Abou-Donia M

Abou-Donia M

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Abou-Donia M

Abou-Donia M

Publications by authors named "Abou-Donia M"

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1PubMed Central Citations

Blood Biomarkers in Autism: Autoantibodies against Neuronal and Glial Proteins.

Behav Sci (Basel) 2019 Apr 29;9(5). Epub 2019 Apr 29.

Faculty of Science, Shebien El-KoomUniversity 32615 Shebien El-Koom, Egypt.

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http://dx.doi.org/10.3390/bs9050047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563083PMC
April 2019

Tubulin and Tau: Possible targets for diagnosis of Parkinson's and Alzheimer's diseases.

PLoS One 2018 9;13(5):e0196436. Epub 2018 May 9.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0196436PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942772PMC
August 2018

Amyotrophic lateral sclerosis-A case report and mechanistic review of the association with toluene and other volatile organic compounds.

Am J Ind Med 2018 03 10;61(3):251-260. Epub 2017 Nov 10.

Department of Medicine (Pulmonary and Critical Care Division), Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1002/ajim.22791DOI Listing
March 2018

A Panel of Autoantibodies Against Neural Proteins as Peripheral Biomarker for Pesticide-Induced Neurotoxicity.

Neurotox Res 2018 02 5;33(2):316-336. Epub 2017 Sep 5.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina, 27710, USA.

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http://dx.doi.org/10.1007/s12640-017-9793-yDOI Listing
February 2018

Neural autoantibodies in patients with neurological symptoms and histories of chemical/mold exposures.

Toxicol Ind Health 2018 Jan 25;34(1):44-53. Epub 2017 Oct 25.

2 Center for Occupational and Environmental Medicine, North Charleston, SC, USA.

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http://dx.doi.org/10.1177/0748233717733852DOI Listing
January 2018

Screening for novel central nervous system biomarkers in veterans with Gulf War Illness.

Neurotoxicol Teratol 2017 05 9;61:36-46. Epub 2017 Mar 9.

Biomedical Engineering Department, Duke University, United States.

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http://dx.doi.org/10.1016/j.ntt.2017.03.002DOI Listing
May 2017

Sarin (GB, O-isopropyl methylphosphonofluoridate) neurotoxicity: critical review.

Crit Rev Toxicol 2016 11 5;46(10):845-875. Epub 2016 Oct 5.

a Department of Pharmacology and Cancer Biology , Duke University , Durham , NC , USA.

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http://dx.doi.org/10.1080/10408444.2016.1220916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764759PMC
November 2016

Spectrophotometric analysis of solubilized rat hair proteins following intraperitoneal injection of 2,5-hexanedione.

Toxicol Mech Methods 2002 ;12(4):277-91

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina, USA.

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http://dx.doi.org/10.1080/15376520208951164DOI Listing
October 2012

Sucralose revisited: rebuttal of two papers about Splenda safety.

Regul Toxicol Pharmacol 2012 Aug 9;63(3):505-8; author reply 509-13. Epub 2012 May 9.

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http://dx.doi.org/10.1016/j.yrtph.2012.05.002DOI Listing
August 2012

Early differential cell death and survival mechanisms initiate and contribute to the development of OPIDN: a study of molecular, cellular, and anatomical parameters.

Toxicol Appl Pharmacol 2011 Nov 5;256(3):348-59. Epub 2011 Aug 5.

Dept of Medicine, Duke University Medical Center, Durham, NC, USA.

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http://dx.doi.org/10.1016/j.taap.2011.07.017DOI Listing
November 2011

DFP initiated early alterations of PKA/p-CREB pathway and differential persistence of beta-tubulin subtypes in the CNS of hens contributes to OPIDN.

Toxicol Appl Pharmacol 2009 Oct 5;240(2):132-42. Epub 2009 Aug 5.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/j.taap.2009.07.035DOI Listing
October 2009

Splenda alters gut microflora and increases intestinal p-glycoprotein and cytochrome p-450 in male rats.

