Abbas Mirshafiey, PhD - Tehran University of Medical Sciences - Full professor in Immunology

Abbas Mirshafiey

PhD

Tehran University of Medical Sciences

Full professor in Immunology

Tehran, Tehran | Iran (Islamic Republic of)

Additional Specialties: Drug design / Autoimmunity /Inflammation

ORCID logohttps://orcid.org/0000-0003-1996-2747

Abbas Mirshafiey, PhD - Tehran University of Medical Sciences - Full professor in Immunology

Abbas Mirshafiey

PhD

Introduction

Primary Affiliation: Tehran University of Medical Sciences - Tehran, Tehran , Iran (Islamic Republic of)

Additional Specialties:

Research Interests:

Education

Sep 1987 - Sep 1991
Tehran University of Medical Sciences
PhD/ Full professor
Immunology

Experience

Oct 1991
Tehran University of Medical Sciences
Immunopharmacologist / full professor
Immunology

Publications

100Publications

2175Reads

246Profile Views

224PubMed Central Citations

Modification of Sexual Hormones in Rheumatoid Arthritis Patients by M2000 (β-D-mannuronic Acid) as a Novel NSAID with Immunosuppressive Property.

Endocr Metab Immune Disord Drug Targets 2018 ;18(5):530-536

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.2174/1871530318666180418111354DOI Listing
January 2019
24 Reads

Evaluation of the Effect of α-L-Guluronic Acid (G2013) on COX-1, COX-2 Activity and Gene Expression for Introducing this Drug as a Novel NSAID with Immunomodulatory Property.

Recent Pat Inflamm Allergy Drug Discov 2018 ;12(2):162-168

Department of Chemical, Biological, Pharmacological and Environmental Sciences, University of Messina, Messina, Italy.

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http://dx.doi.org/10.2174/1872213X12666180607121809DOI Listing
December 2018
15 Reads

The imbalance of circulating T helper subsets and regulatory T cells in patients with LRBA deficiency: Correlation with disease severity.

J Cell Physiol 2018 Nov 28;233(11):8767-8777. Epub 2018 May 28.

Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1002/jcp.26772DOI Listing
November 2018
13 Reads
3.840 Impact Factor

Cardioprotective effect of β-d-mannuronic acid (M2000) as a novel NSAID on gene expression of oxLDL scavenger receptors in the experimental diabetic model.

Immunopharmacol Immunotoxicol 2018 Aug 5;40(4):284-289. Epub 2018 Apr 5.

a Department of Immunology, School of Public Health , Tehran University of Medical Sciences , Tehran , Iran.

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http://dx.doi.org/10.1080/08923973.2018.1455209DOI Listing
August 2018
189 Reads
1.110 Impact Factor

Anti-diabetic effect of β-D-mannuronic acid (M2000) as a novel NSAID with immunosuppressive property on insulin production, blood glucose, and inflammatory markers in the experimental diabetes model.

Arch Physiol Biochem 2018 Jun 8:1-6. Epub 2018 Jun 8.

a Department of Immunology , School of Public Health, Tehran University of Medical Sciences , Tehran , Iran.

This research aimed to evaluate the anti-diabetic effects of ?-d-mannuronic acid (M2000) on blood glucose, insulin production, and inflammatory markers in streptozotocin-induced diabetic rats. Our data showed that the final fasting serum glucose level was significantly lower in the M2000-treated group compared to the diabetic control group (p?

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http://dx.doi.org/10.1080/13813455.2018.1481094DOI Listing
June 2018
95 Reads
1 Citation
1.806 Impact Factor

A Review on Defects of Dendritic Cells in Common Variable Immunodeficiency.

Endocr Metab Immune Disord Drug Targets 2017 ;17(2):100-113

Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran. Iran.

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http://dx.doi.org/10.2174/1871530317666170613125009DOI Listing
June 2018
25 Reads
1 Citation

Anti-angiogenesis effect of β-D-mannuronic acid (M2000) as a novel NSAID with immunosuppressive properties under experimental model.

Clin Exp Pharmacol Physiol 2018 Apr 4;45(4):370-376. Epub 2018 Feb 4.

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1111/1440-1681.12907DOI Listing
April 2018
33 Reads

Oral administration effects of β-d-mannuronic acid (M2000) on Th17 and regulatory T cells in patients with ankylosing spondylitis.

Biomed Pharmacother 2018 Apr 23;100:495-500. Epub 2018 Feb 23.

