Publications by authors named "Abdel Kareem Azab"

70Publications

Nanoparticle T-cell engagers as a modular platform for cancer immunotherapy.

Authors:
Kinan Alhallak Jennifer Sun Katherine Wasden Nicole Guenthner Julie O'Neal Barbara Muz Justin King Daniel Kohnen Ravi Vij Samuel Achilefu John F DiPersio Abdel Kareem Azab

Leukemia 2021 Jan 21. Epub 2021 Jan 21.

Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, USA.

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January 2021

Targeting E-selectin to Tackle Cancer Using Uproleselan.

Authors:
Barbara Muz Anas Abdelghafer Matea Markovic Jessica Yavner Anupama Melam Noha Nabil Salama Abdel Kareem Azab

Cancers (Basel) 2021 Jan 18;13(2). Epub 2021 Jan 18.

Department of Radiation Oncology, Cancer Biology Division, Washington University in St. Louis School of Medicine, St. Louis, MO 63108, USA.

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January 2021

Localized Delivery of Cisplatin to Cervical Cancer Improves Its Therapeutic Efficacy and Minimizes Its Side Effect Profile.

Authors:
Cinzia Federico Jennifer Sun Barbara Muz Kinan Alhallak Pippa F Cosper Naoshad Muhammad Amanda Jeske Amanda Hinger Stephanie Markovina Perry Grigsby Julie K Schwarz Abdel Kareem Azab

Int J Radiat Oncol Biol Phys 2020 Nov 27. Epub 2020 Nov 27.

Department of Radiation Oncology, Cancer Biology Division, Washington University in St Louis School of Medicine, St Louis, Missouri; Department of Biomedical Engineering, Washington University in St Louis McKelvey School of Engineering, St Louis, Missouri; Alvin J. Siteman Cancer Center, Washington University School of Medicine, St Louis, Missouri. Electronic address:

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November 2020

Tumor microenvironment-targeted nanoparticles loaded with bortezomib and ROCK inhibitor improve efficacy in multiple myeloma.

Authors:
Cinzia Federico Kinan Alhallak Jennifer Sun Kathleen Duncan Feda Azab Gail P Sudlow Pilar de la Puente Barbara Muz Vaishali Kapoor Luna Zhang Fangzheng Yuan Matea Markovic Joseph Kotsybar Katherine Wasden Nicole Guenthner Shannon Gurley Justin King Daniel Kohnen Noha N Salama Dinesh Thotala Dennis E Hallahan Ravi Vij John F DiPersio Samuel Achilefu Abdel Kareem Azab

Nat Commun 2020 11 27;11(1):6037. Epub 2020 Nov 27.

Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, USA.

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November 2020

Targeting CD47 as a Novel Immunotherapy for Multiple Myeloma.

Authors:
Jennifer Sun Barbara Muz Kinan Alhallak Matea Markovic Shannon Gurley Zhe Wang Nicole Guenthner Katherine Wasden Mark Fiala Justin King Daniel Kohnen Noha Nabil Salama Ravi Vij Abdel Kareem Azab

Cancers (Basel) 2020 Jan 28;12(2). Epub 2020 Jan 28.

Department of Radiation Oncology, Cancer Biology Division, Washington University in St. Louis School of Medicine, St. Louis, MO 63108, USA.

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January 2020

CXCR4-targeted PET imaging using Cu-AMD3100 for detection of Waldenström Macroglobulinemia.

Authors:
Barbara Muz Nilantha Bandara Cedric Mpoy Jennifer Sun Kinan Alhallak Feda Azab Buck E Rogers Abdel Kareem Azab

Cancer Biol Ther 2020 1;21(1):52-60. Epub 2019 Oct 1.

Department of Radiation Oncology, Cancer Biology Division, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.

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October 2019

Inhibition of E-Selectin (GMI-1271) or E-selectin together with CXCR4 (GMI-1359) re-sensitizes multiple myeloma to therapy.

