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Publications Authored by Adam C Resnick | PubFacts
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Immunotherapy for pediatric brain tumors: past and present.

Neuro Oncol 2019 Oct;21(10):1226-1238

Division of Oncology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.

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Source
http://dx.doi.org/10.1093/neuonc/noz077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784275PMC
October 2019

Development and Clinical Validation of a Large Fusion Gene Panel for Pediatric Cancers.

J Mol Diagn 2019 Sep 27;21(5):873-883. Epub 2019 Jun 27.

Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15251578193006
Publisher Site
http://dx.doi.org/10.1016/j.jmoldx.2019.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734859PMC
September 2019

IPMK Mediates Activation of ULK Signaling and Transcriptional Regulation of Autophagy Linked to Liver Inflammation and Regeneration.

Cell Rep 2019 Mar;26(10):2692-2703.e7

The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.02.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494083PMC
March 2019

Novel FGFR2-INA fusion identified in two low-grade mixed neuronal-glial tumors drives oncogenesis via MAPK and PI3K/mTOR pathway activation.

Acta Neuropathol 2018 07 16;136(1):167-169. Epub 2018 May 16.

Center for Data Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, 3501 Civic Center Boulevard, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1007/s00401-018-1864-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015095PMC
July 2018

Author Correction: The landscape of genomic alterations across childhood cancers.

Nature 2018 07;559(7714):E10

Hopp-Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41586-018-0167-2DOI Listing
July 2018

Shared ACVR1 mutations in FOP and DIPG: Opportunities and challenges in extending biological and clinical implications across rare diseases.

Bone 2018 04 2;109:91-100. Epub 2017 Aug 2.

Division of Neurosurgery, The Children's Hospital of Philadelphia, Colket Translational Research Building Room 4052, 3501 Civic Center Blvd, Philadelphia 19104, PA, United States; Department of Biomedical and Health Informatics, The Children's Hospital of Philadelphia, Colket Translational Research Building Room 4052, 3501 Civic Center Blvd, Philadelphia 19104, PA, United States; Center for Data Driven Discovery in Biomedicine, The Children's Hospital of Philadelphia, Colket Translational Research Building Room 4052, 3501 Civic Center Blvd, Philadelphia 19104, PA, United States; Center for Childhood Cancer Research, The Children's Hospital of Philadelphia, Colket Translational Research Building Room 4052, 3501 Civic Center Blvd, Philadelphia 19104, PA, United States; Department of Neurosurgery, Perelman School of Medicine at the University of Pennsylvania, 3501 Civic Center Blvd, Room 4052, Philadelphia 19104, PA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2017.08.001DOI Listing
April 2018

The landscape of genomic alterations across childhood cancers.

Nature 2018 03 28;555(7696):321-327. Epub 2018 Feb 28.

Hopp-Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature25480DOI Listing
March 2018

MYB-QKI drives childhood brain tumors via tripartite mechanism.

Cell Cycle 2017 03 14;16(5):390-391. Epub 2016 Dec 14.

a Center for Data Driven Discovery in Biomedicine (D3b) , The Children's Hospital of Philadelphia , Philadelphia , PA , USA.

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http://dx.doi.org/10.1080/15384101.2016.1260990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351923PMC
March 2017

BRAF Status in Personalizing Treatment Approaches for Pediatric Gliomas.

Clin Cancer Res 2016 Nov 23;22(21):5312-5321. Epub 2016 May 23.

Brain Tumor Research Center, University of California, San Francisco, Helen-Diller Cancer Diller Cancer Research Center, San Francisco, California.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-1101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093033PMC
November 2016

Inositol polyphosphates intersect with signaling and metabolic networks via two distinct mechanisms.

Proc Natl Acad Sci U S A 2016 11 19;113(44):E6757-E6765. Epub 2016 Oct 19.

Department of Chemistry, Princeton University, Princeton, NJ 08544;

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http://dx.doi.org/10.1073/pnas.1606853113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098652PMC
November 2016

The biorepository portal toolkit: an honest brokered, modular service oriented software tool set for biospecimen-driven translational research.

BMC Genomics 2016 08 18;17 Suppl 4:434. Epub 2016 Aug 18.

Department of Biomedical and Health Informatics, The Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA, USA.

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http://bmcgenomics.biomedcentral.com/articles/10.1186/s12864
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http://dx.doi.org/10.1186/s12864-016-2797-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001241PMC
August 2016

Phase II study of sorafenib in children with recurrent or progressive low-grade astrocytomas.

Neuro Oncol 2014 Oct 6;16(10):1408-16. Epub 2014 May 6.