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.biopha.2018.02.059DOI Listing
April 2018
29 Reads
2.023 Impact Factor

The effect of 1, 25(OH)2 D3 (calcitriol) alone and in combination with all-trans retinoic acid on ROR-γt, IL-17, TGF-β, and FOXP3 gene expression in experimental autoimmune encephalomyelitis.

Nutr Neurosci 2018 Apr 20;21(3):210-218. Epub 2016 Dec 20.

a Department of Cellular and Molecular Nutrition , School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences , Tehran , Iran.

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http://dx.doi.org/10.1080/1028415X.2016.1263039DOI Listing
April 2018
26 Reads
1 Citation
2.114 Impact Factor

Vitamin D3 Induces Gene Expression of Ox-LDL Scavenger Receptors in Streptozotocin-Induced Diabetic Rat Aortas: New Insight into the Role of Vitamin D in Diabetic Atherosclerosis.

Rep Biochem Mol Biol 2018 Apr;6(2):170-177

Department of Cellular and Molecular Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS), Tehran, Iran.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941119PMC
April 2018
11 Reads

Therapeutic effects of pegylated-interferon-α2a in a mouse model of multiple sclerosis.

Cent Eur J Immunol 2018 30;43(1):9-17. Epub 2018 Mar 30.

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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https://www.termedia.pl/doi/10.5114/ceji.2018.74868
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http://dx.doi.org/10.5114/ceji.2018.74868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927168PMC
March 2018
15 Reads
0.360 Impact Factor

Anti-inflammatory and anti-tumor effects of α-l-guluronic acid (G2013) on cancer-related inflammation in a murine breast cancer model.

Biomed Pharmacother 2018 02 5;98:793-800. Epub 2018 Jan 5.

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.biopha.2017.12.111DOI Listing
February 2018
10 Reads
2.023 Impact Factor

Effects of guluronic acid (G2013) on SHIP1, SOCS1 induction and related molecules in TLR4 signaling pathway.

Int Immunopharmacol 2018 Feb 5;55:323-329. Epub 2018 Jan 5.

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.intimp.2018.01.003DOI Listing
February 2018
38 Reads
2.472 Impact Factor

The Immunomodulatory Role of G2013 (a-L-Guluronic acid) on the Expression of TLR2 and TLR4 in HT29 cell line.

Curr Drug Discov Technol 2018 Feb 25. Epub 2018 Feb 25.

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran. Iran.

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http://www.eurekaselect.com/160081/article
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http://dx.doi.org/10.2174/1570163815666180226093711DOI Listing
February 2018
35 Reads

Targeting of circulating Th17 cells by β-D-mannuronic acid (M2000) as a novel medication in patients with rheumatoid arthritis.

Inflammopharmacology 2018 Feb 23;26(1):57-65. Epub 2017 Oct 23.

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Box: 14155-6446, Tehran, Iran.

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http://dx.doi.org/10.1007/s10787-017-0410-8DOI Listing
February 2018
26 Reads

Immunomodulatory Effect of G2013 (α-L-Guluronic Acid) on the TLR2 and TLR4 in Human Mononuclear Cells.

Curr Drug Discov Technol 2018 ;15(2):123-131

Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.2174/1570163814666170605111331DOI Listing
January 2018
42 Reads
2 Citations

Dual Effects of Cell Free Supernatants from Lactobacillus acidophilus and Lactobacillus rhamnosus GG in Regulation of MMP-9 by Up-Regulating TIMP-1 and Down-Regulating CD147 in PMADifferentiated THP-1 Cells.

Cell J 2018 Jan 4;19(4):559-568. Epub 2017 Nov 4.

Department of Molecular Medicine, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.22074/cellj.2018.4447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672094PMC
January 2018
15 Reads
1 Citation
0.460 Impact Factor

Combination treatment of docosahexaenoic acid (DHA) and all-trans-retinoic acid (ATRA) inhibit IL-17 and RORγt gene expression in PBMCs of patients with relapsing-remitting multiple sclerosis.

Neurol Res 2018 Jan 18;40(1):11-17. Epub 2017 Nov 18.

b Department of Immunology, School of Public Health , Tehran University of Medical Sciences , Tehran , Iran.