Authors:
Barbara Muz Feda Azab Mark Fiala Justin King Daniel Kohnen William E Fogler Ted Smith John L Magnani Ravi Vij Abdel Kareem Azab

Blood Cancer J 2019 08 20;9(9):68. Epub 2019 Aug 20.

Department of Radiation Oncology, Cancer Biology Division, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.

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August 2019

Thermal Sensitive Liposomes Improve Delivery of Boronated Agents for Boron Neutron Capture Therapy.

Authors:
Micah John Luderer Barbara Muz Kinan Alhallak Jennifer Sun Katherine Wasden Nicole Guenthner Pilar de la Puente Cinzia Federico Abdel Kareem Azab

Pharm Res 2019 Aug 7;36(10):144. Epub 2019 Aug 7.

Department of Radiation Oncology, Cancer Biology Division, Washington University School of Medicine, 4511 Forest Park Ave., Room 3103, St. Louis, MO, 63108, USA.

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August 2019

PYK2/FAK inhibitors reverse hypoxia-induced drug resistance in multiple myeloma.

Authors:
Barbara Muz Maurizio Buggio Feda Azab Pilar de la Puente Mark Fiala Mahesh V Padval David T Weaver Jonathan A Pachter Ravi Vij Abdel Kareem Azab

Haematologica 2019 07 17;104(7):e310-e313. Epub 2019 Jan 17.

Department of Radiation Oncology, Cancer Biology Division, Washington University in Saint Louis School of Medicine, Saint Louis, MO, USA

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July 2019

Inhibition of SDF-1-induced migration of oncogene-driven myeloid leukemia by the L-RNA aptamer (Spiegelmer), NOX-A12, and potentiation of tyrosine kinase inhibition.

Authors:
Ellen L Weisberg Martin Sattler Abdel Kareem Azab Dirk Eulberg Anna Kruschinski Paul W Manley Richard Stone James D Griffin

Oncotarget 2017 Dec 6;8(66):109973-109984. Epub 2017 Nov 6.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.

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December 2017

Enhancing proteasome-inhibitory activity and specificity of bortezomib by CD38 targeted nanoparticles in multiple myeloma.

Authors:
Pilar de la Puente Micah J Luderer Cinzia Federico Abbey Jin Rebecca C Gilson Christopher Egbulefu Kinan Alhallak Shruti Shah Barbara Muz Jennifer Sun Justin King Daniel Kohnen Noha Nabil Salama Samuel Achilefu Ravi Vij Abdel Kareem Azab

J Control Release 2018 01 28;270:158-176. Epub 2017 Nov 28.

Department of Radiation Oncology, Washington University in Saint Louis School of Medicine, MO, USA. Electronic address:

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January 2018

Injectable Hydrogels for Localized Chemotherapy and Radiotherapy in Brain Tumors.

Authors:
Pilar de la Puente Nicole Fettig Micah J Luderer Abbey Jin Shruti Shah Barbara Muz Vaishali Kapoor Sreekrishna M Goddu Noha Nabil Salama Christina Tsien Dinesh Thotala Kooresh Shoghi Buck Rogers Abdel Kareem Azab

J Pharm Sci 2018 03 21;107(3):922-933. Epub 2017 Nov 21.

Department of Radiation Oncology, Washington University in Saint Louis School of Medicine, St. Louis, Missouri 63110; Siteman Cancer Center, Washington University in Saint Louis School of Medicine, St. Louis, Missouri 63110. Electronic address:

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March 2018

Selinexor Overcomes Hypoxia-Induced Drug Resistance in Multiple Myeloma.

Authors:
Barbara Muz Feda Azab Pilar de la Puente Yosef Landesman Abdel Kareem Azab

Transl Oncol 2017 Aug 29;10(4):632-640. Epub 2017 Jun 29.

