Publications by authors named "Aage Haugen"

84Publications

Publisher Correction: Shared heritability and functional enrichment across six solid cancers.

Authors:
Xia Jiang Hilary K Finucane Fredrick R Schumacher Stephanie L Schmit Jonathan P Tyrer Younghun Han Kyriaki Michailidou Corina Lesseur Karoline B Kuchenbaecker Joe Dennis David V Conti Graham Casey Mia M Gaudet Jeroen R Huyghe Demetrius Albanes Melinda C Aldrich Angeline S Andrew Irene L Andrulis Hoda Anton-Culver Antonis C Antoniou Natalia N Antonenkova Susanne M Arnold Kristan J Aronson Banu K Arun Elisa V Bandera Rosa B Barkardottir Daniel R Barnes Jyotsna Batra Matthias W Beckmann Javier Benitez Sara Benlloch Andrew Berchuck Sonja I Berndt Heike Bickeböller Stephanie A Bien Carl Blomqvist Stefania Boccia Natalia V Bogdanova Stig E Bojesen Manjeet K Bolla Hiltrud Brauch Hermann Brenner James D Brenton Mark N Brook Joan Brunet Hans Brunnström Daniel D Buchanan Barbara Burwinkel Ralf Butzow Gabriella Cadoni Trinidad Caldés Maria A Caligo Ian Campbell Peter T Campbell Géraldine Cancel-Tassin Lisa Cannon-Albright Daniele Campa Neil Caporaso André L Carvalho Andrew T Chan Jenny Chang-Claude Stephen J Chanock Chu Chen David C Christiani Kathleen B M Claes Frank Claessens Judith Clements J Margriet Collée Marcia Cruz Correa Fergus J Couch Angela Cox Julie M Cunningham Cezary Cybulski Kamila Czene Mary B Daly Anna deFazio Peter Devilee Orland Diez Manuela Gago-Dominguez Jenny L Donovan Thilo Dörk Eric J Duell Alison M Dunning Miriam Dwek Diana M Eccles Christopher K Edlund Digna R Velez Edwards Carolina Ellberg D Gareth Evans Peter A Fasching Robert L Ferris Triantafillos Liloglou Jane C Figueiredo Olivia Fletcher Renée T Fortner Florentia Fostira Silvia Franceschi Eitan Friedman Steven J Gallinger Patricia A Ganz Judy Garber José A García-Sáenz Simon A Gayther Graham G Giles Andrew K Godwin Mark S Goldberg David E Goldgar Ellen L Goode Marc T Goodman Gary Goodman Kjell Grankvist Mark H Greene Henrik Gronberg Jacek Gronwald Pascal Guénel Niclas Håkansson Per Hall Ute Hamann Freddie C Hamdy Robert J Hamilton Jochen Hampe Aage Haugen Florian Heitz Rolando Herrero Peter Hillemanns Michael Hoffmeister Estrid Høgdall Yun-Chul Hong John L Hopper Richard Houlston Peter J Hulick David J Hunter David G Huntsman Gregory Idos Evgeny N Imyanitov Sue Ann Ingles Claudine Isaacs Anna Jakubowska Paul James Mark A Jenkins Mattias Johansson Mikael Johansson Esther M John Amit D Joshi Radka Kaneva Beth Y Karlan Linda E Kelemen Tabea Kühl Kay-Tee Khaw Elza Khusnutdinova Adam S Kibel Lambertus A Kiemeney Jeri Kim Susanne K Kjaer Julia A Knight Manolis Kogevinas Zsofia Kote-Jarai Stella Koutros Vessela N Kristensen Jolanta Kupryjanczyk Martin Lacko Stephan Lam Diether Lambrechts Maria Teresa Landi Philip Lazarus Nhu D Le Eunjung Lee Flavio Lejbkowicz Heinz-Josef Lenz Goska Leslie Davor Lessel Jenny Lester Douglas A Levine Li Li Christopher I Li Annika Lindblom Noralane M Lindor Geoffrey Liu Fotios Loupakis Jan Lubiński Lovise Maehle Christiane Maier Arto Mannermaa Loic Le Marchand Sara Margolin Taymaa May Lesley McGuffog Alfons Meindl Pooja Middha Austin Miller Roger L Milne Robert J MacInnis Francesmary Modugno Marco Montagna Victor Moreno Kirsten B Moysich Lorelei Mucci Kenneth Muir Anna Marie Mulligan Katherine L Nathanson David E Neal Andrew R Ness Susan L Neuhausen Heli Nevanlinna Polly A Newcomb Lisa F Newcomb Finn Cilius Nielsen Liene Nikitina-Zake Børge G Nordestgaard Robert L Nussbaum Kenneth Offit Edith Olah Ali Amin Al Olama Olufunmilayo I Olopade Andrew F Olshan Håkan Olsson Ana Osorio Hardev Pandha Jong Y Park Nora Pashayan Michael T Parsons Tanja Pejovic Kathryn L Penney Wilbert H M Peters Catherine M Phelan Amanda I Phipps Dijana Plaseska-Karanfilska Miranda Pring Darya Prokofyeva Paolo Radice Kari Stefansson Susan J Ramus Leon Raskin Gad Rennert Hedy S Rennert Elizabeth J van Rensburg Marjorie J Riggan Harvey A Risch Angela Risch Monique J Roobol Barry S Rosenstein Mary Anne Rossing Kim De Ruyck Emmanouil Saloustros Dale P Sandler Elinor J Sawyer Matthew B Schabath Johanna Schleutker Marjanka K Schmidt V Wendy Setiawan Hongbing Shen Erin M Siegel Weiva Sieh Christian F Singer Martha L Slattery Karina Dalsgaard Sorensen Melissa C Southey Amanda B Spurdle Janet L Stanford Victoria L Stevens Sebastian Stintzing Jennifer Stone Karin Sundfeldt Rebecca Sutphen Anthony J Swerdlow Eloiza H Tajara Catherine M Tangen Adonina Tardon Jack A Taylor M Dawn Teare Manuel R Teixeira Mary Beth Terry Kathryn L Terry Stephen N Thibodeau Mads Thomassen Line Bjørge Marc Tischkowitz Amanda E Toland Diana Torres Paul A Townsend Ruth C Travis Nadine Tung Shelley S Tworoger Cornelia M Ulrich Nawaid Usmani Celine M Vachon Els Van Nieuwenhuysen Ana Vega Miguel Elías Aguado-Barrera Qin Wang Penelope M Webb Clarice R Weinberg Stephanie Weinstein Mark C Weissler Jeffrey N Weitzel Catharine M L West Emily White Alice S Whittemore H-Erich Wichmann Fredrik Wiklund Robert Winqvist Alicja Wolk Penella Woll Michael Woods Anna H Wu Xifeng Wu Drakoulis Yannoukakos Wei Zheng Shanbeh Zienolddiny Argyrios Ziogas Kristin K Zorn Jacqueline M Lane Richa Saxena Duncan Thomas Rayjean J Hung Brenda Diergaarde James McKay Ulrike Peters Li Hsu Montserrat García-Closas Rosalind A Eeles Georgia Chenevix-Trench Paul J Brennan Christopher A Haiman Jacques Simard Douglas F Easton Stephen B Gruber Paul D P Pharoah Alkes L Price Bogdan Pasaniuc Christopher I Amos Peter Kraft Sara Lindström

