Adam Ertel

Adam Ertel

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Adam Ertel

Adam Ertel

Publications by authors named "Adam Ertel"

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69Publications

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Gene expression signatures for HOXA4, HOXA9, and HOXD10 reveal alterations in transcriptional regulatory networks in colon cancer.

J Cell Physiol 2019 Aug 14;234(8):13042-13056. Epub 2018 Dec 14.

Center for Translational Cancer Research, Helen F. Graham Cancer Center and Research Institute, Newark, Delaware.

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http://dx.doi.org/10.1002/jcp.27975DOI Listing
August 2019

Cyclin D1 integrates G9a-mediated histone methylation.

Oncogene 2019 05 4;38(22):4232-4249. Epub 2019 Feb 4.

Pennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, Pennsylvania Biotechnology Center, 3805 Old Easton Rd., Doylestown, PA, 18902, USA.

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http://dx.doi.org/10.1038/s41388-019-0723-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542714PMC
May 2019

Cyclin D1-mediated microRNA expression signature predicts breast cancer outcome.

Theranostics 2018 11;8(8):2251-2263. Epub 2018 Mar 11.

Pennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, Pennsylvania Biotechnology Center and Lankenau Institute for Medical Research, 100 East Lancaster Avenue, Suite, 222, Wynnewood, PA. 19096.

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http://dx.doi.org/10.7150/thno.23877DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928887PMC
April 2019

Exosomal αvβ6 integrin is required for monocyte M2 polarization in prostate cancer.

Matrix Biol 2018 09 9;70:20-35. Epub 2018 Mar 9.

Prostate Cancer Discovery and Development Program, Thomas Jefferson University, Philadelphia, Pennsylvania, USA; Department of Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, USA. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2018.03.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081240PMC
September 2018

Nuclear Pores Promote Lethal Prostate Cancer by Increasing POM121-Driven E2F1, MYC, and AR Nuclear Import.

Cell 2018 08 9;174(5):1200-1215.e20. Epub 2018 Aug 9.

Cancer Biology Department, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA; Medical Oncology Department, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA; Pathology Department, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.07.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150493PMC
August 2018

Recessive mutation in tetraspanin CD151 causes Kindler syndrome-like epidermolysis bullosa with multi-systemic manifestations including nephropathy.

Matrix Biol 2018 03 11;66:22-33. Epub 2017 Nov 11.

Department of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA; Jefferson Institute of Molecular Medicine, Thomas Jefferson University, Philadelphia, PA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0945053X173024
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http://dx.doi.org/10.1016/j.matbio.2017.11.003DOI Listing
March 2018

Blockade of Tumor-Expressed PD-1 promotes lung cancer growth.

Oncoimmunology 2018 29;7(4):e1408747. Epub 2018 Jan 29.

Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, PA, USA.

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http://dx.doi.org/10.1080/2162402X.2017.1408747DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889288PMC
January 2018

Dystrophic Epidermolysis Bullosa: COL7A1 Mutation Landscape in a Multi-Ethnic Cohort of 152 Extended Families with High Degree of Customary Consanguineous Marriages.

J Invest Dermatol 2017 03 27;137(3):660-669. Epub 2016 Oct 27.

Department of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA; Jefferson Institute of Molecular Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.10.023DOI Listing
March 2017

Genome-wide redistribution of MeCP2 in dorsal root ganglia after peripheral nerve injury.

Epigenetics Chromatin 2016 7;9:23. Epub 2016 Jun 7.

Pharmacology and Physiology, Drexel University College of Medicine, 245 North 15th Street, Mail Stop 488, Philadelphia, PA 19102 USA.

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http://dx.doi.org/10.1186/s13072-016-0073-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897807PMC
June 2016

Structure-Based Screen Identifies a Potent Small Molecule Inhibitor of Stat5a/b with Therapeutic Potential for Prostate Cancer and Chronic Myeloid Leukemia.

