats in prokaryotes.

J Mol Evol 2008 Sep 12;67(3):291-300. Epub 2008 Aug 12.

Centre for the Study of Evolution and School of Life Sciences, University of Sussex, Brighton, UK.

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http://dx.doi.org/10.1007/s00239-008-9151-zDOI Listing
September 2008

The McDonald-Kreitman test and slightly deleterious mutations.

Mol Biol Evol 2008 Jun 14;25(6):1007-15. Epub 2008 Jan 14.

Centre for the Study of Evolution, University of Sussex, Brighton, United Kingdom.

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http://dx.doi.org/10.1093/molbev/msn005DOI Listing
June 2008

The evolution of courtship behaviors through the origination of a new gene in Drosophila.

Proc Natl Acad Sci U S A 2008 May 27;105(21):7478-83. Epub 2008 May 27.

Committee on Genetics, University of Chicago, 920 East 58th Street, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1073/pnas.0800693105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396706PMC
May 2008

The other side of the nearly neutral theory, evidence of slightly advantageous back-mutations.

Proc Natl Acad Sci U S A 2007 Oct 16;104(43):16992-7. Epub 2007 Oct 16.

Centre for the Study of Evolution, School of Life Sciences, University of Sussex, Brighton, United Kingdom.

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http://dx.doi.org/10.1073/pnas.0705456104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2040392PMC
October 2007

The distribution of fitness effects of new mutations.

Nat Rev Genet 2007 Aug;8(8):610-8

Centre for the Study of Evolution, University of Sussex, Brighton, BN1 9QG, UK.

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http://dx.doi.org/10.1038/nrg2146DOI Listing
August 2007

Synonymous codon usage in Escherichia coli: selection for translational accuracy.

Mol Biol Evol 2007 Feb 13;24(2):374-81. Epub 2006 Nov 13.

Ludwig-Maximilan Universität, Biocenter, Planegg-Martinsried, Germany.

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http://dx.doi.org/10.1093/molbev/msl166DOI Listing
February 2007

Searching for sequence directed mutagenesis in eukaryotes.

J Mol Evol 2007 Jan 9;64(1):1-3. Epub 2006 Dec 9.

Centre for Study of Evolution and School of Life Sciences, University of Sussex, Brighton BN1 9QG, UK.

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http://dx.doi.org/10.1007/s00239-005-0120-5DOI Listing
January 2007

A new perspective on isochore evolution.

Gene 2006 Dec 5;385:71-4. Epub 2006 Aug 5.

CNRS UMR 5558, BBE, Université C. Bernard Lyon 1, France.

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http://dx.doi.org/10.1016/j.gene.2006.04.030DOI Listing
December 2006

The genomic rate of adaptive evolution.

Authors:
Adam Eyre-Walker

Trends Ecol Evol 2006 Oct 3;21(10):569-75. Epub 2006 Jul 3.

National Evolutionary Synthesis Center, Durham, NC 27705, USA.

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http://dx.doi.org/10.1016/j.tree.2006.06.015DOI Listing
October 2006

The rate of adaptive evolution in enteric bacteria.

Mol Biol Evol 2006 Jul 18;23(7):1348-56. Epub 2006 Apr 18.

Centre for Study of Evolution, School of Life Sciences, University of Sussex, Brighton, United Kingdom.

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http://dx.doi.org/10.1093/molbev/msk025DOI Listing
July 2006

The distribution of fitness effects of new deleterious amino acid mutations in humans.

Genetics 2006 Jun 17;173(2):891-900. Epub 2006 Mar 17.

School of Life Sciences, University of Sussex, Brighton, UK.

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http://dx.doi.org/10.1534/genetics.106.057570DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1526495PMC
June 2006

Evolution. Size does not matter for mitochondrial DNA.

Authors:
Adam Eyre-Walker

Science 2006 Apr;312(5773):537-8

National Evolutionary Synthesis Center, Durham, NC 27705, USA, and Centre for the Study of Evolution, University of Sussex, Brighton BN1 9QG, UK.

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http://dx.doi.org/10.1126/science.1127182DOI Listing
April 2006

A dissection of volatility in yeast.

Mol Biol Evol 2005 Oct 15;22(10):2022-6. Epub 2005 Jun 15.

Section of Evolutionary Biology, Department Biology II, Ludwig-Maximilians-University Munich, Planegg-Martinsried, Germany.

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http://dx.doi.org/10.1093/molbev/msi192DOI Listing
October 2005

An investigation of the variation in the transition bias among various animal mitochondrial DNA.

Gene 2005 Aug;355:58-66

Centre for the Study of Evolution, School of Biological Sciences, University of Sussex, BN1 9QG Brighton, United Kingdom.

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http://dx.doi.org/10.1016/j.gene.2005.05.019DOI Listing
August 2005

Why are young and old repetitive elements distributed differently in the human genome?

J Mol Evol 2005 Mar;60(3):290-6

Centre for the Study of Evolution, School of Life Sciences, University of Sussex, Brighton, UK.

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http://dx.doi.org/10.1007/s00239-004-0020-0DOI Listing
March 2005

Evidence for widespread degradation of gene control regions in hominid genomes.