Nat Commun 2019 Sep 23;10(1):4386. Epub 2019 Sep 23.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Seattle, WA, 98109-1024, USA.

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http://dx.doi.org/10.1038/s41467-019-12095-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757065PMC
September 2019

Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 515.33 TERT-CLPTM1Ll Region.

J Thorac Oncol 2019 08 19;14(8):1360-1369. Epub 2019 Apr 19.

Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15560864193028
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http://dx.doi.org/10.1016/j.jtho.2019.04.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6833942PMC
August 2019

Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development.

Oncotarget 2019 Mar 5;10(19):1760-1774. Epub 2019 Mar 5.

Biomedical Data Science Department, Dartmouth College, Hanover, NH, USA.

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http://dx.doi.org/10.18632/oncotarget.26678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442994PMC
March 2019

Elevated Platelet Count Appears to Be Causally Associated with Increased Risk of Lung Cancer: A Mendelian Randomization Analysis.

Cancer Epidemiol Biomarkers Prev 2019 05 30;28(5):935-942. Epub 2019 Jan 30.

Department of Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1158/1055-9965.EPI-18-0356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7075698PMC
May 2019

Shared heritability and functional enrichment across six solid cancers.

Authors:
Xia Jiang Hilary K Finucane Fredrick R Schumacher Stephanie L Schmit Jonathan P Tyrer Younghun Han Kyriaki Michailidou Corina Lesseur Karoline B Kuchenbaecker Joe Dennis David V Conti Graham Casey Mia M Gaudet Jeroen R Huyghe Demetrius Albanes Melinda C Aldrich Angeline S Andrew Irene L Andrulis Hoda Anton-Culver Antonis C Antoniou Natalia N Antonenkova Susanne M Arnold Kristan J Aronson Banu K Arun Elisa V Bandera Rosa B Barkardottir Daniel R Barnes Jyotsna Batra Matthias W Beckmann Javier Benitez Sara Benlloch Andrew Berchuck Sonja I Berndt Heike Bickeböller Stephanie A Bien Carl Blomqvist Stefania Boccia Natalia V Bogdanova Stig E Bojesen Manjeet K Bolla Hiltrud Brauch Hermann Brenner James D Brenton Mark N Brook Joan Brunet Hans Brunnström Daniel D Buchanan Barbara Burwinkel Ralf Butzow Gabriella Cadoni Trinidad Caldés Maria A Caligo Ian Campbell Peter T Campbell Géraldine Cancel-Tassin Lisa Cannon-Albright Daniele Campa Neil Caporaso André L Carvalho Andrew T Chan Jenny Chang-Claude Stephen J Chanock Chu Chen David C Christiani Kathleen B M Claes Frank Claessens Judith Clements J Margriet Collée Marcia Cruz Correa Fergus J Couch Angela Cox Julie M Cunningham Cezary Cybulski Kamila Czene Mary B Daly Anna deFazio Peter Devilee Orland Diez Manuela Gago-Dominguez Jenny L Donovan Thilo Dörk Eric J Duell Alison M Dunning Miriam Dwek Diana M Eccles Christopher K Edlund Digna R Velez Edwards Carolina Ellberg D Gareth Evans Peter A Fasching Robert L Ferris Triantafillos Liloglou Jane C Figueiredo Olivia Fletcher Renée T Fortner Florentia Fostira Silvia Franceschi Eitan Friedman Steven J Gallinger Patricia A Ganz Judy Garber José A García-Sáenz Simon A Gayther Graham G Giles Andrew K Godwin Mark S Goldberg David E Goldgar Ellen L Goode Marc T Goodman Gary Goodman Kjell Grankvist Mark H Greene Henrik Gronberg Jacek Gronwald Pascal Guénel Niclas Håkansson Per Hall Ute Hamann Freddie C Hamdy Robert J Hamilton Jochen Hampe Aage Haugen Florian Heitz Rolando Herrero Peter Hillemanns Michael Hoffmeister Estrid Høgdall Yun-Chul Hong John L Hopper Richard Houlston Peter J Hulick David