Abhai K Tripathi

Abhai K Tripathi

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Abhai K Tripathi

Abhai K Tripathi

Publications by authors named "Abhai K Tripathi"

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Transcriptome analysis based detection of Plasmodium falciparum development in Anopheles stephensi mosquitoes.

Sci Rep 2018 08 1;8(1):11568. Epub 2018 Aug 1.

Laboratory of Emerging Pathogens, Division of Emerging and Transfusion Transmitted Diseases, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA.

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http://dx.doi.org/10.1038/s41598-018-29969-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070505PMC
August 2018

Long-acting injectable atovaquone nanomedicines for malaria prophylaxis.

Nat Commun 2018 01 22;9(1):315. Epub 2018 Jan 22.

Division of Clinical Pharmacology, Departments of Medicine and of Pharmacology and Molecular Sciences, The Johns Hopkins University, 725 North Wolfe Street, Baltimore, MD, 21205, USA.

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http://dx.doi.org/10.1038/s41467-017-02603-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778127PMC
January 2018

A no film slot blot for the detection of developing P. falciparum oocysts in mosquitoes.

PLoS One 2017 21;12(4):e0174229. Epub 2017 Apr 21.

Laboratory of Emerging Pathogens, Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0174229PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400236PMC
September 2017

Molecular Markers of Radiation Induced Attenuation in Intrahepatic Plasmodium falciparum Parasites.

PLoS One 2016 2;11(12):e0166814. Epub 2016 Dec 2.

Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0166814PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135057PMC
June 2017

Plasmodium falciparum CRK4 directs continuous rounds of DNA replication during schizogony.

Nat Microbiol 2017 Feb 17;2:17017. Epub 2017 Feb 17.

Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, 651 Huntington Avenue, FXB, Room 202, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nmicrobiol.2017.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328244PMC
February 2017

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

Authors:
Wesley C Van Voorhis John H Adams Roberto Adelfio Vida Ahyong Myles H Akabas Pietro Alano Aintzane Alday Yesmalie Alemán Resto Aishah Alsibaee Ainhoa Alzualde Katherine T Andrews Simon V Avery Vicky M Avery Lawrence Ayong Mark Baker Stephen Baker Choukri Ben Mamoun Sangeeta Bhatia Quentin Bickle Lotfi Bounaadja Tana Bowling Jürgen Bosch Lauren E Boucher Fabrice F Boyom Jose Brea Marian Brennan Audrey Burton Conor R Caffrey Grazia Camarda Manuela Carrasquilla Dee Carter Maria Belen Cassera Ken Chih-Chien Cheng Worathad Chindaudomsate Anthony Chubb Beatrice L Colon Daisy D Colón-López Yolanda Corbett Gregory J Crowther Noemi Cowan Sarah D'Alessandro Na Le Dang Michael Delves Joseph L DeRisi Alan Y Du Sandra Duffy Shimaa Abd El-Salam El-Sayed Michael T Ferdig José A Fernández Robledo David A Fidock Isabelle Florent Patrick V T Fokou Ani Galstian Francisco Javier Gamo Suzanne Gokool Ben Gold Todd Golub Gregory M Goldgof Rajarshi Guha W Armand Guiguemde Nil Gural R Kiplin Guy Michael A E Hansen Kirsten K Hanson Andrew Hemphill Rob Hooft van Huijsduijnen Takaaki Horii Paul Horrocks Tyler B Hughes Christopher Huston Ikuo Igarashi Katrin Ingram-Sieber Maurice A Itoe Ajit Jadhav Amornrat Naranuntarat Jensen Laran T Jensen Rays H Y Jiang Annette Kaiser Jennifer Keiser Thomas Ketas Sebastien Kicka Sunyoung Kim Kiaran Kirk Vidya P Kumar Dennis E Kyle Maria Jose Lafuente Scott Landfear Nathan Lee Sukjun Lee Adele M Lehane Fengwu Li David Little Liqiong Liu Manuel Llinás Maria I Loza Aristea Lubar Leonardo Lucantoni Isabelle Lucet Louis Maes Dalu Mancama Nuha R Mansour Sandra March Sheena McGowan Iset Medina Vera Stephan Meister Luke Mercer Jordi Mestres Alvine N Mfopa Raj N Misra Seunghyun Moon John P Moore Francielly Morais Rodrigues da Costa Joachim Müller Arantza Muriana Stephen Nakazawa Hewitt Bakela Nare Carl Nathan Nathalie Narraidoo Sujeevi Nawaratna Kayode K Ojo Diana Ortiz Gordana Panic George Papadatos Silvia Parapini Kailash Patra Ngoc Pham Sarah Prats David M Plouffe Sally-Ann Poulsen Anupam Pradhan Celia Quevedo Ronald J Quinn Christopher A Rice Mohamed Abdo Rizk Andrea Ruecker Robert St Onge Rafaela Salgado Ferreira Jasmeet Samra Natalie G Robinett Ulrich Schlecht Marjorie Schmitt Filipe Silva Villela Francesco Silvestrini Robert Sinden Dennis A Smith Thierry Soldati Andreas Spitzmüller Serge Maximilian Stamm David J Sullivan William Sullivan Sundari Suresh Brian M Suzuki Yo Suzuki S Joshua Swamidass Donatella Taramelli Lauve R Y Tchokouaha Anjo Theron David Thomas Kathryn F Tonissen Simon Townson Abhai K Tripathi Valentin Trofimov Kenneth O Udenze Imran Ullah Cindy Vallieres Edgar Vigil Joseph M Vinetz Phat Voong Vinh Hoan Vu Nao-Aki Watanabe Kate Weatherby Pamela M White Andrew F Wilks Elizabeth A Winzeler Edward Wojcik Melanie Wree Wesley Wu Naoaki Yokoyama Paul H A Zollo Nada Abla Benjamin Blasco Jeremy Burrows Benoît Laleu Didier Leroy Thomas Spangenberg Timothy Wells Paul A Willis