J Toxicol Environ Health A 2008 ;71(21):1415-29

Department of Pharmacology, Duke University Medical Center, Durham, North Carolina 27708, USA.

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http://dx.doi.org/10.1080/15287390802328630DOI Listing
October 2008

In vitro metabolism and interactions of pyridostigmine bromide, N,N-diethyl-m-toluamide, and permethrin in human plasma and liver microsomal enzymes.

Xenobiotica 2008 Mar;38(3):294-313

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1080/00498250701813230 DOI Listing
March 2008

In utero exposure to nicotine and chlorpyrifos alone, and in combination produces persistent sensorimotor deficits and Purkinje neuron loss in the cerebellum of adult offspring rats.

Arch Toxicol 2006 Sep 16;80(9):620-31. Epub 2006 Feb 16.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1007/s00204-006-0077-1DOI Listing
September 2006

Interaction of pyridostigmine bromide and N,N-diethyl-m-toluamide alone and in combination with P-glycoprotein expressed in Escherichia coli leaky mutant.

J Toxicol Environ Health A 2006 May;69(10):919-33

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1080/15287390500360588DOI Listing
May 2006

Toxicogenomic studies of the rat brain at an early time point following acute sarin exposure.

Neurochem Res 2006 Mar 13;31(3):367-81. Epub 2006 May 13.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, P.O. Box 3813, Durham, NC, 27710, USA.

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http://dx.doi.org/10.1007/s11064-005-9023-5DOI Listing
March 2006

Gene expression profiles of the rat brain both immediately and 3 months following acute sarin exposure.

Biochem Pharmacol 2006 Feb 27;71(4):497-520. Epub 2005 Dec 27.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/j.bcp.2005.10.051DOI Listing
February 2006

Antimuscarinic drugs for overactive bladder and their potential effects on cognitive function in older patients.

J Am Geriatr Soc 2005 Dec;53(12):2195-201

Neuropsychology Division, Department of Neurology, Georgetown University School of Medicine, Washington, DC, USA.

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http://dx.doi.org/10.1111/j.1532-5415.2005.00537.xDOI Listing
December 2005

Cholestyramine feeding lowers number of colonic apoptotic cells in rat.

J Toxicol Environ Health A 2005 Nov;68(22):1963-75

Department of Pharmacology, Cancer Biology, Durham, North Carolina, USA.

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http://dx.doi.org/10.1080/15287390500227050DOI Listing
November 2005

Depleted and natural uranium: chemistry and toxicological effects.

J Toxicol Environ Health B Crit Rev 2004 Jul-Aug;7(4):297-317

Nicholas School of the Environment and Earth Sciences, Duke University, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1080/10937400490452714DOI Listing
July 2004

Neurological deficits induced by malathion, DEET, and permethrin, alone or in combination in adult rats.

J Toxicol Environ Health A 2004 Feb;67(4):331-56

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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February 2004

Co-exposure to pyridostigmine bromide, DEET, and/or permethrin causes sensorimotor deficit and alterations in brain acetylcholinesterase activity.

Pharmacol Biochem Behav 2004 Feb;77(2):253-62

Department of Pharmacology and Cancer Biology, Duke University Medical Center, P.O. Box 3813, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/j.pbb.2003.10.018DOI Listing
February 2004

Stress and combined exposure to low doses of pyridostigmine bromide, DEET, and permethrin produce neurochemical and neuropathological alterations in cerebral cortex, hippocampus, and cerebellum.

J Toxicol Environ Health A 2004 Jan;67(2):163-92

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1080/15287390490264802DOI Listing
January 2004

Increased expression of glial fibrillary acidic protein in cerebellum and hippocampus: differential effects on neonatal brain regional acetylcholinesterase following maternal exposure to combined chlorpyrifos and nicotine.

J Toxicol Environ Health A 2003 Nov;66(21):2047-66

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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November 2003

Sensorimotor deficits and increased brain nicotinic acetylcholine receptors following exposure to chlorpyrifos and/or nicotine in rats.

