Aaron Pollett

Aaron Pollett

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Aaron Pollett

Aaron Pollett

Publications by authors named "Aaron Pollett"

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Familial PDGFRA-mutation syndrome: somatic and gastrointestinal phenotype.

Hum Pathol 2018 06 25;76:52-57. Epub 2018 Feb 25.

Department of Pathology and Molecular Medicine, Queens University and Kingston General Hospital, Kingston, Ontario, K7L3N6, Canada; Division of Medical Genetics in the Department of Pediatrics, Kingston General Hospital, Kingston, Ontario K7L 2V7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2018.02.014DOI Listing
June 2018

High prevalence of adenomatous colorectal polyps in young cancer survivors treated with abdominal radiation therapy: results of a prospective trial.

Gut 2017 10 13;66(10):1797-1801. Epub 2016 Jul 13.

Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1136/gutjnl-2016-311501DOI Listing
October 2017

Prophylactic Total Gastrectomy: a Prospective Cohort Study of Long-Term Impact on Quality of Life.

J Gastrointest Surg 2016 12 17;20(12):1950-1958. Epub 2016 Oct 17.

Department of Surgery, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1007/s11605-016-3287-8DOI Listing
December 2016

Personalized medicine: CCO's vision, accomplishments and future plans.

Healthc Q 2015 ;17 Spec No:41-3

Provincial Head, Pathology and Laboratory Medicine Program at Cancer Care Ontario. He is an Anatomic Pathologist and Co-Director of the Division of Diagnostic Medical Genetics at Mount Sinai Hospital and an Associate Professor in the Department of Laboratory Medicine and Pathobiology at the University of Toronto.

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November 2016

Ileal "carcinoid" tumors-small size belies deadly intent: high rate of nodal metastasis in tumors ≤1 cm in size.

Hum Pathol 2016 10 18;56:123-7. Epub 2016 Jun 18.

Pathology Unit, San Raffaele Scientific Institute, Ospedale San Raffaele - Milano, 20132 Milano, Italia.

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http://dx.doi.org/10.1016/j.humpath.2016.05.023DOI Listing
October 2016

Progression and Management of Duodenal Neoplasia in Familial Adenomatous Polyposis: A Cohort Study.

Ann Surg 2015 Jun;261(6):1138-44

*Department of Surgery, McMaster University, Hamilton, Ontario, Canada †Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada ‡Familial Gastrointestinal Cancer Registry, Mount Sinai Hospital, Toronto, Ontario, Canada §Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada ¶Department of Pathology, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada; and ‖Division of Gastroenterology, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/SLA.0000000000000734DOI Listing
June 2015

Phenotypic and genotypic characterisation of biallelic mismatch repair deficiency (BMMR-D) syndrome.

Eur J Cancer 2015 May 13;51(8):977-83. Epub 2015 Apr 13.

Division of Haematology/Oncology, Department of Paediatrics, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.ejca.2015.02.008DOI Listing
May 2015

Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers.

Nat Genet 2015 Mar 2;47(3):257-62. Epub 2015 Feb 2.

1] Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada. [2] The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada. [3] Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada. [4] Department of Pediatrics, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/ng.3202DOI Listing
March 2015

Performance characteristics of a brief Family History Questionnaire to screen for Lynch syndrome in women with newly diagnosed endometrial cancer.

Gynecol Oncol 2015 Feb 19;136(2):311-6. Epub 2014 Dec 19.

Division of Gynecologic Oncology, Princess Margaret Hospital/University Health Network, 610 University Ave., Toronto, Ontario M5G 2M9, Canada; Department of Obstetrics and Gynecology, University of Toronto, 27 King's College Circle, Toronto, Ontario M5S 2J7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2014.12.023DOI Listing
February 2015

Performance characteristics of screening strategies for Lynch syndrome in unselected women with newly diagnosed endometrial cancer who have undergone universal germline mutation testing.

Cancer 2014 Dec 31;120(24):3932-9. Epub 2014 Jul 31.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Princess Margaret Hospital/University Health Network, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/cncr.28933DOI Listing
December 2014

The microenvironment-specific transformation of adult stem cells models malignant triton tumors.

PLoS One 2013 9;8(12):e82173. Epub 2013 Dec 9.

Stem Cell Research Center, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States of America ; Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America ; Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America ; Department of Molecular Genetics and Biochemistry, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0082173PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857244PMC
October 2014

The histomorphology of Lynch syndrome-associated ovarian carcinomas: toward a subtype-specific screening strategy.

