Adam Brufsky

Adam Brufsky

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Adam Brufsky

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Neratinib: the emergence of a new player in the management of HER2+ breast cancer brain metastasis.

Future Oncol 2020 Mar 14;16(7):247-254. Epub 2020 Feb 14.

UPMC Hillman Cancer Center, Magee Women's Hospital, Suite 4628, 300 Halket Street, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.2217/fon-2019-0719DOI Listing
March 2020

Capivasertib inhibits a key pathway in metastatic breast cancer.

Lancet Oncol 2020 Feb 5. Epub 2020 Feb 5.

Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(19)30857-5DOI Listing
February 2020

Adjuvant bisphosphonate therapy in early-stage breast cancer-Treating the soil to kill the seed.

Breast J 2020 01 26;26(1):65-68. Epub 2019 Dec 26.

Welcare Hospital, KIochi &MOSC Medical College, Kolenchery, Kerala, India.

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http://dx.doi.org/10.1111/tbj.13730DOI Listing
January 2020

The Association of Modifiable Breast Cancer Risk Factors and Somatic Genomic Alterations in Breast Tumors: The Cancer Genome Atlas Network.

Cancer Epidemiol Biomarkers Prev 2020 Jan 13. Epub 2020 Jan 13.

Channing Division of Network Medicine, Department of Medicine, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1158/1055-9965.EPI-19-1087DOI Listing
January 2020

A clinical decision support system learned from data to personalize treatment recommendations towards preventing breast cancer metastasis.

PLoS One 2019 8;14(3):e0213292. Epub 2019 Mar 8.

Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0213292PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407919PMC
December 2019

Bisphosphonate Choice as Adjuvant Therapy for Breast Cancer: Does It Matter?

J Natl Cancer Inst 2019 Nov 6. Epub 2019 Nov 6.

Welcare Hospital, Kochi, & MOSC Medical College, Kolenchery, Kerala, India.

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http://dx.doi.org/10.1093/jnci/djz216DOI Listing
November 2019

Treatment Patterns and Outcomes Associated With Palbociclib Plus Letrozole for Postmenopausal Women With HR/HER2 Advanced Breast Cancer Enrolled in an Expanded Access Program.

Clin Breast Cancer 2019 Oct 18;19(5):317-325.e4. Epub 2019 Apr 18.

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, MD.

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http://dx.doi.org/10.1016/j.clbc.2019.04.005DOI Listing
October 2019

CDK4/6 inhibitors: taking the place of chemotherapy?

Lancet Oncol 2019 Oct 4;20(10):1329-1330. Epub 2019 Sep 4.

University of Pittsburgh, Magee-Women's Hospital, Pittsburgh, PA, 15213, USA. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(19)30507-8DOI Listing
October 2019

A Predictor of Pathological Complete Response to Neoadjuvant Chemotherapy Stratifies Triple Negative Breast Cancer Patients with High Risk of Recurrence.

Sci Rep 2019 Oct 16;9(1):14863. Epub 2019 Oct 16.

Division of Hematology/Oncology, University of Pittsburg School of Medicine, 300 Halket St # 4628, Pittsburgh, PA, 15213, USA.

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http://dx.doi.org/10.1038/s41598-019-51335-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795899PMC
October 2019

Features Associated With Long-Term Survival in Patients With Metastatic Breast Cancer.

Clin Breast Cancer 2019 08 6;19(4):304-310. Epub 2019 Feb 6.

Division of Hematology/Oncology, University of Pittsburgh Medical Center, Pittsburgh, PA; UPMC Hillman Cancer Center, Pittsburgh, PA. Electronic address:

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http://dx.doi.org/10.1016/j.clbc.2019.01.014DOI Listing
August 2019

Artificial intelligence-directed prognostication of breast cancer.

EBioMedicine 2019 Aug 1;46:6-7. Epub 2019 Aug 1.

University of Pittsburgh, 300 Halket Street, Pittsburgh, PA 15213, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.07.073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712046PMC
August 2019

Clinical and Genomic Risk to Guide the Use of Adjuvant Therapy for Breast Cancer.

N Engl J Med 2019 06 3;380(25):2395-2405. Epub 2019 Jun 3.

From Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY (J.A.S., D.F.M.); Dana-Farber Cancer Institute, Boston (R.J.G.); University of Texas, San Antonio (P.M.R.); Sunnybrook Research Institute, Toronto (K.I.P.), and McMaster University, Hamilton, ON (T.J.W.) - both in Canada; Loyola University Medical Center, Maywood (K.S.A.), and Northwestern University, Chicago (L.I.W., V.G.K.) - both in Illinois; University of Michigan, Ann Arbor (D.F.H.); Virginia Commonwealth University School of Medicine and the Massey Cancer Center, Richmond (C.E.G.); University of North Carolina, Chapel Hill (E.C.D.), and Duke University Medical Center, Durham (J.A.O., J.A.) - both in North Carolina; Mayo Clinic, Jacksonville, FL (M.P.G.); National Institutes of Health, National Cancer Institute, Bethesda, MD (T.L.); Indiana University School of Medicine (S.S.B.) and Indiana University Hospital (G.W.S.), Indianapolis; Vince Lombardi Cancer Clinic, Two Rivers (T.J.S.), and Fox Valley Hematology and Oncology, Appleton (T.F.G.) - both in Wisconsin; Washington University, St. Louis (M.J.E.); the National Surgical Adjuvant Breast and Bowel Project Pathology Office (S.P.) and the University of Pittsburgh (A.M.B.), Pittsburgh; Emory University, Atlanta (W.C.W.); Cancer Trials Ireland, Dublin (M.M.K.); Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru (H.L.G.M.); Cancer Center of Kansas, Wichita (P.S.R.); Vanderbilt University, Nashville (I.A.M.); Rutgers Cancer Institute of New Jersey, New Brunswick (D.L.T.); and the University of Hawaii Cancer Center, Honolulu (J.L.B.).

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http://dx.doi.org/10.1056/NEJMoa1904819DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709671PMC
June 2019

Metastatic Breast Cancer Patient With Activating HER2 Exon 20 Insertion Mutation With Response to Poziotinib: Case Report of Compassionate Drug Use.

Clin Breast Cancer 2019 02 4;19(1):e7-e11. Epub 2018 Oct 4.

Division of Hematology/Oncology, Comprehensive Breast Cancer Center, University of Pittsburgh Medical Center, Magee Women's Center, Pittsburgh, PA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15268209183031
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http://dx.doi.org/10.1016/j.clbc.2018.09.010DOI Listing
February 2019

Targeted mutation detection in breast cancer using MammaSeq™.

Breast Cancer Res 2019 02 8;21(1):22. Epub 2019 Feb 8.

Department of Pharmacology and Chemical Biology, and Human Genetics, UPMC Hillman Cancer Center, Magee-Womens Research Institute, University of Pittsburgh, 204 Craft Avenue, Pittsburgh, PA, 15213, USA.

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https://breast-cancer-research.biomedcentral.com/articles/10
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http://dx.doi.org/10.1186/s13058-019-1102-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368740PMC
February 2019

Extended adjuvant therapy for early-stage breast cancer: Are there markers for its use?

Breast J 2019 01;25(1):7-8

Magee-Women's Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1111/tbj.13038DOI Listing
January 2019

Statin drugs to reduce breast cancer recurrence and mortality.

Breast Cancer Res 2018 11 20;20(1):144. Epub 2018 Nov 20.

Department of Pathology, University of Pittsburgh, Pittsburgh, 15231, PA, USA.

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http://dx.doi.org/10.1186/s13058-018-1066-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247616PMC
November 2018

Whole genome amplification of cell-free DNA enables detection of circulating tumor DNA mutations from fingerstick capillary blood.

Sci Rep 2018 11 23;8(1):17313. Epub 2018 Nov 23.

Women's Cancer Research Center, Department of Pharmacology and Chemical Biology, UPMC Hillman Cancer Center, Magee Womens Research Institute, Pittsburgh, PA, 15213, USA.

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http://dx.doi.org/10.1038/s41598-018-35470-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251935PMC
November 2018

Double-Blind Phase III Trial of Adjuvant Chemotherapy With and Without Bevacizumab in Patients With Lymph Node-Positive and High-Risk Lymph Node-Negative Breast Cancer (E5103).

J Clin Oncol 2018 09 24;36(25):2621-2629. Epub 2018 Jul 24.