Arch Toxicol 2003 Aug 26;77(8):452-8. Epub 2003 Apr 26.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1007/s00204-003-0463-xDOI Listing
August 2003

Organophosphorus ester-induced chronic neurotoxicity.

Arch Environ Health 2003 Aug;58(8):484-97

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.3200/AEOH.58.8.484-497DOI Listing
August 2003

Reversal of P-glycoprotein expressed in Escherichia coli leaky mutant by ascorbic acid.

Life Sci 2003 Jul;73(8):981-91

Department of Pharmacology, Duke University Medical Center, Box 3813, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/s0024-3205(03)00376-xDOI Listing
July 2003

Sarin (nerve agent GB)-induced differential expression of mRNA coding for the acetylcholinesterase gene in the rat central nervous system.

Biochem Pharmacol 2003 Jun;65(12):2041-7

Department of Pharmacology and Cancer Biology, Duke University Medical Center, PO Box 3813, Durham, NC 27708, USA.

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http://dx.doi.org/10.1016/s0006-2952(03)00160-6DOI Listing
June 2003

A role for P-glycoprotein in environmental toxicology.

J Toxicol Environ Health B Crit Rev 2003 May-Jun;6(3):279-88

Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1080/10937400306466DOI Listing
May 2003

Methyl parathion: a review of health effects.

J Toxicol Environ Health B Crit Rev 2003 Mar-Apr;6(2):185-210

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1080/10937400306471DOI Listing
March 2003

Combined exposure to DEET (N,N-diethyl-m-toluamide) and permethrin: pharmacokinetics and toxicological effects.

J Toxicol Environ Health B Crit Rev 2003 Jan-Feb;6(1):41-53

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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March 2003

Testicular germ-cell apoptosis in stressed rats following combined exposure to pyridostigmine bromide, N,N-diethyl m-toluamide (DEET), and permethrin.

J Toxicol Environ Health A 2003 Jan;66(1):57-73

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina, USA.

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http://dx.doi.org/10.1080/15287390306463DOI Listing
January 2003

Acute exposure to sarin increases blood brain barrier permeability and induces neuropathological changes in the rat brain: dose-response relationships.

Neuroscience 2002 ;113(3):721-41

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/s0306-4522(02)00176-8DOI Listing
November 2002

Depleted uranium--the growing concern.

J Appl Toxicol 2002 May-Jun;22(3):149-52

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1002/jat.841DOI Listing
October 2002

Sarin: health effects, metabolism, and methods of analysis.

Food Chem Toxicol 2002 Oct;40(10):1327-33

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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October 2002

Pharmacokinetic profile and placental transfer of a single intravenous injection of [(14)C]chlorpyrifos in pregnant rats.

Arch Toxicol 2002 Aug 13;76(8):452-9. Epub 2002 Jun 13.

Department of Pharmacology and Cancer Biology, Box 3813, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1007/s00204-002-0366-2DOI Listing
August 2002

Disruption of the blood-brain barrier and neuronal cell death in cingulate cortex, dentate gyrus, thalamus, and hypothalamus in a rat model of Gulf-War syndrome.

Neurobiol Dis 2002 Aug;10(3):306-26

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Caroloina 277109, USA.

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August 2002

Uranyl acetate-induced sensorimotor deficit and increased nitric oxide generation in the central nervous system in rats.

Pharmacol Biochem Behav 2002 Jul;72(4):881-90

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/s0091-3057(02)00772-4DOI Listing
July 2002

Binding of pyridostigmine bromide, N,N-diethyl-m-toluamide and permethrin, alone and in combinations, to human serum albumin.

Arch Toxicol 2002 May 9;76(4):203-8. Epub 2002 Mar 9.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1007/s00204-002-0328-8DOI Listing
May 2002

Differential alteration of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA in the central nervous system of hens treated with diisopropylphosphorofluoridate (DFP).

