Publications by authors named "Ad Geurts van Kessel"

97Publications

NTHL1 and MUTYH polyposis syndromes: two sides of the same coin?

J Pathol 2018 02 14;244(2):135-142. Epub 2017 Dec 14.

Department of Human Genetics, Radboud Institute for Molecular Life Sciences, Radboud university medical center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/path.5002DOI Listing
February 2018

Prevalence of germline mutations in the spindle assembly checkpoint gene BUB1B in individuals with early-onset colorectal cancer.

Genes Chromosomes Cancer 2016 11 7;55(11):855-63. Epub 2016 Jul 7.

Department of Human Genetics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/gcc.22385DOI Listing
November 2016

Candidate colorectal cancer predisposing gene variants in Chinese early-onset and familial cases.

World J Gastroenterol 2015 Apr;21(14):4136-49

Jun-Xiao Zhang, Richarda M de Voer, Marc-Manuel Hahn, Eugène TP Verwiel, Marjolijn JL Ligtenberg, Nicoline Hoogerbrugge, Roland P Kuiper, Ad Geurts van Kessel, Department of Human Genetics, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.3748/wjg.v21.i14.4136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394074PMC
April 2015

Perivascular epithelioid cell tumor of gastrointestinal tract: case report and review of the literature.

Medicine (Baltimore) 2015 Jan;94(3):e393

From the Guangdong Institute of Gastroenterology and the Sixth Affiliated Hospital, (BL, CW, JZ, MS, XZ, SS, JW, HL); Guangdong Key Laboratory of Colorectal and Pelvic Floor Diseases, (BL, CW, JZ, MS, XZ, JW, HL); Institute of Human Virology, (BL, CW, JZ, MS, XZ, HL) Key Laboratory of Tropical Disease Control (Ministry of Education); Sun Yat-sen University, Guangzhou (BL, CW, JZ, MS, XZ, HL); Dongguan Health School, Dongguan, China (BL); Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands (JZ, RPK, AGK); and Advanced Clinical Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan (AI).

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http://dx.doi.org/10.1097/MD.0000000000000393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602642PMC
January 2015

The cancer genome: from structure to function.

Cell Oncol (Dordr) 2014 Jun;37(3):155-65

Department of Human Genetics 855, Radboud University Medical Center, PO. Box 9101, 6500, HB, Nijmegen, The Netherlands,

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http://dx.doi.org/10.1007/s13402-014-0177-5DOI Listing
June 2014

Detecting fetal subchromosomal aberrations by MPS: an unexpected discrepancy between amniocyte DNA and ccffDNA.

Prenat Diagn 2014 Apr 6;34(4):402-5. Epub 2014 Feb 6.

Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1002/pd.4312DOI Listing
April 2014

EPCAM deletion carriers constitute a unique subgroup of Lynch syndrome patients.

Fam Cancer 2013 Jun;12(2):169-74

Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s10689-012-9591-xDOI Listing
June 2013

Identification of CUX1 as the recurrent chromosomal band 7q22 target gene in human uterine leiomyoma.

Genes Chromosomes Cancer 2013 Jan 10;52(1):11-23. Epub 2012 Sep 10.

Department of Human Genetics, Radboud University Nijmegen Medical Centre and Nijmegen Centre for Molecular Life Sciences, Nijmegen, The Netherlands.

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http://www.corpuscallosum.org.au/Jens_Bunt_files/Genes%20Chr
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http://doi.wiley.com/10.1002/gcc.22001
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http://dx.doi.org/10.1002/gcc.22001DOI Listing
January 2013

High detection rate of clinically relevant genomic abnormalities in plasma cells enriched from patients with multiple myeloma.

Genes Chromosomes Cancer 2012 Nov 25;51(11):997-1006. Epub 2012 Jul 25.

Department of Human Genetics, Radboud University Nijmegen Medical Centre, The Netherlands.