Kathy D. Miller, Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, IN; Anne O'Neill, Dana-Farber Cancer Institute, Boston, MA; William Gradishar, Northwestern University, Chicago; Nguyet Anh Le-Lindqwister, Heartland Cancer Research National Cancer Institute Community Oncology Research Program, Peoria, IL; Timothy J. Hobday, Mayo Clinic, Rochester; Stuart Bloom, Abbott Northwestern Hospital, Minneapolis, MN; Lori J. Goldstein, Fox Chase Cancer Center, Philadelphia; Adam M. Brufsky, University of Pittsburgh, Pittsburgh, PA; Ingrid A. Mayer, Vanderbilt University, Nashville, TN; Amye J. Tevaarwerk, University of Wisconsin, Madison, WI; Joseph A. Sparano, Montefiore Hospital and Medical Center, Bronx; Chau T. Dang, Memorial Sloan Kettering Cancer Center, New York, NY; Carolyn B. Hendricks, Association Community Clinical Oncology Program, Bethesda, MD; Donald W. Northfelt, Mayo Clinic, Scottsdale, AZ; and George W. Sledge JR, Stanford University, Stanford, CA.

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http://dx.doi.org/10.1200/JCO.2018.79.2028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118403PMC
September 2018

Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer.

N Engl J Med 2018 Jul 3;379(2):111-121. Epub 2018 Jun 3.

From Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY (J.A.S., D.F.M.); Dana-Farber Cancer Institute, Boston (R.J.G.); Sunnybrook Research Institute, Toronto (K.I.P.), and McMaster University, Hamilton, ON (T.J.W.) - both in Canada; Loyola University Chicago Stritch School of Medicine, Maywood (K.S.A.), and Northwestern University, Chicago (L.I.W., V.G.K.) - both in Illinois; University of Michigan, Ann Arbor (D.F.H.); Virginia Commonwealth University School of Medicine and the Massey Cancer Center, Richmond (C.E.G.); University of North Carolina, Chapel Hill (E.C.D.), and Duke University Medical Center, Durham (J.A.O.) - both in North Carolina; Mayo Clinic, Jacksonville, FL (M.P.G.); National Institutes of Health, National Cancer Institute, Bethesda, MD (T.L., J.A.); Indiana University School of Medicine (S.S.B.) and Indiana University Hospital (G.W.S.), Indianapolis; Vince Lombardi Cancer Clinic, Two Rivers (T.J.S.), and Fox Valley Hematology and Oncology, Appleton (T.F.G.) - both in Wisconsin; Washington University, St. Louis (M.J.E.); National Surgical Adjuvant Breast and Bowel Project Pathology Office (S.P.) and University of Pittsburgh (A.M.B.), Pittsburgh; Emory University, Atlanta (W.C.W.); University of Texas, San Antonio (P.M.R.); Cancer Trials Ireland, Dublin (M.M.K.); Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru (H.L.G.M.); Cancer Center of Kansas, Wichita (P.S.R.); Vanderbilt University, Nashville (I.A.M.); Rutgers Cancer Institute of New Jersey, New Brunswick (D.L.T.); and University of Hawaii Cancer Center, Honolulu (J.L.B.).

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http://www.nejm.org/doi/10.1056/NEJMoa1804710
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http://dx.doi.org/10.1056/NEJMoa1804710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172658PMC
July 2018

Randomized Phase II Trial of Fulvestrant Plus Everolimus or Placebo in Postmenopausal Women With Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Metastatic Breast Cancer Resistant to Aromatase Inhibitor Therapy: Results of PrE0102.

J Clin Oncol 2018 06 17;36(16):1556-1563. Epub 2018 Apr 17.

Noah Kornblum, Della F. Makower, and Joseph A. Sparano, Albert Einstein College of Medicine, Bronx; Paula Klein, Mount Sinai Beth Israel Comprehensive Cancer Center, New York, NY; Fengmin Zhao and Judith Manola, Dana-Farber Cancer Institute, Boston, MA; Bhuvaneswari Ramaswamy, The Ohio State University Comprehensive Cancer Center, Columbus, OH; Adam Brufsky, University of Pittsburgh, Pittsburgh; Cristina I. Truica, Penn State Cancer Institute, Hershey; Lori J. Goldstein, Fox Chase Cancer Center, Philadelphia, PA; Phillip J. Stella, Saint Joseph Mercy (Michigan Cancer Consortium), Ann Arbor, MI; Brian Burnette, Saint Vincent Hospital, Green Bay; Timothy R. Wassenaar, Pro Health Care, Waukesha, WI; Melinda Telli, Stanford University School of Medicine, Stanford, CA; Puneet Cheema, Metro-Minnesota Community Oncology Research Consortium, Saint Louis Park, MN; Antonio C. Wolff, Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD; Gamini S. Soori, Missouri Valley Cancer Consortium, Omaha, NE; Barbara Haley, UT Southwestern Medical Center, Dallas, TX; and Kathy D. Miller, Indiana University School of Medicine, Indianapolis, IN.

