Dr Aamir Jalal Mosawi, MD, PhD - Baghdad Medical City - Advisor doctor

Dr Aamir Jalal Mosawi

MD, PhD

Baghdad Medical City

Advisor doctor

Baghdad | Iraq

Main Specialties: Pediatrics

Additional Specialties: Pediatrics

ORCID logohttps://orcid.org/0000-0002-2253-8157

Dr Aamir Jalal Mosawi, MD, PhD - Baghdad Medical City - Advisor doctor

Dr Aamir Jalal Mosawi

MD, PhD

Introduction

Primary Affiliation: Baghdad Medical City - Baghdad , Iraq

Specialties:

Additional Specialties:


View Dr Aamir Jalal Mosawi’s Resume / CV

Experience

Nov 2015
Baghdad Medical City
Senior advisor doctor and expert trainer
Pediatrics/Training and development

Publications

38Publications

118Reads

840Profile Views

15PubMed Central Citations

THE USE OF CEREBROLYSIN AND CITICOLINE IN AUTISM AND ASPERGER SYNDROME

Authors:
Aamir Al Mosawi

J.Bio.Innov 8(1), pp: 99-108, 2019

Journal of Bio Innovation

There is no known curative therapy for pervasive developmental disorders (PDD) which

include autism,  Asperger syndrome, and atypical autism. Marked improvement or

disappearance of autistic features in these disorders has not been reported with any

therapy before.The aim of this paper is report a retrospective observational study

describing the use of a new therapeutic approach for the treatment of eight of 19 patients

with PDD. The treated patients ages ranged from 3 to 16 years. The new therapeutic

approach which included injectable cerebrolysin as the main therapeutic component. The

patients ages ranged from 3 to 8 years. Seven patients had a diagnosis of autism and one

patient had a diagnosis of Asperger syndrome. Treatment aimed at improving the cardinal

feature of PDD which is the impairment of social interaction which is mostly manifested

by poor responsiveness to their name and infrequent engagement with others manifested

by poor eye contact and infrequently looking to faces. All the treated showed

improvement and marked lessening of the autistic features with six patients showed

complete disappearance of the main autistic features. No patient developed any side

effects. The eleven patients observed during the same year who didn’t receive this

treatment or were treated with other treatments such as omega-3 and risperidone didn’t

show any lessening effect in the autistic features. However, one patient was treated with

citicoline injection showed obvious improvement in the autistic features.                                                                                                                               

Key words: Autism, Asperger syndrome, cerebrolysin, citicoline


View Article
January 2019
28 Reads

The use of cerebrolysin and citicoline in autism and Asperger syndrome

J.Bio.Innov

Journal of Bio-innovation

Abstract

There is no known curative therapy for pervasive developmental disorders (PDD) which

include autism,  Asperger syndrome, and atypical autism. Marked improvement or

disappearance of autistic features in these disorders has not been reported with any

therapy before.The aim of this paper is report a retrospective observational study

describing the use of a new therapeutic approach for the treatment of eight of 19 patients

with PDD. The treated patients ages ranged from 3 to 16 years. The new therapeutic

approach which included injectable cerebrolysin as the main therapeutic component. The

patients ages ranged from 3 to 8 years. Seven patients had a diagnosis of autism and one

patient had a diagnosis of Asperger syndrome. Treatment aimed at improving the cardinal

feature of PDD which is the impairment of social interaction which is mostly manifested

by poor responsiveness to their name and infrequent engagement with others manifested

by poor eye contact and infrequently looking to faces. All the treated showed

improvement and marked lessening of the autistic features with six patients showed

complete disappearance of the main autistic features. No patient developed any side

effects. The eleven patients observed during the same year who didn’t receive this

treatment or were treated with other treatments such as omega-3 and risperidone didn’t

show any lessening effect in the autistic features. However, one patient was treated with

citicoline injection showed obvious improvement in the autistic features.                                                                                                                               

Key words: Autism, Asperger syndrome, cerebrolysin, citicoline


View Article
January 2019

The novel occurrence of corneal opacity in association with first case of Aicardi syndrome in an Arab patient

Authors:
Aamir Al Mosawi

Minerva Oftalmologica 2010;62:1-2

Minerva Oftalmologica

The aim of this paper is to report. The novel occurrence of corneal opacity in association with first case of Aicardi syndrome in the Arab.