Am J Surg Pathol 2014 Sep;38(9):1173-81

Departments of *Laboratory Medicine and Pathobiology ‡Obstetrics and Gynecology, Faculty of Medicine, University of Toronto §Division of Gynecologic Oncology §§Department of Pathology, University Health Network ∥Department of Laboratory Medicine and Pathology ¶Zane Cohen Centre for Digestive Diseases, Familial Gastrointestinal Cancer Registry ‡‡Division of General Surgery, Mount Sinai Hospital, Toronto, ON ∥∥Department of Medical Genetics, McGill University Health Centre, Montreal, QB #Division of Gynecologic Oncology ¶¶Department of Pathology and Laboratory Medicine, Faculty of Medicine, University of British Columbia and BC Cancer Agency, Vancouver, BC, Canada †Department of Pathology, Bon Secours Hospital, Cork, Ireland **Department of Histopathology, King Edward Memorial Hospital for Women, Perth, Australia ††Department of Cellular Pathology, Barts Health NHS Trust, London, United Kingdom.

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http://pdfs.journals.lww.com/ajsp/2014/09000/The_Histomorpho
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/PAS.0000000000000298DOI Listing
September 2014

Genetic and clinical determinants of constitutional mismatch repair deficiency syndrome: report from the constitutional mismatch repair deficiency consortium.

Eur J Cancer 2014 Mar 15;50(5):987-96. Epub 2014 Jan 15.

Division of Hematology/Oncology, The Hospital for Sick Children, Institute of Medical Sciences, The University of Toronto, Toronto, Ontario, Canada; Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada; Arthur and Sonia Labbatt Brain Tumor Research Center, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2013.12.005DOI Listing
March 2014

ARID1A loss correlates with mismatch repair deficiency and intact p53 expression in high-grade endometrial carcinomas.

Mod Pathol 2014 Feb 26;27(2):255-61. Epub 2013 Jul 26.

1] Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada [2] Department of Pathology, Toronto General Hospital, University Health Network, Toronto, ON,Canada.

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http://dx.doi.org/10.1038/modpathol.2013.144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603563PMC
February 2014

Mucinous tumor of the appendix with limited peritoneal spread: is there a role for expectant observation?

Ann Surg Oncol 2014 Jan 8;21(1):225-31. Epub 2013 Oct 8.

Department of Surgical Oncology, Mount Sinai and Princess Margaret Hospitals, Toronto, ON, Canada,

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http://dx.doi.org/10.1245/s10434-013-3283-0DOI Listing
January 2014

Unifying diagnosis for adenomatous polyps, café-au-lait macules, and a brain mass?

Gastroenterology 2013 Nov 24;145(5):e3-4. Epub 2013 Sep 24.

Zane Cohen Familial Gastrointestinal Cancer Registry and Department of Surgery, Mount Sinai Hospital, University of Toronto, Toronto, Canada; Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1053/j.gastro.2013.06.044DOI Listing
November 2013

The Fatty Liver Index has limited utility for the detection and quantification of hepatic steatosis in obese patients.

Hepatol Int 2013 Jun 29;7(2):592-9. Epub 2012 Sep 29.

Liver Unit, Division of Gastroenterology and Hepatology, University of Calgary, 6D22, Teaching, Research and Wellness Building, 3280 Hospital Drive NW, Calgary, AB, T2N 4Z6, Canada.

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http://dx.doi.org/10.1007/s12072-012-9401-4DOI Listing
June 2013

Digital pathology: Attitudes and practices in the Canadian pathology community.

J Pathol Inform 2013 14;4. Epub 2013 Mar 14.

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.4103/2153-3539.108540DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624704PMC
April 2013

Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer.

Science 2013 Feb 13;339(6119):543-8. Epub 2012 Dec 13.

Campbell Family Institute, Ontario Cancer Institute, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1126/science.1227670DOI Listing
February 2013

Retroperitoneal pelvic cyst: a diagnostic and therapeutic challenge.

J Obstet Gynaecol Can 2013 Feb;35(2):164-167

Department of Pathology, University of Toronto, Toronto ON.

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http://dx.doi.org/10.1016/S1701-2163(15)31022-7DOI Listing
February 2013

Prevalence of loss of expression of DNA mismatch repair proteins in primary epithelial ovarian tumors.

Int J Gynecol Pathol 2012 Nov;31(6):524-31

Department of Pathology and Laboratory Medicine, Vancouver General Hospital, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1097/PGP.0b013e31824fe2aaDOI Listing
November 2012

Juvenile polyposis, hereditary hemorrhagic telangiectasia, and early onset colorectal cancer in patients with SMAD4 mutation.

J Gastroenterol 2012 Jul 14;47(7):795-804. Epub 2012 Feb 14.

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, ON M5T 3L9, Canada.

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http://dx.doi.org/10.1007/s00535-012-0545-8DOI Listing
July 2012

Controlled Attenuation Parameter (CAP): a noninvasive method for the detection of hepatic steatosis based on transient elastography.

Liver Int 2012 Jul 21;32(6):902-10. Epub 2012 Mar 21.

Liver Unit, Division of Gastroenterology and Hepatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1111/j.1478-3231.2012.02781.xDOI Listing
July 2012

Discordance in fibrosis staging between liver biopsy and transient elastography using the FibroScan XL probe.