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http://dx.doi.org/10.1080/01616412.2017.1382800DOI Listing
January 2018
11 Reads
1 Citation
1.450 Impact Factor

The potent suppressive effect of β-d-mannuronic acid (M2000) on molecular expression of the TLR/NF-kB Signaling Pathway in ankylosing spondylitis patients.

Int Immunopharmacol 2017 Nov 20;52:191-196. Epub 2017 Sep 20.

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.intimp.2017.08.018DOI Listing
November 2017
19 Reads
2.472 Impact Factor

Hematological Improvement of Patients with Active Rheumatoid Arthritis by β-D-Mannuronic Acid (M2000) as a Novel NSAID with Immunosuppressive Property.

Iran J Allergy Asthma Immunol 2017 Oct;16(5):433-442

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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October 2017
14 Reads
1.013 Impact Factor

Anti-inflammatory Property of β-D-Mannuronic Acid (M2000) on Expression and Activity of Matrix Metalloproteinase-2 and -9 through CD147 Molecule in Phorbol Myristate Acetate-differentiated THP-1 Cells.

Iran J Allergy Asthma Immunol 2017 Oct;16(5):443-451

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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October 2017
17 Reads
1.013 Impact Factor

Immunomodulatory effects of M2000 (β-D-Mannuronic acid) on TNF-α, IL-17 and FOXP3 gene expression in patients with inflammatory bowel disease.

Int Immunopharmacol 2017 Oct 17;51:107-113. Epub 2017 Aug 17.

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, International Campus, TUMS-, IC, Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.intimp.2017.08.011DOI Listing
October 2017
24 Reads
2.472 Impact Factor

Introduction of β-d-mannuronic acid (M2000) as a novel NSAID with immunosuppressive property based on COX-1/COX-2 activity and gene expression.

Pharmacol Rep 2017 Oct 25;69(5):1067-1072. Epub 2017 Apr 25.

Department of Clinical Research, Nagasaki Kawatana Medical Center, Nagasaki, Japan; Department of Neurology, Nagasaki Kawatana Medical Center, Nagasaki, Japan.

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http://dx.doi.org/10.1016/j.pharep.2017.04.015DOI Listing
October 2017
24 Reads
1.930 Impact Factor

The Safety Property of β-D-Mannuronic Acid (M2000) as a Novel Immunosuppressive Agent on Differentiation, Maturation and Function of Human Dendritic Cells.

Curr Drug Discov Technol 2016 ;13(3):164-169

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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August 2017
29 Reads

Therapeutic effects of D-aspartate in a mouse model of multiple sclerosis.

J Food Drug Anal 2017 Jul 27;25(3):699-708. Epub 2017 Mar 27.

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.jfda.2016.10.025DOI Listing
July 2017
14 Reads
1 Citation
0.400 Impact Factor

An in vitro evaluation of anti-aging effect of guluronic acid (G2013) based on enzymatic oxidative stress gene expression using healthy individuals PBMCs.

Biomed Pharmacother 2017 Jun 30;90:262-267. Epub 2017 Mar 30.

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Box: 14155-6446, Tehran, Iran. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S07533322173080
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http://dx.doi.org/10.1016/j.biopha.2017.03.066DOI Listing
June 2017
14 Reads
2.023 Impact Factor

Pharmacological effects of β-d-mannuronic acid (M2000) on miR-146a, IRAK1, TRAF6 and NF-κB gene expression, as target molecules in inflammatory reactions.

Pharmacol Rep 2017 Jun 24;69(3):479-484. Epub 2017 Jan 24.

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.pharep.2017.01.021DOI Listing
June 2017
26 Reads
3 Citations
1.930 Impact Factor

The Immunomodulatory Effect of Exoantigens in the Treatment of Experimental Septic Arthritis.

Open Microbiol J 2017 30;11:72-82. Epub 2017 May 30.

Immunology Department, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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http://benthamopen.com/ABSTRACT/TOMICROJ-11-72
Publisher Site
http://dx.doi.org/10.2174/1874285801711010072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470064PMC
May 2017
11 Reads

Abnormality of regulatory T cells in common variable immunodeficiency.

Cell Immunol 2017 05 29;315:11-17. Epub 2016 Dec 29.

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.cellimm.2016.12.007DOI Listing
May 2017
17 Reads
1 Citation
1.924 Impact Factor

Preclinical and pharmacotoxicology evaluation of α-l-guluronic acid (G2013) as a non-steroidal anti-inflammatory drug with immunomodulatory property.

