Publications by authors named "Özkan Kocamış"

7 Publications

  • Page 1 of 1

Evaluation of Nasopharyngeal and Conjunctival Swab Samples of Hospitalised Patients with Confirmed COVID-19.

Ocul Immunol Inflamm 2021 Mar 4:1-4. Epub 2021 Mar 4.

Department of Emergency Medicine, Kırşehir Ahi Evran University School of Medicine, Kırşehir, Turkey.

Purpose: To evaluate the results of conjunctival and nasopharyngeal swab tests in patients with confirmed COVID-19.

Methods: This prospective study included 45 patients who were hospitalized for confirmed COVID-19. Nasopharyngeal swab samples were obtained from the patients before hospitalization. Only one eye of each patient was randomly selected for-conjunctival sampling. All participants underwent a complete slit-lamp examination. Conjunctival and nasopharyngeal swab samples were analyzed by reversetranscriptase-polymerase-chain reaction (RT-PCR).

Results: Twenty seven (60%) of the patients were male and 18 (40%) were female. Conjunctival swab was positive in only one (2.22%) patient. None of the COVID-19 patients showed ocular changes and symptoms. There were no abnormalities of the ocular surface, anterior chamber or posterior segment at slit-lamp examination.

Conclusions: The RT-PCR was not high positive in the conjunctiva as in nasopharyngeal swabs. Ocular changes were not common in COVID-19 patients.
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http://dx.doi.org/10.1080/09273948.2020.1838558DOI Listing
March 2021

Localized retinal nerve fiber layer defect in patients with COVID-19.

Arq Bras Oftalmol 2020 Nov-Dec;83(6):562-563

Department of Opthalmology, Kırşehir Ahi Evran University School of Medicine, Kırşehir, Turkey.

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http://dx.doi.org/10.5935/0004-2749.20200109DOI Listing
January 2021

Evaluation of choroidal thickness and choroidal vascularity index during pregnancy.

Can J Ophthalmol 2021 Jan 6. Epub 2021 Jan 6.

Kırşehir Ahi Evran University School of Medicine, Department of Gynecology and Obstetrics, Kırşehir, Turkey.

Objective: To assess the choroidal structural characteristics in the first and third trimesters in pregnant women using enhanced depth imaging optical coherence tomography and binarization method.

Design: Prospective study.

Participants: Twenty-five eyes of 25 pregnant women in the first trimester (group 1) and 25 eyes of 25 pregnant women in the third trimester (group 2) were examined. Healthy age-matched 25 participants were enrolled as a control group (group 3).

Methods: The choroidal thickness (CT) was measured at 3 points; subfoveal, 1500 μm nasal to the fovea, and 1500 μm temporal to the fovea. Total choroidal area, luminal area, stromal area, stroma/lumen ratio, and choroidal vascularity index (CVI) were measured by Image-J software.

Results: The mean subfoveal and nasal CT were statistically significantly increased in group 1 compared with controls (p = 0.005 and p = 0.004, respectively). The mean temporal CT was statistically significantly increased in group 1 compared with groups 2 and 3 (group 1 vs group 2, p = 0.043; group 1 vs group 3, p = 0.011). The mean total choroidal area, stromal area, and luminal area were significantly increased in groups 1 and 2 compared with control group (p < 0.001, p < 0.001, p < 0.001, and p < 0.001, p = 0.002, p = 0.002, respectively). There were no statistically significant differences among groups in terms of mean stroma/lumen ratio and CVI (p = 0.148 and p = 0.312, respectively).

Conclusions: There was a significant increase in subfoveal, temporal, and nasal CT in the first trimester. Total choroidal, stromal, and luminal areas were significantly increased in the first and third trimesters.
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http://dx.doi.org/10.1016/j.jcjo.2020.12.002DOI Listing
January 2021

Repeatability, Reproducibility and Agreement of Central Corneal Thickness Measurements by Two Noncontact Pachymetry Devices.

Med Hypothesis Discov Innov Ophthalmol 2019 ;8(1):34-39

Ahi Evran University Medical Faculty, Department of Ophthalmology, Kirsehir, Turkey.

This study was designed to assess the repeatability, reproducibility, and agreement of Noncontact Pachymetry (NPC) (Topcan TRK-2P) and the non-contact optical low coherence reflectometer (Lenstar LS 900) devices for measuring Central Corneal Thickness (CCT) of healthy corneas. A total of 82 healthy volunteers were evaluated. The first observer used both the TopconTRK-2P and Lenstar 900 devices while the second observer only used the TopconTRK-2P for the measurements. The measurements with either device were repeated three times for each patient, consecutively. The central corneal thickness measurements with the Topcon TRK-2P revealed mean ± Standard Deviation (SD) values of 553.1 ± 36.1 micrometer (µm) for the first observer and 552.3 ± 35.9µm for the second observer and the mean ± SD of CCT was 537.3 ± 34.8µm with the Lenstar 900. The difference between the CCT measurements of the observers using the Topcon TRK-2P (P = 0.142) was insignificant. However, significantly lower measurements were found with the Lenstar 900 compared with the Topcon TRK-2P (P ˂ 0.001). The central corneal thickness measurements obtained by the Topcon TRK-2P were found to have high repeatability for both observers with a lower SD, less than 1% Coefficient of Variation (CV) and higher than 0.99 Intra-Class Correlation Coefficient (ICC) (Observer 1: 3.77 SD, 0.68 CV and 0.995 ICC; the second observer: 3.58 SD, 0.65 CV and 0.995 ICC). There was an excellent inter-observer reproducibility between the two observers for Topcon TRK-2P with 2.71 SD, 0.49 CV, and 0.994 ICC. The Bland-Altman plot showed high agreement between the two devices. These results suggest that the TopconTRK-2P is a reliable device for evaluating CCT in healthy corneas compared with Lenstar 900.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433204PMC
January 2019

Choroid and Retinal Nerve Fiber Layer Thickness in Patients with Chronic Obstructive Pulmonary Disease Exacerbation.

