Aalim M Weljie

Aalim M Weljie

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Aalim M Weljie

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Fructose-1,6-Bisphosphatase 2 Inhibits Sarcoma Progression by Restraining Mitochondrial Biogenesis.

Cell Metab 2020 Jan 21;31(1):174-188.e7. Epub 2019 Nov 21.

Abramson Family Cancer Research Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Cell and Development Biology, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2019.10.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949384PMC
January 2020

Targeting glutamine metabolism slows soft tissue sarcoma growth.

Nat Commun 2020 Jan 24;11(1):498. Epub 2020 Jan 24.

Abramson Family Cancer Research Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1038/s41467-020-14374-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981153PMC
January 2020

NMR Spectroscopy-Based Metabolic Profiling of Biospecimens.

Curr Protoc Protein Sci 2019 Dec;98(1):e98

Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1002/cpps.98DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884008PMC
December 2019

Metabolism of sleep and aging: Bridging the gap using metabolomics.

Nutr Healthy Aging 2019 Dec 19;5(3):167-184. Epub 2019 Dec 19.

Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.3233/NHA-180043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971829PMC
December 2019

Misregulation of Drosophila Myc Disrupts Circadian Behavior and Metabolism.

Cell Rep 2019 Nov;29(7):1778-1788.e4

Ludwig Institute for Cancer Research, New York, NY 10017, USA; The Wistar Institute, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.10.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910219PMC
November 2019

Cyclooxygenase-2, Asymmetric Dimethylarginine, and the Cardiovascular Hazard From Nonsteroidal Anti-Inflammatory Drugs.

Circulation 2018 11;138(21):2367-2378

Department of Systems Pharmacology and Translational Therapeutics and the Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, Philadelphia, PA (E.R., S.Y.T., D.M., S.D.R., H.M., X.L., N.F.L., A.M.W., G.A.F.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.033540DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291350PMC
November 2018

Circadian- and Light-driven Metabolic Rhythms in Drosophila melanogaster.

J Biol Rhythms 2018 04 21;33(2):126-136. Epub 2018 Jan 21.

Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1177/0748730417753003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692290PMC
April 2018

Sleep restriction induced energy, methylation and lipogenesis metabolic switches in rat liver.

Int J Biochem Cell Biol 2017 12 30;93:129-135. Epub 2017 Aug 30.

Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, 3400 Civic Center Boulevard, Philadelphia, PA 19104, United States; Institute of Translational Medicine and Therapeutics, University of Pennsylvania, 3400 Civic Center Boulevard, Philadelphia, PA 19104, United States. Electronic address:

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http://dx.doi.org/10.1016/j.biocel.2017.08.014DOI Listing
December 2017

A Pilot Characterization of the Human Chronobiome.

Sci Rep 2017 12 7;7(1):17141. Epub 2017 Dec 7.

Department of Systems Pharmacology and Translational Therapeutics, at the University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1038/s41598-017-17362-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719427PMC
December 2017

Nuclear Acetyl-CoA Production by ACLY Promotes Homologous Recombination.

Mol Cell 2017 Jul 6;67(2):252-265.e6. Epub 2017 Jul 6.

Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.06.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580398PMC
July 2017

Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism.

Cell Metab 2017 Apr;25(4):961-974.e4

Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Institute of Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://www.cell.com/cell-metabolism/pdf/S1550-4131(17)30171-
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http://linkinghub.elsevier.com/retrieve/pii/S155041311730171
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http://dx.doi.org/10.1016/j.cmet.2017.03.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479132PMC
April 2017

Plasma metabolomics for the diagnosis and prognosis of H1N1 influenza pneumonia.

Crit Care 2017 Apr 19;21(1):97. Epub 2017 Apr 19.

Department of Critical Care Medicine, University of Calgary, Calgary, AB, Canada.

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http://dx.doi.org/10.1186/s13054-017-1672-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397800PMC
April 2017

Time is ripe: maturation of metabolomics in chronobiology.

Curr Opin Biotechnol 2017 02 1;43:70-76. Epub 2016 Oct 1.

Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, United States; Institute of Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States. Electronic address:

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http://dx.doi.org/10.1016/j.copbio.2016.09.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305625PMC
February 2017

ACSS2-mediated acetyl-CoA synthesis from acetate is necessary for human cytomegalovirus infection.

Proc Natl Acad Sci U S A 2017 02 6;114(8):E1528-E1535. Epub 2017 Feb 6.

Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104;

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http://dx.doi.org/10.1073/pnas.1614268114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338361PMC
February 2017

A quantitative metabolomics profiling approach for the noninvasive assessment of liver histology in patients with chronic hepatitis C.

Clin Transl Med 2016 Dec 18;5(1):33. Epub 2016 Aug 18.

Metabolomics Research Center, Department of Biological Sciences, University of Calgary, Calgary, AB, T2N 1N4, Canada.

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http://dx.doi.org/10.1186/s40169-016-0109-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990529PMC
December 2016

Comprehensive Optimization of LC-MS Metabolomics Methods Using Design of Experiments (COLMeD).

Metabolomics 2016 Dec 24;12(12). Epub 2016 Oct 24.

Department of Systems Pharmacology and Translational Therapeutics, Institute for Translational Medicine and Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.

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http://dx.doi.org/10.1007/s11306-016-1132-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364801PMC
December 2016

ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch.

Cell Rep 2016 10;17(4):1037-1052

Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.09.069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175409PMC
October 2016

Deciphering the Duality of Clock and Growth Metabolism in a Cell Autonomous System Using NMR Profiling of the Secretome.

Metabolites 2016 Jul 27;6(3). Epub 2016 Jul 27.

Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041122PMC
http://dx.doi.org/10.3390/metabo6030023DOI Listing
July 2016

A Pilot Study on the Utility of Serum Metabolomics in Neuroblastoma Patients and Xenograft Models.

Pediatr Blood Cancer 2016 Feb 20;63(2):214-20. Epub 2015 Oct 20.

Department of Oncology, University of Calgary, Canada.

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http://dx.doi.org/10.1002/pbc.25784DOI Listing
February 2016

Comparative metabolomics in vegans and omnivores reveal constraints on diet-dependent gut microbiota metabolite production.

Gut 2016 Jan 26;65(1):63-72. Epub 2014 Nov 26.

Division of Gastroenterology, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, Pennsylvania, USA Departments of Biostatistics & Epidemiology, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1136/gutjnl-2014-308209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583329PMC
January 2016

MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells.

Cell Metab 2015 Dec 17;22(6):1009-19. Epub 2015 Sep 17.

Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Division of Hematology-Oncology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2015.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818967PMC
December 2015

Metabolic analysis of knee synovial fluid as a potential diagnostic approach for osteoarthritis.

J Orthop Res 2015 Nov 12;33(11):1631-8. Epub 2015 Jun 12.

Department of Biological Sciences, Bio-NMR-Centre, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1002/jor.22949DOI Listing
November 2015

Metabolomics reveals differences of metal toxicity in cultures of Pseudomonas pseudoalcaligenes KF707 grown on different carbon sources.

Front Microbiol 2015 17;6:827. Epub 2015 Aug 17.

Department of Biological Sciences, University of Calgary, Calgary AB, Canada ; Biofilm Research Group, University of Calgary, Calgary AB, Canada.

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http://dx.doi.org/10.3389/fmicb.2015.00827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538868PMC
September 2015

Independent Effects of γ-Aminobutyric Acid Transaminase (GABAT) on Metabolic and Sleep Homeostasis.

J Biol Chem 2015 Aug 29;290(33):20407-16. Epub 2015 Jun 29.

From the Departments of Neuroscience and the Howard Hughes Medical Institute, Chevy Chase, Maryland 20815-6789, and the Department of Cell and Molecular Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6064

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http://www.jbc.org/lookup/doi/10.1074/jbc.M114.602276
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http://dx.doi.org/10.1074/jbc.M114.602276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536446PMC
August 2015

Targeted cancer therapeutics: biosynthetic and energetic pathways characterized by metabolomics and the interplay with key cancer regulatory factors.

Curr Pharm Des 2014 ;20(15):2637-47

Department of Pharmacology, University of Pennsylvania, Smilow Center for Translational Research, 3400 Civic Center Blvd, Bldg 421, Room 10-113, Philadelphia, Pennsylvania, USA 19104.

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http://dx.doi.org/10.2174/13816128113199990489DOI Listing
February 2015

Oxalic acid and diacylglycerol 36:3 are cross-species markers of sleep debt.

Proc Natl Acad Sci U S A 2015 Feb 9;112(8):2569-74. Epub 2015 Feb 9.