J Hepatol 2012 Mar 23;56(3):564-70. Epub 2011 Oct 23.

Liver Unit, Division of Gastroenterology and Hepatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1016/j.jhep.2011.10.007DOI Listing
March 2012

Feasibility and diagnostic performance of the FibroScan XL probe for liver stiffness measurement in overweight and obese patients.

Hepatology 2012 Jan 18;55(1):199-208. Epub 2011 Nov 18.

Liver Unit, Division of Gastroenterology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1002/hep.24624DOI Listing
January 2012

A descriptive analysis of gastric cancer specimen processing techniques.

J Surg Oncol 2011 Mar;103(3):248-56

Sunnybrook Research Institute, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/jso.21827DOI Listing
March 2011

A novel and rapid method of determining the effect of unclassified MLH1 genetic variants on differential allelic expression.

J Mol Diagn 2010 Nov 23;12(6):757-64. Epub 2010 Sep 23.

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.2353/jmoldx.2010.090240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963917PMC
November 2010

Plk4 is required for cytokinesis and maintenance of chromosomal stability.

Proc Natl Acad Sci U S A 2010 Apr 26;107(15):6888-93. Epub 2010 Mar 26.

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, ON M5G 1X5, Canada.

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http://dx.doi.org/10.1073/pnas.0910941107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872425PMC
April 2010

Improving the quality of processing gastric cancer specimens: the pathologist's perspective.

J Surg Oncol 2010 Mar;101(3):195-9

Centre for Health Services Sciences, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/jso.21468DOI Listing
March 2010

A novel complex mutation in MSH2 contributes to both Muir-Torre and Lynch Syndrome.

J Hum Genet 2010 Jan 13;55(1):37-41. Epub 2009 Nov 13.

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/jhg.2009.119DOI Listing
January 2010

Quality indicators for gastric cancer surgery: a survey of practicing pathologists in Ontario.

Ann Surg Oncol 2009 Jul 7;16(7):1883-9. Epub 2009 May 7.

Division of General Surgery, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1245/s10434-009-0468-7DOI Listing
July 2009

Germline BRCA1 mutations predispose to pancreatic adenocarcinoma.

Hum Genet 2008 Oct 2;124(3):271-8. Epub 2008 Sep 2.

Gallinger Lab, Samuel Lunenfeld Research Institute, 60 Murray Street, Toronto, ON, M5G1X5, Canada.

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http://dx.doi.org/10.1007/s00439-008-0554-0DOI Listing
October 2008

Café-au-lait macules and pediatric malignancy caused by biallelic mutations in the DNA mismatch repair (MMR) gene PMS2.

Pediatr Blood Cancer 2008 Jun;50(6):1268-70

Division of General Surgery, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1002/pbc.21514DOI Listing
June 2008

Rectal gastrointestinal stromal tumor mimicking a primary prostatic lesion.

Can J Urol 2008 Jun;15(3):4112-4

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.

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June 2008

Prognostic significance of mesenteric tumor nodules in patients with stage III colorectal cancer.

Cancer 2008 Jan;112(1):50-4

University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/cncr.23136DOI Listing
January 2008

A human colon cancer cell capable of initiating tumour growth in immunodeficient mice.

Nature 2007 Jan 19;445(7123):106-10. Epub 2006 Nov 19.

Division of Cell and Molecular Biology, University Health Network, Toronto, Ontario, M5G 1L7, Canada.

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http://www.nature.com/articles/nature05372
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http://dx.doi.org/10.1038/nature05372DOI Listing
January 2007

Plk4 haploinsufficiency causes mitotic infidelity and carcinogenesis.

Nat Genet 2005 Aug 17;37(8):883-8. Epub 2005 Jul 17.

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Ave. R988, Toronto, Ontario M5G 1X5, Canada.

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http://dx.doi.org/10.1038/ng1605DOI Listing
August 2005

Gastrointestinal cancers and neurofibromatosis type 1 features in children with a germline homozygous MLH1 mutation.

Gastroenterology 2004 Feb;126(2):576-85

Familial Gastrointestinal Cancer Registry and Centre for Cancer Genetics and Department of Surgery, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, ON, Canada.

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http://dx.doi.org/10.1053/j.gastro.2003.11.008DOI Listing
February 2004

Assessment of thin-layer breast aspirates for immunocytochemical evaluation of HER2 status.

Acta Cytol 2003 Nov-Dec;47(6):979-84

Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Department of Laboratory Medicine and Pathobiology, University of Toronto.

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http://dx.doi.org/10.1159/000326671DOI Listing
January 2004

Hereditary nonpolyposis colorectal cancer--molecular basis.

Surgery 2003 Jul;134(1):29-33

Department of Surgery, Centre for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1067/msy.2003.176DOI Listing
July 2003