Immunopharmacol Immunotoxicol 2017 Apr 1;39(2):59-65. Epub 2017 Feb 1.

a Department of Immunology, School of Public Health , Tehran University of Medical Science , Tehran , Iran.

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http://dx.doi.org/10.1080/08923973.2017.1282512DOI Listing
April 2017
29 Reads
1 Citation
1.110 Impact Factor

Targeting of crosstalk between tumor and tumor microenvironment by β-D mannuronic acid (M2000) in murine breast cancer model.

Cancer Med 2017 03 17;6(3):640-650. Epub 2017 Feb 17.

Cancer Research Center and Department of Immunology, Semnan University of Medical Sciences, Semnan, Iran.

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http://dx.doi.org/10.1002/cam4.1013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345625PMC
March 2017
22 Reads
1 Citation

The Effect of PTCC 1643 on Cultured Intestinal Epithelial Cells Infected with serovar Enteritidis.

Osong Public Health Res Perspect 2017 Feb 28;8(1):54-60. Epub 2017 Feb 28.

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.24171/j.phrp.2017.8.1.07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402851PMC
February 2017
8 Reads

Autoimmunity in Primary Antibody Deficiencies.

Int Arch Allergy Immunol 2016 24;171(3-4):180-193. Epub 2016 Dec 24.

Department of Laboratory Medicine, Imam Hassan Mojtaba Hospital, Alborz University of Medical Sciences, Karaj, Iran.

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http://dx.doi.org/10.1159/000453263DOI Listing
February 2017
16 Reads
2.673 Impact Factor

Efficacy and Safety of G2013 as a Novel Immunosuppressive Agent on Differentiation, Maturation and Function of Human Dendritic Cells.

Iran J Public Health 2017 Feb;46(2):216-221

Dept. of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402780PMC
February 2017
22 Reads
0.580 Impact Factor

Effects of M2000 (D-Mannuronic Acid) on Learning, Memory Retrieval, and Associated Determinants in a Rat Model of Alzheimer's Disease.

Am J Alzheimers Dis Other Demen 2017 Feb 19;32(1):12-21. Epub 2016 Dec 19.

5 Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1177/1533317516678086DOI Listing
February 2017
9 Reads
1 Citation
1.430 Impact Factor

The Role of M2000 as an Anti-inflammatory Agent in Toll-Like Receptor 2/microRNA-155 Pathway.

Avicenna J Med Biotechnol 2017 Jan-Mar;9(1):8-12

Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Department of Immunology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5219823PMC
January 2017
15 Reads
1 Citation

The Biology of β-D-mannuronic acid (M2000) on Human Dendritic Cell Based on MicroRNA-155 and MicroRNA-221.

Curr Drug Discov Technol 2017 ;14(1):53-58

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Box: 14155-6446, Tehran, Iran.

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http://dx.doi.org/10.2174/1570163813666161123121952DOI Listing
January 2017
49 Reads

The Anti-Migraine Effects of M2000 (β-D-Mannuronic Acid) on a Patient with Rheumatoid Arthritis: Case Report.

Curr Clin Pharmacol 2017 ;12(2):127-130

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.2174/1574884712666170605101845DOI Listing
January 2017
38 Reads

Cellular and molecular mechanisms of immune dysregulation and autoimmunity.

Cell Immunol 2016 12 27;310:14-26. Epub 2016 Aug 27.

Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.cellimm.2016.08.012DOI Listing
December 2016
39 Reads
5 Citations
1.924 Impact Factor

Monogenic Auto-inflammatory Syndromes: A Review of the Literature.

Iran J Allergy Asthma Immunol 2016 Dec;15(6):430-444

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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December 2016
25 Reads
1 Citation
1.013 Impact Factor

Anti-aging property of G2013 molecule as a novel immunosuppressive agent on enzymatic and non-enzymatic oxidative stress determinants in Rat model.

Curr Drug Discov Technol 2016 ;13(1):25-33

Department of Immunology , School of Public Health, Tehran University of Medical Sciences, Tehran-Iran.

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December 2016
16 Reads
1 Citation

The role of toll-like receptors in B-cell development and immunopathogenesis of common variable immunodeficiency.

Expert Rev Clin Immunol 2016 14;12(2):195-207. Epub 2015 Dec 14.

a Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center , Tehran University of Medical Sciences , Tehran , Iran.