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http://dx.doi.org/10.1200/JCO.2017.76.9331DOI Listing
June 2018

Estrogen Receptor-Positive Breast Cancer: Exploiting Signaling Pathways Implicated in Endocrine Resistance.

Oncologist 2018 05 19;23(5):528-539. Epub 2018 Jan 19.

Memorial Sloan Kettering Cancer Center, New York City, New York, USA.

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http://dx.doi.org/10.1634/theoncologist.2017-0423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947450PMC
May 2018

Long-term Peripheral Neuropathy in Breast Cancer Patients Treated With Adjuvant Chemotherapy: NRG Oncology/NSABP B-30.

J Natl Cancer Inst 2018 02;110(2)

NRG Oncology and The University of Pittsburgh, Pittsburgh, PA; Center for Healthcare Policy and Research, University of California Davis, Sacramento, CA; Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD; NRG Oncology and The Washington Cancer Institute at Washington Hospital Center, Washington, DC and current: Georgetown University, Washington, DC; NRG Oncology and The Colorado Cancer Research Program, Denver, CO; NRG Oncology and Kaiser Permanente, Northern California, Vallejo, CA; NRG Oncology and The Central Illinois CCOP Heartland NCORP, Decatur, IL; NRG Oncology and The University of Pittsburgh/Magee Womens Hospital, Pittsburgh, PA; NRG Oncology and The Allegheny Health Network, Pittsburgh, PA; NRG Oncology and The Jewish General Hospital, McGill University, Montréal, QC, Canada; NRG Oncology and The MedStar Franklin Square Medical Center/Harry and Jeanette Weinberg Cancer Institute, Baltimore, MD; NRG Oncology and The University of California Los Angeles, Schools of Medicine and Public Health, Los Angeles, CA; Jonsson Comprehensive Cancer Center at UCLA, Los Angeles, CA.

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http://dx.doi.org/10.1093/jnci/djx162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825682PMC
February 2018

Long-Term Follow-Up of Cardiac Function and Quality of Life for Patients in NSABP Protocol B-31/NRG Oncology: A Randomized Trial Comparing the Safety and Efficacy of Doxorubicin and Cyclophosphamide (AC) Followed by Paclitaxel With AC Followed by Paclitaxel and Trastuzumab in Patients With Node-Positive Breast Cancer With Tumors Overexpressing Human Epidermal Growth Factor Receptor 2.

J Clin Oncol 2017 Dec 26;35(35):3942-3948. Epub 2017 Oct 26.

All authors: National Surgical Adjuvant Breast and Bowel Project/NRG Oncology; Reena S. Cecchini, Priya Rastogi, Jong-Hyeon Jeong, and Adam M. Brufsky, University of Pittsburgh; Priya Rastogi and Adam M. Brufsky, Magee-Womens Hospital; Norman Wolmark, Allegheny Health Network Cancer Institute, Pittsburgh, PA; Patricia A. Ganz, University of California at Los Angeles, Los Angeles; Louis Fehrenbacher, Kaiser Permanente, Vallejo; Jonathan Polikoff, Kaiser Permanente, San Marco, CA; Edward H. Romond, University of Kentucky, Lexington, KY; Charles E. Geyer Jr, Virginia Commonwealth University, Richmond, VA; Sandra M. Swain and John L. Zapas, MedStar Washington Hospital Center, Washington, DC; Howard M. Gross, Dayton National Cancer Institute Community Oncology Research Program (NCORP), Dayton, OH; Patrick J. Flynn, Metro-Minnesota Community Clinical Oncology Program (CCOP), Woodbury, MN; Tanya A. Wahl, Fred Hutchinson Cancer Research Center, Seattle, WA; Thomas E. Seay, Atlanta Regional CCOP, Atlanta, GA; James L. Wade III, Heartland NCORP, Decatur, IL; David D. Biggs, Christiana Care Health System, Newark, DE; James N. Atkins, Southeast Clinical Oncology Research Consortium NCORP, Goldsboro, NC; and Eleftherios P. Mamounas, Orlando Health, Orlando, FL.

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http://dx.doi.org/10.1200/JCO.2017.74.1165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721228PMC
December 2017

Long-term management of patients with hormone receptor-positive metastatic breast cancer: Concepts for sequential and combination endocrine-based therapies.