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December 2010
8 Reads

A New Model for the Management of End-Stage Renal Disease

Pediatr Nephrol, Volume 2010; 25(9): 1862–1862

Pediatric Nephrology

The use of dietary therapies to lower urea levels simulating dialysis procedures was sometimes called intestinal dialysis. In the commonest form of this process, the patient consumes relatively a large amount of soluble fiber. The most commonly used soluble fiber acacia gum is digested by colonic flora, thereby increasing the amount of nitrogen that is eliminated as fecal waste. When acacia fibers gum are added to a low protein diet in patients with advanced chronic kidney disease (CKD) who do not have access to dialysis, their serum BUN levels can be lowered and they experienced a decrease in uremic symptoms. Admittedly, this would appear to be a viable option in situations of limited resources . Other less commonly used types of intestinal dialysis may include the use of other non-absorbable substances such as polyethylene glycol or mannitol . In a series of 80 patients with CRF, In 14 (16.5%) patients were treated with a new therapeutic approach was used. This new approach consists of using acacia gum which is a new therapeutic dietary supplement plus the traditional conservative measures. The use of this novel resulted in amelioration of the uremic symptoms and lowering of blood urea levels and delaying the need for dialysis. In this sample of 80 patients the longest survival of 5 years was achieved in 2 patients, both treated initially with IPD .One of them was transplanted and the other was treated with combination of the traditional conservative measures and acacia gum supplementation.

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September 2010
8 Reads

Cancer in Iraq: 2000-2004.

Eur J Oncol 2010; 15(3-4):145-148.

European Journal of Oncology

Background. Little is known about the frequency of various childhood cancers in Iraq. The aim of this paper is to report the frequency of childhood cancers in Iraq in the largest series of Iraqi patients with cancer. Patients and methods. In the largest series of 63923 Iraqi patients with different types of newly diagnosed cancer registered by the Iraqi Ministry of Health from all Iraqi provinces with exception of 3 Northern provinces (Sulaimanyia, Erbil, and Dohouk) during five-year period (2000-2004), 5049 cases of cancers occurred in children under 14 years of age accounting for approximately 8% of all cancer cases in Iraq. Results. Leukemia is by far the commonest childhood cancer in Iraq accounting for 33% of childhood cancers. The other most frequent childhood cancers were: Hodgkin lymphomas (HL), central nervous system neoplasms, Non-Hodgkin lymphomas (NHL), renal tumors, bone tumors, retinoblastomas, soft tissues tumors, adrenal gland tumors, and tumors of testis and ovary. Conclusion. The pattern of childhood cancer in Iraq is slightly different from the patterns in other countries. A higher frequency of leukemias than in most other countries is observed.

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August 2010
8 Reads

A dysmorphic girl with acrocephaly, seizures, long spindle fingers and cherry red spots: A new association?

Authors:
Aamir Al Mosawi

Minerva Oftalmologica 2010 June; 52(2):63-4.

Minerva Oftalmologica

Objective: To report the association of acrocephaly, cherry red spots, squint, seizures and long spindle fingers which has not been reported before. Case report: A 10 month old girl with generalized tonic clonic convulsion despite treatment with sodium valproate and two of her siblings, a girl and boy were similar in appearance to this girl died from recurrent seizures that didn’t respond to sodium valproate during the first year of life. Seizure was completely controlled with carbamazepine. The aim of this paper is to report a new clinical association. The girl was born at by term with average weight by normal vaginal delivery. The mother did not report taking any drugs during pregnancy. The girl was acrocephaly with flat occiput and has epicanthic fold and bilateral mild convergent squint. At the age of 10 month she didn’t have any visible tooth. Her fingers were long and spindle in shape. All of her growth parameters were just below the third centiles. Fundoscopic examination showed bilateral macular cherry red spots.Cetavlon test for mucopolysachridosis was negative. Serum and urine chromatography showed no abnormal amino acids. CONCLUSION: A new clinical association is reported.

