Adam Bass

Adam Bass

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Adam Bass

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Colorectal adenocarcinoma-derived EGFR mutants are oncogenic and sensitive to EGFR-targeted monoclonal antibodies, cetuximab and panitumumab.

Int J Cancer 2020 Apr 9;146(8):2194-2200. Epub 2019 Jul 9.

Department of Nanobiomedical Science, Dankook University, Cheonan, Republic of Korea.

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http://dx.doi.org/10.1002/ijc.32499DOI Listing
April 2020

Genomics and Targeted Therapies in Gastroesophageal Adenocarcinoma.

Cancer Discov 2019 Dec 14;9(12):1656-1672. Epub 2019 Nov 14.

Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/2159-8290.CD-19-0487DOI Listing
December 2019

Targeting glutamine-addiction and overcoming CDK4/6 inhibitor resistance in human esophageal squamous cell carcinoma.

Nat Commun 2019 03 21;10(1):1296. Epub 2019 Mar 21.

Department of Biochemistry and Molecular Biology, Hollings Cancer Center, Medical University of South Carolina, Charleston, SC, 29425, USA.

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http://dx.doi.org/10.1038/s41467-019-09179-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428878PMC
March 2019

Detection of Mutations in Barrett's Esophagus Before Progression to High-Grade Dysplasia or Adenocarcinoma.

Gastroenterology 2018 07 31;155(1):156-167. Epub 2018 Mar 31.

Eli and Edythe L. Broad Institute, Cambridge, Massachusetts; Department of Molecular Oncology, Dana Farber Cancer Institute, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2018.03.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035092PMC
July 2018

Comparative transcriptomes of adenocarcinomas and squamous cell carcinomas reveal molecular similarities that span classical anatomic boundaries.

PLoS Genet 2017 Aug 7;13(8):e1006938. Epub 2017 Aug 7.

Department of Medicine, Division of Gastroenterology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006938DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560753PMC
August 2017

The effect of white coats and gender on medical students' perceptions of physicians.

BMC Med Educ 2017 May 26;17(1):93. Epub 2017 May 26.

Department of Medicine, University of Calgary, 1403 29th Street NW, Calgary, AB, T2N 2T9, Canada.

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http://dx.doi.org/10.1186/s12909-017-0932-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446716PMC
May 2017

Gastric Adenocarcinoma: An Update on Genomics, Immune System Modulations, and Targeted Therapy.

Am Soc Clin Oncol Educ Book 2016 ;35:104-11

From the Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Kangnamgu, Seoul, South Korea; Division of Molecular and Cellular Oncology, Dana-Farber Cancer Institute, Boston, MA; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.1200/EDBK_159091DOI Listing
January 2017

Sox2 Suppresses Gastric Tumorigenesis in Mice.

Cell Rep 2016 08 4;16(7):1929-41. Epub 2016 Aug 4.

Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA; Howard Hughes Medical Institute and Department of Stem Cell and Regenerative Biology, 7 Divinity Avenue, Harvard University, Cambridge, MA 02138, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.07.034DOI Listing
August 2016

Validation and calibration of next-generation sequencing to identify Epstein-Barr virus-positive gastric cancer in The Cancer Genome Atlas.

Gastric Cancer 2016 Apr 23;19(2):676-681. Epub 2015 Jun 23.

Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1007/s10120-015-0508-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689675PMC
April 2016

Oesophageal adenocarcinoma and gastric cancer: should we mind the gap?

Nat Rev Cancer 2016 04;16(5):305-18

Division of Digestive and Liver Diseases and Herbert Irving Cancer Research Center, Columbia University College of Physicians and Surgeons, 1130 St Nicholas Avenue, New York, New York 10032, USA.

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http://dx.doi.org/10.1038/nrc.2016.24DOI Listing
April 2016

FBXO4 loss facilitates carcinogen induced papilloma development in mice.

Cancer Biol Ther 2015 ;16(5):750-5

a Institute for Regenerative Medicine; University of Pennsylvania School of Medicine ; Philadelphia , PA , USA.

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http://dx.doi.org/10.1080/15384047.2015.1026512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622573PMC
March 2016

MicroRNA MIR21 and T Cells in Colorectal Cancer.

Cancer Immunol Res 2016 Jan 29;4(1):33-40. Epub 2015 Sep 29.

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts. Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts. Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/2326-6066.CIR-15-0084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703429PMC
January 2016

Hitting the Target in BRAF-Mutant Colorectal Cancer.

J Clin Oncol 2015 Dec 12;33(34):3990-2. Epub 2015 Oct 12.