Department of Radiation Oncology, Cancer Biology Division, Washington University in Saint Louis School of Medicine, Saint Louis, MO 63108, USA. Electronic address:

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August 2017

Tariquidar sensitizes multiple myeloma cells to proteasome inhibitors via reduction of hypoxia-induced P-gp-mediated drug resistance.

Authors:
Barbara Muz Hubert D Kusdono Feda Azab Pilar de la Puente Cinzia Federico Mark Fiala Ravi Vij Noha N Salama Abdel Kareem Azab

Leuk Lymphoma 2017 12 16;58(12):2916-2925. Epub 2017 May 16.

a Department of Radiation Oncology, Cancer Biology Division , Washington University in Saint Louis School of Medicine , St. Louis , MO , USA.

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December 2017

Nanoparticle delivery systems, general approaches, and their implementation in multiple myeloma.

Authors:
Pilar de la Puente Abdel Kareem Azab

Eur J Haematol 2017 Jun 28;98(6):529-541. Epub 2017 Mar 28.

Cancer Biology Division, Department of Radiation Oncology, Washington University in Saint Louis School of Medicine, St. Louis, MO, USA.

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June 2017

The eIF2-alpha kinase HRI is a novel therapeutic target in multiple myeloma.

Authors:
Nicholas Burwick Michael Y Zhang Pilar de la Puente Abdel Kareem Azab Teresa S Hyun Melisa Ruiz-Gutierrez Marilyn Sanchez-Bonilla Tomoka Nakamura Jeffrey J Delrow Vivian L MacKay Akiko Shimamura

Leuk Res 2017 04 12;55:23-32. Epub 2017 Jan 12.

Clinical Research Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, Seattle, WA, USA; Department of Pediatric Hematology/Oncology, Seattle Children's Hospital, 4800 Sand Point Way, Seattle, WA, USA; Department of Pediatrics, University of Washington, 1959 NE Pacific St., Seattle, WA, USA.

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April 2017

Direct measurement of hypoxia in a xenograft multiple myeloma model by optical-resolution photoacoustic microscopy.

Authors:
Toru Imai Barbara Muz Cheng-Hung Yeh Junjie Yao Ruiying Zhang Abdel Kareem Azab Lihong Wang

Cancer Biol Ther 2017 02 3;18(2):101-105. Epub 2017 Jan 3.

a Department of Biomedical Engineering , Washington University in St. Louis , St. Louis , MO , USA.

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February 2017

The role of hypoxia in cancer progression, angiogenesis, metastasis, and resistance to therapy.

Authors:
Barbara Muz Pilar de la Puente Feda Azab Abdel Kareem Azab

Hypoxia (Auckl) 2015 11;3:83-92. Epub 2015 Dec 11.

Department of Radiation Oncology, Cancer Biology Division, Washington University School of Medicine in St Louis, MO, USA.

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December 2015

Drug Delivery Approaches for the Treatment of Cervical Cancer.

Authors:
Farideh Ordikhani Mustafa Erdem Arslan Raymundo Marcelo Ilyas Sahin Perry Grigsby Julie K Schwarz Abdel Kareem Azab

Pharmaceutics 2016 Jul 20;8(3). Epub 2016 Jul 20.

Department of Radiation Oncology, Cancer Biology Division, Washington University School of Medicine, Saint Louis, MO 63108, USA.

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July 2016

A Hypoxia-Targeted Boron Neutron Capture Therapy Agent for the Treatment of Glioma.

Authors:
Micah John Luderer Barbara Muz Pilar de la Puente Sanmathi Chavalmane Vaishali Kapoor Raymundo Marcelo Pratim Biswas Dinesh Thotala Buck Rogers Abdel Kareem Azab

Pharm Res 2016 10 11;33(10):2530-9. Epub 2016 Jul 11.

Department of Radiation Oncology, Cancer Biology Division, Washington University in St. Louis School of Medicine, 4511 Forest Park Ave., Room 3103, St. Louis, Missouri, 63108, USA.

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October 2016