Authors:
Adam M Brufsky

Cancer Treat Rev 2017 Sep 6;59:22-32. Epub 2017 Jul 6.

University of Pittsburgh, School of Medicine, 300 Halket Street, Suite 4628, Pittsburgh, PA 15213, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ctrv.2017.06.004DOI Listing
September 2017

Alcohol consumption and breast tumor gene expression.

Breast Cancer Res 2017 Sep 12;19(1):108. Epub 2017 Sep 12.

Department of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts Amherst, 715 N Pleasant Street, Amherst, MA, 01003, USA.

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http://dx.doi.org/10.1186/s13058-017-0901-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596493PMC
September 2017

Anthracyclines in Early Breast Cancer: The ABC Trials-USOR 06-090, NSABP B-46-I/USOR 07132, and NSABP B-49 (NRG Oncology).

J Clin Oncol 2017 Aug 11;35(23):2647-2655. Epub 2017 Apr 11.

Joanne L. Blum, Lina Asmar, Nicholas J. Robert, Joyce A. O'Shaughnessy, Svetislava J. Vukelja, Devchand Paul, and Stephen E. Jones, US Oncology Research; Lina Asmar, McKesson Specialty Health, The Woodlands; Joanne L. Blum and Joyce A. O'Shaughnessy, Texas Oncology-Baylor Charles A. Sammons Cancer Center, Baylor University Medical Center, Dallas; Svetislava J. Vukelja, Texas Oncology-Tyler, Tyler, TX; Patrick J. Flynn, Charles E. Geyer Jr, Samuel A. Jacobs, Judith O. Hopkins, Louis Fehrenbacher, Alan P. Lyss, Adam M. Brufsky, Sandra M. Swain, Eleftherios P. Mamounas, and Norman Wolmark, National Surgical Adjuvant Breast and Bowel Project/NRG Oncology; Greg Yothers, Jong-Hyeon Jeong, and Linda H. Colangelo, NRG Oncology; Greg Yothers, John-Hyeon Jeong, and Linda H. Colangelo, The University of Pittsburgh; Samuel A. Jacobs, University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine; Adam M. Brufsky, Magee-Womens Hospital at University of Pittsburgh Medical Center; Norman Wolmark, Allegheny Cancer Center at Allegheny General Hospital, Pittsburgh; Henry Leonidas Gómez, Eastern Cooperative Oncology Group-American College of Radiology Imaging Network, Philadelphia, PA; Patrick J. Flynn, Metro-Minnesota Community Oncology Research Consortium, Minneapolis, MN; Charles E. Geyer Jr, Massey Cancer Center, Virginia Commonwealth University, Richmond; Nicholas J. Robert, Virginia Cancer Specialists, Fairfax, VA; Judith O. Hopkins, The Southeastern Medical Oncology Center, Goldsboro, NC; Chau T. Dang, The Alliance, Boston, MA; Chau T. Dang, Memorial Sloan Kettering Cancer Center, New York, NY; Henry Leonidas Gómez, Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru; Louis Fehrenbacher, Kaiser Permanente Oncology Clinical Trials Northern California, Vallejo, CA; Alan P. Liss, Heartland Cancer Research National Cancer Institute Community Oncology Research Program at Missouri Baptist Cancer Center, St Louis, MO; Devchand Paul, Rocky Mountain Cancer Centers, Denver, CO; Sandra M. Swain, MedStar Washington Hospital Center Washington Cancer Institute, and Georgetown University Medical Center, Washington, DC; and Eleftherios P. Mamounas, UF Cancer Center at Orlando Health, Orlando, FL.

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http://ascopubs.org/doi/10.1200/JCO.2016.71.4147
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http://dx.doi.org/10.1200/JCO.2016.71.4147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549453PMC
August 2017

Characterizing Molecular Variants and Clinical Utilization of Next-generation Sequencing in Advanced Breast Cancer.

Appl Immunohistochem Mol Morphol 2017 07;25(6):392-398

Departments of *Pathology, Division of Breast & Gynecologic Pathology ‡Oncology, Magee-Womens Hospital †Pathology, Division of Molecular & Genomic Pathology §Magee-Womens Research Institute & Foundation, The University of Pittsburgh Medical Center, Pittsburgh, PA.

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http://dx.doi.org/10.1097/PAI.0000000000000322DOI Listing
July 2017

TACT2: improving treatment tolerability in early breast cancer.