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http://dx.doi.org/10.1002/gcc.21982DOI Listing
November 2012

New insights and clinical advancements in cellular oncology.

Cell Oncol (Dordr) 2012 Jun;35(3):139-47

Department of Human Genetics 855, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1007/s13402-012-0083-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396341PMC
June 2012

Non-invasive prenatal diagnosis of fetal aneuploidies using massively parallel sequencing-by-ligation and evidence that cell-free fetal DNA in the maternal plasma originates from cytotrophoblastic cells.

Expert Opin Biol Ther 2012 Jun 16;12 Suppl 1:S19-26. Epub 2012 Apr 16.

Radboud University Nijmegen Medical Centre, Department of Human Genetics, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1517/14712598.2012.670632DOI Listing
June 2012

Microarray-based genomic profiling as a diagnostic tool in acute lymphoblastic leukemia.

Genes Chromosomes Cancer 2011 Dec 31;50(12):969-81. Epub 2011 Aug 31.

Department of Human Genetics, Radboud University Nijmegen Medical Centre, Radboud University Centre for Oncology, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/gcc.20919DOI Listing
December 2011

Genomic profiling of papillary renal cell tumours identifies small regions of DNA alterations: a possible role of HNF1B in tumour development.

Histopathology 2011 May 25;58(6):934-43. Epub 2011 Mar 25.

Laboratory of Molecular Oncology, Medical Faculty, Ruprecht-Karls-University, Heidelberg, Germany.

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http://dx.doi.org/10.1111/j.1365-2559.2011.03795.xDOI Listing
May 2011

The mitotic arrest deficient protein MAD2B interacts with the clathrin light chain A during mitosis.

PLoS One 2010 Nov 30;5(11):e15128. Epub 2010 Nov 30.

Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen Centre for Molecular Life Sciences, Nijmegen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0015128PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994903PMC
November 2010

The 'omics' of cancer.

Cancer Genet Cytogenet 2010 Nov;203(1):37-42

Department of Human Genetics, Radboud University Nijmegen Medical Center, Nijmegen Center for Molecular Life Sciences, Radboud University Center for Oncology, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.cancergencyto.2010.08.023DOI Listing
November 2010

The epigenetics of (hereditary) colorectal cancer.

Cancer Genet Cytogenet 2010 Nov;203(1):1-6

Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Centre for Oncology, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.cancergencyto.2010.08.013DOI Listing
November 2010

Germline copy number variation and cancer risk.

Curr Opin Genet Dev 2010 Jun 8;20(3):282-9. Epub 2010 Apr 8.

Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen Centre for Molecular Life Sciences, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.gde.2010.03.005DOI Listing
June 2010

BTG1 regulates glucocorticoid receptor autoinduction in acute lymphoblastic leukemia.

Blood 2010 Jun 30;115(23):4810-9. Epub 2010 Mar 30.

Department of Pediatrics, Laboratory of Pediatric Oncology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://www.bloodjournal.org/content/115/23/4810.full.pdf
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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2009-05-22
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http://dx.doi.org/10.1182/blood-2009-05-223081DOI Listing
June 2010

X chromosome inactivation does not define the development of premature ovarian failure in fragile X premutation carriers.

Am J Med Genet A 2010 Feb;152A(2):387-93

Department of Obstetrics and Gynecology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/ajmg.a.33243DOI Listing
February 2010

Identification of chromosomal abnormalities relevant to prognosis in chronic lymphocytic leukemia using multiplex ligation-dependent probe amplification.

Cancer Genet Cytogenet 2009 Dec;195(2):97-104

Department of Human Genetics, Radboud University Nijmegen Medical Center, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.cancergencyto.2009.06.020DOI Listing
December 2009

The mitotic arrest deficient protein MAD2B interacts with the small GTPase RAN throughout the cell cycle.

PLoS One 2009 Sep 15;4(9):e7020. Epub 2009 Sep 15.

Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen Centre for Molecular Life Sciences, Nijmegen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0007020PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737141PMC
September 2009

Characterization of a recurrent t(1;2)(p36;p24) in human uterine leiomyoma.

Cancer Genet Cytogenet 2009 Aug;193(1):54-62

Department of Human Genetics, Radboud University Nijmegen Medical Center, and Nijmegen Center for Molecular Life Sciences, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S01654608090018
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http://dx.doi.org/10.1016/j.cancergencyto.2009.03.011DOI Listing
August 2009

Acquired mutations in TET2 are common in myelodysplastic syndromes.

Nat Genet 2009 Jul 31;41(7):838-42. Epub 2009 May 31.

Department of Hematology and Central Hematology Laboratory, Radboud University Nijmegen Medical Centre and Nijmegen Centre for Molecular Life Sciences, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/ng.391DOI Listing
July 2009

The renal cell carcinoma-associated oncogenic fusion protein PRCCTFE3 provokes p21 WAF1/CIP1-mediated cell cycle delay.

Exp Cell Res 2009 Aug 5;315(14):2399-409. Epub 2009 May 5.

Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen Centre for Molecular Life Sciences, Nijmegen, The Netherlands.

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http://linkinghub.elsevier.com/retrieve/pii/S001448270900191
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http://dx.doi.org/10.1016/j.yexcr.2009.04.022DOI Listing
August 2009

Genomic microarrays in mental retardation: a practical workflow for diagnostic applications.

Hum Mutat 2009 Mar;30(3):283-92

Department of Human Genetics, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://doi.wiley.com/10.1002/humu.20883
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http://dx.doi.org/10.1002/humu.20883DOI Listing
March 2009

Recurrent CNVs disrupt three candidate genes in schizophrenia patients.

Am J Hum Genet 2008 Oct;83(4):504-10

Department of Human Genetics, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.ajhg.2008.09.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2561936PMC
October 2008

Mapping of constitutional translocation breakpoints in renal cell cancer patients: identification of KCNIP4 as a candidate gene.

Cancer Genet Cytogenet 2007 Nov;179(1):11-8

Department of Human Genetics, Radboud University Nijmegen Medical Centre and Nijmegen Centre for Molecular Life Sciences, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.cancergencyto.2007.07.005DOI Listing
November 2007

Genotype-phenotype mapping of chromosome 18q deletions by high-resolution array CGH: an update of the phenotypic map.

Am J Med Genet A 2007 Aug;143A(16):1858-67

Department of Human Genetics, University Medical Centre Nijmegen, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/ajmg.a.31850DOI Listing
August 2007

The (epi)genetics of human synovial sarcoma.

Genes Chromosomes Cancer 2007 Feb;46(2):107-17

Department of Human Genetics, Radboud University Nijmegen Medical Center, Nijmegen Center for Molecular Life Sciences, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/gcc.20399DOI Listing
February 2007

The synovial-sarcoma-associated SS18-SSX2 fusion protein induces epigenetic gene (de)regulation.

Cancer Res 2006 Oct;66(19):9474-82

Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-3726DOI Listing
October 2006

Holoprosencephaly and preaxial polydactyly associated with a 1.24 Mb duplication encompassing FBXW11 at 5q35.1.

J Hum Genet 2006 25;51(8):721-726. Epub 2006 Jul 25.

Department of Human Genetics, Radboud University Nijmegen Medical Centre, 9101, 6500 HB, Nijmegen, The Netherlands.

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http://www.nature.com/doifinder/10.1007/s10038-006-0010-8
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http://dx.doi.org/10.1007/s10038-006-0010-8DOI Listing
October 2006

Identification of disease genes by whole genome CGH arrays.

Hum Mol Genet 2005 Oct;14 Spec No. 2:R215-23

Department of Human Genetics, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, PO Box 9101 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/hmg/ddi268DOI Listing
October 2005

Identification of androgen-responsive genes that are alternatively regulated in androgen-dependent and androgen-independent rat prostate tumors.