J Hunter David G Huntsman Gregory Idos Evgeny N Imyanitov Sue Ann Ingles Claudine Isaacs Anna Jakubowska Paul James Mark A Jenkins Mattias Johansson Mikael Johansson Esther M John Amit D Joshi Radka Kaneva Beth Y Karlan Linda E Kelemen Tabea Kühl Kay-Tee Khaw Elza Khusnutdinova Adam S Kibel Lambertus A Kiemeney Jeri Kim Susanne K Kjaer Julia A Knight Manolis Kogevinas Zsofia Kote-Jarai Stella Koutros Vessela N Kristensen Jolanta Kupryjanczyk Martin Lacko Stephan Lam Diether Lambrechts Maria Teresa Landi Philip Lazarus Nhu D Le Eunjung Lee Flavio Lejbkowicz Heinz-Josef Lenz Goska Leslie Davor Lessel Jenny Lester Douglas A Levine Li Li Christopher I Li Annika Lindblom Noralane M Lindor Geoffrey Liu Fotios Loupakis Jan Lubiński Lovise Maehle Christiane Maier Arto Mannermaa Loic Le Marchand Sara Margolin Taymaa May Lesley McGuffog Alfons Meindl Pooja Middha Austin Miller Roger L Milne Robert J MacInnis Francesmary Modugno Marco Montagna Victor Moreno Kirsten B Moysich Lorelei Mucci Kenneth Muir Anna Marie Mulligan Katherine L Nathanson David E Neal Andrew R Ness Susan L Neuhausen Heli Nevanlinna Polly A Newcomb Lisa F Newcomb Finn Cilius Nielsen Liene Nikitina-Zake Børge G Nordestgaard Robert L Nussbaum Kenneth Offit Edith Olah Ali Amin Al Olama Olufunmilayo I Olopade Andrew F Olshan Håkan Olsson Ana Osorio Hardev Pandha Jong Y Park Nora Pashayan Michael T Parsons Tanja Pejovic Kathryn L Penney Wilbert H M Peters Catherine M Phelan Amanda I Phipps Dijana Plaseska-Karanfilska Miranda Pring Darya Prokofyeva Paolo Radice Kari Stefansson Susan J Ramus Leon Raskin Gad Rennert Hedy S Rennert Elizabeth J van Rensburg Marjorie J Riggan Harvey A Risch Angela Risch Monique J Roobol Barry S Rosenstein Mary Anne Rossing Kim De Ruyck Emmanouil Saloustros Dale P Sandler Elinor J Sawyer Matthew B Schabath Johanna Schleutker Marjanka K Schmidt V Wendy Setiawan Hongbing Shen Erin M Siegel Weiva Sieh Christian F Singer Martha L Slattery Karina Dalsgaard Sorensen Melissa C Southey Amanda B Spurdle Janet L Stanford Victoria L Stevens Sebastian Stintzing Jennifer Stone Karin Sundfeldt Rebecca Sutphen Anthony J Swerdlow Eloiza H Tajara Catherine M Tangen Adonina Tardon Jack A Taylor M Dawn Teare Manuel R Teixeira Mary Beth Terry Kathryn L Terry Stephen N Thibodeau Mads Thomassen Line Bjørge Marc Tischkowitz Amanda E Toland Diana Torres Paul A Townsend Ruth C Travis Nadine Tung Shelley S Tworoger Cornelia M Ulrich Nawaid Usmani Celine M Vachon Els Van Nieuwenhuysen Ana Vega Miguel Elías Aguado-Barrera Qin Wang Penelope M Webb Clarice R Weinberg Stephanie Weinstein Mark C Weissler Jeffrey N Weitzel Catharine M L West Emily White Alice S Whittemore H-Erich Wichmann Fredrik Wiklund Robert Winqvist Alicja Wolk Penella Woll Michael Woods Anna H Wu Xifeng Wu Drakoulis Yannoukakos Wei Zheng Shanbeh Zienolddiny Argyrios Ziogas Kristin K Zorn Jacqueline M Lane Richa Saxena Duncan Thomas Rayjean J Hung Brenda Diergaarde James McKay Ulrike Peters Li Hsu Montserrat García-Closas Rosalind A Eeles Georgia Chenevix-Trench Paul J Brennan Christopher A Haiman Jacques Simard Douglas F Easton Stephen B Gruber Paul D P Pharoah Alkes L Price Bogdan Pasaniuc Christopher I Amos Peter Kraft Sara Lindström

Nat Commun 2019 01 25;10(1):431. Epub 2019 Jan 25.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Seattle, WA, 98109-1024, USA.

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http://dx.doi.org/10.1038/s41467-018-08054-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347624PMC
January 2019

Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity.

Nat Commun 2018 09 25;9(1):3927. Epub 2018 Sep 25.