PLoS Pathog 2016 07 28;12(7):e1005763. Epub 2016 Jul 28.

Medicines for Malaria Venture, Geneva, Switzerland.

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http://dx.doi.org/10.1371/journal.ppat.1005763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965013PMC
July 2016

Gametocytocidal screen identifies novel chemical classes with Plasmodium falciparum transmission blocking activity.

PLoS One 2014 26;9(8):e105817. Epub 2014 Aug 26.

W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0105817PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144897PMC
December 2015

Antimalarial iron chelator FBS0701 blocks transmission by Plasmodium falciparum gametocyte activation inhibition.

Antimicrob Agents Chemother 2015 Mar 15;59(3):1418-26. Epub 2014 Dec 15.

The W. Harry Feinstone Department of Molecular Microbiology and Immunology, Malaria Research Institute, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA

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http://dx.doi.org/10.1128/AAC.04642-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325789PMC
March 2015

A sensitive enhanced chemiluminescent-ELISA for the detection of Plasmodium falciparum circumsporozoite antigen in midguts of Anopheles stephensi mosquitoes.

J Microbiol Methods 2015 Jan 22;108:19-24. Epub 2014 Oct 22.

Laboratory of Emerging Pathogens, Division of Emerging and Transfusion Transmitted Diseases, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Rockville, MD USA. Electronic address:

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http://dx.doi.org/10.1016/j.mimet.2014.10.006DOI Listing
January 2015

Antimalarial chemotherapy: orally curative artemisinin-derived trioxane dimer esters.

Bioorg Med Chem Lett 2015 Jan 27;25(2):245-8. Epub 2014 Nov 27.

Department of Chemistry, School of Arts and Sciences, The Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218, United States; The Johns Hopkins Malaria Research Institute, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, MD 21205, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2014.11.064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277730PMC
January 2015

Antimalarial chemotherapy: artemisinin-derived dimer carbonates and thiocarbonates.

Bioorg Med Chem Lett 2014 Jun 16;24(11):2440-3. Epub 2014 Apr 16.

Department of Chemistry, School of Arts and Sciences, The Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218, United States; The Johns Hopkins Malaria Research Institute, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, MD 21205, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2014.04.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074917PMC
June 2014

The survival times of malaria-infected mice are prolonged more by several new two-carbon-linked artemisinin-derived dimer carbamates than by the trioxane antimalarial drug artemether.

Bioorg Med Chem Lett 2014 Mar 30;24(5):1285-9. Epub 2014 Jan 30.