Program in Chronobiology, Howard Hughes Medical Institute, University of Pennsylvania, Philadelphia, PA 19104; and

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http://dx.doi.org/10.1073/pnas.1417432112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345602PMC
February 2015

Computational tools for the secondary analysis of metabolomics experiments.

Comput Struct Biotechnol J 2013 6;4:e201301003. Epub 2013 Feb 6.

Department of Biological Sciences, University of Calgary, Calgary, AB. 2500 University Dr. NW, Calgary, Alberta, T2N 1N4, Canada.

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http://dx.doi.org/10.5936/csbj.201301003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962093PMC
June 2014

Evaluation of extraction protocols for simultaneous polar and non-polar yeast metabolite analysis using multivariate projection methods.

Metabolites 2013 Jul 23;3(3):592-605. Epub 2013 Jul 23.

Department of Biological Sciences, University of Calgary, 2500 University Drive NW, Calgary T2N 1N4, AB, Canada.

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http://dx.doi.org/10.3390/metabo3030592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901283PMC
July 2013

Satiety hormone and metabolomic response to an intermittent high energy diet differs in rats consuming long-term diets high in protein or prebiotic fiber.

J Proteome Res 2012 Aug 23;11(8):4065-74. Epub 2012 Jul 23.

Department of Biochemistry and Molecular Biology, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta, T2N 4N1, Canada.

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http://dx.doi.org/10.1021/pr300487sDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411197PMC
August 2012

Serum metabolomic profile as a means to distinguish stage of colorectal cancer.

Genome Med 2012 May 14;4(5):42. Epub 2012 May 14.

Department of Surgery, University of Calgary, 3330 Hospital Dr NW, Calgary, AB, Canada, T2N 4N1.

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http://dx.doi.org/10.1186/gm341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506908PMC
May 2012

Elevated physiological levels of folic acid can increase in vitro growth and invasiveness of prostate cancer cells.

BJU Int 2012 Mar 19;109(5):788-95. Epub 2011 Jul 19.

Department of Pathology and Laboratory Medicine, University of Calgary and Calgary Laboratory Services, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1111/j.1464-410X.2011.10437.xDOI Listing
March 2012

Environmental contaminant mixtures at ambient concentrations invoke a metabolic stress response in goldfish not predicted from exposure to individual compounds alone.

J Proteome Res 2012 Feb 29;11(2):1133-43. Epub 2011 Dec 29.

Department of Biological Sciences and ‡Institute of Environmental Toxicology 2500 University Drive NW, University of Calgary, Calgary, Alberta, Canada T2N 1N4.

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http://dx.doi.org/10.1021/pr200840bDOI Listing
February 2012

Metabolomics and its application to studying metal toxicity.

Metallomics 2011 Nov 16;3(11):1142-52. Epub 2011 Sep 16.

Department of Biological Sciences, Faculty of Science, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1039/c1mt00070eDOI Listing
November 2011

Hypoxia-induced metabolic shifts in cancer cells: moving beyond the Warburg effect.

Int J Biochem Cell Biol 2011 Jul 24;43(7):981-9. Epub 2010 Aug 24.

Department of Biological Sciences, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1016/j.biocel.2010.08.009DOI Listing
July 2011

Differences in metabolism between the biofilm and planktonic response to metal stress.

J Proteome Res 2011 Jul 31;10(7):3190-9. Epub 2011 May 31.

Department of Biological Sciences, University of Calgary, Calgary, AB, Canada T2N 1N4.

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http://pubs.acs.org/doi/abs/10.1021/pr2002353
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http://dx.doi.org/10.1021/pr2002353DOI Listing
July 2011

Metabolomic response to exercise training in lean and diet-induced obese mice.

J Appl Physiol (1985) 2011 May 26;110(5):1311-8. Epub 2011 Jan 26.

Department of Biological Sciences, Bio-NMR Center, Faculty of Science, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1152/japplphysiol.00701.2010DOI Listing
May 2011

(1)H NMR metabolomics identification of markers of hypoxia-induced metabolic shifts in a breast cancer model system.

J Biomol NMR 2011 Apr 4;49(3-4):185-93. Epub 2011 Mar 4.

Department of Biological Sciences, University of Calgary, 2500 University Dr. NW, Calgary, AB, T2N 1N4, Canada.

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http://link.springer.com/10.1007/s10858-011-9486-4
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http://dx.doi.org/10.1007/s10858-011-9486-4DOI Listing
April 2011

Feasibility of identifying pancreatic cancer based on serum metabolomics.