International Agency for Research on Cancer, World Health Organization, Lyon, 69372 cedex 08, France.

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http://dx.doi.org/10.1038/s41467-018-05890-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156406PMC
September 2018

Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk.

Authors:
Xuemei Ji Yohan Bossé Maria Teresa Landi Jiang Gui Xiangjun Xiao David Qian Philippe Joubert Maxime Lamontagne Yafang Li Ivan Gorlov Mariella de Biasi Younghun Han Olga Gorlova Rayjean J Hung Xifeng Wu James McKay Xuchen Zong Robert Carreras-Torres David C Christiani Neil Caporaso Mattias Johansson Geoffrey Liu Stig E Bojesen Loic Le Marchand Demetrios Albanes Heike Bickeböller Melinda C Aldrich William S Bush Adonina Tardon Gad Rennert Chu Chen M Dawn Teare John K Field Lambertus A Kiemeney Philip Lazarus Aage Haugen Stephen Lam Matthew B Schabath Angeline S Andrew Hongbing Shen Yun-Chul Hong Jian-Min Yuan Pier A Bertazzi Angela C Pesatori Yuanqing Ye Nancy Diao Li Su Ruyang Zhang Yonathan Brhane Natasha Leighl Jakob S Johansen Anders Mellemgaard Walid Saliba Christopher Haiman Lynne Wilkens Ana Fernandez-Somoano Guillermo Fernandez-Tardon Erik H F M van der Heijden Jin Hee Kim Juncheng Dai Zhibin Hu Michael P A Davies Michael W Marcus Hans Brunnström Jonas Manjer Olle Melander David C Muller Kim Overvad Antonia Trichopoulou Rosario Tumino Jennifer Doherty Gary E Goodman Angela Cox Fiona Taylor Penella Woll Irene Brüske Judith Manz Thomas Muley Angela Risch Albert Rosenberger Kjell Grankvist Mikael Johansson Frances Shepherd Ming-Sound Tsao Susanne M Arnold Eric B Haura Ciprian Bolca Ivana Holcatova Vladimir Janout Milica Kontic Jolanta Lissowska Anush Mukeria Simona Ognjanovic Tadeusz M Orlowski Ghislaine Scelo Beata Swiatkowska David Zaridze Per Bakke Vidar Skaug Shanbeh Zienolddiny Eric J Duell Lesley M Butler Woon-Puay Koh Yu-Tang Gao Richard Houlston John McLaughlin Victoria Stevens David C Nickle Ma'en Obeidat Wim Timens Bin Zhu Lei Song María Soler Artigas Martin D Tobin Louise V Wain Fangyi Gu Jinyoung Byun Ahsan Kamal Dakai Zhu Rachel F Tyndale Wei-Qi Wei Stephen Chanock Paul Brennan Christopher I Amos

Nat Commun 2018 08 13;9(1):3221. Epub 2018 Aug 13.

Biomedical Data Science, Geisel School of Medicine at Dartmouth, Hanover, 03750, NH, USA.

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http://dx.doi.org/10.1038/s41467-018-05074-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089967PMC
August 2018

Mendelian Randomization and mediation analysis of leukocyte telomere length and risk of lung and head and neck cancers.

Int J Epidemiol 2019 06;48(3):751-766

Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1093/ije/dyy140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659464PMC
June 2019

Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population.

Carcinogenesis 2018 03;39(3):336-346

Biomedical Data Science Department, Dartmouth College, Hanover, NH, USA.

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http://dx.doi.org/10.1093/carcin/bgx113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248554PMC
March 2018

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

Authors:
James D McKay Rayjean J Hung Younghun Han Xuchen Zong Robert Carreras-Torres David C Christiani Neil E Caporaso Mattias Johansson Xiangjun Xiao Yafang Li Jinyoung Byun Alison Dunning Karen A Pooley David C Qian Xuemei Ji Geoffrey Liu Maria N Timofeeva Stig E Bojesen Xifeng Wu Loic Le Marchand Demetrios Albanes Heike Bickeböller Melinda C Aldrich William S Bush Adonina Tardon Gad Rennert M Dawn Teare John K Field Lambertus A Kiemeney Philip Lazarus Aage Haugen Stephen Lam Matthew B Schabath Angeline S Andrew Hongbing Shen Yun-Chul Hong Jian-Min Yuan Pier Alberto Bertazzi Angela C Pesatori Yuanqing Ye Nancy Diao Li Su Ruyang Zhang Yonathan Brhane Natasha Leighl Jakob S Johansen Anders Mellemgaard Walid Saliba Christopher A Haiman Lynne R Wilkens Ana Fernandez-Somoano Guillermo Fernandez-Tardon Henricus F M van der Heijden Jin Hee Kim Juncheng Dai Zhibin Hu Michael P A Davies Michael W Marcus Hans Brunnström Jonas Manjer Olle Melander David C Muller Kim Overvad Antonia Trichopoulou Rosario Tumino Jennifer A Doherty Matt P Barnett Chu Chen Gary E Goodman Angela Cox Fiona Taylor Penella Woll Irene Brüske H-Erich Wichmann Judith Manz Thomas R Muley Angela Risch Albert Rosenberger Kjell Grankvist Mikael Johansson Frances A Shepherd Ming-Sound Tsao Susanne M Arnold Eric B Haura Ciprian Bolca Ivana Holcatova Vladimir Janout Milica Kontic Jolanta Lissowska Anush Mukeria Simona Ognjanovic Tadeusz M Orlowski Ghislaine Scelo Beata Swiatkowska David Zaridze Per Bakke Vidar Skaug Shanbeh Zienolddiny Eric J Duell Lesley M Butler Woon-Puay Koh Yu-Tang Gao Richard S Houlston John McLaughlin Victoria L Stevens Philippe Joubert Maxime Lamontagne David C Nickle Ma'en Obeidat Wim Timens Bin Zhu Lei Song Linda Kachuri María Soler Artigas Martin D Tobin Louise V Wain Thorunn Rafnar Thorgeir E Thorgeirsson Gunnar W Reginsson Kari Stefansson Dana B Hancock Laura J Bierut Margaret R Spitz Nathan C Gaddis Sharon M Lutz Fangyi Gu Eric O Johnson Ahsan Kamal Claudio Pikielny Dakai Zhu Sara Lindströem Xia Jiang Rachel F Tyndale Georgia Chenevix-Trench Jonathan Beesley Yohan Bossé Stephen Chanock Paul Brennan Maria Teresa Landi Christopher I Amos