Lancet Oncol 2017 07;18(7):843-845

University of Pittsburgh, Pittsburgh, PA 15213, USA. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(17)30437-0DOI Listing
July 2017

Estradiol as a Targeted, Late-Line Therapy in Metastatic Breast Cancer with Estrogen Receptor Amplification.

Cureus 2017 Jul 6;9(7):e1434. Epub 2017 Jul 6.

Pharmacology and Chemical Biology, University Of Pittsburgh.

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http://dx.doi.org/10.7759/cureus.1434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587405PMC
July 2017

Symptom incidence, distress, cancer-related distress, and adherence to chemotherapy among African American women with breast cancer.

Cancer 2017 06 15;123(11):2061-2069. Epub 2017 Feb 15.

Acute and Tertiary Care Department, University of Pittsburgh School of Nursing, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1002/cncr.30575DOI Listing
June 2017

Intrinsic Subtype Switching and Acquired ERBB2/HER2 Amplifications and Mutations in Breast Cancer Brain Metastases.

JAMA Oncol 2017 May;3(5):666-671

Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania2Women's Cancer Research Center, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania3Magee-Women's Research Institute, Magee-Women's Research Hospital of University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania7Department of Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1001/jamaoncol.2016.5630DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508875PMC
May 2017

Less is more? De-intensification of therapy for early-stage HER2-positive breast cancer.

Lancet Oncol 2017 04 24;18(4):428-429. Epub 2017 Feb 24.

Magee-Womens Hospital of the University of Pittsburgh Medical Center, Pittsburgh, PA 15241, USA. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(17)30150-XDOI Listing
April 2017

-Paclitaxel for the treatment of breast cancer: an update across treatment settings.

Authors:
Adam Brufsky

Exp Hematol Oncol 2017 22;6. Epub 2017 Mar 22.

Division of Hematology/Oncology, University of Pittsburgh, 300 Halket Street, Suite 4628, Pittsburgh, PA 15213 USA.

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http://dx.doi.org/10.1186/s40164-017-0066-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361712PMC
March 2017

Understanding the Needs of Patients with Metastatic Breast Cancer: Results of the Make Your Dialogue Count Survey.

Breast J 2017 Jan 13;23(1):17-25. Epub 2016 Sep 13.

ProHEALTH Care Associates, LLP, Lake Success, New York.

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http://dx.doi.org/10.1111/tbj.12675DOI Listing
January 2017

Biomarkers for Early-Stage Breast Cancer: Clinical Utility for Extended Adjuvant Treatment Decisions.

J Clin Oncol 2016 11;34(32):3941-3942

Dennis C. Sgroi, Massachusetts General Hospital, Charlestown and Boston, MA; and Adam Brufsky, University of Pittsburgh Medical Center, Pittsburgh, PA.

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http://dx.doi.org/10.1200/JCO.2016.67.2949DOI Listing
November 2016

Intratumor Heterogeneity Affects Gene Expression Profile Test Prognostic Risk Stratification in Early Breast Cancer.

Clin Cancer Res 2016 Nov 16;22(21):5362-5369. Epub 2016 May 16.

Women's Cancer Research Center, Department of Pharmacology and Chemical Biology, University of Pittsburgh Cancer Institute, Magee Womens Research Institute, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-2889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093028PMC
November 2016

Multiparametric Genomic Assays for Breast Cancer: Time for the Next Generation?

Clin Cancer Res 2016 Oct 12;22(20):4963-4965. Epub 2016 Aug 12.

Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania. University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://clincancerres.aacrjournals.org/content/22/20/4963.ful
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http://dx.doi.org/10.1158/1078-0432.CCR-16-1513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154749PMC
October 2016

Risedronate may preserve bone microarchitecture in breast cancer survivors on aromatase inhibitors: A randomized, controlled clinical trial.

Bone 2016 09 24;90:123-6. Epub 2016 Mar 24.

Department of Medicine, University of Pittsburgh, Pittsburgh, PA, United States; Department of Biostatistics, University of Pittsburgh, Pittsburgh, PA, United States.

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http://dx.doi.org/10.1016/j.bone.2016.03.010DOI Listing
September 2016

Is there room for bevacizumab in metastatic breast cancer?

Authors:
Adam Brufsky

Lancet Oncol 2016 09 5;17(9):1175-6. Epub 2016 Aug 5.

Department of Hematology-Oncology, University of Pittsburgh, Pittsburgh, PA 15213, USA. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(16)30295-9DOI Listing
September 2016

Pathways Clinical Decision Support for Appropriate Use of Key Biomarkers.