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http://dx.doi.org/10.1586/1744666X.2016.1114885DOI Listing
November 2016
15 Reads
2 Citations
3.342 Impact Factor

Hydroxycitric acid ameliorates inflammation and oxidative stress in mouse models of multiple sclerosis.

Neural Regen Res 2016 Oct;11(10):1610-1616

Department of Laboratory Medicine, Imam Hassan Mojtaba Hospital, Alborz University of Medical Sciences, Karaj, Iran; Research Centre for Immunodeficiencies, Pediatrics Centre of Excellence, Children's Medical Centre, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.4103/1673-5374.193240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116840PMC
October 2016
33 Reads
2 Citations
0.234 Impact Factor

Autoimmunity in primary T-cell immunodeficiencies.

Expert Rev Clin Immunol 2016 Sep 28;12(9):989-1006. Epub 2016 Apr 28.

b Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center , Tehran University of Medical Sciences , Tehran , Iran.

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http://dx.doi.org/10.1080/1744666X.2016.1177458DOI Listing
September 2016
34 Reads
3.342 Impact Factor

The Potential Role of T Helper Cell 22 and IL-22 in Immunopathogenesis of Multiple Sclerosis.

Innov Clin Neurosci 2016 Jul-Aug;13(7-8):30-6. Epub 2016 Aug 1.

Dr. Fard is with Kish International Campus, University of Tehran, Tehran, Iran; Dr. Azizi is with Imam Hassan Mojtaba Hospital, Alborz University of Medical Sciences, Karaj, Iran and Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran; and Dr. Mirshafiey is with the Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022987PMC
September 2016
14 Reads

Preclinical assessment of β-d-mannuronic acid (M2000) as a non-steroidal anti-inflammatory drug.

Immunopharmacol Immunotoxicol 2015 ;37(6):535-40

a Department of Immunology , School of Public Health, Tehran University of Medical Sciences , Tehran , Iran .

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http://dx.doi.org/10.3109/08923973.2015.1113296DOI Listing
September 2016
28 Reads
3 Citations
1.110 Impact Factor

IL-22 Produced by T helper Cell 22 as a New player in the Pathogenesis of Immune Thrombocytopenia.

Endocr Metab Immune Disord Drug Targets 2015 ;15(3):242-50

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran-14155, Box: 6446, Iran.

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June 2016
12 Reads
1 Citation

EBV and vitamin D status in relapsing-remitting multiple sclerosis patients with a unique cytokine signature.

Med Microbiol Immunol 2016 Apr 13;205(2):143-54. Epub 2015 Sep 13.

Virology Department, School of Public Health (SPH), Tehran University of Medical Sciences (TUMS), Tehran, 14155-6446, Iran.

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http://dx.doi.org/10.1007/s00430-015-0437-7DOI Listing
April 2016
21 Reads
1 Citation
3.040 Impact Factor

In Vitro Effects of Propranolol on T Helper Type 1 Cytokine Profile in Human Leukemic T Cells.

Int J Hematol Oncol Stem Cell Res 2016 Apr;10(2):99-105

Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888155PMC
April 2016
19 Reads
1 Citation

Role of Proangiogenic Factors in Immunopathogenesis of Multiple Sclerosis.

Iran J Allergy Asthma Immunol 2016 Feb;15(1):1-12

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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February 2016
4 Reads
1.013 Impact Factor

Quantitative Evaluation of BAFF, HMGB1, TLR 4 AND TLR 7 Expression in Patients with Relapsing Remitting Multiple Sclerosis.

Iran J Allergy Asthma Immunol 2016 Feb;15(1):75-81

Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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February 2016
13 Reads
1 Citation
1.013 Impact Factor

Dysbiosis of fecal microbiota and high frequency of spp., and Actinomycetes in patients with irritable bowel syndrome and gastroenteritis.

Gastroenterol Hepatol Bed Bench 2016 ;9(4):325-330

Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Science, Tehran, Iran.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118858PMC
January 2016
27 Reads
1 Citation

A Live Vector Expressing HPV16 L1 Generates an Adjuvant-Induced Antibody Response In-vivo.

Iran J Cancer Prev 2015 Dec 23;8(6):e3991. Epub 2015 Dec 23.

Department of Hepatitis and AIDS, Pasteur Institute of Iran, Tehran, IR Iran.

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http://dx.doi.org/10.17795/ijcp-3991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736072PMC
December 2015
11 Reads

Effect of Genistein and L-Carnitine and Their Combination on Gene Expression of Hepatocyte HMG-COA Reductase and LDL Receptor in Experimental Nephrotic Syndrome.