Nat Genet 2017 Jul 12;49(7):1126-1132. Epub 2017 Jun 12.

Biomedical Data Science, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.

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http://dx.doi.org/10.1038/ng.3892DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510465PMC
July 2017

Copy number variation, increased gene expression, and molecular mechanisms of neurofascin in lung cancer.

Mol Carcinog 2017 09 2;56(9):2076-2085. Epub 2017 May 2.

Department of Chemical and Biological Work Environment, National Institute of Occupational Health, Oslo, Norway.

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http://dx.doi.org/10.1002/mc.22664DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084301PMC
September 2017

Estrogen receptor expression and gene promoter methylation in non-small cell lung cancer - a short report.

Cell Oncol (Dordr) 2016 Dec 29;39(6):583-589. Epub 2016 Aug 29.

Section for Toxicology and Biological Working Environment, Department of Biological and Chemical Working Environment, National Institute of Occupational Health, PO box 8149, Dep., Gydas vei 8, N-0033, Oslo, Norway.

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http://dx.doi.org/10.1007/s13402-016-0295-3DOI Listing
December 2016

Epithelial-mesenchymal transition and FOXA genes during tobacco smoke carcinogen induced transformation of human bronchial epithelial cells.

Toxicol In Vitro 2016 Sep 21;35:55-65. Epub 2016 May 21.

Section for Toxicology and Biological Working Environment, Department of Biological and Chemical Working Environment, National Institute of Occupational Health, N-0033 Oslo, Norway. Electronic address:

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http://dx.doi.org/10.1016/j.tiv.2016.04.012DOI Listing
September 2016

Effects of carbon nanotubes on intercellular communication and involvement of IL-1 genes.

J Cell Commun Signal 2016 Jun 21;10(2):153-62. Epub 2016 Apr 21.

Department of Biological and Chemical Work Environment, National Institute of Occupational Health, Pb 8149 Dep, N-0033, Oslo, Norway.

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http://dx.doi.org/10.1007/s12079-016-0323-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882305PMC
June 2016

Loss of MKK3 and MK2 Copy Numbers in Non-Small Cell Lung Cancer.

J Cancer 2016 5;7(5):512-5. Epub 2016 Feb 5.

Section of Toxicology and Biological Work Environment, Department of Biological and Chemical Work Environment, National Institute of Occupational Health, Oslo, Norway.

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http://dx.doi.org/10.7150/jca.13651DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780126PMC
March 2016

Mutations in TP53 increase the risk of SOX2 copy number alterations and silencing of TP53 reduces SOX2 expression in non-small cell lung cancer.

BMC Cancer 2016 Jan 19;16:28. Epub 2016 Jan 19.

Department of Biological and Chemical Work Environment, National Institute of Occupational Health, PO Box 8149 Dep, , N-0033, Oslo, Norway.

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http://dx.doi.org/10.1186/s12885-016-2061-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717590PMC
January 2016

An Integrated Prognostic Classifier for Stage I Lung Adenocarcinoma Based on mRNA, microRNA, and DNA Methylation Biomarkers.

J Thorac Oncol 2015 Jul;10(7):1037-48

*Laboratory of Human Carcinogenesis, NCI-CCR, National Institutes of Health, Bethesda, Maryland; †Division of Molecular Pathology, National Cancer Center Research Institute, Tokyo, Japan; ‡Genetics Branch, NCI-CCR, National Institutes of Health, Bethesda, Maryland; §Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan; ‖Department of Chemical and Biological Working Environment, National Institute of Occupational Health, Oslo, Norway; and ¶Genomics and Epigenomics of Cancer Prediction Program, Institute of Predictive and Personalized Medicine of Cancer (IMPPC), Badalona (Barcelona), Spain.

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http://dx.doi.org/10.1097/JTO.0000000000000560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493931PMC
July 2015

CHRNA5 risk variant predicts delayed smoking cessation and earlier lung cancer diagnosis--a meta-analysis.

J Natl Cancer Inst 2015 May 14;107(5). Epub 2015 Apr 14.