Mol Cancer Ther 2015 Aug 29;14(8):1777-93. Epub 2015 May 29.

Department of Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania. Department of Urology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania. Department of Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/1535-7163.MCT-14-0883DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547362PMC
August 2015

The endogenous cell-fate factor dachshund restrains prostate epithelial cell migration via repression of cytokine secretion via a cxcl signaling module.

Cancer Res 2015 May 13;75(10):1992-2004. Epub 2015 Mar 13.

Department of Cancer Biology, Thomas Jefferson University, Philadelphia, Pennsylvania. Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania. Kazan Federal University, Kazan, Republic of Tatarstan, Russian Federation.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-0611DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433595PMC
May 2015

Retinoblastoma protein potentiates the innate immune response in hepatocytes: significance for hepatocellular carcinoma.

Hepatology 2014 Oct 28;60(4):1231-40. Epub 2014 Aug 28.

Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX.

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http://dx.doi.org/10.1002/hep.27217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482134PMC
October 2014

Functional significance of macrophage-derived exosomes in inflammation and pain.

Pain 2014 Aug 30;155(8):1527-39. Epub 2014 Apr 30.

Department of Pharmacology & Physiology, Drexel University College of Medicine, Philadelphia, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.pain.2014.04.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106699PMC
August 2014

Cyclin D1 induction of Dicer governs microRNA processing and expression in breast cancer.

Nat Commun 2013 ;4:2812

1] Department of Cancer Biology, Thomas Jefferson University, 233 South 10th Street, Philadelphia, Pennsylvania 19107, USA [2] Kimmel Cancer Center, Thomas Jefferson University, 233 South 10th Street, Philadelphia, Pennsylvania 19107, USA [3] Research Center for Translational Medicine, Key Laboratory for Basic Research in Cardiology, East Hospital, Tongji University School of Medicine, 150 Jimo Road, Shanghai 200120, China.

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http://dx.doi.org/10.1038/ncomms3812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874416PMC
July 2014

Cell fate factor DACH1 represses YB-1-mediated oncogenic transcription and translation.

Cancer Res 2014 Feb 12;74(3):829-39. Epub 2013 Dec 12.

Authors' Affiliations: Department of Cancer Biology; Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania; Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China; and Department of Molecular Oncology, British Columbia Cancer Research Center, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-2466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933065PMC
February 2014

Identification of a cyclin D1 network in prostate cancer that antagonizes epithelial-mesenchymal restraint.

Cancer Res 2014 Jan 26;74(2):508-19. Epub 2013 Nov 26.

Authors' Affiliations: Departments of Cancer Biology, Medical Oncology, and Stem Cell Biology and Regenerative Medicine, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-13-1313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914674PMC
January 2014

EYA1 phosphatase function is essential to drive breast cancer cell proliferation through cyclin D1.

Cancer Res 2013 Jul 1;73(14):4488-99. Epub 2013 May 1.

Department of Cancer Biology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA19107, USA.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-12-4078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755745PMC
July 2013

Dachshund binds p53 to block the growth of lung adenocarcinoma cells.

Cancer Res 2013 Jun 14;73(11):3262-74. Epub 2013 Mar 14.

Departments of Cancer Biology, Stem Cell Biology and Regenerative Medicine, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia,PA 19107, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-3191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674204PMC
June 2013

Aberrant BAF57 signaling facilitates prometastatic phenotypes.

Clin Cancer Res 2013 May 14;19(10):2657-67. Epub 2013 Mar 14.

Department of Cancer Biology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-3049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655134PMC
May 2013

Melanoma adapts to RAF/MEK inhibitors through FOXD3-mediated upregulation of ERBB3.

J Clin Invest 2013 May 1;123(5):2155-68. Epub 2013 Apr 1.

Department of Cancer Biology and Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

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http://dx.doi.org/10.1172/JCI65780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635724PMC
May 2013

Regulation of miR106b cluster through the RB pathway: mechanism and functional targets.