Iran J Public Health 2015 Oct;44(10):1339-47

Dept. of Cellular and Molecular Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644578PMC
October 2015
28 Reads
1 Citation
0.580 Impact Factor

New therapeutic approach by G2013 in experimental model of multiple sclerosis.

Acta Neurol Belg 2015 Sep 12;115(3):259-66. Epub 2014 Nov 12.

Department of Cell and Molecular Biology, Kish International Campus, University of Tehran, Kish, Iran.

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http://dx.doi.org/10.1007/s13760-014-0392-xDOI Listing
September 2015
7 Reads
5 Citations
0.600 Impact Factor

The Role of Inflammatory Mediators in the Pathogenesis of Alzheimer's Disease.

Sultan Qaboos Univ Med J 2015 Aug 24;15(3):e305-16. Epub 2015 Aug 24.

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran;

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http://dx.doi.org/10.18295/squmj.2015.15.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554263PMC
August 2015
22 Reads
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T-helper 22 cells as a new player in chronic inflammatory skin disorders.

Int J Dermatol 2015 Aug;54(8):880-8

Imam Hassan Mojtaba Hospital, Alborz University of Medical Sciences, Karaj, Iran.

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http://dx.doi.org/10.1111/ijd.12883DOI Listing
August 2015
24 Reads
2 Citations
1.230 Impact Factor

The Newly Identified T Helper 22 Cells Lodge in Leukemia.

Int J Hematol Oncol Stem Cell Res 2015 Jul;9(3):143-54

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529682PMC
July 2015
19 Reads

Th22 Cells Contribution in Immunopathogenesis of Rheumatic Diseases.

Iran J Allergy Asthma Immunol 2015 Jun;14(3):246-54

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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June 2015
7 Reads
3 Citations
1.013 Impact Factor

Therapeutic effects of dasatinib in mouse model of multiple sclerosis.

Immunopharmacol Immunotoxicol 2015 Jun 15;37(3):287-94. Epub 2015 May 15.

Imam Hassan Mojtaba Hospital, Alborz University of Medical Sciences , Karaj , Iran .

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http://dx.doi.org/10.3109/08923973.2015.1028074DOI Listing
June 2015
9 Reads
5 Citations
1.110 Impact Factor

Effect of probiotics on the expression of Barrett's oesophagus biomarkers.

J Med Microbiol 2015 Apr 9;64(Pt 4):348-54. Epub 2015 Feb 9.

Division of Food Microbiology, Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Food Microbiology Research Center, Tehran University of Medical Sciences, Tehran, Iran

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http://dx.doi.org/10.1099/jmm.0.000039DOI Listing
April 2015
15 Reads
1 Citation
2.250 Impact Factor

Th1 Cytokine Production Induced by Lactobacillus acidophilus in BALB/c Mice Bearing Transplanted Breast Tumor.

Jundishapur J Microbiol 2015 Apr 18;8(4):e17354. Epub 2015 Apr 18.

Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, IR Iran ; Food Microbiology Research Center, Tehran University of Medical Sciences, Tehran, IR Iran.

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http://dx.doi.org/10.5812/jjm.8(4)2015.17354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449865PMC
April 2015
21 Reads
3 Citations
0.780 Impact Factor

Does lipoic acid consumption affect the cytokine profile in multiple sclerosis patients: a double-blind, placebo-controlled, randomized clinical trial.

Neuroimmunomodulation 2014 6;21(6):291-6. Epub 2014 May 6.

Neurosciences Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

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http://dx.doi.org/10.1159/000356145DOI Listing
March 2015
22 Reads
6 Citations
1.882 Impact Factor

HLA antigens and anti-sperm antibody production in Iranian vasectomized men.

J Biomed Res 2015 Jan;29(1):87-90

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.7555/JBR.29.20140113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342441PMC
January 2015
5 Reads
1 Citation

The Potential Role of Chemokines in Alzheimer's Disease Pathogenesis.

Am J Alzheimers Dis Other Demen 2014 Aug 8;29(5):415-25. Epub 2014 Jan 8.

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

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http://dx.doi.org/10.1177/1533317513518651DOI Listing
August 2014
4 Reads
11 Citations
1.430 Impact Factor

Receptor Tyrosine Kinase and Tyrosine Kinase Inhibitors: New Hope for Success in Multiple Sclerosis Therapy.