Dana-Farber Cancer Institute, Harvard Medical School, Boston; and Broad Institute of the Massachusetts Institute of Technology and Harvard, Cambridge, MA

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http://dx.doi.org/10.1200/JCO.2015.63.7793DOI Listing
December 2015

SOX15 governs transcription in human stratified epithelia and a subset of esophageal adenocarcinomas.

Cell Mol Gastroenterol Hepatol 2015 Nov;1(6):598-609.e6

Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA ; Department of Medicine, Harvard Medical School, 45 Shattuck Street, Boston, MA 02115, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S2352345X150014
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http://dx.doi.org/10.1016/j.jcmgh.2015.07.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620585PMC
November 2015

Experienced physicians benefit from analyzing initial diagnostic hypotheses.

Can Med Educ J 2013 31;4(1):e7-e15. Epub 2013 Mar 31.

University of Calgary, Calgary, Alberta, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563663PMC
October 2015

ERBB2 emerges as a new target for colorectal cancer.

Cancer Discov 2015 Aug;5(8):799-801

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts. Broad Institute of MIT and Harvard, Cambridge, Massachusetts. Departments of Medicine, Brigham & Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/2159-8290.CD-15-0730DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527096PMC
August 2015

Src mutation induces acquired lapatinib resistance in ERBB2-amplified human gastroesophageal adenocarcinoma models.

PLoS One 2014 28;9(10):e109440. Epub 2014 Oct 28.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America; Cancer Program, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America; Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0109440PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211679PMC
June 2015

Genetic and Epigenetic Alterations in Barrett's Esophagus and Esophageal Adenocarcinoma.

Gastroenterol Clin North Am 2015 Jun 1;44(2):473-89. Epub 2015 Apr 1.

Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.

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http://dx.doi.org/10.1016/j.gtc.2015.02.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449457PMC
June 2015

Dynamic epigenetic regulation by menin during pancreatic islet tumor formation.

Mol Cancer Res 2015 Apr 23;13(4):689-98. Epub 2014 Dec 23.

Department of Medical Oncology, Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Boston, Massachusetts. Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts. Cancer program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts.

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http://dx.doi.org/10.1158/1541-7786.MCR-14-0457DOI Listing
April 2015

Mutational signatures in Helicobacter pylori-induced gastric cancer: lessons from new sequencing technologies.

Gastroenterology 2014 Aug 25;147(2):267-9. Epub 2014 Jun 25.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts and Cancer Program, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2014.06.019DOI Listing
August 2014

Comparison of cancer-associated genetic abnormalities in columnar-lined esophagus tissues with and without goblet cells.

Ann Surg 2014 Jul;260(1):72-80

*Departments of Surgery ‡Pathology, and ‖Biostatistics, University of Rochester Medical Center, Strong Memorial Hospital, Rochester, NY †Life Technologies, Foster City, CA **Dana Farber Cancer Center, Boston, MA ††University of Michigan, Ann Arbor, MI ¶University of Pittsburgh, Pittsburgh, PA; and §Department of Surgery, Boston University, Boston, MA.

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http://dx.doi.org/10.1097/SLA.0000000000000424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047149PMC
July 2014

Managing advanced colorectal cancer: have we reached the PEAK with current therapies?

J Clin Oncol 2014 Jul 16;32(21):2200-2. Epub 2014 Jun 16.

Dana-Farber Cancer Institute; Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1200/JCO.2014.55.6316DOI Listing
July 2014

RhoA mutations identified in diffuse gastric cancer.

Cancer Cell 2014 Jul;26(1):9-11

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2014.06.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206186PMC
July 2014

Colorectal cancers from distinct ancestral populations show variations in BRAF mutation frequency.

PLoS One 2013 16;8(9):e74950. Epub 2013 Sep 16.

Center for Cancer Genome Discovery, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America ; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America ; The Broad Institute, Cambridge, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0074950PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774610PMC
May 2014

Loss of Lkb1 and Pten leads to lung squamous cell carcinoma with elevated PD-L1 expression.

Cancer Cell 2014 May 1;25(5):590-604. Epub 2014 May 1.

Department of Medicine, Harvard Medical School, Boston, MA 02115, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Belfer Institute For Applied Cancer Science, Dana-Farber Cancer Institute, Boston, MA 02215, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2014.03.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112370PMC
May 2014

Masking epistasis between MYC and TGF-β pathways in antiangiogenesis-mediated colon cancer suppression.

J Natl Cancer Inst 2014 Apr 13;106(4):dju043. Epub 2014 Mar 13.