View Article
June 2010
8 Reads

.Cancer in Iraq: 2000-2004

Eur. J. Oncol., vol. 15, n. 3-4, pp. 000-000, 2010

European Journal of Oncology

Background. Little is known about the frequency of various childhood cancers in Iraq. The aim of this paper is to report the frequency of childhood cancers in Iraq in the largest series of Iraqi patients with cancer. Patients and methods. In the largest series of 63923 Iraqi patients with different types of newly diagnosed cancer registered by the Iraqi Ministry of Health from all Iraqi provinces with exception of 3 Northern provinces (Sulaimanyia, Erbil, and Dohouk) during five-year period (2000-2004), 5049 cases of cancers occurred in children under 14 years of age accounting for approximately 8% of all cancer cases in Iraq. Results. Leukemia is by far the commonest childhood cancer in Iraq accounting for 33% of childhood cancers. The other most frequent childhood cancers were:Hodgkin lymphomas (HL), central nervous system neoplasms, Non-Hodgkin lymphomas (NHL), renal tumors, bone tumors, retinoblastomas, soft tissues tumors, adrenal gland tumors, and tumors of testis and ovary. Conclusion. The pattern of childhood cancer in Iraq is slightly

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June 2010
8 Reads

Essential oil terpenes: adjunctive role in the management of childhood urolithiasis.

J Med Food 2010 Apr;13(2):247-50

Department of Pediatrics and CME Center, University Hospital in Al Kadhimiyia, Baghdad, Iraq.

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http://dx.doi.org/10.1089/jmf.2008.0115DOI Listing
April 2010
10 Reads
1 Citation
1.700 Impact Factor

The first case of Niikawa-Kuroki syndrome in Kazakhstan associated with café au lait spots.

G Ital Dermatol Venereol 2009 Oct;144(5):613-5

Department of Pediatrics, University Hospital, Al kadhimiyia, Baghdad, Iraq.

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October 2009
8 Reads
0.491 Impact Factor

Six-year dialysis freedom in end-stage renal disease.

Clin Exp Nephrol 2009 Oct 30;13(5):494-500. Epub 2009 May 30.

Department of Pediatrics, University Hospital in Al Kadhimiyia, PO Box 70025, Baghdad, Iraq.

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http://dx.doi.org/10.1007/s10157-009-0181-7DOI Listing
October 2009
11 Reads
2 Citations
1.710 Impact Factor

The thirty-fifth case of cutis laxa type II (Debre type).

Int J Dermatol 2009 Jul;48(7):755-7

Department of Pediatrics, Al Kadhimiyia University Hospital, Baghdad, Iraq.

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http://dx.doi.org/10.1111/j.1365-4632.2009.03933.xDOI Listing
July 2009
10 Reads
1.230 Impact Factor

CHRONIC RENAL FAILURE IN IRAQI CHILDREN: 14 YEAR EXPERIENCE OF A SINGLE CENTER

Authors:
Aamir Al Mosawi

JNRT 2008; 1(1): 32 – 40.

Journal of Nephrology and Renal Transplantation

Background: Little is known about the pattern of CRF in Iraq because of the lack of central reporting agency. The aim of this paper is to report our extra-ordinary experience with childhood CRF in Iraqi children. Patients& methods: From January 1993 to July 2007, 80 patients with a diagnosis of chronic renal failure (CRF) were observed at the University Hospital in Al Kadhimiyia. Fifty one patients were males (63.75%) and 29 (36.25%) were females. The male-female ratio was 1.75, and the age at referral ranged from 2 months to 18 years (mean 9 years). Results: The single most common cause of CRF was chronic glomerulonephritis (19 %).The largest etiological group was hereditary disorders and genetic syndrome (28.8%). Cystinosis was the most common hereditary disorder causing CRF. Oculo-cerebro-renal syndrome and severe variant of Hinman syndrome which are rare causes of CRF accounted for 10% of the patients. Most patients (93.6%) were treated by conservative measures with or without intermittent peritoneal dialysis (IPD).Five patients were treated with chronic hemodialysis.Only 2 patients received live related donor kidney transplant. In 14 (16.5%) patients of acacia gum supplementation was added to the conservative measures and resulted in amelioration of the uremic symptoms and lowering of blood urea levels and delaying the need for dialysis. The longest survival of 6 years was achieved in 2 patients, both treated initially with IPD.One of the was transplanted and the other was treated with a combination of the traditional conservative measures and acacia gum supplementation. Conclusion: The pattern of childhood CRF in Iraq is unique and differs from previous reports.

