Aaron M Ring

Aaron M Ring

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Aaron M Ring

Aaron M Ring

Publications by authors named "Aaron M Ring"

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29Publications

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GDF15 Is an Inflammation-Induced Central Mediator of Tissue Tolerance.

Cell 2019 Aug 8;178(5):1231-1244.e11. Epub 2019 Aug 8.

Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06520, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.07.033DOI Listing
August 2019

A Forward Chemical Genetic Screen Reveals Gut Microbiota Metabolites That Modulate Host Physiology.

Cell 2019 May 18;177(5):1217-1231.e18. Epub 2019 Apr 18.

Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.03.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536006PMC
May 2019

Anti-SIRPα antibody immunotherapy enhances neutrophil and macrophage antitumor activity.

Proc Natl Acad Sci U S A 2017 12 20;114(49):E10578-E10585. Epub 2017 Nov 20.

Institute for Stem Cell Biology and Regenerative Medicine, and Ludwig Center for Cancer Stem Cell Research, Stanford University School of Medicine, Stanford, CA 94305;

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http://dx.doi.org/10.1073/pnas.1710877114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724266PMC
December 2017

PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity.

Nature 2017 05 17;545(7655):495-499. Epub 2017 May 17.

Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.

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http://dx.doi.org/10.1038/nature22396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931375PMC
May 2017

Decoupling the Functional Pleiotropy of Stem Cell Factor by Tuning c-Kit Signaling.

Cell 2017 03;168(6):1041-1052.e18

Department of Molecular and Cellular Physiology, Stanford University School of Medicine, 279 Campus Drive, Stanford, CA 94305, USA; Department of Structural Biology, Stanford University School of Medicine, 299 Campus Drive, Stanford, CA 94305, USA; Howard Hughes Medical Institute, Stanford University School of Medicine, 279 Campus Drive, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.02.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526607PMC
March 2017

Structure and Dynamics of PD-L1 and an Ultra-High-Affinity PD-1 Receptor Mutant.

Structure 2016 Oct 8;24(10):1719-1728. Epub 2016 Sep 8.

Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09692126163022
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052120PMC
http://dx.doi.org/10.1016/j.str.2016.06.026DOI Listing
October 2016

Hematopoietic stem cell transplantation in immunocompetent hosts without radiation or chemotherapy.

Sci Transl Med 2016 08;8(351):351ra105

Blood and Marrow Transplantation, Stanford University School of Medicine, Stanford, CA 94305, USA. Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA. Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://stm.sciencemag.org/content/scitransmed/8/351/351ra105
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http://eknygos.lsmuni.lt/springer/351/201-217.pdf
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http://dx.doi.org/10.1126/scitranslmed.aae0501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668627PMC
August 2016

Engineering high-affinity PD-1 variants for optimized immunotherapy and immuno-PET imaging.

Proc Natl Acad Sci U S A 2015 Nov 10;112(47):E6506-14. Epub 2015 Nov 10.

Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305; Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University School of Medicine, Stanford, CA 94305; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305; Department of Pathology, Stanford University Medical Center, Stanford, CA 94305;

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http://dx.doi.org/10.1073/pnas.1519623112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664306PMC
November 2015

Antibodies to Interleukin-2 Elicit Selective T Cell Subset Potentiation through Distinct Conformational Mechanisms.

Immunity 2015 May;42(5):815-25

Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2015.04.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439582PMC
May 2015

Activation and allosteric modulation of a muscarinic acetylcholine receptor.

Nature 2013 Dec 20;504(7478):101-6. Epub 2013 Nov 20.

1] Department of Molecular and Cellular Physiology, Stanford University School of Medicine, 279 Campus Drive, Stanford, California 94305, USA [2].

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http://dx.doi.org/10.1038/nature12735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020789PMC
December 2013

Adrenaline-activated structure of β2-adrenoceptor stabilized by an engineered nanobody.

Nature 2013 Oct 22;502(7472):575-579. Epub 2013 Sep 22.

Department of Molecular and Cellular Physiology, Stanford University, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1038/nature12572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822040PMC
October 2013

Improving macrophage responses to therapeutic antibodies by molecular engineering of SIRPα variants.

Oncoimmunology 2013 Sep 29;2(9):e25773. Epub 2013 Jul 29.

Institute for Stem Cell Biology and Regenerative Medicine; Stanford University School of Medicine; Stanford, CA USA ; Ludwig Center for Cancer Stem Cell Research and Medicine; Stanford University School of Medicine; Stanford, CA USA ; Stanford Cancer Institute; Stanford University School of Medicine; Stanford, CA USA.

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http://dx.doi.org/10.4161/onci.25773DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850276PMC
September 2013

Engineered SIRPα variants as immunotherapeutic adjuvants to anticancer antibodies.

Science 2013 Jul 30;341(6141):88-91. Epub 2013 May 30.

Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1126/science.1238856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810306PMC
July 2013

Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15.

Nat Immunol 2012 Dec 28;13(12):1187-95. Epub 2012 Oct 28.

Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, California, USA.

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http://dx.doi.org/10.1038/ni.2449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501574PMC
December 2012

WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters.

J Biol Chem 2011 Aug 6;286(34):30171-80. Epub 2011 Jul 6.

Department of Genetics, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut 06510, USA.

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http://dx.doi.org/10.1074/jbc.M111.222893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191056PMC
August 2011

Angiotensin II signaling increases activity of the renal Na-Cl cotransporter through a WNK4-SPAK-dependent pathway.

Proc Natl Acad Sci U S A 2009 Mar 24;106(11):4384-9. Epub 2009 Feb 24.

Molecular Physiology Unit, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Universidad Nacional Autónoma de México, Tlalpan 14000 Mexico City, Mexico.

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http://dx.doi.org/10.1073/pnas.0813238106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647339PMC
March 2009

Molecular physiology of the WNK kinases.

Annu Rev Physiol 2008 ;70:329-55

Howard Hughes Medical Institute, Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.

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http://dx.doi.org/10.1146/annurev.physiol.70.113006.100651DOI Listing
May 2008

WNK4 regulates activity of the epithelial Na+ channel in vitro and in vivo.

Proc Natl Acad Sci U S A 2007 Mar 26;104(10):4020-4. Epub 2007 Feb 26.

Departments of Genetics, Medicine, and Molecular Biophysics and Biochemistry, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA.

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http://dx.doi.org/10.1073/pnas.0611727104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1805455PMC
March 2007

An SGK1 site in WNK4 regulates Na+ channel and K+ channel activity and has implications for aldosterone signaling and K+ homeostasis.

Proc Natl Acad Sci U S A 2007 Mar 22;104(10):4025-9. Epub 2007 Feb 22.

Departments of Genetics, Medicine, and Molecular Biophysics and Biochemistry, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA.

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http://dx.doi.org/10.1073/pnas.0611728104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1803763PMC
March 2007