Innov Clin Neurosci 2014 Jul;11(7-8):23-36

Dr. Mirshafiey is from the Departmant of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran; Dr. Ghalamfarsa is from Cellular & Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran; Dr. Asghari is from Antimicrobial Resistance Research Center, Faculty of Medicine, Iran University of Medical Science, Tehran, Iran; Dr. Azizi is from Imam Hassan Mojtaba Hospital, Alborz University of Medical Sciences, Karaj, Iran.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204472PMC
July 2014
7 Reads
8 Citations

Effects of imatinib mesylate in mouse models of multiple sclerosis and in vitro determinants.

Iran J Allergy Asthma Immunol 2014 Jun;13(3):198-206

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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June 2014
14 Reads
7 Citations
1.013 Impact Factor

Altered pattern of Naïve and memory B cells and B1 cells in patients with chronic granulomatous disease.

Iran J Allergy Asthma Immunol 2014 Jun;13(3):157-65

Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran and Department of Immunology and Allergy, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.

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June 2014
17 Reads
1.013 Impact Factor

Calcium intervention ameliorates experimental model of multiple sclerosis.

Oman Med J 2014 May;29(3):185-9

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran-14155, Box: 6446, Iran.

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http://dx.doi.org/10.5001/omj.2014.46DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052390PMC
May 2014
18 Reads
2 Citations

The potential role of angiogenic factors in rheumatoid arthritis.

Int J Rheum Dis 2014 May 28;17(4):369-83. Epub 2014 Jan 28.

Imam Hassan Mojtaba Hospital, Alborz University of Medical Sciences, Karaj, Iran.

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http://dx.doi.org/10.1111/1756-185X.12280DOI Listing
May 2014
6 Reads
9 Citations
1.771 Impact Factor

The potential role of iNKT cells in experimental allergic encephalitis and multiple sclerosis.

Immunopharmacol Immunotoxicol 2014 Apr 7;36(2):105-13. Epub 2014 Mar 7.

Department of Immunology, School of Public Health, Tehran University of Medical Sciences , Tehran , Iran .

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http://dx.doi.org/10.3109/08923973.2014.897726DOI Listing
April 2014
5 Reads
1 Citation
1.110 Impact Factor

Alteration in frequency and function of CD4⁺CD25⁺FOXP3⁺ regulatory T cells in patients with immune thrombocytopenic purpura.

Iran J Allergy Asthma Immunol 2014 Apr;13(2):85-92

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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April 2014
18 Reads
5 Citations
1.013 Impact Factor

The role of leukotrienes in immunopathogenesis of rheumatoid arthritis.

Mod Rheumatol 2014 Mar;24(2):225-35

Department of Immunology, School of Public Health, Tehran University of Medical Sciences , Tehran , Iran.

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http://dx.doi.org/10.3109/14397595.2013.854056DOI Listing
March 2014
7 Reads
2 Citations
2.210 Impact Factor

The significance of matrix metalloproteinases in the immunopathogenesis and treatment of multiple sclerosis.

Sultan Qaboos Univ Med J 2014 Feb 27;14(1):e13-25. Epub 2014 Jan 27.

Imam Hassan Mojtaba Hospital, Alborz University of Medical Sciences, Karaj, Iran.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916267PMC
February 2014
7 Reads
10 Citations

Properties of immature myeloid progenitors with nitric-oxide-dependent immunosuppressive activity isolated from bone marrow of tumor-free mice.

PLoS One 2013 2;8(7):e64837. Epub 2013 Jul 2.

Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0064837PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699563PMC
January 2014
7 Reads
5 Citations
3.234 Impact Factor

Positive and negative effects of prostaglandins in Alzheimer's disease.

Psychiatry Clin Neurosci 2014 Jan 2;68(1):50-60. Epub 2013 Sep 2.

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1111/pcn.12092DOI Listing
January 2014
4 Reads
2 Citations
1.620 Impact Factor

Regulatory T cells as a therapeutic tool to induce solid-organ transplant tolerance: current clinical experiences.

Exp Clin Transplant 2013 Oct 30;11(5):379-87. Epub 2013 Jul 30.

Department of Nephrology and Urology Research Center, Bagiyatallah University of Medical Sciences, Bagiyatallah Hospital, Tehran, I.R. Iran.