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December 2008
8 Reads

Medical education and the physician workforce of Iraq.

J Contin Educ Health Prof 2008 ;28(2):103-5

Department of Pediatrics, University Hospital in Al Kadhimiyia, Baghdad, Iraq.

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http://dx.doi.org/10.1002/chp.166DOI Listing
September 2008
9 Reads
7 Citations
1.361 Impact Factor

SPECTRUM OF RENAL TUBULAR DISORDERS IN IRAQI CHILDREN

Authors:
Aamir Al Mosawi

Pediatric Oncall Journal 2008 Vol 5((9)

Pediatric Oncall Journal

Objectives of study: The pattern of renal tubular disorder (RTDs) has been infrequently reported in the literature. In Germany, the three most frequent disorders were cystinosis, X-linked hypophosphatemic rickets (XLHR), and idiopathic hypercalciuria. This study was undertaken to determine the pattern of RTDs in Iraqi and Arab children. Methods: From June 2000 to April 2007, 42 children with suspected RTD were evaluated to determine the type of tubulopathies. Results: Ages at referral ranged from 8 months to 14 years (mean 4.8 years). There was evidence of RTD in only 37 patients; 23 males (62 %) and 14 females (38 %). Their ages at referral ranged between 8 months and 14 years (Mean 4.8 years). In 4 patients with oculo-cerebro-renal syndrome, there was no evidence of RTD and one patient has hyperoxaluria which was not a RTD. Seven types of RTDs were identified. The three most common disorders were: idiopathic hypercalciuria (35 %), cystinosis (21.6 %) and renal tubular acidosis RTA (21.6%) Four of the patients with RTA have proximal RTA, and four have distal RTA.Four of the patients with hypercalciuria have also significant hyperoxaluria > 3mg/kg/day.

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September 2008
8 Reads

The use of acacia gum in end stage renal failure.

J Trop Pediatr 2007 Oct 21;53(5):362-5. Epub 2007 May 21.

Head of the Department of Pediatrics, University Hospital in Al kadhimiyia, Po Box 70025 Baghdad, Iraq.

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https://academic.oup.com/tropej/article-lookup/doi/10.1093/t
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http://dx.doi.org/10.1093/tropej/fmm033DOI Listing
October 2007
13 Reads
2 Citations
0.860 Impact Factor

Oculo-cerebro-renal syndrome phenotype in four Iraqi children.

Authors:
Aamir Al Mosawi

Journal of Pediatric Neurology .2007; 5 (1):75-78.

Journal of Pediatric Neurology

The oculocerebrorenal syndrome (OCRS) is a rare hereditary disorder characterized by ocular and cerebral defects, hypotonia, hyporeflexia and renal dysfunction. The aim of this study is to report the phenotype OCRS in four Iraqi children. From 1994 to 2005, four patients (two boys and two girls) with OCRS phenotype were observed at Al-Kadhimiyia University Hospital. All described cases had congenital cataract(s), hypotonia and hyporeflexia and renal dysfunction. It was possible to study and follow three of them for several months, while the fourth case was observed only twice and then lost to follow up. Ocular manifestations in the three cases were in the form of cataract and glaucoma; one boy had immature cataracts not affecting the vision, and bilateral congenital chorioretinal hypoplasia. Two boys had nystagmus during infancy, which was undetectable at time of referral of one case. All the patients had hypotonia and hyporeflexia, which developed after 3 years in one girl. Three patients had global developmental delay; however, intelligence and language was well developed in one girl. All the children had end stage renal failure with evidence of glomerular defect. None had any renal tubular dysfunction or Fanconi syndrome. Uremia was the cause of death in the three cases followed up during their first decade. Congenital chorioretinal hypoplasia, which had never been described in OCRS, was present in one among our cases.

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September 2007
301 Reads

Identification of nonneurogenic neurogenic bladder in infants.

Urology 2007 Aug;70(2):355-6; discussion 356-7

Department of Pediatrics, Al Kadhimiyia University Hospital, Al Kadimiyia, Baghdad, Iraq.

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http://dx.doi.org/10.1016/j.urology.2007.04.049DOI Listing
August 2007
10 Reads
1 Citation
2.190 Impact Factor

Continuing Medical education: Principles, concepts, and standards.