Cancer Epidemiol Biomarkers Prev 2011 Jan 23;20(1):140-7. Epub 2010 Nov 23.

Department of Surgery, University of Calgary, Calgary, Alberta, Canada.

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http://cebp.aacrjournals.org/cgi/doi/10.1158/1055-9965.EPI-1
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http://dx.doi.org/10.1158/1055-9965.EPI-10-0712DOI Listing
January 2011

A global metabolic shift is linked to Salmonella multicellular development.

PLoS One 2010 Jul 27;5(7):e11814. Epub 2010 Jul 27.

Department of Microbiology and Infectious Diseases, University of Calgary, Calgary, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0011814PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910731PMC
July 2010

Phenotypic and metabolic profiling of colony morphology variants evolved from Pseudomonas fluorescens biofilms.

Environ Microbiol 2010 Jun 3;12(6):1565-77. Epub 2010 Mar 3.

Biofilm Research Group, University of Calgary, 2500 University Dr NW, Calgary, AB, Canada, T2N 1N4.

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http://doi.wiley.com/10.1111/j.1462-2920.2010.02185.x
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http://dx.doi.org/10.1111/j.1462-2920.2010.02185.xDOI Listing
June 2010

Quality assessment of ginseng by (1)H NMR metabolite fingerprinting and profiling analysis.

J Agric Food Chem 2009 Aug;57(16):7513-22

Department of Biological Sciences, University of Calgary, Alberta, Canada.

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http://dx.doi.org/10.1021/jf901675yDOI Listing
August 2009

Metabolic footprinting study of white spruce somatic embryogenesis using NMR spectroscopy.

Plant Physiol Biochem 2009 May 10;47(5):343-50. Epub 2009 Jan 10.

Metabolomics Research Centre, University of Calgary, Alberta, Canada.

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http://dx.doi.org/10.1016/j.plaphy.2008.12.023DOI Listing
May 2009

Metabolomic investigation of the bacterial response to a metal challenge.

Appl Environ Microbiol 2009 Feb 1;75(3):719-28. Epub 2008 Dec 1.

Department of Biological Sciences, University of Calgary, Alberta, Canada.

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http://dx.doi.org/10.1128/AEM.01771-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632130PMC
February 2009

Evaluating low-intensity unknown signals in quantitative proton NMR mixture analysis.

Anal Chem 2008 Dec;80(23):8956-65

Metabolomics Research Centre, Department of Biological Sciences, McCaig Institute for Bone and Joint Health, University of Calgary, Alberta, Canada.

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http://dx.doi.org/10.1021/ac8012362DOI Listing
December 2008

Quantitative 1H nuclear magnetic resonance metabolite profiling as a functional genomics platform to investigate alkaloid biosynthesis in opium poppy.

Plant Physiol 2008 Aug 11;147(4):1805-21. Epub 2008 Jun 11.

Department of Biological Sciences, University of Calgary, Calgary, Alberta, Canada T2N 1N4.

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http://dx.doi.org/10.1104/pp.108.120493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2492654PMC
August 2008

Quantitative 1H NMR metabolomics reveals extensive metabolic reprogramming of primary and secondary metabolism in elicitor-treated opium poppy cell cultures.

BMC Plant Biol 2008 Jan 22;8. Epub 2008 Jan 22.

Department of Biological Sciences, University of Calgary, Calgary, Alberta, T2N 1N4, Canada.

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http://dx.doi.org/10.1186/1471-2229-8-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2257952PMC
January 2008

An inflammatory arthritis-associated metabolite biomarker pattern revealed by 1H NMR spectroscopy.

J Proteome Res 2007 Sep 15;6(9):3456-64. Epub 2007 Aug 15.

Metabolomics Research Centre, Department of Biological Sciences, Department of Biochemistry and Molecular Biology, and the McCaig Institute for Bone and Joint Health, University of Calgary, Calgary, Alberta T2N 4N1, Canada.

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http://dx.doi.org/10.1021/pr070123jDOI Listing
September 2007

Investigations of the effects of gender, diurnal variation, and age in human urinary metabolomic profiles.

Anal Chem 2007 Sep 17;79(18):6995-7004. Epub 2007 Aug 17.

Department of Medicine and Magnetic Resonance Diagnostic Centre, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1021/ac0708588DOI Listing
September 2007

Targeted profiling: quantitative analysis of 1H NMR metabolomics data.