Neurochem Int 2002 Apr;40(4):371-9

Department of Pharmacology and Cancer Biology, Duke University Medical Center, P.O. Box 3813, Durham, NC 27708, USA.

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April 2002

Sensorimotor deficit and cholinergic changes following coexposure with pyridostigmine bromide and sarin in rats.

Toxicol Sci 2002 Mar;66(1):148-58

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1093/toxsci/66.1.148DOI Listing
March 2002

Sarin causes altered time course of mRNA expression of alpha tubulin in the central nervous system of rats.

Neurochem Res 2002 Mar;27(3):177-81

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27708, USA.

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March 2002

Inhibition and recovery of maternal and fetal cholinesterase enzymes following a single oral dose of chlorpyrifos in rats.

Arch Toxicol 2002 Feb 18;76(1):30-9. Epub 2001 Dec 18.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1007/s00204-001-0314-6DOI Listing
February 2002

Protein levels of neurofilament subunits in the hen central nervous system following prevention and potentiation of diisopropyl phosphorofluoridate (DFP)-induced delayed neurotoxicity(1).

Biochem Pharmacol 2002 Jan;63(1):11-9

Neurotoxicology Laboratory, School of Life Science, University of Science and Technology of China, 230027, Hefei, Anhui, P. R. China.

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http://dx.doi.org/10.1016/s0006-2952(01)00858-9DOI Listing
January 2002

Inhibition and recovery of maternal and fetal cholinesterase enzyme activity following a single cutaneous dose of methyl parathion and diazinon, alone and in combination, in pregnant rats.

J Appl Toxicol 2001 Jul-Aug;21(4):307-16

Department of Pharmacology and Cancer Biology, PO Box 3813, Duke University Medical Center, Durham, NC 27710, USA.

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December 2001

A validated HPLC method for the determination of pyridostigmine bromide, acetaminophen, acetylsalicylic acid and caffeine in rat plasma and urine.

J Pharm Biomed Anal 2001 Dec;26(5-6):939-47

Department of Pharmacology and Cancer Biology, Duke University Medical Center, PO Box 3813, Durham, NC 27710, USA.

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December 2001

Absorption, distribution, metabolism and excretion of daily oral doses of [14C]methyl parathion in hens.

Toxicol Lett 2001 Dec;125(1-3):1-10

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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December 2001

Simultaneous determination of chlorpyrifos, permethrin, and their metabolites in rat plasma and urine by high-performance liquid chromatography.

J Anal Toxicol 2001 May-Jun;25(4):275-9

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1093/jat/25.4.275DOI Listing
November 2001

DEET (N,N-diethyl-m-toluamide) alone and in combination with permethrin increased urinary excretion of 6beta-hydroxycortisol in rats, a marker of hepatic CYP3A induction.

J Toxicol Environ Health A 2001 Nov;64(5):373-84

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1080/152873901753170722DOI Listing
November 2001

A solid phase extraction reversed-phase HPLC method for the simultaneous determination of methoprene, permethrin and selected metabolites in rat plasma and urine.

Biomed Chromatogr 2001 Nov;15(7):464-70

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1002/bmc.97DOI Listing
November 2001

Effects of sub-chronic in vivo chlorpyrifos exposure on muscarinic receptors and adenylate cyclase of rat striatum.

Arch Toxicol 2001 Oct;75(8):480-6

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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October 2001

Effect of prevention and potentiation of diisopropyl phosphorofluoridate (DFP)-induced delayed neurotoxicity on the mRNA expression of neurofilament subunits in hen central nervous system.

Biochem Cell Biol 2001 ;79(2):207-17

Neurotoxicology Laboratory, School of Life Science, University of Science and Technology of China, Hefei, Anhui, P.R. China.

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September 2001

Determination of depleted uranium, pyridostigmine bromide and its metabolite in plasma and urine following combined administration in rats.

J Pharm Biomed Anal 2001 Sep;26(2):281-9

Department of Pharmacology and Cancer Biology, Duke University Medical Center, PO Box 3813, Durham, NC 27710, USA.