The New Iraqi Jof Med 2007 3(2):32-35

The New Iraqi Journal of Medicine

Medicine is witnessing a continuous and tremendous progress in all fields. The enormous strides in the understanding of the bases of diseases have permitted more rational bases for the diagnosis and management of various disorders. New diagnostic tools and new therapies are continuously emerging and contributing to improved patient care and management, and raising the hope for more specific and curtain therapy for many disorders. The medical practice is rapidly changing and the aim of this paper is to briefly review the Principles, concepts, and the generally accepted standards of continuing medical education and its impact on patient care.

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August 2007
8 Reads

Rational for the possible introduction of Haemophilus influenzae vaccine into the Iraq vaccination program

The N Iraqi J Med, Volume 2007; 3(1): 25–28

The New Iraqi Journal of Medicine

Bacterial meningitis remains one of the most potentially serious infections in infants and children with high risk of acute complications and chronic morbidity. Haemophilus influenzae was the most common bacterial pathogens causing meningitis during the first year of life before the introduction of vaccines against Haemophilus influenzae type b(Hib).The wide spread use of Hib vaccines was associated with marked reduction in the frequency of Haemophilus infection, and Haemophilus influenzae is no longer the most common bacterial pathogens causing meningitis during the first year of life in many geographic areas such as UK and USA. In Iraq the precise and even the rough contribution of Haemophilus influenzae and other bacterial pathogens to acute bacterial meningitis and acute CNS infection in general remains unknown. The aim of this paper is to discuss the rational for the possible introduction of Hib vaccine into the Iraq vaccination program based on the success associated with the introduction of the Hib vaccines into the developed counties vaccination program.

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March 2007
8 Reads

Idiopathic hyperuricosuria, hypercalciuria and infantile renal stone disease: new association and therapeutic approach.

Authors:
Aamir Al Mosawi

Therapy 2006:3(6): 755-757

Therapy

Background & aim: Achondroplasia is one of the most commonly known types of skeletal dysplasia, leading to short stature and severe rhizomelic dwarfism with extreme, disproportionate, short stature. Hormonal therapy with a growth hormone was associated with a significant effect on height gain in patients with achondroplasia. Currently, growth hormone is available on a limited basis for patients with growth hormone deficiency. The aim of this paper is to report the effects of a limited number of doses of nandrolone decanoate in a child with achondroplasia and very slow growth in the short term. Materials & methods: A 4-year old girl with achondroplasia was referred owing to her parents concern and anxiety regarding her very slow growth. Growth hormone therapy was not available for the child. On referral, her weight was 13 kg and her height was 76.7 cm. Her height was 76.6 cm 6 months before, and baseline growth velocity during the previous 6 months was considered zero. She received nandolone 25 mg by intramuscular injection at days 1, 10 and 40. Results:The novel use of nandrolone in this child with achondroplasia resulted in a dramatic acceleration in growth without the occurrence of unwanted effects or advancement of bone age. At 2 months after the first nandrolone injection, her height was 80.5 cm. Growth velocity during the 2 months of nandrolone use increased from 0 to 1.9 cm/month. Body proportion (sitting height/total height) did not show any significant change. In this geographical location, and due to highly unusual social factors, we are unable to carry out long-term follow-up. Conclusion: The use of nandrolone was associated with a beneficial effect on growth without any obvious adverse effects. However, these results must be confirmed in additional trials in the future.

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December 2006
8 Reads

Dramatic effect of non-17 alpha alkyl testosterone derivative anabolic agent on growth in a child with achondroplasia on the short term.

Authors:
Aamir Al Mosawi

Therapy 2006:3(5): 605-607.