J Ophthalmol 2018 8;2018:1201976. Epub 2018 Jul 8.

Department of Pulmonary Medicine, Faculty of Medicine, Ahi Evran University, Kırşehir, Turkey.

Purpose: We aimed at measuring the choroid and retinal nerve fiber layer thickness with optic coherence tomography (OCT) in patients diagnosed with chronic obstructive pulmonary disease (COPD).

Methods: A total of 60 patients with COPD and 23 healthy controls were evaluated in the scope of this prospective, observational study. COPD patients were divided into two groups as those that were stable and those with an exacerbation based on the Global Initiative for Chronic Obstructive Lung Disease (GOLD) classification. Subfoveal choroid thickness (SFCT) of the patients and the control group was compared by measuring the choroid thickness at points 1000 m nasal and temporal to the fovea and the mean retinal nerve fiber layer (RNFL) thickness.

Results: The subfoveal choroid thickness of the COPD patients in both the exacerbation and stable groups was found to be statistically significantly thinner than the control group (=0.047 and =0.046, resp.). No statistically significant difference was found between the subfoveal choroid thickness of the patients that were stable and those that had an exacerbation (=0.813). No statistically significant difference was found between the mean RNFL, 1000 m nasal, or 1000 m temporal choroid thicknesses of the COPD patients and the control group (=0.263, =0.455, and =0.611, resp.).

Conclusion: Decreased subfoveal choroid thickness was found in the COPD patients both during an exacerbation and in the stable period, when compared to the control group. The mean RNFL thickness was similar in the exacerbation and stable period of the stable COPD patients when compared to the control group. This suggests that ocular findings might be important in terms of COPD morbidity. This trial is registered with www.chictr.org.cn/enIndex.aspx.
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http://dx.doi.org/10.1155/2018/1201976DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079521PMC
July 2018

Necessity of Periodic Ophthalmological Examinations in Binocular B Class Driving Licence Holders Over 50 Years of Age.

Turk J Ophthalmol 2016 Apr 5;46(2):73-76. Epub 2016 Apr 5.

Ahi Evran University Training and Research Hospital, Department of Ophthalmology, Kırşehir, Turkey.

Objective: To determine whether binocular B class driving licence (BBCDL) holders over 50 years old are in compliance with the BBCDL criteria for visual acuity, to determine the age-based prevalence of ophthalmological disorders reducing visual acuity in this group, and to investigate whether periodic ophthalmological examinations are needed in licence holders over 50 years of age.

Materials And Methods: This prospective study enrolled 451 adults over 50 years old having a BBCDL. The study subjects were categorized into 3 age groups as group 1 (51-60 years), group 2 (61-70 years), and group 3 (over 71 years).

Results: The mean age of the subjects was 60.02±7.27 years; 338 (74.9%) were male and 113 (25.1%) were female. The BBCDL criteria were met by 353 (78.3%) subjects whereas 98 (21.7%) subjects did not meet them. Eighty-four (85.7%) of 98 patients not meeting BBCDL criteria still drove. The mean age of the subjects meeting BBCDL criteria (58.82±6.77 years) was significantly lower than the subjects not meeting them (64.34±7.40 years) (p<0.001). The most common pathologies in the individuals still driving despite not meeting BBCDL criteria were senile cataract (38.5%) and diabetic retinopathy (23.1%) in group 1, senile cataract (55.3%) and diabetic retinopathy (14.9%) in group 2, and senile cataract (63.6%) and senile macular degeneration+senile cataract (18.2%) in group 3.

Conclusion: More than a fifth of individuals over 50 years old did not meet the BBCDL criteria, due predominantly to senile cataract, and the majority of these individuals continue to drive. Therefore, we believe that individuals over 50 years old who have a BBCDL should undergo periodic ophthalmological examinations.
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http://dx.doi.org/10.4274/tjo.76258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082253PMC
April 2016

Choroidal thickness in psoriasis.

Int Ophthalmol 2017 Feb 11;37(1):173-177. Epub 2016 May 11.

Department of Ophthalmology, Faculty of Medicine, Ahi Evran University, Bağbaşı, Sahir Kurutluoğlu Cad. No:100, 40100, Kırşehir, Turkey.

Our aim was to compare the choroidal thickness in psoriasis patients and age- and gender-matched healthy volunteers. A total of 38 psoriasis cases and 38 age- and gender-matched controls were evaluated. The left eye was evaluated in all subjects. The choroidal thicknesses were measured at the subfovea and horizontally across the fovea at 500-μm intervals using enhanced depth imaging spectral domain optical coherence tomography. The points of measurement were 1500 µm temporal and nasal to the fovea. Choroidal thicknesses in psoriasis patients were thicker than those in the controls, but these differences were not statistically significant (P > 0.05). A positive correlation was present between the duration of disease and choroidal thickness at certain measurement points, but there was no significant correlation between the Psoriasis Area and Severity Index score and choroidal thickness. There was no significant difference between psoriasis patients and healthy controls in terms of choroidal thickness. However, choroidal thickness was associated with disease duration.
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http://dx.doi.org/10.1007/s10792-016-0252-1DOI Listing
February 2017