Affiliations of authors: Division of Cancer Pathobiology, Center for Childhood Cancer Research (MD, GST, SH, AT-T) and Center for Biomedical Informatics (PR), Children's Hospital of Philadelphia, Philadelphia, PA; Cancer Biology Graduate Program (JC, EKD, AT-T) and Department of Pathology & Laboratory Medicine (AT-T), Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Division of Experimental Pathology, Beth Israel Deaconess Medical Center (JL) and Department of Medical Oncology, Dana-Farber Cancer Institute (AB), Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1093/jnci/dju043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982891PMC
April 2014

Canadian Society of Nephrology commentary on the 2012 KDIGO Clinical Practice Guideline for Anemia in CKD.

Am J Kidney Dis 2013 Nov 17;62(5):860-73. Epub 2013 Sep 17.

Department of Medicine and Epidemiology, Kidney Clinical Research Unit Western University, London, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1053/j.ajkd.2013.08.001DOI Listing
November 2013

A common p53 mutation (R175H) activates c-Met receptor tyrosine kinase to enhance tumor cell invasion.

Cancer Biol Ther 2013 Sep 18;14(9):853-9. Epub 2013 Jun 18.

Gastroenterology Division; Department of Medicine; University of Pennsylvania; Philadelphia, PA USA; Abramson Cancer Center; University of Pennsylvania; Philadelphia, PA USA; Department of Genetics; University of Pennsylvania; Philadelphia, PA USA.

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http://dx.doi.org/10.4161/cbt.25406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909554PMC
September 2013

In-group bias in residency selection.

Med Teach 2013 Sep 27;35(9):747-51. Epub 2013 Jun 27.

University of Calgary, Canada.

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http://dx.doi.org/10.3109/0142159X.2013.801937DOI Listing
September 2013

Mutant N-RAS protects colorectal cancer cells from stress-induced apoptosis and contributes to cancer development and progression.

Cancer Discov 2013 Mar 28;3(3):294-307. Epub 2012 Dec 28.

Molecular Pathology Unit, Center for Cancer Research and Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Charlestown 02129 , USA.

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http://dx.doi.org/10.1158/2159-8290.CD-12-0198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595397PMC
March 2013

An inflammatory situation: SOX2 and STAT3 cooperate in squamous cell carcinoma initiation.

Cell Stem Cell 2013 Mar;12(3):266-8

Division of Molecular and Cellular Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.

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http://dx.doi.org/10.1016/j.stem.2013.02.004DOI Listing
March 2013

The impact of nocturnal hemodialysis on sexual function.

BMC Nephrol 2012 Jul 26;13:67. Epub 2012 Jul 26.

Department of Medicine, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1186/1471-2369-13-67DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457870PMC
July 2012

Comparative genomics of esophageal adenocarcinoma and squamous cell carcinoma.

Ann Thorac Surg 2012 Apr;93(4):1101-6

Department of Surgery, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642-8410, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00034975120017
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http://dx.doi.org/10.1016/j.athoracsur.2012.01.064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401935PMC
April 2012

Activation of GATA binding protein 6 (GATA6) sustains oncogenic lineage-survival in esophageal adenocarcinoma.

Proc Natl Acad Sci U S A 2012 Mar 28;109(11):4251-6. Epub 2012 Feb 28.

Department of Surgery, Department of Pathology, and Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1073/pnas.1011989109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306720PMC
March 2012

Abnormalities of lexical and semantic processing in left temporal lobe epilepsy: an fMRI study.

Epilepsia 2011 Nov 11;52(11):2013-21. Epub 2011 Sep 11.

Department of Neuroscience, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1111/j.1528-1167.2011.03258.xDOI Listing
November 2011

Impact of KRAS and BRAF gene mutations on targeted therapies in colorectal cancer.

Authors:
Adam Bass

J Clin Oncol 2011 Jul 6;29(19):2728-9. Epub 2011 Jun 6.

Dana-Farber Cancer Institute, Boston, MA, USA.

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http://dx.doi.org/10.1200/JCO.2011.36.1816DOI Listing
July 2011

Cortical reorganization and reduced efficiency of visual word recognition in right temporal lobe epilepsy: a functional MRI study.

Epilepsy Res 2011 Feb 6;93(2-3):155-63. Epub 2011 Jan 6.

Department of Neuroscience, University of Calgary, Canada.

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http://dx.doi.org/10.1016/j.eplepsyres.2010.12.003DOI Listing
February 2011

Decreased selenium-binding protein 1 in esophageal adenocarcinoma results from posttranscriptional and epigenetic regulation and affects chemosensitivity.

Clin Cancer Res 2010 Apr 23;16(7):2009-21. Epub 2010 Mar 23.

Section of Thoracic Surgery, Department of Surgery and Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-09-2801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2953959PMC
April 2010

Genome-wide association study in esophageal squamous cell carcinoma.

Gastroenterology 2009 Nov 27;137(5):1573-6. Epub 2009 Sep 27.

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http://dx.doi.org/10.1053/j.gastro.2009.09.026DOI Listing
November 2009