Department of Psychiatry, Washington University School of Medicine, St. Louis, MO (LSC, AHo, LJB); The Alvin J. Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO (LSC, LJB); Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Canada (RJH, JM); Tobacco Research and Intervention, University of Wisconsin, School of Medicine, Madison, WI (TB); Department of Medicine, Washington University School of Medicine, St. Louis, MO (RC); Department of Genetics, Washington University School of Medicine, St. Louis, MO (NS); Cancer Prevention Institute of California, Fremont, CA (IC); Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN (BD, JW, PY); Department of Community and Family Medicine, Geisel School of Medicine at Dartmouth, Hanover, NH (YH, CIA); Department of Neurological Surgery, University of California San Francisco, San Francisco, CA (HMH, MRW, JKW); Department of Oncology, University of Sheffield, Sheffield, UK (JHo, PW); Department of Epidemiology, UCLA Fielding School of Public Health, University of California Los Angeles, Los Angeles, CA (CK, ZFZ); Department of Biostatistics & Informatics, University of Colorado Anschutz Medical Campus, Denver, CO (SL); Department of Genetic Epidemiology, University of Goettingen Medical School, Goettingen, Germany (AR, HBi); Comprehensive Cancer Centre, the Netherlands, Utrecht, Netherland & Department for Health Evidence, Radboud University Medical Center, Nijmegen, the Netherlands (KKA); Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, NH (ASA); Department of Epidemiology, Michigan State University, East Lansing, MI (NB); Division of Clinical Epidemiology and Aging Research German Cancer Research Center, German Cancer research Center, Heidelberg, Germany (AKD, HBr); German Cancer Consortium, Heidelberg, Germany (AKD, HBr); Department of Thoracic Surgery, Thoraxklinik at University Hospital

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http://dx.doi.org/10.1093/jnci/djv100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822525PMC
May 2015

Involvement of IL-1 genes in the cellular responses to carbon nanotube exposure.

Cytokine 2015 May 6;73(1):128-37. Epub 2015 Mar 6.

Department of Biological and Chemical Work Environment, National Institute of Occupational Health, Pb 8149 Dep., N-0033 Oslo, Norway. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2015.01.032DOI Listing
May 2015

CTCF mediates the TERT enhancer-promoter interactions in lung cancer cells: identification of a novel enhancer region involved in the regulation of TERT gene.

Int J Cancer 2014 May 14;134(10):2305-13. Epub 2013 Nov 14.

Department of Chemical and Biological Work Environment, National Institute of Occupational Health, Oslo, Norway.

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http://doi.wiley.com/10.1002/ijc.28570
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http://dx.doi.org/10.1002/ijc.28570DOI Listing
May 2014

Breast cancer among nurses: is the intensity of night work related to hormone receptor status?

Am J Epidemiol 2013 Jul 20;178(1):110-7. Epub 2013 Jun 20.

Department of Occupational Medicine and Epidemiology, National Institute of Occupational Health, Pb 8149 Dep, 0033 Oslo, Norway.

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http://dx.doi.org/10.1093/aje/kws428DOI Listing
July 2013

Functional effect of polymorphisms in 15q25 locus on CHRNA5 mRNA, bulky DNA adducts and TP53 mutations.

Int J Cancer 2013 Apr 20;132(8):1811-20. Epub 2012 Oct 20.

Section for Toxicology, Department of Biological and Chemical Working Environment, National Institute of Occupational Health, Oslo, Norway.

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http://dx.doi.org/10.1002/ijc.27870DOI Listing
April 2013

Functional analysis of a lung cancer risk haplotype in the IL1B gene regulatory region.

J Hum Genet 2012 Nov 6;57(11):747-52. Epub 2012 Sep 6.

Department of Chemical and Biological Work Environment, Section of Toxicology, National Institute of Occupational Health, Oslo, Norway.

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http://www.nature.com/articles/jhg2012106
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http://dx.doi.org/10.1038/jhg.2012.106DOI Listing
November 2012

DNA methylation at promoter regions of interleukin 1B, interleukin 6, and interleukin 8 in non-small cell lung cancer.

Cancer Immunol Immunother 2013 Feb 26;62(2):337-45. Epub 2012 Aug 26.

Section for Toxicology, Department of Biological and Chemical Working Environment, National Institute of Occupational Health, PO box 8149 Dep., 0033, Oslo, Norway.

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http://link.springer.com/10.1007/s00262-012-1340-3
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February 2013

DNA methylation of the CYP1A1 enhancer is associated with smoking-induced genetic alterations in human lung.

Int J Cancer 2012 Oct 28;131(7):1509-16. Epub 2012 Feb 28.

Section for Toxicology, Department of Biological and Chemical Working Environment, National Institute of Occupational Health, Oslo, Norway.

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http://doi.wiley.com/10.1002/ijc.27421
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October 2012

Cigarette smoking increases copy number alterations in nonsmall-cell lung cancer.

Proc Natl Acad Sci U S A 2011 Sep 12;108(39):16345-50. Epub 2011 Sep 12.

Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.1102769108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182687PMC
September 2011

Stable serum miRNA profiles as potential tool for non-invasive lung cancer diagnosis.

RNA Biol 2011 May-Jun;8(3):506-16. Epub 2011 May 1.

Biomarker Discovery Center Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.4161/rna.8.3.14994DOI Listing
May 2012

Night work and breast cancer risk among Norwegian nurses: assessment by different exposure metrics.

Am J Epidemiol 2011 Jun 31;173(11):1272-9. Epub 2011 Mar 31.

National Institute of Occupational Health, Oslo, Norway.

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http://dx.doi.org/10.1093/aje/kwr014DOI Listing
June 2011

Meta and pooled analyses of FGFR4 Gly388Arg polymorphism as a cancer prognostic factor.

