Publications by authors named "Aaron DiAntonio"

95Publications

Multiple domain interfaces mediate SARM1 autoinhibition.

Proc Natl Acad Sci U S A 2021 Jan;118(4)

Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110;

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January 2021

SARM1 acts downstream of neuroinflammatory and necroptotic signaling to induce axon degeneration.

J Cell Biol 2020 Aug;219(8)

Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO.

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August 2020

Domain-centric database to uncover structure of minimally characterized viral genomes.

Sci Data 2020 06 25;7(1):202. Epub 2020 Jun 25.

Department of Genetics, Washington University School of Medicine, St Louis, MO, 63110, USA.

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June 2020

Models of Axon Degeneration in Drosophila Larvae.

Methods Mol Biol 2020 ;2143:311-320

Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, USA.

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January 2020

The SARM1 axon degeneration pathway: control of the NAD metabolome regulates axon survival in health and disease.

Curr Opin Neurobiol 2020 08 17;63:59-66. Epub 2020 Apr 17.

Department of Developmental Biology, Washington University School of Medicine in St. Louis, 660 Euclid Avenue, St. Louis, MO 63110, USA; Needleman Center for Neurometabolism and Axonal Therapeutics, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA. Electronic address:

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August 2020

cADPR is a gene dosage-sensitive biomarker of SARM1 activity in healthy, compromised, and degenerating axons.

Exp Neurol 2020 07 19;329:113252. Epub 2020 Feb 19.

Washington University in Saint Louis, Developmental Biology, St. Louis, MO, USA; Needleman Center for Neurometabolism and Axonal Therapeutics, USA. Electronic address:

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July 2020

DLK Activation Synergizes with Mitochondrial Dysfunction to Downregulate Axon Survival Factors and Promote SARM1-Dependent Axon Degeneration.

Mol Neurobiol 2020 Feb 7;57(2):1146-1158. Epub 2019 Nov 7.

Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO, 63110, USA.

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February 2020

SIK3 suppresses neuronal hyperexcitability by regulating the glial capacity to buffer K and water.

J Cell Biol 2019 12 23;218(12):4017-4029. Epub 2019 Oct 23.

Department of Developmental Biology, Washington University in St. Louis School of Medicine, St. Louis, MO

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December 2019

Wnd/DLK Is a Critical Target of FMRP Responsible for Neurodevelopmental and Behavior Defects in the Drosophila Model of Fragile X Syndrome.

Cell Rep 2019 09;28(10):2581-2593.e5

Department of Developmental Biology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA; Needleman Center for Neurometabolism and Axonal Therapeutics, Washington University School of Medicine in St. Louis, St. Louis, MO 63110, USA. Electronic address:

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September 2019

Axon degeneration: mechanistic insights lead to therapeutic opportunities for the prevention and treatment of peripheral neuropathy.

Authors:
Aaron DiAntonio

Pain 2019 05;160 Suppl 1:S17-S22

Department of Developmental Biology, Washington University Medical School Saint Louis, Saint Louis, MO, United States.

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May 2019

DLK regulates a distinctive transcriptional regeneration program after peripheral nerve injury.

Neurobiol Dis 2019 07 5;127:178-192. Epub 2019 Feb 5.

Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address:

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July 2019

The E3 ligase Highwire promotes synaptic transmission by targeting the NAD-synthesizing enzyme dNmnat.

EMBO Rep 2019 03 28;20(3). Epub 2019 Jan 28.

Department of Developmental Biology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA

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March 2019

Gene therapy targeting SARM1 blocks pathological axon degeneration in mice.

J Exp Med 2019 02 14;216(2):294-303. Epub 2019 Jan 14.

Department of Genetics, Washington University School of Medicine in St. Louis, St. Louis, MO

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February 2019

HSP90 is a chaperone for DLK and is required for axon injury signaling.

Proc Natl Acad Sci U S A 2018 10 1;115(42):E9899-E9908. Epub 2018 Oct 1.

Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110;

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October 2018

Palmitoylation enables MAPK-dependent proteostasis of axon survival factors.

Proc Natl Acad Sci U S A 2018 09 27;115(37):E8746-E8754. Epub 2018 Aug 27.

Department of Developmental Biology, Washington University in St. Louis School of Medicine, St. Louis, MO 63110;

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September 2018

TRPV1 Agonist, Capsaicin, Induces Axon Outgrowth after Injury via Ca/PKA Signaling.

eNeuro 2018 May-Jun;5(3). Epub 2018 May 30.

Department of Developmental Biology, Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA.

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January 2019