J Oncol Pract 2016 06 24;12(6):e681-7. Epub 2016 May 24.

UPMC CancerCenter; University of Pittsburgh Cancer Center; and Via Oncology, Pittsburgh, PA

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http://dx.doi.org/10.1200/JOP.2015.010546DOI Listing
June 2016

Polymorphisms in DNA repair and oxidative stress genes associated with pre-treatment cognitive function in breast cancer survivors: an exploratory study.

Springerplus 2016 9;5:422. Epub 2016 Apr 9.

School of Nursing, University of Pittsburgh, 3500 Victoria Street, Pittsburgh, PA 15261 USA ; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, 130 De Soto Street, Pittsburgh, PA 15261 USA.

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http://dx.doi.org/10.1186/s40064-016-2061-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826652PMC
April 2016

Delaying Chemotherapy in the Treatment of Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer.

Authors:
Adam M Brufsky

Clin Med Insights Oncol 2015 30;9:137-47. Epub 2015 Dec 30.

Professor of Medicine, Associate Division Chief of Hematology/Oncology, Medical Director of Women's Cancer Center at Magee-Womens Hospital, Codirector of Comprehensive Breast Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://dx.doi.org/10.4137/CMO.S31586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697769PMC
January 2016

Prospective Validation of a 21-Gene Expression Assay in Breast Cancer.

N Engl J Med 2015 Nov 27;373(21):2005-14. Epub 2015 Sep 27.

From the Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY (J.A.S., D.F.M.); Dana-Farber Cancer Institute, Boston (R.J.G.); Sunnybrook Research Institute, Toronto (K.I.P.) and Juravinski Cancer Center, Hamilton, ON (T.J.W.) - both in Canada; Loyola University Medical Center, Maywood (K.S.A.), and Northwestern University, Chicago (L.I.W., V.G.K.) - both in Illinois; University of Michigan, Ann Arbor (D.F.H.); Virginia Commonwealth University School of Medicine and the Massey Cancer Center, Richmond (C.E.G.); University of North Carolina, Chapel Hill (E.C.D.), Duke University Medical Center, Durham (J.A.O.), Wake Forest University Health Service, Winston-Salem (L.I.W.), and Southeast Clinical Oncology Research Consortium, Goldsboro (J.N.A.) - all in North Carolina; Mayo Clinic, Jacksonville, FL (E.A.P.); University of Maryland School of Medicine, Baltimore (J.A.O.), and National Institutes of Health, Bethesda (J.Z., T.L.) - both in Maryland; Indiana University School of Medicine (S.S.B.) and Indiana University Hospital (G.W.S.) - both in Indianapolis; Vince Lombardi Cancer Clinic, Two Rivers (T.J.S.), and Fox Valley Hematology and Oncology, Appleton (T.F.G.) - both in Wisconsin; Baylor College of Medicine, Houston (M.J.E.), and University of Texas, San Antonio (P.R.) - both in Texas; Washington University, St. Louis (M.J.E.); Allegheny General Hospital (S.P.) and University of Pittsburgh (A.M.B.) - both in Pittsburgh; the Department of Medical Oncology and Breast Center, Yonsei University College of Medicine, Seoul, South Korea (S.P.); Emory University, Atlanta (W.C.W.); Irish Clinical Oncology Research Group, Dublin (M.M.K.); Instituto Nacional de Enfermedades Neoplásicas, Lima, Peru (H.L.G.M.); Cancer Center of Kansas, Wichita (P.S.R.); Vanderbilt University, Nashville (I.A.M.); Rutgers Cancer Institute of New Jersey, New Brunswick (D.L.T.); University of Hawaii Cancer Center, Honolulu (J.L.B.); and Stanford University, Stanford, CA (G.W.S.)

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http://dx.doi.org/10.1056/NEJMoa1510764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701034PMC
November 2015

Expression of high affinity folate receptor in breast cancer brain metastasis.

Oncotarget 2015 Oct;6(30):30327-33

Division of Hematology and Oncology, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.18632/oncotarget.4639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745802PMC
October 2015

Bisphosphonates, bone, and breast cancer recurrence.

Lancet 2015 Oct 23;386(10001):1319-1320. Epub 2015 Jul 23.

University of Pittsburgh Cancer Institute, Magee-Women's Hospital, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1016/S0140-6736(15)61163-1DOI Listing
October 2015

Developing in vitro models of human ductal carcinoma in situ from primary tissue explants.

Breast Cancer Res Treat 2015 Sep 18;153(2):311-21. Epub 2015 Aug 18.