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September 2001

Simultaneous determination of malathion, permethrin, DEET (N,N-diethyl-m-toluamide), and their metabolites in rat plasma and urine using high performance liquid chromatography.

J Pharm Biomed Anal 2001 Sep;26(2):291-9

Department of Pharmacology and Cancer Biology, Duke University Medical Center, PO Box 3813, Durham, NC 27710, USA.

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September 2001

Biomarkers of apoptosis: release of cytochrome c, activation of caspase-3, induction of 8-hydroxy-2'-deoxyguanosine, increased 3-nitrotyrosine, and alteration of p53 gene.

J Toxicol Environ Health B Crit Rev 2001 Jul-Sep;4(3):313-32

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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August 2001

Combined exposure to sarin and pyridostigmine bromide increased levels of rat urinary 3-nitrotyrosine and 8-hydroxy-2'-deoxyguanosine, biomarkers of oxidative stress.

Toxicol Lett 2001 Aug;123(1):51-8

Department of Pharmacology and Cancer Biology, Duke University Medical Center, PO Box 3813, Durham, NC 27710, USA.

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August 2001

High-performance liquid chromatographic determination of pyridostigmine bromide, nicotine, and their metabolites in rat plasma and urine.

J Chromatogr Sci 2001 Jul;39(7):287-92

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1093/chromsci/39.7.287DOI Listing
July 2001

Inhibition of cholinesterase enzymes following a single dermal dose of chlorpyrifos and methyl parathion, alone and in combination, in pregnant rats.

J Toxicol Environ Health A 2001 Jun;63(3):173-89

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1080/15287390151101529DOI Listing
June 2001

Quantification of nicotine, chlorpyrifos and their metabolites in rat plasma and urine using high-performance liquid chromatography.

J Chromatogr B Biomed Sci Appl 2001 Jun;757(2):295-300

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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June 2001

Combined exposure to DEET (N,N-diethyl-m-toluamide) and permethrin-induced release of rat brain mitochondrial cytochrome c.

J Toxicol Environ Health A 2001 Jun;63(4):243-52

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1080/15287390151143640DOI Listing
June 2001

High performance liquid chromatographic determination of diazinon, permethrin, DEET (N, N-diethyl-m-toluamide), and their metabolites in rat plasma and urine.

Fresenius J Anal Chem 2001 Jun;370(4):403-7

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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June 2001

Determination of diazinon, chlorpyrifos, and their metabolites in rat plasma and urine by high-performance liquid chromatography.

J Chromatogr Sci 2001 May;39(5):200-4

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1093/chromsci/39.5.200DOI Listing
May 2001

Locomotor and sensorimotor performance deficit in rats following exposure to pyridostigmine bromide, DEET, and permethrin, alone and in combination.

Toxicol Sci 2001 Apr;60(2):305-14

Department of Pharmacology and Cancer Biology, Duke University Medical Center, North Carolina, USA.

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http://dx.doi.org/10.1093/toxsci/60.2.305DOI Listing
April 2001

Effects of daily dermal application of DEET and epermethrin, alone and in combination, on sensorimotor performance, blood-brain barrier, and blood-testis barrier in rats.

J Toxicol Environ Health A 2001 Apr;62(7):523-41

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1080/152873901300007824DOI Listing
April 2001

Induction of urinary excretion of 3-nitrotyrosine, a marker of oxidative stress, following administration of pyridostigmine bromide, DEET (N,N-diethyl-m-toluamide) and permethrin, alone and in combination in rats.

Toxicol Lett 2001 Apr;121(2):127-34

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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April 2001

Chromatographic method for the determination of diazepam, pyridostigmine bromide, and their metabolites in rat plasma and urine.

J Chromatogr B Biomed Sci Appl 2001 Apr;754(2):503-9

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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April 2001

Development of a high-performance liquid chromatographic method for the quantification of chlorpyrifos, pyridostigmine bromide, N,N-diethyl-m-toluamide and their metabolites in rat plasma and urine.