Eur J Cancer Prev 2011 Jul;20(4):340-7

Department of Experimental Oncology and Laboratories, Fondazione IRCCS, Istituto Nazionale Tumori, Milan, Italy.

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https://insights.ovid.com/crossref?an=00008469-201107000-000
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http://dx.doi.org/10.1097/CEJ.0b013e3283457274DOI Listing
July 2011

The association of microRNA expression with prognosis and progression in early-stage, non-small cell lung adenocarcinoma: a retrospective analysis of three cohorts.

Clin Cancer Res 2011 Apr 24;17(7):1875-82. Epub 2011 Feb 24.

Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-2961DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477786PMC
April 2011

Sex differences in susceptibility to PAHs is an intrinsic property of human lung adenocarcinoma cells.

Lung Cancer 2011 Mar 15;71(3):264-70. Epub 2010 Oct 15.

Section for Toxicology, Department of Chemical and Biological Working Environment, National Institute of Occupational Health, Oslo, Norway.

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http://dx.doi.org/10.1016/j.lungcan.2010.09.006DOI Listing
March 2011

Serum estrogen and tumor-positive estrogen receptor-alpha are strong prognostic classifiers of non-small-cell lung cancer survival in both men and women.

Carcinogenesis 2010 Oct 20;31(10):1778-86. Epub 2010 Aug 20.

Laboratory of Human Carcinogenesis, National Cancer Institute, Center for Cancer Research, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/carcin/bgq156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981456PMC
October 2010

Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium.

J Natl Cancer Inst 2010 Jul 14;102(13):959-71. Epub 2010 Jun 14.

Genetic Epidemiology Group, International Agency for Research on Cancer, 150 Cours Albert Thomas, Lyon Cedex 08, France.

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July 2010

A combination of functional polymorphisms in the CASP8, MMP1, IL10 and SEPS1 genes affects risk of non-small cell lung cancer.

Lung Cancer 2011 Feb 14;71(2):123-9. Epub 2010 May 14.

Section of Toxicology, Department of Chemical and Biological Work Environment, National Institute of Occupational Health, Oslo, Norway.

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February 2011

Importance of CYP1A1 and CYP1B1 in bioactivation of benzo[a]pyrene in human lung cell lines.

Toxicol Lett 2010 Feb 30;192(2):221-8. Epub 2009 Oct 30.

Department of Chemical and Biological Working Environment, National Institute of Occupational Health, Oslo, Norway.

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http://dx.doi.org/10.1016/j.toxlet.2009.10.025DOI Listing
February 2010

The TERT-CLPTM1L lung cancer susceptibility variant associates with higher DNA adduct formation in the lung.

Carcinogenesis 2009 Aug 22;30(8):1368-71. Epub 2009 May 22.

Section of Toxicology, Department of Biological and Chemical Working Environment, National Institute of Occupational Health, N-0033, Oslo, Norway.

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August 2009

A specific interleukin-1B haplotype correlates with high levels of IL1B mRNA in the lung and increased risk of non-small cell lung cancer.

Carcinogenesis 2009 Jul 21;30(7):1186-92. Epub 2009 May 21.

Section of Toxicology, Department of Chemical and Biological Work Environment, National Institute of Occupational Health, Oslo, Norway.

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http://dx.doi.org/10.1093/carcin/bgp122DOI Listing
July 2009

Allele-specific induction of IL1B -31T/C promoter polymorphism by lung carcinogens.

Mutat Res 2008 Oct 9;656(1-2):14-8. Epub 2008 Jul 9.

Section of Toxicology, Department of Chemical and Biological Work Environment, National Institute of Occupational Health, Pb 8149 Dep., N-0033 Oslo, Norway.

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http://dx.doi.org/10.1016/j.mrgentox.2008.06.013DOI Listing
October 2008

A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of non-small cell lung cancer in smokers.

Carcinogenesis 2008 Jun 6;29(6):1164-9. Epub 2008 Feb 6.

Section of Toxicology, Department of Biological and Chemical Work Environment, National Institute of Occupational Health N-0033, Oslo, Norway.

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http://dx.doi.org/10.1093/carcin/bgn020DOI Listing
June 2008

Frequency of TP53 mutations in relation to Arg72Pro genotypes in non small cell lung cancer.

Cancer Epidemiol Biomarkers Prev 2007 Oct;16(10):2077-81

Section of Toxicology, Department of Chemical and Biological Working Environment, National Institute of Occupational Health, P.O. Box 8149 Dep, 0033 Oslo, Norway.

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http://dx.doi.org/10.1158/1055-9965.EPI-07-0153DOI Listing
October 2007

Differential binding of proteins to the IL1B -31 T/C polymorphism in lung epithelial cells.

Cytokine 2007 Apr 22;38(1):43-8. Epub 2007 Jun 22.

Section for Toxicology, Department of Chemical and Biological Working Environment, National Institute of Occupational Health, Oslo, Norway.

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http://dx.doi.org/10.1016/j.cyto.2007.05.001DOI Listing
April 2007

Genome-wide single nucleotide polymorphism analysis of lung cancer risk detects the KLF6 gene.

Cancer Lett 2007 Jun 16;251(2):311-6. Epub 2007 Jan 16.

Department of Experimental Oncology and Laboratories, Istituto Nazionale Tumori, Via G. Venezian 1, 20133 Milan, Italy.