Therapy

Background & aim: Achondroplasia is one of the most commonly known types of skeletal dysplasia, leading to short stature and severe rhizomelic dwarfism with extreme, disproportionate, short stature. Hormonal therapy with a growth hormone was associated with a significant effect on height gain in patients with achondroplasia. Currently, growth hormone is available on a limited basis for patients with growth hormone deficiency. The aim of this paper is to report the effects of a limited number of doses of nandrolone decanoate in a child with achondroplasia and very slow growth in the short term. Materials & methods: A 4-year old girl with achondroplasia was referred owing to her parents concern and anxiety regarding her very slow growth. Growth hormone therapy was not available for the child. On referral, her weight was 13 kg and her height was 76.7 cm. Her height was 76.6 cm 6 months before, and baseline growth velocity during the previous 6 months was considered zero. She received nandolone 25 mg by intramuscular injection at days 1, 10 and 40. Results: The novel use of nandrolone in this child with achondroplasia resulted in a dramatic acceleration in growth without the occurrence of unwanted effects or advancement of bone age. At 2 months after the first nandrolone injection, her height was 80.5 cm. Growth velocity during the 2 months of nandrolone use increased from 0 to 1.9 cm/month. Body proportion (sitting height/total height) did not show any significant change. In this geographical location, and due to highly unusual social factors, we are unable to carry out long-term follow-up. Conclusion: The use of nandrolone was associated with a beneficial effect on growth without any obvious adverse effects. However, these results must be confirmed in additional trials in the future.

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September 2006
9 Reads

Genetic drift. Letter from Baghdad: Coffin-Siris syndrome in a girl with absent kidney.

Am J Med Genet A 2006 Aug;140(16):1789-90

Department of Pediatrics, Al Kadhymiyia University Hospital, Al Kadimiyia, Baghdad, Iraq.

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http://dx.doi.org/10.1002/ajmg.a.31337DOI Listing
August 2006
7 Reads
2.160 Impact Factor

Nephropathic cystinosis in Iraqi children

The N Iraqi J Med, Volume 2006; 2(2): 22–25

The New Iraqi Journal of Medicine

Background: Nephropathy cystinosis is a rare, autosomal recessive lysosomal storage disorder caused by mutations in the CTNS gene that codes for a cystine transporter in the lysosomal membrane. Affected patients store 50-100 times the normal amounts of cystine in their cells, and suffer renal tubular and glomerular disease, growth retardation, photophobia, and other systemic complications, including a myopathy and swallowing dysfunction. The aim of this study is to describe the pattern of cystinosis in Iraqi children. Patients and Methods: From 1999 to 2005 eight patients with Cystinosis were observed at the university hospital in Al Kadhimiyia.There age ranged from 10 months to 14 years at the time of first referral. (Mean 5 years).The diagnosis of Cystinosis was confirmed by finding the pathognomic corneal cystine crystals on slit lamp examination. Results: Three patients have evidence of Fanconi syndrome and one patient has evidence of RTA on referral. The remaining 4 patients had chronic renal failure on referral with 2 of them have reached end- stage renal failure and have undergone dialysis. Four of the patients with Cystinosis have at least one sibling died from the same illness. The remaining three patients had no family history of similar illness. All the patients have significant growth retardation with all of their growth parameters below the third centile. Among the patients with Cystinosis only one patient was receiving cysteamine sent to him from a relative living in UK. During the follow-up period, two of the patients with Cystinosis died from uremia. Only two of the 7 observed patients had the correct diagnosis of Cystinosis before referral .The remaining 5 patients were diagnosed as having RTA before referral indicating delay in referring the patients to the appropriate consultant. Conclusion: The outcome of nephropathic cystiosis in Iraqi children is poor as most of them progressed to CRF because of the non-availability of cysteamine. Keywords: Fanconi syndrome--Nephropathic -Cystinosis

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August 2006
8 Reads

Continuous renal replacement in the developing world: Is there any alternative.