Anal Chem 2006 Jul;78(13):4430-42

Chenomx Inc., Edmonton, Alberta, Canada, and Metabolomics Research Centre, University of Calgary, Calgary, Canada.

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http://dx.doi.org/10.1021/ac060209gDOI Listing
July 2006

The solution structure of the C-terminal domain of TonB and interaction studies with TonB box peptides.

J Mol Biol 2005 Feb 15;345(5):1185-97. Epub 2004 Dec 15.

Department of Biological Sciences, University of Calgary, 2500 University Drive N.W., Calgary, AB, Canada T2N 1N4.

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http://linkinghub.elsevier.com/retrieve/pii/S002228360401465
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http://dx.doi.org/10.1016/j.jmb.2004.11.026DOI Listing
February 2005

Solution structure and backbone dynamics of the N-terminal region of the calcium regulatory domain from soybean calcium-dependent protein kinase alpha.

Biochemistry 2004 Dec;43(48):15131-40

Structural Biology Research Group, Department of Biological Sciences, University of Calgary, 2500 University Drive NW, Calgary, Alberta, Canada T2N 1N4.

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http://dx.doi.org/10.1021/bi048751rDOI Listing
December 2004

Unexpected structure of the Ca2+-regulatory region from soybean calcium-dependent protein kinase-alpha.

J Biol Chem 2004 Aug 20;279(34):35494-502. Epub 2004 May 20.

Structural Biology Research Group, Department of Biological Sciences, University of Calgary, 2500 University Dr. N. W., Calgary, Alberta T2N 1N4, Canada.

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http://dx.doi.org/10.1074/jbc.M311520200DOI Listing
August 2004

Backbone dynamic properties of the central linker region of calcium-calmodulin in 35% trifluoroethanol.

J Struct Biol 2004 Jun;146(3):272-80

Structural Biology Research Group, Department of Biological Sciences, University of Calgary, 2500 University Dr. N.W., Calgary, Alta., Canada T2N 1N4.

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http://linkinghub.elsevier.com/retrieve/pii/S104784770300320
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http://dx.doi.org/10.1016/j.jsb.2003.12.007DOI Listing
June 2004

Conformational changes in the Ca2+-regulatory region from soybean calcium-dependent protein kinase-alpha: fluorescence resonance energy transfer studies.

J Biol Chem 2003 Oct 26;278(44):43764-9. Epub 2003 Aug 26.

Structural Biology Research Group, Department of Biological Sciences, University of Calgary, Alberta T2N 1N4, Canada.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M306799200
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http://dx.doi.org/10.1074/jbc.M306799200DOI Listing
October 2003

Protein conformational changes studied by diffusion NMR spectroscopy: application to helix-loop-helix calcium binding proteins.

Protein Sci 2003 Feb;12(2):228-36

Structural Biology Research Group, Department of Biological Sciences, University of Calgary, Alberta, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2312419PMC
http://dx.doi.org/10.1110/ps.0226203DOI Listing
February 2003

Molecular properties of the putative nitrogen sensor PII from Arabidopsis thaliana.

Plant J 2003 Jan;33(2):353-60

Department of Biological Sciences, University of Calgary, 2500 University Drive NW, Calgary, Alberta, Canada T2N 1N4.

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http://dx.doi.org/10.1046/j.1365-313x.2003.01634.xDOI Listing
January 2003

Exploring familial relationships using multiple sequence alignment.

Methods Mol Biol 2002 ;173:231-53

Department of Biological Sciences, University of Calgary, Calgary, AB, Canada.

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http://dx.doi.org/10.1385/1-59259-184-1:231DOI Listing
August 2002

Steady-state fluorescence spectroscopy.

Methods Mol Biol 2002 ;173:75-87

Department of Biological Sciences, University of Calgary, Calgary, AB, Canada.

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http://dx.doi.org/10.1385/1-59259-184-1:075DOI Listing
August 2002

Solution structures of the cytoplasmic tail complex from platelet integrin alpha IIb- and beta 3-subunits.

Proc Natl Acad Sci U S A 2002 Apr;99(9):5878-83

Department of Biological Sciences, University of Calgary, 2500 University Drive NW, Calgary, AB, Canada.

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http://www.pnas.org/cgi/doi/10.1073/pnas.092515799
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http://dx.doi.org/10.1073/pnas.092515799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC122870PMC
April 2002