PLoS Biol 2005 Feb 25;3(2):e42. Epub 2005 Jan 25.

School of Biological Sciences, University of Edinburgh, United Kingdom.

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http://dx.doi.org/10.1371/journal.pbio.0030042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC544929PMC
February 2005

A broad survey of recombination in animal mitochondria.

Mol Biol Evol 2004 Dec 1;21(12):2319-25. Epub 2004 Sep 1.

Centre for the Study of Evolution, School of Life Sciences, University of Sussex, Brighton, UK.

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http://dx.doi.org/10.1093/molbev/msh244DOI Listing
December 2004

The genomic rate of adaptive amino acid substitution in Drosophila.

Mol Biol Evol 2004 Jul 24;21(7):1350-60. Epub 2004 Mar 24.

Centre for the Study of Evolution and School of Biological Sciences, University of Sussex, Brighton, UK.

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http://dx.doi.org/10.1093/molbev/msh134DOI Listing
July 2004

The decline of isochores in mammals: an assessment of the GC content variation along the mammalian phylogeny.

J Mol Evol 2004 Jun;58(6):653-60

Centre for the Study of Evolution-School of Life Sciences, University of Sussex, Brighton BN1 9QG, UK.

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http://dx.doi.org/10.1007/s00239-004-2587-xDOI Listing
June 2004

Patterns of evolutionary constraints in intronic and intergenic DNA of Drosophila.

Genome Res 2004 Feb;14(2):273-9

University of Edinburgh, School of Biological Sciences, Edinburgh EH9 3JT, UK.

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http://dx.doi.org/10.1101/gr.1329204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC327102PMC
February 2004

The problem of counting sites in the estimation of the synonymous and nonsynonymous substitution rates: implications for the correlation between the synonymous substitution rate and codon usage bias.

Genetics 2003 Nov;165(3):1587-97

Centre for the Study of Evolution and School of Biological Sciences, University of Sussex, Brighton BN1 9QG, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462865PMC
November 2003

Human disease genes: patterns and predictions.

Gene 2003 Oct;318:169-75

Department of Evolutionary Biology, Evolutionary Biology Centre, Uppsala University, Norbyvägen 18D, 752 36 Uppsala, Sweden.

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http://dx.doi.org/10.1016/s0378-1119(03)00772-8DOI Listing
October 2003

Estimating the distribution of fitness effects from DNA sequence data: implications for the molecular clock.

Proc Natl Acad Sci U S A 2003 Sep 18;100(18):10335-40. Epub 2003 Aug 18.

Centre for the Study of Evolution and School of Biological Sciences, University of Sussex, Brighton BN1 9QG, United Kingdom.

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http://dx.doi.org/10.1073/pnas.1833064100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC193562PMC
September 2003

Partitioning the variation in mammalian substitution rates.

Mol Biol Evol 2003 Jan;20(1):10-7

Department of Evolutionary Biology, Evolutionary Biology Centre, Uppsala University, Sweden.

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http://dx.doi.org/10.1093/oxfordjournals.molbev.a004231DOI Listing
January 2003

Quantifying the slightly deleterious mutation model of molecular evolution.

Mol Biol Evol 2002 Dec;19(12):2142-9

Centre for the Study of Evolution & School of Biological Sciences, University of Sussex, Brighton BN1 9QG, UK.

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http://dx.doi.org/10.1093/oxfordjournals.molbev.a004039DOI Listing
December 2002

The evolution of isochores: evidence from SNP frequency distributions.

Genetics 2002 Dec;162(4):1805-10

Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462390PMC
December 2002

Changing effective population size and the McDonald-Kreitman test.

Authors:
Adam Eyre-Walker

Genetics 2002 Dec;162(4):2017-24

Centre for the Study of Evolution, University of Sussex, Brighton BN1 9QG, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462352PMC
December 2002

Analysis of the phylogenetic distribution of isochores in vertebrates and a test of the thermal stability hypothesis.

J Mol Evol 2002 Sep;55(3):356-63

Centre for the Study of Evolution & School of Biological Sciences, University of Sussex, BN1 9QG Brighton, United Kingdom. e.m.s.belle@ sussex.ac.uk

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http://www.lifesci.susx.ac.uk/CSE/members/aeyrewalker/pdfs/B
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http://dx.doi.org/10.1007/s00239-002-2333-1DOI Listing
September 2002

The compositional evolution of the murid genome.

J Mol Evol 2002 Aug;55(2):197-201

Department of Evolutionary Biology, Evolutionary Biology Centre, Uppsala University, Norbyvägen 18D, SE-752 36 Uppsala, Sweden.

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http://dx.doi.org/10.1007/s00239-002-2316-2DOI Listing
August 2002

Adaptive protein evolution in Drosophila.

Nature 2002 Feb;415(6875):1022-4

Centre for the Study of Evolution and School of Biological Sciences, University of Sussex, Brighton BN1 9QG, UK.

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http://www.nature.com/doifinder/10.1038/4151022a
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http://dx.doi.org/10.1038/4151022aDOI Listing
February 2002