Authors:
Aamir Al Mosawi

Therapy (London) 2006:3(2): 265-272. Th

Therapy

Background: Dialysis and renal-replacement therapy (RRT) through transplantation were originally developed in an effort to prolong life in patients with end-stage renal failure. However, they have since become common management practice in developed countries. In areas in the developing world where RRT has been introduced to some extent (e.g., hemodialysis and transplantation), despite the lack of effective and skilled teams, rehabilitation is commonly unsatisfactory and results are discouraging relative to costs. Patients undergoing RRT in these areas commonly experience a disproportionate amount of discomfort and suffering which cannot be balanced by the added length of life achieved. Aim: To lower urea elevations in patients with chronic renal failure and symptomatic uremia who were reluctant to undergo dialysis, and to achieve improved wellbeing without dialysis by the use of this novel form of RRT consisting of acacia gum supplementation and a low-protein diet. Patients & methods: From June 2001 to October 2005, 43 patients consisting of 29 males (69%) and 14 females (31%), with symptomatic uremia were referred for treatment due to their unwillingness to undergo dialysis. Ages ranged from 18 months to 81 years. All patients considered dialysis in their circumstance to be associated with an unacceptable degree of discomfort and suffering. No patient presented with a life-threatening uremic complication on referral. All patients were educated regarding the risks of uremia in the absence of maintenance dialysis. Only patients who attended the evaluation visits within 2–3 weeks with an acceptable degree of adherence to the therapeutic protocol were enrolled. It was thus possible to follow 11 patients for 2–16 weeks. Results: All 11 patients enrolled experienced amelioration of symptoms of uremia with improved general wellbeing in association with lowering of urea levels and creatinine during the period of therapy. It was possible to provide hemodialysis freedom to two patients. Conclusion: This is the first study reporting the use of acacia gum in adults with symptomatic uremia, and the first reporting hemodialysis freedom in patients with end-stage renal failure.

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March 2006
8 Reads

A possible role of essential oil terpenes in the management of childhood Urolithiasis.

Authors:
Aamir Al Mosawi

Therapy 2005; 2(2):243-247.

Therapy

Background: Most treatments for childhood urolithiasis are preventive, and conservative management such as chemical dissolution has its limitations. As a result, open surgery is still required in childhood lithiasis. With lithotripsy, repeated sessions are often required, a uretral stent may be required and the shock wave may damage the renal parenchyma, particularly when nephrocalcinosis is present. Some authors have reported the disappearance of radiological-proven calculi in adult patients in association with the use of nontoxic terpenes, the essential oils contained in the roots, seeds and leaves of various plants. Patients & methods: From January 2001 to November 2004, 6 patients (5 males and 1 female) with ultrasonographically proven renal or uretral stones were enrolled in a clinical study investigating the possibility of using terpene oily capsules in the management of childhood urolithiasis. A total of 4 children had hypercalciuria and 2 had hyperoxaluria and distal renal tubular acidosis. Their ages ranged from 10 months to 5 years. They received traditional treatments for the underlying metabolic abnormalities, such as hypocalciuric diuretics for hypercalciuria. Aim: To provide children with sonographically proven urolithiasis, a stone-free state by the addition of essential oil capsules of the terpenic type to traditional preventive therapies. They received these therapies for a period ranging from 10 days to 12 weeks. Results: All patients achieved a stone-free state without the occurrence of any adverse effects. Conclusion: Terpenes may be of benefit in the management of childhood urolithiasis. A study enrolling a larger number of patients investigating the efficacy of these terpenes in the management of childhood urolithiasis is recommended as the small number of patients in this study preclude a definite conclusion.

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March 2005
8 Reads

Acacia gum supplementation of a low-protein diet in children with end-stage renal disease.

Pediatr Nephrol 2004 Oct 4;19(10):1156-9. Epub 2004 Aug 4.

Department of Pediatrics, University Hospital Al-Kadhimiya, Al-Kadhimiya, P.O. Box 70025, Baghdad, Iraq.

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http://dx.doi.org/10.1007/s00467-004-1562-5DOI Listing
October 2004
7 Reads
2 Citations
2.860 Impact Factor

The etiology of chronic renal failure in 54 Iraqi children.

Pediatr Nephrol 2002 Jun;17(6):463-4

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June 2002
7 Reads
2.860 Impact Factor

The challenge of chronic renal failure in the developing world: possible use of acacia gum.

Authors:
A J Al-Mosawi

Pediatr Nephrol 2002 May;17(5):390-1

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http://dx.doi.org/10.1007/s00467-001-0755-4DOI Listing
May 2002
8 Reads
2.860 Impact Factor

The pattern of acute glomerulonephritis in 47 Iraqi children.

Pediatr Nephrol 2002 Jan;17(1):74-5

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http://dx.doi.org/10.1007/s004670200016DOI Listing
January 2002
7 Reads
2.860 Impact Factor

Acacia gum therapeutic potential: possible role in the management of uremia – a new potential medicine.

Authors:
Aamir Al Mosawi

Therapy, 2006; 3(2) 301-321. Therapy, 2006; 3(2) 301-32

Therapy

SUPPLEMENT Acacia gum therapeutic potential: possible role in the management of uremia – a new potential medicine

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9 Reads