Department of Chemistry, School of Arts and Sciences, The Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218, United States; The Johns Hopkins Malaria Research Institute, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, MD 21205, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2014.01.059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943161PMC
March 2014

Model system to define pharmacokinetic requirements for antimalarial drug efficacy.

Sci Transl Med 2013 Oct;5(205):205ra135

Division of Clinical Pharmacology, Department of Medicine, Johns Hopkins University, 725 North Wolfe Street, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1126/scitranslmed.3006684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845824PMC
October 2013

Antimalarial iron chelator, FBS0701, shows asexual and gametocyte Plasmodium falciparum activity and single oral dose cure in a murine malaria model.

PLoS One 2012 21;7(5):e37171. Epub 2012 May 21.

The Malaria Research Institute, W. Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0037171PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357340PMC
December 2012

Malaria-infected mice live until at least day 30 after a new artemisinin-derived thioacetal thiocarbonate combined with mefloquine are administered together in a single, low, oral dose.

J Med Chem 2012 Sep 27;55(17):7892-9. Epub 2012 Aug 27.

Department of Chemistry, School of Arts and Sciences, The Johns Hopkins University, 3400 North Charles Street, Baltimore, Maryland 21218, USA.

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http://dx.doi.org/10.1021/jm3009986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460521PMC
September 2012

Structure and function of Plasmodium falciparum malate dehydrogenase: role of critical amino acids in co-substrate binding pocket.

Biochimie 2009 Nov-Dec;91(11-12):1509-17. Epub 2009 Sep 20.

National Center for Natural Products Research, School of Pharmacy, University of Mississippi, University MS 38677, USA.

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http://dx.doi.org/10.1016/j.biochi.2009.09.005DOI Listing
April 2010

Plasmodium falciparum-infected erythrocytes induce NF-kappaB regulated inflammatory pathways in human cerebral endothelium.

Blood 2009 Nov 27;114(19):4243-52. Epub 2009 Aug 27.

W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2009-06-22
Publisher Site
http://dx.doi.org/10.1182/blood-2009-06-226415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925626PMC
November 2009

Analysis of quaternary structure of a [LDH-like] malate dehydrogenase of Plasmodium falciparum with oligomeric mutants.

Mol Cell Biochem 2009 May 29;325(1-2):141-8. Epub 2009 Jan 29.

National Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS 38677, USA.

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http://dx.doi.org/10.1007/s11010-009-0028-2DOI Listing
May 2009

Plasmodium falciparum-infected erythrocytes decrease the integrity of human blood-brain barrier endothelial cell monolayers.

J Infect Dis 2007 Apr 21;195(7):942-50. Epub 2007 Feb 21.

W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1086/512083DOI Listing
April 2007

The role of neutral lipid nanospheres in Plasmodium falciparum haem crystallization.

Biochem J 2007 Feb;402(1):197-204

Malaria Research Institute, W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1042/BJ20060986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1783988PMC
February 2007

Plasmodium falciparum-infected erythrocytes increase intercellular adhesion molecule 1 expression on brain endothelium through NF-kappaB.

Infect Immun 2006 Jun;74(6):3262-70

W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, 720 Rutland Avenue, Ross 1170, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1128/IAI.01625-05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1479273PMC
June 2006

An alpha-proteobacterial type malate dehydrogenase may complement LDH function in Plasmodium falciparum. Cloning and biochemical characterization of the enzyme.

Eur J Biochem 2004 Sep;271(17):3488-502

National Center for Natural Product Research, Research Institute of Pharmacological Sciences, University of Mississippi, MS 38677, USA.

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http://dx.doi.org/10.1111/j.1432-1033.2004.04281.xDOI Listing
September 2004

Spectrophotometric determination of de novo hemozoin/beta-hematin formation in an in vitro assay.

Anal Biochem 2004 Feb;325(1):85-91

National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, MS 38677, USA.

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http://dx.doi.org/10.1016/j.ab.2003.10.016DOI Listing
February 2004

A physiochemical mechanism of hemozoin (beta-hematin) synthesis by malaria parasite.

Biochem Biophys Res Commun 2002 Jan;290(1):595-601

Division of Biochemistry, Central Drug Research Institute, Lucknow-226001 (UP), India.

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http://dx.doi.org/10.1006/bbrc.2001.6231DOI Listing
January 2002