J Chromatogr B Biomed Sci Appl 2001 Apr;754(2):533-8

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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April 2001

Enhanced activity and level of protein kinase A in the spinal cord supernatant of diisopropyl phosphorofluoridate (DFP)-treated hens. Distribution of protein kinases and phosphatases in spinal cord subcellular fractions.

Mol Cell Biochem 2001 Apr;220(1-2):15-23

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27708, USA.

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April 2001

Alteration in cytoskeletal protein levels in sciatic nerve on post-treatment of diisopropyl phosphorofluoridate (DFP)-treated hen with phenylmethylsulfonyl fluoride.

Neurochem Res 2001 Mar;26(3):235-43

Neurotoxicology Laboratory, School of Life Science, University of Science and Technology of China, Hefei, Anhui, PR China.

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March 2001

Altered time course of mRNA expression of alpha tubulin in the central nervous system of hens treated with diisopropyl phosphorofluoridate (DFP).

Neurochem Res 2001 Jan;26(1):43-50

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27708, USA.

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January 2001

Subchronic effects following a single sarin exposure on blood-brain and blood-testes barrier permeability, acetylcholinesterase, and acetylcholine receptors in the central nervous system of rat: a dose-response study.

J Toxicol Environ Health A 2000 Dec;61(8):695-707

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1080/00984100050195161DOI Listing
December 2000

Simultaneous determination of pyridostigmine bromide, N,N-diethyl-m-toluamide, permethrin, and their metabolites in rat plasma and urine by high-performance liquid chromatography.

J Chromatogr B Biomed Sci Appl 2000 Dec;749(2):171-8

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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December 2000

Early differential induction of C-jun in the central nervous system of hens treated with diisopropylphosphorofluoridate (DFP).

Neurochem Res 2000 Dec;25(12):1579-86

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27708, USA.

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December 2000

Increased 8-hydroxy-2'-deoxyguanosine, a biomarker of oxidative DNA damage in rat urine following a single dermal dose of DEET (N, N-diethyl-m-toluamide), and permethrin, alone and in combination.

Toxicol Lett 2000 Nov;117(3):151-60

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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November 2000

Acute sarin exposure causes differential regulation of choline acetyltransferase, acetylcholinesterase, and acetylcholine receptors in the central nervous system of the rat.

Toxicol Sci 2000 Sep;57(1):112-20

Department of Pharmacology and Cancer Biology, Duke University Medical Center, P.O. Box 3813, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1093/toxsci/57.1.112DOI Listing
September 2000

Altered expression of neurofilament subunits in diisopropyl phosphorofluoridate-treated hen spinal cord and their presence in axonal aggregations.

Brain Res 2000 Sep;878(1-2):32-47

Department of Pharmacology and Cancer Biology, Duke University Medical Center, P.O. Box 3813, Durham, NC, USA.

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http://dx.doi.org/10.1016/s0006-8993(00)02642-1DOI Listing
September 2000

Urinary excretion of metabolites following a single dermal dose of [14C]methyl parathion in pregnant rats.

Toxicology 2000 Sep;150(1-3):119-27

Department of Pharmacology and Cancer Biology, Duke University Medical Center, PO Box 3813, 27710, Durham, NC, USA.

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September 2000

Placental transfer and pharmacokinetics of a single oral dose of [14C]p-nitrophenol in rats.

Arch Toxicol 2000 Sep;74(7):388-96

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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September 2000

Heavy metals in Egyptian spices and medicinal plants and the effect of processing on their levels.

J Agric Food Chem 2000 Jun;48(6):2300-4

Food and Dairy Technology Department, National Research Center, Dokki, Cairo, Egypt.

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June 2000

Alterations in levels of mRNAs coding for glial fibrillary acidic protein (GFAP) and vimentin genes in the central nervous system of hens treated with diisopropyl phosphorofluoridate (DFP).

Neurochem Res 2000 Jun;25(6):809-16

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27708, USA.