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http://dx.doi.org/10.6002/ect.2013.0004DOI Listing
October 2013
19 Reads
1 Citation
0.800 Impact Factor

Imatinib mesylate: an innovation in treatment of autoimmune diseases.

Recent Pat Inflamm Allergy Drug Discov 2013 Sep;7(3):259-67

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran- 14155, Box: 6446, Iran.

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September 2013
16 Reads
4 Citations

Autoantigens and autoantibodies in multiple sclerosis.

Iran J Allergy Asthma Immunol 2013 Aug 28;12(4):292-303. Epub 2013 Aug 28.

Departmant of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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August 2013
7 Reads
6 Citations
1.013 Impact Factor

Anti-citrullinated protein antibodies and their clinical utility in rheumatoid arthritis.

Int J Rheum Dis 2013 Aug 15;16(4):379-86. Epub 2013 Jul 15.

Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1111/1756-185X.12129DOI Listing
August 2013
16 Reads
5 Citations
1.771 Impact Factor

The neglected role of histamine in Alzheimer's disease.

Am J Alzheimers Dis Other Demen 2013 Jun 15;28(4):327-36. Epub 2013 May 15.

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1177/1533317513488925DOI Listing
June 2013
5 Reads
7 Citations
1.430 Impact Factor

Th17 Cells in Immunopathogenesis and treatment of rheumatoid arthritis.

Int J Rheum Dis 2013 Jun;16(3):243-53

Imam Hassan Mojtaba Hospital, Alborz University of Medical Sciences, Karaj, Iran.

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http://dx.doi.org/10.1111/1756-185X.12132DOI Listing
June 2013
6 Reads
17 Citations
1.771 Impact Factor

Novel therapeutic approach by nicotine in experimental model of multiple sclerosis.

Innov Clin Neurosci 2013 Apr;10(4):20-5

Ms. Naddafi is from Department of Cellular and Molecular Biology, Kish International Campus, University of Tehran, Tehran, Iran; Dr. Haidari is from Department of Neurology, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran; Mr. Azizi is from Imam Hassan Mojtaba Hospital, Alborz University of Medical Sciences, Kara], Iran; Dr. Sedaghat is from Department of Anatomy and Pathology, Faculty of Medicine, Shahed University, Tehran, Iran; and Dr. Mirshafiey is from Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659034PMC
April 2013
14 Reads
3 Citations

Immune reactivity of Brucella melitensis-vaccinated rabbit serum with recombinant Omp31 and DnaK proteins.

Iran J Microbiol 2013 Mar;5(1):19-23

Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran,Iran.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577567PMC
March 2013
12 Reads
4 Citations

The role of leukotrienes in immunopathogenesis of rheumatoid arthritis.

Mod Rheumatol 2013 Mar 26. Epub 2013 Mar 26.

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Box: 6446, 14155, Tehran, Iran.

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http://dx.doi.org/10.1007/s10165-013-0861-8DOI Listing
March 2013
6 Reads
2 Citations
2.210 Impact Factor

Evaluation of CD4+CD25+FOXP3+ regulatory T cells function in patients with common variable immunodeficiency.

Cell Immunol 2013 Feb 29;281(2):129-33. Epub 2013 Mar 29.

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1016/j.cellimm.2013.03.003DOI Listing
February 2013
9 Reads
9 Citations
1.924 Impact Factor

Conversion of calcineurin inhibitors with mammalian target of rapamycin inhibitors after kidney transplant.

Exp Clin Transplant 2013 Feb;11(1):12-6

Tehran University of Medical Sciences, Tehran, IR Iran.

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February 2013
8 Reads
0.800 Impact Factor

Influenza Virus-like Particle Containing Two Different Subtypes of Hemagglutinin Confers Protection in Mice Against Lethal Challenge With A/PR8 (H1N1) and A/HK (H3N2) Viruses.

Iran Red Crescent Med J 2013 Jan 5;15(1):75-82. Epub 2013 Jan 5.

Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, IR Iran.

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http://dx.doi.org/10.5812/ircmj.6252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589784PMC
January 2013
5 Reads
3 Citations
0.504 Impact Factor

Prostaglandins and rheumatoid arthritis.

Arthritis 2012 7;2012:239310. Epub 2012 Nov 7.

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, P.O. Box 6446, Tehran 14155, Iran.

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http://dx.doi.org/10.1155/2012/239310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502782PMC
November 2012
7 Reads
8 Citations

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