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June 2007

Common polymorphisms in D12S1034 flanking genes RASSF8 and BHLHB3 are not associated with lung adenocarcinoma risk.

Lung Cancer 2007 Apr 27;56(1):1-7. Epub 2006 Dec 27.

Department of Experimental Oncology and Laboratories, Istituto Nazionale Tumori, Via G. Venezian 1, 20133 Milan, Italy.

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http://dx.doi.org/10.1016/j.lungcan.2006.11.008DOI Listing
April 2007

Polymorphisms of dopamine receptor/transporter genes and risk of non-small cell lung cancer.

Lung Cancer 2007 Apr 18;56(1):17-23. Epub 2006 Dec 18.

International Agency for Research on Cancer, Lyon, France.

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http://dx.doi.org/10.1016/j.lungcan.2006.11.007DOI Listing
April 2007

Quantitative analysis of benzo[a]pyrene biotransformation and adduct formation in Ahr knockout mice.

Toxicol Lett 2006 Dec 16;167(3):173-82. Epub 2006 Oct 16.

Section for Toxicology, National Institute of Occupational Health, P.O. Box 8149 Dep., N-0033 Oslo, Norway.

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December 2006

Sex differences in risk of lung cancer: Expression of genes in the PAH bioactivation pathway in relation to smoking and bulky DNA adducts.

Int J Cancer 2006 Aug;119(4):741-4

Department of Toxicology, National Institute of Occupational Health, Oslo, Norway.

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http://dx.doi.org/10.1002/ijc.21891DOI Listing
August 2006

Association of a functional polymorphism in the promoter of the MDM2 gene with risk of nonsmall cell lung cancer.

Int J Cancer 2006 Aug;119(3):718-21

Department of Toxicology, National Institute of Occupational Health, Oslo, Norway.

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http://doi.wiley.com/10.1002/ijc.21872
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August 2006

Msh2 deficiency increases susceptibility to benzo[a]pyrene-induced lymphomagenesis.

Int J Cancer 2006 Jun;118(11):2899-902

Department of Toxicology, National Institute of Occupational Health, Oslo, Norway.

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http://dx.doi.org/10.1002/ijc.21686DOI Listing
June 2006

[Molecular biology in the diagnosis of lung cancer].

Authors:
Aage Haugen

Tidsskr Nor Laegeforen 2005 Dec;125(23):3283-5

Toksikologisk seksjon, Statens arbeidsmiljøinstitutt, Postboks 8149 Dep, 0033 Oslo.

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December 2005

Polymorphisms of DNA repair genes and risk of non-small cell lung cancer.

Carcinogenesis 2006 Mar 29;27(3):560-7. Epub 2005 Sep 29.

Department of Toxicology, National Institute of Occupational Health, Oslo, Norway.

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http://academic.oup.com/carcin/article/27/3/560/2476114/Poly
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http://dx.doi.org/10.1093/carcin/bgi232DOI Listing
March 2006

Interleukin 1 receptor antagonist gene polymorphism and risk of lung cancer: a possible interaction with polymorphisms in the interleukin 1 beta gene.

Lung Cancer 2005 Dec 26;50(3):285-90. Epub 2005 Aug 26.

Department of Toxicology, National Institute of Occupational Health, P.O. Box 8149 Dep, N-0033 Oslo, Norway.

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December 2005

Role of estrogen receptor in regulation of polycyclic aromatic hydrocarbon metabolic activation in lung.

Lung Cancer 2004 Sep;45(3):289-97

Department of Toxicology, National Institute of Occupational Health, PO Box 8149 Dep, N-0033 Oslo, Norway.

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http://dx.doi.org/10.1016/j.lungcan.2004.02.014DOI Listing
September 2004

Polymorphisms of the interleukin-1 beta gene are associated with increased risk of non-small cell lung cancer.

Int J Cancer 2004 Apr;109(3):353-6

International Agency for Research on Cancer, Lyon, France.

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http://dx.doi.org/10.1002/ijc.11695DOI Listing
April 2004

Association of a common polymorphism in the cyclooxygenase 2 gene with risk of non-small cell lung cancer.

Carcinogenesis 2004 Feb 6;25(2):229-35. Epub 2003 Nov 6.

Genome Analysis Group, International Agency for Research on Cancer, 150 Cours Albert Thomas, F-69372 Lyon Cedex 08, France.

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http://dx.doi.org/10.1093/carcin/bgh008DOI Listing
February 2004

Expression of estrogen receptors alpha and beta in human lung tissue and cell lines.

Lung Cancer 2002 Aug;37(2):153-9

Department of Toxicology, National Institute of Occupational Health, P.O. Box 8149 Dep, N-0033 Oslo, Norway.

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http://dx.doi.org/10.1016/s0169-5002(02)00039-9DOI Listing
August 2002

Biotransformation of formaldehyde in cultured human bronchus.

Environ Res 2002 May;89(1):38-42

Department of Toxicology, National Institute of Occupational Health, N-0033 Oslo, Norway.

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http://dx.doi.org/10.1006/enrs.2002.4347DOI Listing
May 2002

Women who smoke: are women more susceptible to tobacco-induced lung cancer?

Authors:
Aage Haugen

Carcinogenesis 2002 Feb;23(2):227-9

Department of Toxicology, National Institute of Occupational Health,PO Box 8149 Dep, N-0033 Oslo, Norway.

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http://dx.doi.org/10.1093/carcin/23.2.227DOI Listing
February 2002