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June 2000

C-fos mRNA induction in the central and peripheral nervous systems of diisopropyl phosphorofluoridate (DFP)-treated hens.

Neurochem Res 2000 Mar;25(3):327-34

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27708, USA.

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March 2000

Neurotoxicity of ethyl methacrylate in rats.

J Toxicol Environ Health A 2000 Jan;59(2):97-118

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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January 2000

Placental transfer and pharmacokinetics of a single dermal dose of [14C]methyl parathion in rats.

Toxicol Sci 2000 Jan;53(1):5-12

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1093/toxsci/53.1.5DOI Listing
January 2000

Acrylamide-regulated neurofilament expression in rat pheochromocytoma cells.

Brain Res 2000 Jan;852(2):297-304

Department of Pharmacology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/s0006-8993(99)02104-6DOI Listing
January 2000

Enhanced mRNA expression of neurofilament subunits in the brain and spinal cord of diisopropyl phosphorofluoridate-treated hens.

Biochem Pharmacol 1999 Jun;57(11):1245-51

Department of Pharmacology, Duke University Medical Center, Durham, NC 27708, USA.

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http://dx.doi.org/10.1016/s0006-2952(99)00038-6DOI Listing
June 1999

Tau phosphorylation by diisopropyl phosphorofluoridate (DFP)-treated hen brain supernatant inhibits its binding with microtubules: role of Ca2+/Calmodulin-dependent protein kinase II in tau phosphorylation.

Arch Biochem Biophys 1999 May;365(2):268-78

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina, 27708, USA.

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http://dx.doi.org/10.1006/abbi.1999.1165DOI Listing
May 1999

Tau proteins-enhanced Ca2+/calmodulin (CaM)-dependent phosphorylation by the brain supernatant of diisopropyl phosphorofluoridate (DFP)-treated hen: tau mutants indicate phosphorylation of more amino acids in tau by CaM kinase II.

Brain Res 1998 Nov;813(1):32-43

Department of Pharmacology and Cancer-Biology, Duke University Medical Center, P.O. Box 3813, Durham, NC 27708, USA.

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http://dx.doi.org/10.1016/s0006-8993(98)00988-3DOI Listing
November 1998

Cytochrome P450 enzymes in chickens: characteristics and induction by xenobiotics.

Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 1998 Nov;121(1-3):73-83

Department of Pharmacology, Duke University Medical Center, Durham, NC 27708, USA.

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November 1998

The organophosphate pesticide chlorpyrifos affects form deprivation myopia.

Invest Ophthalmol Vis Sci 1998 Jun;39(7):1290-4

Neurotoxicology Division, National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA.

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June 1998

cDNA cloning and sequencing of Ca2+/calmodulin-dependent protein kinase IIalpha subunit and its mRNA expression in diisopropyl phosphorofluoridate (DFP)-treated hen central nervous system.

Mol Cell Biochem 1998 Apr;181(1-2):29-39

Department of Pharmacology, Duke University Medical Center, Durham, NC 27710, USA.

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April 1998

Alteration in neurofilament axonal transport in the sciatic nerve of the diisopropyl phosphorofluoridate (DFP)-treated hen.

Biochem Pharmacol 1997 Jun;53(12):1799-806

Department of Pharmacology, Duke University Medical Center, Durham, NC 27708, USA.

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http://dx.doi.org/10.1016/s0006-2952(97)00002-6DOI Listing
June 1997

Acrylamide and carbon disulfide treatments increase the rate of rat brain tubulin polymerization.

Mol Chem Neuropathol 1997 Apr;30(3):223-37

Duke University Medical Center, Department of Pharmacology, Durham, NC 27708, USA.

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April 1997

Increased neurotoxicity following concurrent exposure to pyridostigmine bromide, DEET, and chlorpyrifos.

Fundam Appl Toxicol 1996 Dec;34(2):201-22

Department of Pharmacology, Duke University Medical Center, Durham, North Carolina, 27710, USA.

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December 1996