Genes Chromosomes Cancer 2005 Jul;43(3):273-83

Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/gcc.20184DOI Listing
July 2005

Chromosome 3 translocations and familial renal cell cancer.

Curr Mol Med 2004 Dec;4(8):849-54

Department of Human Genetics and Hereditary Cancer Clinic, University Medical Center Nijmegen, Nijmegen, The Netherlands.

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http://dx.doi.org/10.2174/1566524043359593DOI Listing
December 2004

Novel chromosomal imbalances in mantle cell lymphoma detected by genome-wide array-based comparative genomic hybridization.

Blood 2005 Feb 21;105(4):1686-93. Epub 2004 Oct 21.

Department of Pathology, University Medical Centre Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1182/blood-2004-07-2730DOI Listing
February 2005

Mutations in a new member of the chromodomain gene family cause CHARGE syndrome.

Nat Genet 2004 Sep 8;36(9):955-7. Epub 2004 Aug 8.

Department of Human Genetics, University Medical Center Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/ng1407DOI Listing
September 2004

Regulation of the MiTF/TFE bHLH-LZ transcription factors through restricted spatial expression and alternative splicing of functional domains.

Nucleic Acids Res 2004 26;32(8):2315-22. Epub 2004 Apr 26.

Department of Human Genetics, University Medical Center Nijmegen, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/nar/gkh571DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC419459PMC
May 2004

Loss of a small region around the PTEN locus is a major chromosome 10 alteration in prostate cancer xenografts and cell lines.

Genes Chromosomes Cancer 2004 Mar;39(3):171-84

Department of Pathology, Josephine Nefkens Institute, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://doi.wiley.com/10.1002/gcc.10311
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http://dx.doi.org/10.1002/gcc.10311DOI Listing
March 2004

Chromosomal breakpoint mapping by arrayCGH using flow-sorted chromosomes.

Biotechniques 2003 Nov;35(5):1066-70

Department of Human Genetics, 417, University Medical Center Nijmegen, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://www.biotechniques.com/multimedia/archive/00010/03355d
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http://dx.doi.org/10.2144/03355dd03DOI Listing
November 2003

12p-amplicon structure analysis in testicular germ cell tumors of adolescents and adults by array CGH.

Oncogene 2003 Oct;22(48):7695-701

Pathology/Laboratory for Exp. Patho-Oncology, Erasmus MC-Erasmus University Medical Center/Daniel den Hoed Cancer Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/sj.onc.1207011DOI Listing
October 2003

Disruption of a novel gene, DIRC3, and expression of DIRC3-HSPBAP1 fusion transcripts in a case of familial renal cell cancer and t(2;3)(q35;q21).

Genes Chromosomes Cancer 2003 Oct;38(2):107-16

Department of Human Genetics, University Medical Center Nijmegen, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/gcc.10243DOI Listing
October 2003

Upregulation of the transcription factor TFEB in t(6;11)(p21;q13)-positive renal cell carcinomas due to promoter substitution.

Hum Mol Genet 2003 Jul;12(14):1661-9

Department of Human Genetics, University Medical Center Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/hmg/ddg178DOI Listing
July 2003

Germ cell tumours in neonates and infants: a distinct subgroup?

APMIS 2003 Jan;111(1):152-60; discussion 160

Department of Human Genetics, University Medical Center Nijmegen, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1034/j.1600-0463.2003.1110119_1.xDOI Listing
January 2003

Understanding familial and non-familial renal cell cancer.

Hum Mol Genet 2002 Oct;11(20):2489-98

Department of Human Genetics, University Medical Center Nijmegen, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/hmg/11.20.2489DOI Listing
October 2002

Molecular cytogenetic analysis of clustered sporadic and familial renal cell carcinoma-associated 3q13 approximately q22 breakpoints.

Cancer Genet Cytogenet 2002 Jul;136(2):95-100

Department of Human Genetics, University Medical Center Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/s0165-4608(02)00517-4DOI Listing
July 2002