NYU Comprehensive Neurofibromatosis Center, Division of Pediatric Hematology/Oncology, Department of Pediatrics and Laura and Isaac Perlmutter Cancer Center at NYU Langone Medical Center, New York, New York (M.A.K., G.L., A.M., J.C.A.); Division of Oncology, Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania (M.J.F., A.J.S.); Department of Radiology, NYU Langone Medical Center, New York, New York (S.S.M., M.C.B.); The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland (K.J.C.); Division of Pediatric Neurosurgery, Department of Neurosurgery, NYU Langone Medical Center, New York, New York (J.H.W., D.H.H.); Division of Biostatistics, Department of Population Health and The Laura and Isaac Perlmutter Cancer Center at NYU Langone Medical Center, New York, New York (J.D.G., T.H.); Department of Neurosurgery, Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania (A.C.R); Division of Hematology/Oncology, Children's Hospital Los Angeles, Los Angeles, California (G.D.); German Cancer Research Center and University Hospital, Heidelberg, Germany (D.T.W.J., A.K., S.M.P.); Division of Neuropathology, Department of Pathology, Johns Hopkins University, Baltimore, Maryland (C.G.E.); Division of Neuropathology, Department of Pathology, Department of Neurosurgery and Laura and Isaac Perlmutter Cancer Center at NYU Langone Medical Center, New York, New York (D.Z.).

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http://dx.doi.org/10.1093/neuonc/nou059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165419PMC
October 2014

Elucidating diphosphoinositol polyphosphate function with nonhydrolyzable analogues.

Angew Chem Int Ed Engl 2014 Jul 30;53(28):7192-7. Epub 2014 May 30.

Department of Chemistry, Princeton University, Washington Rd, Princeton, NJ 08544 (USA).

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http://dx.doi.org/10.1002/anie.201402905DOI Listing
July 2014

Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas.

Nat Genet 2014 Feb 12;46(2):161-5. Epub 2014 Jan 12.

1] Harvard Medical School, Boston, Massachusetts, USA. [2] Department of Pathology, Boston Children's Hospital, Boston, Massachusetts, USA. [3] Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, USA. [4] Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA. [5].

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http://dx.doi.org/10.1038/ng.2868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982316PMC
February 2014

Paradoxical activation and RAF inhibitor resistance of BRAF protein kinase fusions characterizing pediatric astrocytomas.

Proc Natl Acad Sci U S A 2013 Apr 26;110(15):5957-62. Epub 2013 Mar 26.

Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1073/pnas.1219232110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625308PMC
April 2013

Inositol polyphosphate multikinase is a physiologic PI3-kinase that activates Akt/PKB.

Proc Natl Acad Sci U S A 2011 Jan 10;108(4):1391-6. Epub 2011 Jan 10.

The Solomon H. Snyder Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1073/pnas.1017831108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029688PMC
January 2011

Activating mutations in BRAF characterize a spectrum of pediatric low-grade gliomas.

Neuro Oncol 2010 Jul 14;12(7):621-30. Epub 2010 Feb 14.

The Children's Hospital of Philadelphia, Room 1002 Abramson Research Building, 3615 Civic Center Boulevard, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1093/neuonc/noq007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940652PMC
July 2010

Gene deletion of inositol hexakisphosphate kinase 1 reveals inositol pyrophosphate regulation of insulin secretion, growth, and spermiogenesis.

Proc Natl Acad Sci U S A 2008 Feb 11;105(7):2349-53. Epub 2008 Feb 11.

The Solomon H. Snyder Department of Neuroscience and Departments of Pharmacology and Molecular Sciences and Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0712227105
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http://dx.doi.org/10.1073/pnas.0712227105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268139PMC
February 2008

Protein pyrophosphorylation by inositol pyrophosphates is a posttranslational event.

Proc Natl Acad Sci U S A 2007 Sep 14;104(39):15305-10. Epub 2007 Sep 14.

The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1073/pnas.0707338104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2000531PMC
September 2007

Inositol polyphosphate multikinase is a nuclear PI3-kinase with transcriptional regulatory activity.

Proc Natl Acad Sci U S A 2005 Sep 25;102(36):12783-8. Epub 2005 Aug 25.

Department of Neuroscience, Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1073/pnas.0506184102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1200306PMC
September 2005

Inositol pyrophosphates regulate cell death and telomere length through phosphoinositide 3-kinase-related protein kinases.

Proc Natl Acad Sci U S A 2005 Feb 21;102(6):1911-4. Epub 2005 Jan 21.

Department of Neuroscience, Pharmacology and Molecular Sciences, and Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1073/pnas.0409322102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC548528PMC
February 2005

Phosphorylation of proteins by inositol pyrophosphates.

Science 2004 Dec;306(5704):2101-5

Department of Neuroscience, Johns Hopkins University, School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA.

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http://www.sciencemag.org/cgi/doi/10.1126/science.1103344
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December 2004

UDP-glucuronate decarboxylase, a key enzyme in proteoglycan synthesis: cloning, characterization, and localization.

J Biol Chem 2002 May 27;277(19):16968-75. Epub 2002 Feb 27.

Department of Neurological Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1074/jbc.M109316200DOI Listing
May 2002