Cell Cycle 2013 Jan 19;12(1):98-111. Epub 2012 Dec 19.

Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.4161/cc.23029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570523PMC
January 2013

The complex transcriptional landscape of the anucleate human platelet.

BMC Genomics 2013 Jan 16;14. Epub 2013 Jan 16.

Cardeza Foundation for Hematologic Research, Division of Hematology, Department of Medicine, Thomas Jefferson University, Philadelphia, PA, USA.

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http://dx.doi.org/10.1186/1471-2164-14-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722126PMC
January 2013

RB-pathway disruption is associated with improved response to neoadjuvant chemotherapy in breast cancer.

Clin Cancer Res 2012 Sep 18;18(18):5110-22. Epub 2012 Jul 18.

Department of Pathology, Thomas Jefferson University, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-0903DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436088PMC
September 2012

CCR5 antagonist blocks metastasis of basal breast cancer cells.

Cancer Res 2012 Aug 25;72(15):3839-50. Epub 2012 May 25.

Kimmel Cancer Center, Department of Cancer Biology and Stem Cell Biology and Regenerative Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-3917DOI Listing
August 2012

Progression of ductal carcinoma in situ to invasive breast cancer is associated with gene expression programs of EMT and myoepithelia.

Breast Cancer Res Treat 2012 Jun 2;133(3):1009-24. Epub 2011 Dec 2.

Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1007/s10549-011-1894-3DOI Listing
June 2012

Mammary gland selective excision of c-jun identifies its role in mRNA splicing.

Cancer Res 2012 Feb 15;72(4):1023-34. Epub 2011 Dec 15.

Department of Cancer Biology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-3647DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288968PMC
February 2012

Variants in genes involved in functional pathways associated with hypertension in African Americans.

Clin Transl Sci 2010 Dec;3(6):279-86

Department of Medicine, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1111/j.1752-8062.2010.00242.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439635PMC
December 2010

Bimodal gene expression and biomarker discovery.

Authors:
Adam Ertel

Cancer Inform 2010 Feb 4;9:11-4. Epub 2010 Feb 4.

Kimmel Cancer Center, Department of Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834379PMC
February 2010

Differential impact of tumor suppressor pathways on DNA damage response and therapy-induced transformation in a mouse primary cell model.

PLoS One 2010 Jan 1;5(1):e8558. Epub 2010 Jan 1.

Kimmel Cancer Center, Department of Cancer Biology, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0008558PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796719PMC
January 2010

Human and mouse switch-like genes share common transcriptional regulatory mechanisms for bimodality.

BMC Genomics 2008 Dec 23;9:628. Epub 2008 Dec 23.

Center for Integrated Bioinformatics, School of Biomedical Engineering, Science and Health Systems, Drexel University, 3141 Chestnut Street, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1186/1471-2164-9-628DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631022PMC
December 2008

Switch-like genes populate cell communication pathways and are enriched for extracellular proteins.

BMC Genomics 2008 Jan 4;9. Epub 2008 Jan 4.

Center for Integrated Bioinformatics, School of Biomedical Engineering, Science and Health Systems, Drexel University, 3141 Chestnut Street, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1186/1471-2164-9-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2257939PMC
January 2008

Prediction potential of candidate biomarker sets identified and validated on gene expression data from multiple datasets.

BMC Bioinformatics 2007 Oct 26;8:415. Epub 2007 Oct 26.

School of Biomedical Engineering, Drexel University, Philadelphia, PA, USA.

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http://dx.doi.org/10.1186/1471-2105-8-415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211325PMC
October 2007

Pathway-specific differences between tumor cell lines and normal and tumor tissue cells.

Mol Cancer 2006 Nov 2;5(1):55. Epub 2006 Nov 2.

Center for Integrated Bioinformatics, School of Biomedical Engineering, Science and Health Systems, Bossone 714, Drexel University, 3143 Chestnut Street, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1186/1476-4598-5-55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635729PMC
November 2006