Publications by authors named "Aarron T Willingham"

11Publications

siRNA-optimized Modifications for Enhanced In Vivo Activity.

Mol Ther Nucleic Acids 2012 Jan 24;1:e5. Epub 2012 Jan 24.

Sirna Therapeutics, a wholly owned subsidiary of Merck and Co., San Francisco, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/mtna.2011.4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381598PMC
January 2012

Single-stranded microRNA mimics.

RNA 2012 Oct 21;18(10):1796-804. Epub 2012 Aug 21.

Sirna Therapeutics, a wholly owned subsidiary of Merck & Co., San Francisco, California 94158, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1261/rna.031278.111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446704PMC
October 2012

Adenosine modification may be preferred for reducing siRNA immune stimulation.

Nucleic Acid Ther 2012 Jun 20;22(3):205-10. Epub 2012 Apr 20.

Sirna Therapeutics, a wholly owned subsidiary of Merck and Co., San Francisco, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/nat.2011.0334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047996PMC
June 2012

In vivo activity and duration of short interfering RNAs containing a synthetic 5'-phosphate.

Nucleic Acid Ther 2012 Apr 8;22(2):90-5. Epub 2012 Mar 8.

Sirna Therapeutics, San Francisco, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/nat.2011.0333DOI Listing
April 2012

mRNA knockdown by single strand RNA is improved by chemical modifications.

Nucleic Acids Res 2012 May 16;40(9):4125-36. Epub 2012 Jan 16.

Sirna Therapeutics, 1700 Owens Street, Fourth Floor, San Francisco, CA 94158, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkr1301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351186PMC
May 2012

Genome-wide transcription and the implications for genomic organization.

Nat Rev Genet 2007 Jun 8;8(6):413-23. Epub 2007 May 8.

Affymetrix, Inc., 3420 Central Expressway, Santa Clara, California 95051, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrg2083DOI Listing
June 2007

TUF love for "junk" DNA.

Cell 2006 Jun;125(7):1215-20

Affymetrix, Inc., Santa Clara, CA 95051, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2006.06.009DOI Listing
June 2006

RNAi and HTS: exploring cancer by systematic loss-of-function.

Oncogene 2004 Nov;23(51):8392-400

Department of Chemistry, Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, CA 92093, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/sj.onc.1208217DOI Listing
November 2004

A tissue specific cytochrome P450 required for the structure and function of Drosophila sensory organs.

Mech Dev 2004 Oct;121(10):1289-97

Division of Biology, University of California, San Diego, La Jolla, CA 92093-0649, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.mod.2004.04.017DOI Listing
October 2004