Division of Surgical Oncology, Department of Surgery, University of Pittsburgh School of Medicine, 300 Halket Street, Suite 2601, Pittsburgh, PA, 15217, USA.

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http://dx.doi.org/10.1007/s10549-015-3551-8DOI Listing
September 2015

Managing postmenopausal women with hormone receptor-positive advanced breast cancer who progress on endocrine therapies with inhibitors of the PI3K pathway.

Authors:
Adam M Brufsky

Breast J 2014 Jul-Aug;20(4):347-57. Epub 2014 May 26.

Magee-Women's Hospital, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1111/tbj.12278DOI Listing
July 2015

Prognostic factors and survival of patients with brain metastasis from breast cancer who underwent craniotomy.

Cancer Med 2015 Jul 9;4(7):989-94. Epub 2015 Mar 9.

Division of Hematology and Oncology, University of Pittsburgh Cancer Institute, 5150 Centre Avenue, Pittsburgh, Pennsylvania, 15232.

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http://dx.doi.org/10.1002/cam4.439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529337PMC
July 2015

Some Excitement, Some Disappointment.

Authors:
Adam M Brufsky

Oncology (Williston Park) 2015 Jul;29(7):494-5

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July 2015

Can circulating tumor cells predict resistance in metastatic breast cancer?

Clin Cancer Res 2015 Jun 2;21(11):2421-3. Epub 2015 Feb 2.

Department of Medicine, University of Pittsburgh School of Medicine, University of Pittsburgh Cancer Institute and UPMC CancerCenter, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-2967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694574PMC
June 2015

The effects of Reiki therapy and companionship on quality of life, mood, and symptom distress during chemotherapy.

J Evid Based Complementary Altern Med 2015 Jan 6;20(1):20-7. Epub 2014 Nov 6.

The University of Texas at Arlington, TX, USA

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http://dx.doi.org/10.1177/2156587214556313DOI Listing
January 2015

Bisphosphonates in breast cancer: a triple winner?

Oncology (Williston Park) 2015 Jan;29(1):37-9

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January 2015

Bisphosphonates do not reduce breast cancer in postmenopausal women.

Ann Intern Med 2015 Jan;162(2):JC5

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http://dx.doi.org/10.7326/ACPJC-2015-162-2-005DOI Listing
January 2015

Length of chemotherapy and use of bevacizumab for breast cancer.

Authors:
Adam Brufsky

Lancet Oncol 2014 Nov 26;15(12):1285-7. Epub 2014 Oct 26.

University of Pittsburgh, 300 Halket Street, Suite 4628, Pittsburgh, PA 15241, USA. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(14)70480-2DOI Listing
November 2014

The use of adjuvant bisphophonates in the treatment of early-stage breast cancer.

Clin Adv Hematol Oncol 2014 Nov;12(11):749-56

University of Pittsburgh Medical Center, Pittsburgh, PA.

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November 2014

Breast cancer: Zoledronic acid--more than just a bone drug.

Nat Rev Clin Oncol 2014 Oct 9;11(10):564-5. Epub 2014 Sep 9.

University of Pittsburgh Cancer Institute, UPMC Cancer Pavilion, 5150 Center Avenue, Pittsburgh, PA 15232, USA.

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http://www.nature.com/articles/nrclinonc.2014.152
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http://dx.doi.org/10.1038/nrclinonc.2014.152DOI Listing
October 2014

Predictive and prognostic value of the 21-gene recurrence score in hormone receptor-positive, node-positive breast cancer.

Authors:
Adam M Brufsky

Am J Clin Oncol 2014 Aug;37(4):404-10

Division of Hematology/Oncology, University of Pittsburgh Cancer Center, Pittsburgh, PA.

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http://dx.doi.org/10.1097/COC.0000000000000086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162320PMC
August 2014

Current Approaches and Emerging Directions in HER2-resistant Breast Cancer.

Authors:
Adam M Brufsky

Breast Cancer (Auckl) 2014 29;8:109-18. Epub 2014 Jul 29.

Women's Cancer Center at Magee-Women's Hospital, University of Pittsburgh School of Medicine, Magee-Women's Hospital, Pittsburgh, PA, USA. ; Comprehensive Breast Cancer Center, University of Pittsburgh School of Medicine, Magee-Women's Hospital, Pittsburgh, PA, USA.

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http://dx.doi.org/10.4137/BCBCR.S9453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125367PMC
August 2014